{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:48:05Z","timestamp":1792550885643,"version":"4.5.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"CIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Metabolism"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.molmet.2025.102235","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T03:07:36Z","timestamp":1755745656000},"page":"102235","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["GLP-1R signaling does not modify the severity of experimental graft versus host disease"],"prefix":"10.1016","volume":"100","author":[{"given":"Bernardo","family":"Yusta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi Kin","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne","family":"Matthews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline A.","family":"Koehler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie L.","family":"Baggio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KW Annie","family":"Bang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6688-8127","authenticated-orcid":false,"given":"Daniel J.","family":"Drucker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.molmet.2025.102235_bib1","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1007\/s00125-023-05906-7","article-title":"The expanding incretin universe: from basic biology to clinical translation","volume":"66","author":"Drucker","year":"2023","journal-title":"Diabetologia"},{"key":"10.1016\/j.molmet.2025.102235_bib2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1146\/annurev-physiol-021113-170317","article-title":"Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2","volume":"76","author":"Drucker","year":"2014","journal-title":"Annu Rev Physiol"},{"issue":"12","key":"10.1016\/j.molmet.2025.102235_bib3","doi-asserted-by":"crossref","first-page":"4217","DOI":"10.1172\/JCI97233","article-title":"Discovery, characterization, and clinical development of the glucagon-like peptides","volume":"127","author":"Drucker","year":"2017","journal-title":"J Clin Investig"},{"issue":"2","key":"10.1016\/j.molmet.2025.102235_bib4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1210\/endrev\/bnaa032","article-title":"Revisiting the complexity of GLP-1 action from sites of synthesis to receptor activation","volume":"42","author":"McLean","year":"2021","journal-title":"Endocr Rev"},{"issue":"10","key":"10.1016\/j.molmet.2025.102235_bib5","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.2337\/db14-0100","article-title":"GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering","volume":"63","author":"Kahles","year":"2014","journal-title":"Diabetes"},{"issue":"11","key":"10.1016\/j.molmet.2025.102235_bib6","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1038\/nm.2513","article-title":"Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells","volume":"17","author":"Ellingsgaard","year":"2011","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.molmet.2025.102235_bib7","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/j.celrep.2017.10.008","article-title":"Enteroendocrine L cells sense LPS after gut barrier injury to enhance GLP-1 secretion","volume":"21","author":"Lebrun","year":"2017","journal-title":"Cell Rep"},{"issue":"2","key":"10.1016\/j.molmet.2025.102235_bib8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2337\/db13-0903","article-title":"Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: involvement of the GLP-1 pathway","volume":"63","author":"Nguyen","year":"2014","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.molmet.2025.102235_bib9","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cmet.2015.02.005","article-title":"GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7","volume":"21","author":"Koehler","year":"2015","journal-title":"Cell Metab"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib10","doi-asserted-by":"crossref","first-page":"G288","DOI":"10.1152\/ajpgi.00453.2006","article-title":"Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats","volume":"293","author":"Simonsen","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"10","key":"10.1016\/j.molmet.2025.102235_bib11","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1016\/j.cmet.2022.08.003","article-title":"Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation","volume":"34","author":"Wong","year":"2022","journal-title":"Cell Metab"},{"issue":"7","key":"10.1016\/j.molmet.2025.102235_bib12","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.2337\/db14-1577","article-title":"GLP-1 receptor (GLP-1R) agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte (IEL) GLP-1R","volume":"64","author":"Yusta","year":"2015","journal-title":"Diabetes"},{"issue":"9","key":"10.1016\/j.molmet.2025.102235_bib13","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1097\/MIB.0000000000000847","article-title":"GLP-1 induces barrier protective expression in brunner's glands and regulates colonic inflammation","volume":"22","author":"Bang-Berthelsen","year":"2016","journal-title":"Inflamm Bowel Dis"},{"issue":"16","key":"10.1016\/j.molmet.2025.102235_bib14","doi-asserted-by":"crossref","first-page":"8044","DOI":"10.18632\/aging.204953","article-title":"The alleviating effect and mechanism of GLP-1 on ulcerative colitis","volume":"15","author":"Wang","year":"2023","journal-title":"Aging (Albany NY)"},{"issue":"3","key":"10.1016\/j.molmet.2025.102235_bib15","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/imm.13784","article-title":"GLP-1 receptor agonists alleviate colonic inflammation by modulating intestinal microbiota and the function of group 3 innate lymphoid cells","volume":"172","author":"Sun","year":"2024","journal-title":"Immunology"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib16","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00280-012-1882-2","article-title":"Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine","volume":"70","author":"Kissow","year":"2012","journal-title":"Cancer Chemother Pharmacol"},{"issue":"3","key":"10.1016\/j.molmet.2025.102235_bib17","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/j.2040-4603.2018.tb00039.x","article-title":"Glucagon-like Peptide-2 and the regulation of intestinal growth and function","volume":"8","author":"Brubaker","year":"2018","journal-title":"Compr Physiol"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib18","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/jgh.13808","article-title":"Glucagon-like peptide-1 analog, liraglutide, improves visceral sensation and gut permeability in rats","volume":"33","author":"Nozu","year":"2018","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.molmet.2025.102235_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.175029","article-title":"Cholecystokinin and glucagon-like peptide-1 analogues regulate intestinal tight junction, inflammation, dopaminergic neurons and alpha-synuclein accumulation in the Colon of two parkinson's disease mouse models","volume":"926","author":"Su","year":"2022","journal-title":"Eur J Pharmacol"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib20","doi-asserted-by":"crossref","first-page":"C1260","DOI":"10.1152\/ajpcell.00345.2021","article-title":"In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function","volume":"322","author":"Voetmann","year":"2022","journal-title":"Am J Physiol Cell Physiol"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib21","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.cmet.2024.05.001","article-title":"Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule","volume":"36","author":"Ben Nasr","year":"2024","journal-title":"Cell Metab"},{"issue":"3","key":"10.1016\/j.molmet.2025.102235_bib22","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/TP.0000000000002448","article-title":"Liraglutide, a glucagon-like Peptide-1 receptor agonist, attenuates development of cardiac Allograft vasculopathy in a murine heart transplant model","volume":"103","author":"Wang","year":"2019","journal-title":"Transplantation"},{"key":"10.1016\/j.molmet.2025.102235_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1551136","article-title":"GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism","volume":"16","author":"Peng","year":"2025","journal-title":"Front Immunol"},{"key":"10.1016\/j.molmet.2025.102235_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1148209","article-title":"Glucagon-like peptide-1: a multi-faceted anti-inflammatory agent","volume":"14","author":"Mehdi","year":"2023","journal-title":"Front Immunol"},{"issue":"6706","key":"10.1016\/j.molmet.2025.102235_bib25","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1126\/science.adn4128","article-title":"The benefits of GLP-1 drugs beyond obesity","volume":"385","author":"Drucker","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.molmet.2025.102235_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.793588","article-title":"Glucagon-like Peptide-1 is associated with systemic inflammation in pediatric patients treated with hematopoietic stem cell transplantation","volume":"12","author":"Ebbesen","year":"2021","journal-title":"Front Immunol"},{"issue":"10","key":"10.1016\/j.molmet.2025.102235_bib27","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2024-089862","article-title":"Semaglutide treatment for PRevention of toxicity in high-dosE chemotherapy with autologous haematopoietic stem-cell transplantation (PROTECT): study protocol for a randomised, double-blind, placebo-controlled, investigator-initiated study","volume":"14","author":"Sorum","year":"2024","journal-title":"BMJ Open"},{"issue":"11","key":"10.1016\/j.molmet.2025.102235_bib28","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/nm1196-1254","article-title":"Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene","volume":"2","author":"Scrocchi","year":"1996","journal-title":"Nat Med"},{"key":"10.1016\/j.molmet.2025.102235_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2020.101008","article-title":"The gut hormone receptor GIPR links energy availability to the control of hematopoiesis","volume":"39","author":"Pujadas","year":"2020","journal-title":"Mol Metabol"},{"issue":"3","key":"10.1016\/j.molmet.2025.102235_bib30","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.174825","article-title":"Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice","volume":"10","author":"Hammoud","year":"2024","journal-title":"JCI Insight"},{"issue":"22","key":"10.1016\/j.molmet.2025.102235_bib31","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.153732","article-title":"Differential importance of endothelial and hematopoietic cell GLP-1Rs for cardiometabolic versus hepatic actions of semaglutide","volume":"6","author":"McLean","year":"2021","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib32","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.jacbts.2018.09.004","article-title":"The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE(-\/-) and LDLr(-\/-) mice by a mechanism that includes inflammatory pathways","volume":"3","author":"Rakipovski","year":"2018","journal-title":"JACC Basic Transl Sci"},{"key":"10.1016\/j.molmet.2025.102235_bib33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jim.2014.01.014","article-title":"Optimization of murine small intestine leukocyte isolation for global immune phenotype analysis","volume":"405","author":"Goodyear","year":"2014","journal-title":"J Immunol Methods"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib34","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1210\/en.2012-1937","article-title":"GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic Male ApoE-\/- mice","volume":"154","author":"Panjwani","year":"2013","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.molmet.2025.102235_bib35","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.136907","article-title":"Loss of Glp2r signaling activates hepatic stellate cells and exacerbates diet-induced steatohepatitis in mice","volume":"5","author":"Fuchs","year":"2020","journal-title":"JCI Insight"},{"issue":"7","key":"10.1016\/j.molmet.2025.102235_bib36","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nmeth.3869","article-title":"DADA2: high-resolution sample inference from Illumina amplicon data","volume":"13","author":"Callahan","year":"2016","journal-title":"Nat Methods"},{"issue":"4","key":"10.1016\/j.molmet.2025.102235_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0061217","article-title":"Phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data","volume":"8","author":"McMurdie","year":"2013","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.molmet.2025.102235_bib38","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib39","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib40","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41587-020-0548-6","article-title":"PICRUSt2 for prediction of metagenome functions","volume":"38","author":"Douglas","year":"2020","journal-title":"Nat Biotechnol"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib41","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.immuni.2019.06.003","article-title":"T cell recruitment to the intestinal stem cell compartment drives immune-mediated intestinal damage after allogeneic transplantation","volume":"51","author":"Fu","year":"2019","journal-title":"Immunity"},{"issue":"42","key":"10.1016\/j.molmet.2025.102235_bib42","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aay8556","article-title":"T cell-derived interferon-gamma programs stem cell death in immune-mediated intestinal damage","volume":"4","author":"Takashima","year":"2019","journal-title":"Sci Immunol"},{"issue":"8","key":"10.1016\/j.molmet.2025.102235_bib43","doi-asserted-by":"crossref","first-page":"3204","DOI":"10.1182\/blood.V90.8.3204","article-title":"Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines","volume":"90","author":"Hill","year":"1997","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.molmet.2025.102235_bib44","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1182\/blood.2019000952","article-title":"Cytokines and costimulation in acute graft-versus-host disease","volume":"136","author":"Hill","year":"2020","journal-title":"Blood"},{"issue":"23","key":"10.1016\/j.molmet.2025.102235_bib45","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1056\/NEJMra2026131","article-title":"Cytokine storm","volume":"383","author":"Fajgenbaum","year":"2020","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.molmet.2025.102235_bib46","first-page":"1325","article-title":"Acute and chronic graft-versus-host disease: clinical manifestations, prophylaxis, and treatment","volume":"76","author":"Deeg","year":"1986","journal-title":"J Natl Cancer Inst"},{"issue":"9","key":"10.1016\/j.molmet.2025.102235_bib47","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1172\/JCI7894","article-title":"Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets","volume":"105","author":"Nikolic","year":"2000","journal-title":"J Clin Investig"},{"issue":"5","key":"10.1016\/j.molmet.2025.102235_bib48","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41577-021-00590-3","article-title":"The precursors of CD8(+) tissue resident memory T cells: from lymphoid organs to infected tissues","volume":"22","author":"Kok","year":"2022","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib49","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.bbmt.2015.10.001","article-title":"Acute graft-versus-host disease: novel biological insights","volume":"22","author":"Teshima","year":"2016","journal-title":"Biol Blood Marrow Transplant"},{"issue":"11","key":"10.1016\/j.molmet.2025.102235_bib50","doi-asserted-by":"crossref","first-page":"4970","DOI":"10.1172\/JCI99261","article-title":"Survival signal REG3alpha prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease","volume":"128","author":"Zhao","year":"2018","journal-title":"J Clin Investig"},{"issue":"2","key":"10.1016\/j.molmet.2025.102235_bib51","doi-asserted-by":"crossref","first-page":"G461","DOI":"10.1152\/ajpgi.00424.2006","article-title":"Role of glial cell-line derived neurotropic factor family receptor alpha2 in the actions of the glucagon-like peptides on the murine intestine","volume":"293","author":"McDonagh","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"11","key":"10.1016\/j.molmet.2025.102235_bib52","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1016\/j.celrep.2019.05.055","article-title":"Distinct neural sites of GLP-1R expression mediate physiological versus pharmacological control of incretin action","volume":"27","author":"Varin","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.molmet.2025.102235_bib53","doi-asserted-by":"crossref","first-page":"646","DOI":"10.2337\/diabetes.47.4.646","article-title":"Mouse pancreatic beta cells exhibit preserved glucose competence after disruption of the glucagon-like peptide 1 receptor gene","volume":"47","author":"Flamez","year":"1998","journal-title":"Diabetes"},{"issue":"2","key":"10.1016\/j.molmet.2025.102235_bib54","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/sj.bmt.1703328","article-title":"A two-phase pathogenesis of graft-versus-host disease in mice","volume":"29","author":"van Leeuwen","year":"2002","journal-title":"Bone Marrow Transplant"},{"issue":"2","key":"10.1016\/j.molmet.2025.102235_bib55","doi-asserted-by":"crossref","first-page":"724","DOI":"10.4049\/jimmunol.1102630","article-title":"Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease","volume":"188","author":"Li","year":"2012","journal-title":"J Immunol"},{"issue":"5","key":"10.1016\/j.molmet.2025.102235_bib56","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1172\/JCI125797","article-title":"The gut microbiota and graft-versus-host disease","volume":"129","author":"Fredricks","year":"2019","journal-title":"J Clin Investig"},{"issue":"1","key":"10.1016\/j.molmet.2025.102235_bib57","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.cmet.2023.11.009","article-title":"Central glucagon-like peptide 1 receptor activation inhibits toll-like receptor agonist-induced inflammation","volume":"36","author":"Wong","year":"2024","journal-title":"Cell Metab"},{"issue":"17","key":"10.1016\/j.molmet.2025.102235_bib58","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.jacc.2024.08.028","article-title":"Inflammation in obesity-related HFpEF: the STEP-HFpEF program","volume":"84","author":"Verma","year":"2024","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.molmet.2025.102235_bib59","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.2337\/dc19-0883","article-title":"Oral semaglutide versus empagliflozin in patients with type 2 diabetes uncontrolled on metformin: the PIONEER 2 trial","volume":"42","author":"Rodbard","year":"2019","journal-title":"Diabetes Care"}],"container-title":["Molecular Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212877825001425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212877825001425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T23:02:51Z","timestamp":1758668571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212877825001425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":59,"alternative-id":["S2212877825001425"],"URL":"https:\/\/doi.org\/10.1016\/j.molmet.2025.102235","relation":{},"ISSN":["2212-8778"],"issn-type":[{"value":"2212-8778","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GLP-1R signaling does not modify the severity of experimental graft versus host disease","name":"articletitle","label":"Article Title"},{"value":"Molecular Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molmet.2025.102235","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"102235"}}