{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T17:03:20Z","timestamp":1756573400384,"version":"3.43.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.molimm.2025.07.002","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T11:30:38Z","timestamp":1752579038000},"page":"1-5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["CFH nonsense mutation-mediated pregnancy-associated atypical hemolytic uremic syndrome: Case report"],"prefix":"10.1016","volume":"185","author":[{"given":"Chengjun","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rujuan","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maozhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.molimm.2025.07.002_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1053\/j.ackd.2020.01.002","article-title":"Complement-mediated disorders in pregnancy","volume":"27","author":"Amari Chinchilla","year":"2020","journal-title":"Adv. Chronic Kidney Dis."},{"issue":"1","key":"10.1016\/j.molimm.2025.07.002_bib2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12882-016-0420-6","article-title":"Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients","volume":"18","author":"Besbas","year":"2017","journal-title":"BMC Nephrol."},{"issue":"16","key":"10.1016\/j.molimm.2025.07.002_bib3","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1182\/blood.2022018833","article-title":"Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study","volume":"142","author":"Brocklebank","year":"2023","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.molimm.2025.07.002_bib4","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.2215\/CJN.00280117","article-title":"Hemolytic uremic syndrome in pregnancy and postpartum","volume":"12","author":"Bruel","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol. CJASN"},{"key":"10.1016\/j.molimm.2025.07.002_bib5","doi-asserted-by":"crossref","DOI":"10.1177\/20543581231209009","article-title":"Complement-mediated thrombotic microangiopathy in pregnancy: an educational case report","volume":"10","author":"Bruno","year":"2023","journal-title":"Can. J. Kidney Health Dis."},{"key":"10.1016\/j.molimm.2025.07.002_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/370426","article-title":"Familial atypical hemolytic uremic syndrome: a review of its genetic and clinical aspects","volume":"2012","author":"Bu","year":"2012","journal-title":"Clin. Dev. Immunol."},{"issue":"5","key":"10.1016\/j.molimm.2025.07.002_bib7","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s40620-021-01025-x","article-title":"Pregnancy-triggered atypical hemolytic uremic syndrome (aHUS): a Global aHUS Registry analysis","volume":"34","author":"Fakhouri","year":"2021","journal-title":"J. Nephrol."},{"issue":"5","key":"10.1016\/j.molimm.2025.07.002_bib8","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1007\/s10157-018-1549-3","article-title":"Clinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome","volume":"22","author":"Fujisawa","year":"2018","journal-title":"Clin. Exp. Nephrol."},{"key":"10.1016\/j.molimm.2025.07.002_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.preghy.2018.02.007","article-title":"Thrombotic microangiopathies of pregnancy: differential diagnosis","volume":"12","author":"Gupta","year":"2018","journal-title":"Pregnancy Hypertens."},{"issue":"1","key":"10.1016\/j.molimm.2025.07.002_bib10","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/AOG.0000000000003554","article-title":"Pregnancy-associated atypical hemolytic uremic syndrome: a systematic review","volume":"135","author":"Gupta","year":"2020","journal-title":"Obstet. Gynecol."},{"issue":"8","key":"10.1016\/j.molimm.2025.07.002_bib11","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1038\/sj.emboj.7601052","article-title":"Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome","volume":"25","author":"Jokiranta","year":"2006","journal-title":"EMBO J."},{"issue":"1","key":"10.1016\/j.molimm.2025.07.002_bib12","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1681\/ASN.2005080868","article-title":"Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions","volume":"17","author":"J\u00f3zsi","year":"2006","journal-title":"J. Am. Soc. Nephrol. JASN"},{"issue":"1","key":"10.1016\/j.molimm.2025.07.002_bib13","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2018-226571","article-title":"Recurrent case of pregnancy-induced atypical haemolytic uremic syndrome (P-aHUS)","volume":"12","author":"Kumar","year":"2019","journal-title":"BMJ Case Rep."},{"issue":"8","key":"10.1016\/j.molimm.2025.07.002_bib14","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1172\/JCI16651","article-title":"Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome","volume":"111","author":"Manuelian","year":"2003","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.molimm.2025.07.002_bib15","series-title":"GeneReviews","article-title":"Genetic Atypical Hemolytic-Uremic Syndrome","author":"Noris","year":"1993"},{"issue":"1","key":"10.1016\/j.molimm.2025.07.002_bib16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/jth.13189","article-title":"The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies","volume":"14","author":"Phillips","year":"2016","journal-title":"J. Thromb. Haemost. JTH"},{"key":"10.1016\/j.molimm.2025.07.002_bib17","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.cca.2019.03.1623","article-title":"Whole-exome sequencing detects mutations in pediatric patients with atypical hemolytic uremic syndrome in Taiwan","volume":"494","author":"Tseng","year":"2019","journal-title":"Clin. Chim. Acta Int. J. Clin. Chem."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589025001658?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589025001658?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T13:07:28Z","timestamp":1755004048000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589025001658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":17,"alternative-id":["S0161589025001658"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2025.07.002","relation":{},"ISSN":["0161-5890"],"issn-type":[{"type":"print","value":"0161-5890"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CFH nonsense mutation-mediated pregnancy-associated atypical hemolytic uremic syndrome: Case report","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2025.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}