{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:06:09Z","timestamp":1792674369323,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Metabolism"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.molmet.2023.101737","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T11:56:22Z","timestamp":1683892582000},"page":"101737","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration"],"prefix":"10.1016","volume":"73","author":[{"given":"Valentina","family":"Bianco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Korbelius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nemanja","family":"Vujic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"Akhmetshina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melina","family":"Amor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Kolb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Pirchheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Bradic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina B.","family":"Kuentzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Buerger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Schauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huyen T.T.","family":"Phan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Bulfon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Hoefler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1357-7573","authenticated-orcid":false,"given":"Dagmar","family":"Kratky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molmet.2023.101737_bib1","first-page":"421","article-title":"Lingual and gastric lipases","volume":"6","author":"Hamosh","year":"1990","journal-title":"Nutr. Burbank Los Angel. Cty. Calif"},{"key":"10.1016\/j.molmet.2023.101737_bib2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev.nutr.17.1.141","article-title":"Structure and function of pancreatic lipase and colipase","volume":"17","author":"Lowe","year":"1997","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.molmet.2023.101737_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-2760(96)00085-9","article-title":"Molecular biology of enzymes involved with cholesterol ester hydrolysis in mammalian tissues","volume":"1303","author":"Hui","year":"1996","journal-title":"Biochim. Biophys. Acta BBA - Lipids Lipid Metab."},{"key":"10.1016\/j.molmet.2023.101737_bib4","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/ajcn\/33.5.1108","article-title":"Intestinal fat digestion, absorption, and transport A review","volume":"33","author":"Friedman","year":"1980","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.molmet.2023.101737_bib5","first-page":"12","article-title":"Intestinal lipid absorption","volume":"296","author":"Iqbal","year":"2009","journal-title":"Endocrinol Metab"},{"key":"10.1016\/j.molmet.2023.101737_bib6","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.bbalip.2011.09.013","article-title":"Gut Triglyceride Production","volume":"1821","author":"Pan","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.molmet.2023.101737_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/MOL.0b013e32813fa2e2","article-title":"Intestinal cholesterol transport proteins: an update and beyond","volume":"18","author":"Levy","year":"2007","journal-title":"Curr Opin Lipidol"},{"key":"10.1016\/j.molmet.2023.101737_bib8","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/MOL.0000000000000084","article-title":"Intestinal lipid absorption and lipoprotein formation","volume":"25","author":"Hussain","year":"2014","journal-title":"Curr Opin Lipidol"},{"key":"10.1016\/j.molmet.2023.101737_bib9","first-page":"72","article-title":"Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly","volume":"1486","author":"Gordon","year":"2000","journal-title":"Biochim. Biophys. Acta BBA - Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.molmet.2023.101737_bib10","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/gut.52.6.834","article-title":"Mobilisation of enterocyte fat stores by oral glucose in humans","volume":"52","author":"Robertson","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.molmet.2023.101737_bib11","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrm.2017.76","article-title":"Cytosolic lipolysis and lipophagy: two sides of the same coin","volume":"18","author":"Zechner","year":"2017","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.molmet.2023.101737_bib12","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/282041","article-title":"Lipophagy: connecting autophagy and lipid metabolism","volume":"2012","author":"Singh","year":"2012","journal-title":"Int. J. Cell Biol."},{"key":"10.1016\/j.molmet.2023.101737_bib13","doi-asserted-by":"crossref","first-page":"2952","DOI":"10.1016\/S0021-9258(19)69707-3","article-title":"Purification of the lysosomal acid lipase from human liver and its role in lysosomal lipid hydrolysis","volume":"256","author":"Warner","year":"1981","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.molmet.2023.101737_bib14","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.cmet.2011.03.023","article-title":"Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase","volume":"13","author":"Ouimet","year":"2011","journal-title":"Cell Metabol"},{"key":"10.1016\/j.molmet.2023.101737_bib15","doi-asserted-by":"crossref","first-page":"17977","DOI":"10.1074\/jbc.M116.724054","article-title":"Lysosomal acid lipase hydrolyzes retinyl ester and affects retinoid turnover","volume":"291","author":"Grumet","year":"2016","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.molmet.2023.101737_bib16","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1091\/mbc.e13-06-0324","article-title":"Autophagosomes contribute to intracellular lipid distribution in enterocytes","volume":"25","author":"Khaldoun","year":"2014","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.molmet.2023.101737_bib17","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2021109997","article-title":"Feeding activates FGF15-SHP-TFEB-mediated lipophagy in the gut","volume":"41","author":"Seok","year":"2022","journal-title":"EMBO J"},{"key":"10.1016\/j.molmet.2023.101737_bib18","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.jhep.2013.02.014","article-title":"Cholesteryl ester storage disease: review of the findings in 135 reported patients with an underdiagnosed disease","volume":"58","author":"Bernstein","year":"2013","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.molmet.2023.101737_bib19","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S2468-1253(17)30052-3","article-title":"Wolman's disease and cholesteryl ester storage disorder: the phenotypic spectrum of lysosomal acid lipase deficiency","volume":"2","author":"Pericleous","year":"2017","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1016\/j.molmet.2023.101737_bib20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.prp.2003.11.001","article-title":"Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy","volume":"200","author":"Boldrini","year":"2004","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.molmet.2023.101737_bib21","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.bbalip.2019.01.007","article-title":"Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation","volume":"1864","author":"Leopold","year":"2019","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1016\/j.molmet.2023.101737_bib22","doi-asserted-by":"crossref","first-page":"33275","DOI":"10.1074\/jbc.M204935200","article-title":"Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine","volume":"277","author":"Madison","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.molmet.2023.101737_bib23","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.celrep.2019.07.030","article-title":"ATGL\/CGI-58-Dependent hydrolysis of a lipid storage pool in murine enterocytes","volume":"28","author":"Korbelius","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.molmet.2023.101737_bib24","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot4986","article-title":"Hematoxylin and eosin staining of tissue and cell sections","volume":"2008","author":"Fischer","year":"2008","journal-title":"Cold Spring Harb Protoc"},{"key":"10.1016\/j.molmet.2023.101737_bib25","doi-asserted-by":"crossref","first-page":"33122","DOI":"10.18632\/oncotarget.16529","article-title":"Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE\u2212\/\u2212 mice","volume":"8","author":"Vujic","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.molmet.2023.101737_bib26","doi-asserted-by":"crossref","unstructured":"Khalifeh-Soltani, A.; Gupta, D.; Ha, A.; Iqbal, J.; Hussain, M.; Podolsky, M.J., et\u00a0al Mfge8 regulates enterocyte lipid storage by promoting enterocyte triglyceride hydrolase activity. JCI Insight 1, e87418, doi:10.1172\/jci.insight.87418.","DOI":"10.1172\/jci.insight.87418"},{"key":"10.1016\/j.molmet.2023.101737_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221910416","article-title":"Defective lysosomal lipolysis causes prenatal lipid accumulation and exacerbates immediately after birth","volume":"22","author":"Kuentzel","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.molmet.2023.101737_bib29","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/B978-0-12-800280-3.00010-4","article-title":"Measurement of lipolysis","volume":"538","author":"Schweiger","year":"2014","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.molmet.2023.101737_bib30","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1017\/S1431927603445911","article-title":"A\u00a0program for automated tilt series acquisition on Tecnai microscopes using prediction of specimen position","volume":"9","author":"Mastronarde","year":"2003","journal-title":"Microsc Microanal"},{"key":"10.1016\/j.molmet.2023.101737_bib31","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1194\/jlr.D700041-JLR200","article-title":"Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics","volume":"49","author":"Matyash","year":"2008","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib32","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.3390\/cells10102619","article-title":"Impaired bile acid metabolism and gut dysbiosis in mice lacking lysosomal acid lipase","volume":"10","author":"Sachdev","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.molmet.2023.101737_bib33","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0022-2275(20)31157-3","article-title":"Lysosomal acid lipase-deficient mice: depletion of white and Brown fat, severe hepatosplenomegaly, and shortened life span","volume":"42","author":"Du","year":"2001","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101510","article-title":"Off-target effects of the lysosomal acid lipase inhibitors lalistat-1 and lalistat-2 on neutral lipid hydrolases","volume":"61","author":"Bradi\u0107","year":"2022","journal-title":"Mol Metabol"},{"key":"10.1016\/j.molmet.2023.101737_bib35","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1007\/s00125-016-3968-6","article-title":"Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice","volume":"59","author":"Radovi\u0107","year":"2016","journal-title":"Diabetologia"},{"key":"10.1016\/j.molmet.2023.101737_bib36","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.bbalip.2018.01.011","article-title":"Lysosomal acid lipase regulates fatty acid channeling in Brown adipose tissue to maintain thermogenesis","volume":"1863","author":"Duta-Mare","year":"2018","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.molmet.2023.101737_bib37","doi-asserted-by":"crossref","first-page":"32157","DOI":"10.1074\/jbc.M202838200","article-title":"Separation and characterization of late endosomal membrane domains","volume":"277","author":"Kobayashi","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.molmet.2023.101737_bib38","doi-asserted-by":"crossref","first-page":"8067","DOI":"10.3390\/ijms21218067","article-title":"The emerging and diverse roles of bis(monoacylglycero) phosphate lipids in cellular physiology and disease","volume":"21","author":"Showalter","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.molmet.2023.101737_bib39","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.taap.2014.06.014","article-title":"Di-22:6-Bis(Monoacylglycerol)Phosphate: a clinical biomarker of drug-induced phospholipidosis for drug development and safety assessment","volume":"279","author":"Liu","year":"2014","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.molmet.2023.101737_bib40","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1194\/jlr.M038232","article-title":"Selective reduction of bis(Monoacylglycero)Phosphate ameliorates the storage burden in a THP-1 macrophage model of gaucher disease","volume":"54","author":"Hein","year":"2013","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib41","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1046\/j.1471-4159.2003.01602.x","article-title":"Analysis of phospholipid molecular species in brains from patients with infantile and juvenile neuronal-ceroid lipofuscinosis using liquid chromatography-electrospray ionization mass spectrometry","volume":"84","author":"K\u00e4kel\u00e4","year":"2003","journal-title":"J\u00a0Neurochem"},{"key":"10.1016\/j.molmet.2023.101737_bib42","unstructured":"Holness, C.L.; Simmons, D.L. Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. vol. 7."},{"key":"10.1016\/j.molmet.2023.101737_bib43","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1182\/blood-2014-04-568691","article-title":"Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in\u00a0vivo","volume":"124","author":"Iqbal","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.molmet.2023.101737_bib44","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.cell.2019.05.054","article-title":"Lipid-associated macrophages control metabolic homeostasis in a trem2-dependent manner","volume":"178","author":"Jaitin","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.molmet.2023.101737_bib45","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.cell.2017.05.018","article-title":"A\u00a0unique microglia type associated with restricting development of Alzheimer's disease","volume":"169","author":"Keren-Shaul","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.molmet.2023.101737_bib46","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.cell.2015.01.049","article-title":"TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model","volume":"160","author":"Wang","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.molmet.2023.101737_bib47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bbrc.2014.10.063","article-title":"Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver","volume":"454","author":"Lopez","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.molmet.2023.101737_bib48","doi-asserted-by":"crossref","first-page":"G836","DOI":"10.1152\/ajpgi.00243.2014","article-title":"Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice","volume":"307","author":"Aqul","year":"2014","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.molmet.2023.101737_bib49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1042\/BJ20071043","article-title":"Effect of lysosomal storage on bis(Monoacylglycero)Phosphate","volume":"411","author":"Meikle","year":"2008","journal-title":"Biochem J"},{"key":"10.1016\/j.molmet.2023.101737_bib50","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1194\/jlr.M093351","article-title":"Metabolic disease and ABHD6 alter the circulating bis(Monoacylglycerol)Phosphate profile in mice and humans","volume":"60","author":"Grabner","year":"2019","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib51","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.plefa.2009.09.006","article-title":"Bis(Monoacylglycero)Phosphate, a peculiar phospholipid to control the fate of cholesterol: implications in pathology","volume":"81","author":"Hullin-Matsuda","year":"2009","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"10.1016\/j.molmet.2023.101737_bib52","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1007\/s11064-010-0337-6","article-title":"Biological function of the cellular lipid BMP\u2014BMP as a key activator for cholesterol sorting and membrane digestion","volume":"36","author":"Gallala","year":"2011","journal-title":"Neurochem Res"},{"key":"10.1016\/j.molmet.2023.101737_bib53","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1194\/jlr.M092460","article-title":"Intestinal basolateral lipid substrate transport is linked to chylomicron secretion and is regulated by ApoC-III","volume":"60","author":"Li","year":"2019","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib54","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0022-2275(20)42005-X","article-title":"Tissue and cellular specific expression of murine lysosomal acid lipase MRNA and protein","volume":"37","author":"Du","year":"1996","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.molmet.2023.101737_bib55","doi-asserted-by":"crossref","first-page":"26279","DOI":"10.1074\/jbc.M110.134775","article-title":"Exosome secretion ameliorates lysosomal storage of cholesterol in niemann-pick type C disease","volume":"285","author":"Strauss","year":"2010","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.molmet.2023.101737_bib56","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.imlet.2006.09.005","article-title":"Exosomes: from biogenesis and secretion to biological function","volume":"107","author":"Keller","year":"2006","journal-title":"Immunol Lett"}],"container-title":["Molecular Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212877823000716?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212877823000716?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:33:36Z","timestamp":1761957216000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212877823000716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":55,"alternative-id":["S2212877823000716"],"URL":"https:\/\/doi.org\/10.1016\/j.molmet.2023.101737","relation":{},"ISSN":["2212-8778"],"issn-type":[{"value":"2212-8778","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration","name":"articletitle","label":"Article Title"},{"value":"Molecular Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molmet.2023.101737","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"101737"}}