{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:53:56Z","timestamp":1790643236349,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005670","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Rio Grande do Norte","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007391","name":"Association pour la Recherche sur le Cancer","doi-asserted-by":"publisher","award":["PJA 20131200165"],"award-info":[{"award-number":["PJA 20131200165"]}],"id":[{"id":"10.13039\/100007391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.mrfmmm.2016.01.004","type":"journal-article","created":{"date-parts":[[2016,1,16]],"date-time":"2016-01-16T17:36:43Z","timestamp":1452965803000},"page":"25-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["XPC deficiency is related to APE1 and OGG1 expression and function"],"prefix":"10.1016","volume":"784-785","author":[{"given":"Julliane Tamara Ara\u00fajo","family":"de Melo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Rafaela","family":"de Souza Timoteo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tirzah Braz Petta","family":"Lajus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Alves","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja Cristhina","family":"de Souza-Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Frederico Martins","family":"Menck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Campalans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Pablo","family":"Radicella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Teixeira","family":"Vessoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alysson Renato","family":"Muotri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0642-3162","authenticated-orcid":false,"given":"Lucymara Fassarella","family":"Agnez-Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0005","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.mrrev.2011.12.005","article-title":"DNA damage by singlet oxygen and cellular protective mechanisms","volume":"751","author":"Agnez-Lima","year":"2012","journal-title":"Mutat. Res.\/Rev. Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0010","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/cr.2008.8","article-title":"Early steps in the DNA base excision\/single-strand interruption repair pathway in mammalian cells","volume":"18","author":"Hedge","year":"2008","journal-title":"Cell. Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0015","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1089\/ars.2012.5036","article-title":"Oxidative DNA damage and nucleotide excision repair","volume":"18","author":"Melis","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0020","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1007\/s00018-009-8737-y","article-title":"DNA repair in mammalian cells: nucleotide excision repair: variations on versatility","volume":"66","author":"Nouspikel","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0025","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.pneurobio.2011.04.013","article-title":"DNA repair deficiency in neurodegeneration","volume":"94","author":"Jeppesen","year":"2011","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0030","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1590\/S1415-47572014000200008","article-title":"DNA repair diseases: what do they tell us about cancer and aging?","volume":"2","author":"Menck","year":"2014","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0035","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/cr.2008.2","article-title":"Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology","volume":"18","author":"Shuck","year":"2008","journal-title":"Cell Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0040","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1038\/sj.emboj.7601277","article-title":"New functions of XPC in the protection of human skin cells from oxidative damage","volume":"25","author":"D'Errico","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0045","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.freeradbiomed.2013.03.026","article-title":"Nucleotide excision repair activity on DNA damage induced by photoactivated methylene blue","volume":"61","author":"Berra","year":"2013","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0050","doi-asserted-by":"crossref","first-page":"30832","DOI":"10.1074\/jbc.M204814200","article-title":"The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA","volume":"277","author":"Tuo","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0055","doi-asserted-by":"crossref","first-page":"8232","DOI":"10.1038\/sj.onc.1206027","article-title":"A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage","volume":"21","author":"Osterod","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0060","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1038\/sj.onc.1205443","article-title":"Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product","volume":"21","author":"Sunesen","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0065","doi-asserted-by":"crossref","first-page":"9270","DOI":"10.1074\/jbc.M807006200","article-title":"Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase","volume":"284","author":"Muftuoglu","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0070","doi-asserted-by":"crossref","first-page":"8675","DOI":"10.1038\/sj.onc.1205994","article-title":"Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B","volume":"21","author":"Stevnsner","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0075","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1093\/nar\/gkm404","article-title":"Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates","volume":"35","author":"Wong","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0080","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/cbf.3100","article-title":"A review on protein-protein interaction network of APE1\/Ref-1 and its associated biological functions","volume":"33","author":"Thakur","year":"2015","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0085","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.molcel.2004.12.029","article-title":"A vital role for Ape1\/Ref1 protein in repairing spontaneous DNA damage in human cells","volume":"17","author":"Fung","year":"2005","journal-title":"Mol. Cell."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0090","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.dnarep.2006.10.010","article-title":"Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein","volume":"6","author":"Mitra","year":"2007","journal-title":"DNA Repair"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0095","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1089\/ars.2005.7.367","article-title":"The intracellular localization of APE1\/Ref-1: more than a passive phenomenon?","volume":"7","author":"Tell","year":"2005","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0100","doi-asserted-by":"crossref","first-page":"14871","DOI":"10.1074\/jbc.M109.069591","article-title":"Identification and characterization of mitochondrial targeting sequence of human apurinic\/apyrimidinic endonuclease 1","volume":"285","author":"Li","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0105","first-page":"185","article-title":"An immortalized xeroderma pigmentosum, group C, cell line which replicates SV40 shuttle vectors","volume":"183","author":"Daya-Grosjean","year":"1987","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0110","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1038\/jid.2009.409","article-title":"A prevalent mutation with founder effect in xeroderma pigmentosum group C from north Africa","volume":"130","author":"Soufir","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0115","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0300-9084(91)90121-G","article-title":"Amplification of Epstein-Barr virus-based shuttle vectors by ultraviolet light in human cells","volume":"73","author":"Stary","year":"1991","journal-title":"Biochimie"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0120","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.molcel.2011.06.023","article-title":"The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol \u03b7 in response to oxidative DNA damage in human cells","volume":"43","author":"Zlatanou","year":"2011","journal-title":"Mol. Cell."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0125","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1089\/scd.2013.0067","article-title":"Alternative xeno-free biomaterials derived from human umbilical cord for the self-renewal ex-vivo expansion of mesenchymal stem cells","volume":"22","author":"Kim","year":"2013","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0130","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2119\/2006-00084.DiMaso","article-title":"Subcellular localization of APE1\/Ref-1 in human hepatocellular carcinoma: possible prognostic significance","volume":"13","author":"Di Maso","year":"2007","journal-title":"Mol. Med."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0135","doi-asserted-by":"crossref","first-page":"26701","DOI":"10.1074\/jbc.M503313200","article-title":"Induction of OGG1 gene expression by HIV-1 tat","volume":"280","author":"Imai","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0140","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.mcp.2004.11.004","article-title":"Similar sequence-free amplification of human glyceraldehyde-3-phosphate dehydrogenase for real time RT-PCR applications","volume":"19","author":"Carraro","year":"2005","journal-title":"Mol. Cell. Probes"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0145","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1093\/nar\/gkf469","article-title":"The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function","volume":"30","author":"Khan","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0150","doi-asserted-by":"crossref","first-page":"33926","DOI":"10.1074\/jbc.M109.023879","article-title":"Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells","volume":"284","author":"Frizzell","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0155","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta DeltaC(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0160","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1038\/emboj.2008.210","article-title":"Human DNA polymerase iota protects cells against oxidative stress","volume":"27","author":"Petta","year":"2008","journal-title":"EMBO J."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0165","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0170","doi-asserted-by":"crossref","first-page":"7430","DOI":"10.1128\/MCB.00624-06","article-title":"Redox regulation of human OGG1 activity in response to cellular oxidative stress","volume":"26","author":"Bravard","year":"2006","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0175","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0180","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1093\/nar\/29.6.1285","article-title":"Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step","volume":"29","author":"Vidal","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0185","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0190","doi-asserted-by":"crossref","first-page":"616342","DOI":"10.4061\/2010\/616342","article-title":"True lies: the double life of the nucleotide excision repair factors in transcription and DNA repair","author":"Le May","year":"2010","journal-title":"J. Nucleic Acids"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0195","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.cell.2011.08.038","article-title":"A DNA repair complex functions as an Oct\/Sox2 coactivator in embryonic stem cells","volume":"147","author":"Fong","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0200","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1172\/JCI40087","article-title":"XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas","volume":"1807","author":"Rezvani","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0205","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.bbrc.2007.06.005","article-title":"Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts","volume":"359","author":"Kassam","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0210","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.bbabio.2010.12.006","article-title":"XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species","volume":"1807","author":"Rezvani","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0215","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.dnarep.2013.08.019","article-title":"Slow accumulation of mutations in Xpc\u2212\/\u2212 mice upon induction of oxidative stress","volume":"12","author":"Melis","year":"2013","journal-title":"DNA Repair"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0220","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1093\/nar\/gkm1173","article-title":"Regulation of the human AP-endonuclease (APE1\/Ref-1) expression by the tumor suppressor p53 in response to DNA damage","volume":"36","author":"Zaky","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0225","doi-asserted-by":"crossref","first-page":"11268","DOI":"10.1073\/pnas.200226697","article-title":"Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis","volume":"97","author":"van Oosten","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0230","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1093\/carcin\/22.7.1099","article-title":"DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa Xpc and Csb mice","volume":"22","author":"[46].Wijnhoven","year":"2001","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0235","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.dnarep.2004.06.008","article-title":"Transcription activities at 8-oxoG lesions in DNA","volume":"3","author":"Larsen","year":"2004","journal-title":"DNA Repair"},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0240","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1083\/jcb.201205149","article-title":"Nucleotide excision repair initiating proteins bind to oxidative DNA lesions in vivo","volume":"199","author":"Menoni","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0245","doi-asserted-by":"crossref","first-page":"72","DOI":"10.2741\/3232","article-title":"The molecular Jekyll and Hyde duality of PARP1 in cell death and cell survival","volume":"14","author":"Hassa","year":"2009","journal-title":"Front. Biosci."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0250","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.neuint.2006.11.010","article-title":"Multiple roles for poly(ADP-ribose) polymerase-1 in neurological disease","volume":"50","author":"Kauppinen","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0255","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.freeradbiomed.2009.02.021","article-title":"Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic\/apyrimidinic endonuclease 1\/redox factor-1 haploinsufficient mice","volume":"46","author":"Unnikrishnan","year":"2009","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0260","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/jcp.10159","article-title":"H(2)O(2) induces translocation of APE\/Ref-1 to mitochondria in the Raji B-cell line","volume":"193","author":"Frossi","year":"2002","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0265","doi-asserted-by":"crossref","first-page":"8901","DOI":"10.1074\/jbc.M413022200","article-title":"Contribution of mitochondrial DNA repair to cell resistance from oxidative stress","volume":"280","author":"Grishko","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mrfmmm.2016.01.004_bib0270","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1111\/j.1349-7006.2012.02239.x","article-title":"Human AP endonuclease 1 translocalizes to mitochondria after photodinamic therapy and protects cells from apoptosis","volume":"103","author":"Li","year":"2012","journal-title":"Cancer Sci."}],"container-title":["Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027510716300033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0027510716300033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T14:12:49Z","timestamp":1764684769000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0027510716300033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":54,"alternative-id":["S0027510716300033"],"URL":"https:\/\/doi.org\/10.1016\/j.mrfmmm.2016.01.004","relation":{},"ISSN":["1386-1964"],"issn-type":[{"value":"1386-1964","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"XPC deficiency is related to APE1 and OGG1 expression and function","name":"articletitle","label":"Article Title"},{"value":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mrfmmm.2016.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}