{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:30:48Z","timestamp":1793637048982,"version":"4.5.1"},"reference-count":45,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFF1000100"],"award-info":[{"award-number":["2023YFF1000100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2023ZD04076"],"award-info":[{"award-number":["2023ZD04076"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20186"],"award-info":[{"award-number":["U23A20186"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Plant"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.molp.2026.08.011","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:35:34Z","timestamp":1788968134000},"page":"2169-2180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["HAIant (\u667a\u7136\u4f53): A human-centered AI framework for secure, personalized intelligence augmentation in biological research"],"prefix":"10.1016","volume":"19","author":[{"given":"Yunlong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunming","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhilong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfeng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qishuai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendi","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youkun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachen","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinpeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanzhen","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruozhuo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangguo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaiwen","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8519-5833","authenticated-orcid":false,"given":"Lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molp.2026.08.011_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2018.e00938","article-title":"State-of-the-art in artificial neural network applications: A survey","volume":"4","author":"Abiodun","year":"2018","journal-title":"Heliyon"},{"key":"10.1016\/j.molp.2026.08.011_bib2","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/s41586-024-07487-w","article-title":"Accurate structure prediction of biomolecular interactions with AlphaFold 3","volume":"630","author":"Abramson","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib3","first-page":"419","article-title":"Firecracker: Lightweight virtualization for serverless applications","author":"Agache","year":"2020","journal-title":"Proc. USENIX Symp. Netw. Syst. Des. Implement. (NSDI)"},{"key":"10.1016\/j.molp.2026.08.011_bib4","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1038\/s41586-025-10014-0","article-title":"Advancing regulatory variant effect prediction with AlphaGenome","volume":"649","author":"Avsec","year":"2026","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib5","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1145\/1090191.1080123","article-title":"Rigorous specification and conformance testing techniques for network protocols, as applied to TCP, UDP, and sockets","volume":"35","author":"Bishop","year":"2005","journal-title":"ACM Comput. Commun. Rev."},{"key":"10.1016\/j.molp.2026.08.011_bib6","article-title":"Sparks of artificial general intelligence: Early experiments with GPT-4","author":"Bubeck","year":"2023","journal-title":"arXiv"},{"key":"10.1016\/j.molp.2026.08.011_bib7","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1007\/s11948-020-00276-4","article-title":"Towards Transparency by Design for Artificial Intelligence","volume":"26","author":"Felzmann","year":"2020","journal-title":"Sci. Eng. Ethics"},{"key":"10.1016\/j.molp.2026.08.011_bib8","article-title":"GPTQ: Accurate post-training quantization for generative pre-trained transformers","author":"Frantar","year":"2022","journal-title":"arXiv"},{"key":"10.1016\/j.molp.2026.08.011_bib9","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.14778\/3554821.3554842","article-title":"SQLite: Past, present, and future","volume":"15","author":"Gaffney","year":"2022","journal-title":"Proc. VLDB Endow."},{"key":"10.1016\/j.molp.2026.08.011_bib10","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1002\/ajim.23037","article-title":"Artificial intelligence: Implications for the future of work","volume":"62","author":"Howard","year":"2019","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.molp.2026.08.011_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/3487890","article-title":"Artificial intelligence security: Threats and countermeasures","volume":"55","author":"Hu","year":"2021","journal-title":"ACM Comput. Surv."},{"key":"10.1016\/j.molp.2026.08.011_bib12","first-page":"7036","article-title":"Adaptive-RAG: Learning to adapt retrieval-augmented large language models through question complexity","author":"Jeong","year":"2024","journal-title":"Proc. Conf. North Am. Chapter Assoc. Comput. Linguist. Hum. Lang. Technol. (NAACL-HLT)"},{"key":"10.1016\/j.molp.2026.08.011_bib13","doi-asserted-by":"crossref","first-page":"6769","DOI":"10.18653\/v1\/2020.emnlp-main.550","article-title":"Dense passage retrieval for open-domain question answering","author":"Karpukhin","year":"2020","journal-title":"Proc. Conf. Empir. Methods Nat. Lang. Process. (EMNLP)"},{"key":"10.1016\/j.molp.2026.08.011_bib14","article-title":"Your brain on ChatGPT: Accumulation of cognitive debt when using an AI assistant for essay writing task","author":"Kosmyna","year":"2025","journal-title":"arXiv"},{"key":"10.1016\/j.molp.2026.08.011_bib15","article-title":"Upgrading HTTPS in mid-air: An empirical study of strict transport security and key pinning","author":"Kranch","year":"2015","journal-title":"Proc. Netw. Distrib. Syst. Secur. Symp. (NDSS)"},{"key":"10.1016\/j.molp.2026.08.011_bib16","first-page":"1097","article-title":"ImageNet classification with deep convolutional neural networks","volume":"25","author":"Krizhevsky","year":"2012","journal-title":"Adv. Neurcal Inf. Process. Syst."},{"key":"10.1016\/j.molp.2026.08.011_bib17","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/nature14539","article-title":"Deep learning","volume":"521","author":"LeCun","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib18","first-page":"9459","article-title":"Retrieval-augmented generation for knowledge-intensive NLP tasks","volume":"33","author":"Lewis","year":"2020","journal-title":"Adv. Neural Inf. Process. Syst."},{"key":"10.1016\/j.molp.2026.08.011_bib19","doi-asserted-by":"crossref","DOI":"10.1109\/TPAMI.2026.3707616","article-title":"LoRASculpt: Harmonious Low-Rank Adaptation for Multimodal Large Language Models","author":"Liang","year":"2026","journal-title":"IEEE Trans. Pattern Anal. Mach. Intell."},{"key":"10.1016\/j.molp.2026.08.011_bib20","article-title":"Formalizing and benchmarking prompt injection attacks and defenses","author":"Liu","year":"2024","journal-title":"Proc. USENIX Secur. Symp."},{"key":"10.1016\/j.molp.2026.08.011_bib21","article-title":"PlotGDP: An AI agent for bioinformatics plotting","author":"Luo","year":"2026","journal-title":"bioRxiv"},{"key":"10.1016\/j.molp.2026.08.011_bib22","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1080\/0952813X.2021.1964003","article-title":"The risks associated with artificial general intelligence: A systematic review","volume":"35","author":"McLean","year":"2023","journal-title":"J. Exp. Theor. Artif. Intell."},{"key":"10.1016\/j.molp.2026.08.011_bib23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41586-024-07146-0","article-title":"Artificial intelligence and illusions of understanding in scientific research","volume":"627","author":"Messeri","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib24","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/s00521-026-12266-x","article-title":"Indirect prompt injection in large language models","volume":"38","author":"Milani","year":"2026","journal-title":"Neural Comput. Appl."},{"key":"10.1016\/j.molp.2026.08.011_bib25","doi-asserted-by":"crossref","DOI":"10.1126\/science.adq9356","article-title":"The Turing Test and our shifting conceptions of intelligence","volume":"385","author":"Mitchell","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.molp.2026.08.011_bib26","article-title":"Automating customer service using LangChain: Building custom open-source GPT chatbot for organizations","author":"Pandya","year":"2023","journal-title":"arXiv"},{"key":"10.1016\/j.molp.2026.08.011_bib27","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/s41586-019-1424-8","article-title":"Towards artificial general intelligence with hybrid Tianjic chip architecture","volume":"572","author":"Pei","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib28","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.molp.2026.08.011_bib29","series-title":"R: A Language and Environment for Statistical Computing","year":"2024"},{"key":"10.1016\/j.molp.2026.08.011_bib30","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s42979-021-00557-0","article-title":"AI-driven cybersecurity: An overview, security intelligence modeling and research directions","volume":"2","author":"Sarker","year":"2021","journal-title":"SN Comput. Sci."},{"key":"10.1016\/j.molp.2026.08.011_bib31","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/msb.2011.75","article-title":"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega","volume":"7","author":"Sievers","year":"2011","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.molp.2026.08.011_bib32","first-page":"1","article-title":"Small and fast LLMs on commodity hardware: Post-training quantization in llama","author":"Sparrenberg","year":"2025","journal-title":"cpp. Proc. IEEE Int. Conf. Data Sci. Adv. Anal. (DSAA)"},{"key":"10.1016\/j.molp.2026.08.011_bib33","doi-asserted-by":"crossref","first-page":"101611","DOI":"10.1016\/j.patter.2026.101611","article-title":"BioMaster: Multi-agent system for automated bioinformatics analysis workflow","volume":"7","author":"Su","year":"2026","journal-title":"Patterns"},{"key":"10.1016\/j.molp.2026.08.011_bib34","first-page":"5998","article-title":"Attention is all you need","volume":"30","author":"Vaswani","year":"2017","journal-title":"Adv. Neural Inf. Process. Syst."},{"key":"10.1016\/j.molp.2026.08.011_bib35","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1007\/s13347-021-00477-0","article-title":"Transparency and the black box problem: Why we do not trust AI","volume":"34","author":"Von Eschenbach","year":"2021","journal-title":"Philos. Technol."},{"key":"10.1016\/j.molp.2026.08.011_bib36","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41586-023-06221-2","article-title":"Scientific discovery in the age of artificial intelligence","volume":"620","author":"Wang","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib37","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/s41586-023-06415-8","article-title":"De novo design of protein structure and function with RFdiffusion","volume":"620","author":"Watson","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.molp.2026.08.011_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.xplc.2025.101240","article-title":"AutoGP: An intelligent breeding platform for enhancing maize genomic selection","volume":"6","author":"Wu","year":"2025","journal-title":"Plant Commun."},{"key":"10.1016\/j.molp.2026.08.011_bib39","first-page":"641","article-title":"C-Pack: Packed resources for general Chinese embeddings","author":"Xiao","year":"2024","journal-title":"Proc. ACM SIGIR Conf. Res. Dev. Inf. Retr."},{"key":"10.1016\/j.molp.2026.08.011_bib40","article-title":"Qwen3 technical report","author":"Yang","year":"2025","journal-title":"arXiv"},{"key":"10.1016\/j.molp.2026.08.011_bib41","doi-asserted-by":"crossref","first-page":"54608","DOI":"10.1109\/ACCESS.2024.3389497","article-title":"GPT (generative pre-trained transformer)\u2014A comprehensive review on enabling technologies, potential applications, emerging challenges, and future directions","volume":"12","author":"Yenduri","year":"2024","journal-title":"IEEE Access"},{"key":"10.1016\/j.molp.2026.08.011_bib42","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.molp.2026.03.010","article-title":"PlantScience.ai: An LLM-powered virtual scientist for plant science","volume":"19","author":"Yu","year":"2026","journal-title":"Mol. Plant"},{"key":"10.1016\/j.molp.2026.08.011_bib43","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/s41592-026-03036-7","article-title":"Highly accurate ab initio gene annotation with ANNEVO","volume":"23","author":"Zhang","year":"2026","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molp.2026.08.011_bib44","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s44387-025-00019-5","article-title":"Exploring the role of large language models in the scientific method: From hypothesis to discovery","volume":"1","author":"Zhang","year":"2025","journal-title":"npj Artif. Intell."},{"key":"10.1016\/j.molp.2026.08.011_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s41019-025-00335-5","article-title":"Retrieval-augmented generation for AI-generated content: A survey","volume":"11","author":"Zhao","year":"2026","journal-title":"Data Sci. Eng."}],"container-title":["Molecular Plant"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1674205226002698?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1674205226002698?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:20:01Z","timestamp":1793636401000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1674205226002698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":45,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1674205226002698"],"URL":"https:\/\/doi.org\/10.1016\/j.molp.2026.08.011","relation":{},"ISSN":["1674-2052"],"issn-type":[{"value":"1674-2052","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HAIant (\u667a\u7136\u4f53): A human-centered AI framework for secure, personalized intelligence augmentation in biological research","name":"articletitle","label":"Article Title"},{"value":"Molecular Plant","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molp.2026.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, and Chinese Society for Plant Biology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}