{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T07:29:30Z","timestamp":1784359770578,"version":"3.55.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surgery (Oxford)"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.mpsur.2015.08.002","type":"journal-article","created":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T03:38:09Z","timestamp":1445225889000},"page":"565-571","source":"Crossref","is-referenced-by-count":15,"title":["Sepsis in the intensive care unit"],"prefix":"10.1016","volume":"33","author":[{"given":"Sean R.","family":"Bennett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mpsur.2015.08.002_bib1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/CCM.0b013e31819285f0","article-title":"A\u00a0prospective, observational registry of patients with severe sepsis: the Canadian Treatment and Response Registry","volume":"37","author":"Martin","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib2","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1097\/01.CCM.0000050454.01978.3B","article-title":"2001 SCCM\/ESICM\/ACCP\/ATS\/SIS international sepsis definitions conference","volume":"31","author":"Levy","year":"2003","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib3","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev-pathol-011110-130327","article-title":"The pathogenesis of sepsis","volume":"6","author":"Stearns-Kurosawa","year":"2011","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.mpsur.2015.08.002_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/CCM.0000000000000723","article-title":"Surviving sepsis campaign: association between performance metrics and outcomes in a 7.5-year study","volume":"43","author":"Levy","year":"2015","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib5","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/CCM.0b013e31827e83af","article-title":"Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012","volume":"41","author":"Dellinger","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib6","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1056\/NEJMoa040232","article-title":"A\u00a0comparison of albumin and saline for fluid resuscitation in the intensive care unit","volume":"350","author":"Finfer","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib7","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1056\/NEJMoa1209759","article-title":"CHEST Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group: hydroxyethyl starch or saline for fluid resuscitation in intensive care","volume":"367","author":"Myburgh","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000567.pub4","article-title":"Colloids versus crystalloids for fluid resuscitation in critically ill patients","author":"Perel","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.mpsur.2015.08.002_bib9","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1056\/NEJMoa1401602","article-title":"A\u00a0randomized trial of protocol-based care for early septic shock","volume":"370","author":"Yealy","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib10","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1097\/CCM.0b013e318174db05","article-title":"Actual incidence of global left ventricular hypokinesia in adult septic shock","volume":"36","author":"Vieillard-Baron","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib11","article-title":"Corticosteroids for treating severe sepsis and septic shock","author":"Annane","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.mpsur.2015.08.002_bib12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa071366","article-title":"Hydrocortisone therapy for patients with septic shock","volume":"358","author":"Sprung","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib13","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1056\/NEJMoa010307","article-title":"Early goal-directed therapy in the treatment of severe sepsis and septic shock","volume":"345","author":"Rivers","year":"2001","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib14","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1056\/NEJM199902113400601","article-title":"A\u00a0multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion requirements in Critical Care Investigators, Canadian Critical Care Trials Group","volume":"340","author":"Hebert","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib15","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","article-title":"Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome","volume":"342","author":"The Acute Respiratory Distress Syndrome Network","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib16","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1056\/NEJMoa011300","article-title":"Intensive insulin therapy in critically ill patients","volume":"345","author":"Van den Berghe","year":"2001","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib17","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1056\/NEJMoa0810625","article-title":"Intensive versus conventional glucose control in critically ill patients","volume":"360","author":"NICE-SUGAR Study Investigators","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib18","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1097\/CCM.0b013e318174dcf0","article-title":"Current practice in nutritional support and its association with mortality in septic patients-results from a national, prospective, multicenter study","volume":"36","author":"Schadler","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib19","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1007\/s00134-003-1711-5","article-title":"Early enteral immunonutrition in patients with severe sepsis: results of an interim analysis of a randomized multicentre clinical trial","volume":"29","author":"Bertolini","year":"2003","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.mpsur.2015.08.002_bib20","first-page":"214","article-title":"Design, organisation and staffing of the intensive care unit","volume":"30","author":"Bennett","year":"2012","journal-title":"Surgery"},{"key":"10.1016\/j.mpsur.2015.08.002_bib21","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1478-5153.2010.00400.x","article-title":"Nursing leadership at the crossroads: evidence-based practice \u2018Matching Michigan-minimizing catheter related\u00a0blood stream infections\u2019","volume":"16","author":"Goeschel","year":"2011","journal-title":"Nurs Crit Care"}],"container-title":["Surgery (Oxford)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0263931915001702?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0263931915001702?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T17:50:35Z","timestamp":1537293035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0263931915001702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S0263931915001702"],"URL":"https:\/\/doi.org\/10.1016\/j.mpsur.2015.08.002","relation":{},"ISSN":["0263-9319"],"issn-type":[{"value":"0263-9319","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]}}}