{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:07:37Z","timestamp":1791824857981,"version":"4.3.4"},"reference-count":42,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"vor","delay-in-days":368,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.molp.2020.01.004","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T19:32:57Z","timestamp":1579289577000},"page":"732-744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":266,"title":["Hydrogen Sulfide Positively Regulates Abscisic Acid Signaling through Persulfidation of SnRK2.6 in Guard Cells"],"prefix":"10.1016","volume":"13","author":[{"given":"Sisi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglei","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiyun","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijuan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3061-8998","authenticated-orcid":false,"given":"Jisheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molp.2020.01.004_bib1","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1111\/nph.12469","article-title":"Open Stomata 1 (OST1) is limiting in abscisic acid responses of Arabidopsis guard cells","volume":"200","author":"Acharya","year":"2013","journal-title":"New Phytol."},{"key":"10.1016\/j.molp.2020.01.004_bib2","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1104\/pp.109.147975","article-title":"An O-acetylserine(thiol) lyase homolog with L-cysteine desulfhydrase activity regulates cysteine homeostasis in Arabidopsis","volume":"152","author":"Alvarez","year":"2010","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib3","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1104\/pp.15.00009","article-title":"S-Sulfhydration: a cysteine posttranslational modification in plant systems","volume":"168","author":"Aroca","year":"2015","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib4","doi-asserted-by":"crossref","first-page":"4915","DOI":"10.1093\/jxb\/erx294","article-title":"Persulfidation proteome reveals the regulation of protein function by hydrogen sulfide in diverse biological processes in Arabidopsis","volume":"68","author":"Aroca","year":"2017","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.molp.2020.01.004_bib5","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1093\/pcp\/pcx056","article-title":"Hydrogen sulfide regulates the cytosolic\/nuclear partitioning of glyceraldehyde-3-phosphate dehydrogenase by enhancing its nuclear localization","volume":"58","author":"Aroca","year":"2017","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib6","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1104\/pp.106.079327","article-title":"Identification of features regulating OST1 kinase activity and OST1 function in guard cells","volume":"141","author":"Belin","year":"2006","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib7","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1105\/tpc.109.067702","article-title":"Abscisic acid represses growth of the Arabidopsis embryonic axis after germination by enhancing auxin signaling","volume":"21","author":"Belin","year":"2009","journal-title":"Plant Cell"},{"key":"10.1016\/j.molp.2020.01.004_bib8","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.1093\/jxb\/erz031","article-title":"Nitric oxide and hydrogen sulfide in plants: which comes first?","volume":"70","author":"Corpas","year":"2019","journal-title":"J. Exp. Bot."},{"key":"10.1016\/j.molp.2020.01.004_bib9","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1146\/annurev-arplant-042809-112122","article-title":"Abscisic acid: emergence of a core signaling network","volume":"61","author":"Cutler","year":"2010","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.molp.2020.01.004_bib10","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nature08599","article-title":"In\u00a0vitro reconstitution of an abscisic acid signalling pathway","volume":"462","author":"Fujii","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.molp.2020.01.004_bib11","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/jipb.12004","article-title":"Hydrogen sulfide regulates ethylene-induced stomatal closure in Arabidopsis thaliana","volume":"55","author":"Hou","year":"2013","journal-title":"J. Integr. Plant Biol."},{"key":"10.1016\/j.molp.2020.01.004_bib12","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/aob\/mcr252","article-title":"Abscisic acidand CO2 signalling via calcium sensitivity priming in guard cells, new CDPK mutant phenotypes and a method for improved resolution of stomatal stimulus-response analyses","volume":"109","author":"Hubbard","year":"2012","journal-title":"Ann. Bot."},{"key":"10.1016\/j.molp.2020.01.004_bib13","doi-asserted-by":"crossref","first-page":"8251","DOI":"10.1038\/srep08251","article-title":"Hydrogen sulfide modulates actin-dependent auxin transport viaregulating ABPs results in changing of root development in Arabidopsis","volume":"5","author":"Jia","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molp.2020.01.004_bib14","doi-asserted-by":"crossref","first-page":"39702","DOI":"10.1038\/srep39702","article-title":"Hydrogen sulfide - cysteine cycle system enhances cadmium tolerance through alleviating cadmium-induced oxidative stress and ion toxicity in Arabidopsis roots","volume":"6","author":"Jia","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molp.2020.01.004_bib15","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.3389\/fpls.2018.01517","article-title":"Ethylene-induced hydrogen sulfide negatively regulates ethylene biosynthesis by persulfidation of ACO in tomato under osmotic stress","volume":"9","author":"Jia","year":"2018","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.molp.2020.01.004_bib16","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.envexpbot.2018.06.034","article-title":"Hydrogen sulfide - cysteine cycle plays a positive role in Arabidopsis responses to Copper Oxide nanoparticles stress","volume":"155","author":"Jia","year":"2018","journal-title":"Environ. Exp. Bot."},{"key":"10.1016\/j.molp.2020.01.004_bib17","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1105\/tpc.112.105049","article-title":"Nitrated cyclic GMP modulates guard cell signaling in Arabidopsis","volume":"25","author":"Joudoi","year":"2013","journal-title":"Plant Cell"},{"key":"10.1016\/j.molp.2020.01.004_bib18","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1146\/annurev-arplant-042809-112226","article-title":"Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signaling","volume":"61","author":"Kim","year":"2010","journal-title":"Annu. Rev. Plant Biol."},{"key":"10.1016\/j.molp.2020.01.004_bib19","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/aob\/mcl006","article-title":"Regulation of sulfate assimilation in Arabidopsis and beyond","volume":"97","author":"Kopriva","year":"2006","journal-title":"Ann. Bot."},{"key":"10.1016\/j.molp.2020.01.004_bib20","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1093\/emboj\/cdg277","article-title":"NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis","volume":"22","author":"Kwak","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.molp.2020.01.004_bib21","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s00709-013-0592-x","article-title":"Hydrogen sulfide is involved in maintaining ion homeostasis via regulating plasma membrane Na+\/H+ antiporter system in the hydrogen peroxide-dependent manner in salt-stress Arabidopsis thaliana root","volume":"251","author":"Li","year":"2014","journal-title":"Protoplasma"},{"key":"10.1016\/j.molp.2020.01.004_bib22","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jplph.2014.12.018","article-title":"Hydrogen sulfide acts as a downstream signal molecule in salicylic acid-induced heat tolerance in maize (Zea mays L.) seedlings","volume":"177","author":"Li","year":"2015","journal-title":"J. Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib23","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1104\/pp.18.00838","article-title":"Hydrogen sulfide disturbs actin polymerization via S-sulfhydration resulting in stunted root hair growth","volume":"178","author":"Li","year":"2018","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib24","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1126\/science.1172408","article-title":"Regulators of PP2C phosphatase activity function as abscisic acid sensors","volume":"324","author":"Ma","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.molp.2020.01.004_bib25","doi-asserted-by":"crossref","first-page":"ra72","DOI":"10.1126\/scisignal.2000464","article-title":"H2S signals through protein S-sulfhydration","volume":"2","author":"Mustafa","year":"2009","journal-title":"Sci. Signal."},{"key":"10.1016\/j.molp.2020.01.004_bib26","doi-asserted-by":"crossref","first-page":"3089","DOI":"10.1105\/tpc.007906","article-title":"Arabidopsis OST1 protein kinase mediates the regulation of stomatal aperture by abscisic acid and acts upstream of reactive oxygen species production","volume":"14","author":"Mustilli","year":"2002","journal-title":"Plant Cell"},{"key":"10.1016\/j.molp.2020.01.004_bib27","doi-asserted-by":"crossref","first-page":"21259","DOI":"10.1073\/pnas.1118651109","article-title":"Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases","volume":"108","author":"Ng","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.molp.2020.01.004_bib28","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1055\/s-2007-965424","article-title":"Characterization of cysteine-degrading and H2S-releasing enzymes of higher plants: from the field to the test tube and back","volume":"9","author":"Papenbrock","year":"2007","journal-title":"Plant Biol. (Stuttg.)"},{"key":"10.1016\/j.molp.2020.01.004_bib29","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1126\/science.1173041","article-title":"Abscisic acid inhibits type 2C protein phosphatases via the PYR\/PYL family of START proteins","volume":"324","author":"Park","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.molp.2020.01.004_bib30","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nrm3391","article-title":"H2S signalling through protein sulfhydration and beyond","volume":"13","author":"Paul","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.molp.2020.01.004_bib31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1042\/BJ20091221","article-title":"Threonine at position 306 of the KAT1 potassium channel is essential for channel activity and is a target site for ABA-activated SnRK2\/OST1\/SnRK2.6 protein kinase","volume":"424","author":"Sato","year":"2009","journal-title":"Biochem. J."},{"key":"10.1016\/j.molp.2020.01.004_bib32","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1104\/pp.114.245373","article-title":"Hydrogen sulfide generated by l-cysteine desulfhydrase acts upstream of nitric oxide to modulate abscisic acid-dependent stomatal closure","volume":"166","author":"Scuffi","year":"2014","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib33","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1126\/science.1215106","article-title":"Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases","volume":"335","author":"Soon","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.molp.2020.01.004_bib34","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1104\/pp.108.129494","article-title":"NaCl-induced alternations of cellular and tissue ion fluxes in roots of salt-resistant and salt-sensitive poplar species","volume":"149","author":"Sun","year":"2009","journal-title":"Plant Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib35","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-313X.2004.02219.x","article-title":"Visualization of protein interactions in living plant cells\u00a0using bimolecular fluorescence complementation","volume":"40","author":"Walter","year":"2004","journal-title":"Plant J."},{"key":"10.1016\/j.molp.2020.01.004_bib36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1073\/pnas.1423481112","article-title":"Nitric oxide negatively regulates abscisic acid signaling in guard cells by S-nitrosylation of OST1","volume":"112","author":"Wang","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.molp.2020.01.004_bib37","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.molp.2015.11.010","article-title":"Hydrogen sulfide activates S-type anion channel via OST1 and Ca2+ modules","volume":"9","author":"Wang","year":"2016","journal-title":"Mol. Plant"},{"key":"10.1016\/j.molp.2020.01.004_bib38","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1071\/FP14162","article-title":"Heterotrimeric G-proteins involved in the MeJA regulated ion flux and stomatal closure in Arabidopsis thaliana","volume":"42","author":"Yan","year":"2015","journal-title":"Funct. Plant Biol."},{"issue":"12","key":"10.1016\/j.molp.2020.01.004_bib39","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1093\/pcp\/pcf188","article-title":"ABA-activated SnRK2 protein kinase is required for dehydration stress signaling in Arabidopsis","volume":"43","author":"Yoshida","year":"2002","journal-title":"Plant Cell Physiol."},{"key":"10.1016\/j.molp.2020.01.004_bib40","doi-asserted-by":"crossref","first-page":"5310","DOI":"10.1074\/jbc.M509820200","article-title":"The regulatory domain of SRK2E\/OST1\/SnRK2.6 interacts with ABI1 and integrates abscisic acid (ABA) and osmotic stress signals controlling stomatal closure in Arabidopsis","volume":"281","author":"Yoshida","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molp.2020.01.004_bib41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1046\/j.1365-313X.1998.00188.x","article-title":"Determination of intracellular Ca2+ in cells of intact wheat roots: loading of acetoxymethyl ester of Fluo-3 under low temperature","volume":"15","author":"Zhang","year":"2004","journal-title":"Plant J."},{"key":"10.1016\/j.molp.2020.01.004_bib42","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1093\/jxb\/erq424","article-title":"Heterotrimeric G-protein regulation of ROS signalling and calcium currents in Arabidopsis guard cells","volume":"62","author":"Zhang","year":"2011","journal-title":"J. Exp. Bot."}],"container-title":["Molecular Plant"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1674205220300046?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1674205220300046?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T12:02:47Z","timestamp":1761652967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1674205220300046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S1674205220300046"],"URL":"https:\/\/doi.org\/10.1016\/j.molp.2020.01.004","relation":{},"ISSN":["1674-2052"],"issn-type":[{"value":"1674-2052","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrogen Sulfide Positively Regulates Abscisic Acid Signaling through Persulfidation of SnRK2.6 in Guard Cells","name":"articletitle","label":"Article Title"},{"value":"Molecular Plant","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molp.2020.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 The Author 2020","name":"copyright","label":"Copyright"}]}}