{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T20:24:54Z","timestamp":1787430294727,"version":"build-2736575974"},"reference-count":10,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82572425"],"award-info":[{"award-number":["82572425"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272150"],"award-info":[{"award-number":["82272150"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Molecular Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.molmed.2026.06.007","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T12:13:01Z","timestamp":1783080781000},"page":"732-734","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hyocholic acids: Third bile acids for neonatal health"],"prefix":"10.1016","volume":"32","author":[{"given":"Jiayu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quazi T.H.","family":"Shubhra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3399-3067","authenticated-orcid":false,"given":"Xiaojun","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molmed.2026.06.007_bb0005","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/s41575-024-00914-3","article-title":"The changing metabolic landscape of bile acids \u2013 keys to metabolism and immune regulation","volume":"21","author":"Mohanty","year":"2024","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molmed.2026.06.007_bb0010","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1126\/science.abk2189","article-title":"Immune-microbe interactions early in life: a determinant of health and disease long term","volume":"376","author":"Brodin","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.molmed.2026.06.007_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2026.04.016","article-title":"Hyocholic acids shape neonatal immune tolerance and microbiota assembly","author":"Zheng","year":"2026","journal-title":"Cell Metab."},{"key":"10.1016\/j.molmed.2026.06.007_bb0020","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41467-025-66619-6","article-title":"Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity","volume":"17","author":"Lamichhane","year":"2026","journal-title":"Nat. Commun."},{"key":"10.1016\/j.molmed.2026.06.007_bb0025","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/s41467-025-56072-w","article-title":"Early life microbial succession in the gut follows common patterns in humans across the globe","volume":"16","author":"Bottino","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.molmed.2026.06.007_bb0030","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1038\/s41590-025-02281-w","article-title":"Microbiota-mediated mechanisms of mucosal immunity across the lifespan","volume":"26","author":"Iliev","year":"2025","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molmed.2026.06.007_bb0035","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.cmet.2020.11.017","article-title":"Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism","volume":"33","author":"Zheng","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.molmed.2026.06.007_bb0040","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1038\/s41590-025-02227-2","article-title":"The role of gut microbial metabolites in the T cell lifecycle","volume":"26","author":"Tran","year":"2025","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molmed.2026.06.007_bb0045","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.molmed.2021.12.006","article-title":"Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation","volume":"28","author":"Thibaut","year":"2022","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.molmed.2026.06.007_bb0050","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/s41590-025-02169-9","article-title":"Antibiotics, microbiota and the calibration of infant vaccine responses","volume":"26","author":"Feng","year":"2025","journal-title":"Nat. Immunol."}],"container-title":["Trends in Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471491426001437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471491426001437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T20:00:15Z","timestamp":1787428815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471491426001437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1471491426001437"],"URL":"https:\/\/doi.org\/10.1016\/j.molmed.2026.06.007","relation":{},"ISSN":["1471-4914"],"issn-type":[{"value":"1471-4914","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hyocholic acids: Third bile acids for neonatal health","name":"articletitle","label":"Article Title"},{"value":"Trends in Molecular Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molmed.2026.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}