{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:10:28Z","timestamp":1764781828950,"version":"3.46.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002923","name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","doi-asserted-by":"publisher","award":["PIP No. 0316"],"award-info":[{"award-number":["PIP No. 0316"]}],"id":[{"id":"10.13039\/501100002923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.mrfmmm.2009.12.005","type":"journal-article","created":{"date-parts":[[2009,12,23]],"date-time":"2009-12-23T04:30:46Z","timestamp":1261542646000},"page":"90-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Relationship between heterochromatic interstitial telomeric sequences and chromosome damage induced by the radiomimetic compound streptonigrin in Chinese hamster ovary cells"],"prefix":"10.1016","volume":"684","author":[{"given":"Julieta","family":"S\u00e1nchez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha S.","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro D.","family":"Bolz\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrfmmm.2009.12.005_bib1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.mrrev.2007.08.006","article-title":"Endings in the middle: current knowledge of interstitial telomeric sequences","volume":"658","author":"Lin","year":"2008","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000167807","article-title":"Telomeric repeats far from the ends: mechanisms of origin and role in evolution","volume":"122","author":"Ru\u00edz-Herrera","year":"2008","journal-title":"Cytogenet. Genome Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1159\/000015171","article-title":"Two extended arrays of a satellite DNA sequence at the centromere and at the short-arm telomere of Chinese hamster chromosome 5","volume":"83","author":"Faravelli","year":"1998","journal-title":"Cytogenet. Cell Genet."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.mrrev.2005.12.003","article-title":"Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations","volume":"612","author":"Bolz\u00e1n","year":"2006","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/geno.1994.1581","article-title":"Telomeric and nontelomeric (TTAGGG)n sequences in gene amplification and chromosome stability","volume":"24","author":"Bertoni","year":"1994","journal-title":"Genomics"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib6","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0027-5107(94)90304-2","article-title":"Analysis of restriction enzyme-induced chromosome aberrations in the interstitial telomeric repeat sequences of CHO and CHE cells by FISH","volume":"307","author":"Balajee","year":"1994","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib7","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1007\/BF00352299","article-title":"Spontaneous and radiation-induced chromosomal breakage at interstitial telomeric sites","volume":"104","author":"Slijepcevic","year":"1996","journal-title":"Chromosoma"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/gcc.2870080103","article-title":"Chromosomal radiosensitivity at intrachromosomal telomeric sites","volume":"8","author":"Alvarez","year":"1993","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib9","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF00713065","article-title":"High frequency of mutagen-induced chromatid exchanges at interstitial telomere-like DNA s\u00e9quense blocks of Chinese hamster cells","volume":"3","author":"Fern\u00e1ndez","year":"1995","journal-title":"Chromosome Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/095530098142653","article-title":"Chromosome healing, telomere capture and mechanisms of radiation-induced chromosome breakage","volume":"73","author":"Slijepcevic","year":"1998","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0027-5107(01)00162-2","article-title":"FISH analysis of telomeric repeat sequences and their involvement in chromosomal aberrations induced by radiomimetic compounds in hamster cells","volume":"479","author":"Bolz\u00e1n","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.mrfmmm.2009.06.002","article-title":"Effect of bleomycin on interstitial telomeric sequences of immortalized Chinese hamster ovary cells","volume":"669","author":"S\u00e1nchez","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib13","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1159\/000134516","article-title":"Instability of CHO chromosomes containing interstitial telomeric sequences originating from Chinese hamster chromosome 10","volume":"76","author":"Slijepcevic","year":"1997","journal-title":"Cytogenet. Cell Genet."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/mutage\/13.1.45","article-title":"Telomeres and radiation-induced chromosome breakage","volume":"13","author":"Slijepcevic","year":"1998","journal-title":"Mutagenesis"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000077476","article-title":"Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells","volume":"104","author":"Desmaze","year":"2004","journal-title":"Cytogenet. Genome Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib16","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1383-5742(00)00062-4","article-title":"Genotoxicity of streptonigrin: a review","volume":"488","author":"Bolz\u00e1n","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib17","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/em.20051","article-title":"Analysis of streptonigrin-induced incomplete chromosome elements and interstitial fragments in Chinese hamster cells using a telomeric PNA probe","volume":"44","author":"Bolz\u00e1n","year":"2004","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib18","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/251156a0","article-title":"New Giemsa method for differential staining of sister chromatids","volume":"251","author":"Perry","year":"1974","journal-title":"Nature"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib19","first-page":"69","article-title":"Measurements of telomere length on individual chromosomes by image cytometry","volume":"vol. 64","author":"Poon","year":"2001"},{"year":"1957","series-title":"Statistical Tables for Biological, Agricultural and Medical Research","author":"Fisher","key":"10.1016\/j.mrfmmm.2009.12.005_bib20"},{"key":"10.1016\/j.mrfmmm.2009.12.005_bib21","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/carcin\/19.2.259","article-title":"Recombination involving interstitial telomere repeat-like sequences promotes chromosomal instability in Chinese hamster cells","volume":"19","author":"Day","year":"1998","journal-title":"Carcinogenesis"}],"container-title":["Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027510709003765?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027510709003765?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T09:29:15Z","timestamp":1764667755000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0027510709003765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":21,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0027510709003765"],"URL":"https:\/\/doi.org\/10.1016\/j.mrfmmm.2009.12.005","relation":{},"ISSN":["1386-1964"],"issn-type":[{"type":"print","value":"1386-1964"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between heterochromatic interstitial telomeric sequences and chromosome damage induced by the radiomimetic compound streptonigrin in Chinese hamster ovary cells","name":"articletitle","label":"Article Title"},{"value":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mrfmmm.2009.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}