{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:55:02Z","timestamp":1791201302288,"version":"4.2.0"},"reference-count":78,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.mrgentox.2008.01.012","type":"journal-article","created":{"date-parts":[[2008,3,17]],"date-time":"2008-03-17T11:21:49Z","timestamp":1205752909000},"page":"6-13","source":"Crossref","is-referenced-by-count":50,"title":["Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposure"],"prefix":"10.1016","volume":"653","author":[{"given":"Pascal","family":"Pineau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agn\u00e8s","family":"Marchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Battiston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Cordina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Terris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lun-Xiu","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Turlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-You","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Mazzaferro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Dejean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrgentox.2008.01.012_bib1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cld.2004.12.009","article-title":"Epidemiology of hepatocellular carcinoma","volume":"9","author":"Bosch","year":"2005","journal-title":"Clin. Liver Dis."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S1470-2045(04)01508-6","article-title":"Systemic treatment and liver transplantation for hepatocellular carcinoma: two ends of the therapeutic spectrum","volume":"5","author":"Burroughs","year":"2004","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib3","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1053\/j.gastro.2007.04.061","article-title":"Hepatocellular carcinoma: epidemiology and molecular carcinogenesis","volume":"132","author":"El-Serag","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib4","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/sj.bjc.6603649","article-title":"Worldwide variation in the relative importance of hepatitis B and hepatitis C viruses in hepatocellular carcinoma: a systematic review","volume":"96","author":"Raza","year":"2007","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib5","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/mutage\/17.6.471","article-title":"The toxicology of aflatoxins as a basis for public health decisions","volume":"17","author":"Wild","year":"2002","journal-title":"Mutagenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib6","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1016\/j.gastro.2004.09.019","article-title":"Iron, hemochromatosis, and hepatocellular carcinoma","volume":"127","author":"Kowdley","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib7","doi-asserted-by":"crossref","first-page":"9622","DOI":"10.1073\/pnas.89.20.9622","article-title":"Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinoma","volume":"89","author":"Buetow","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib8","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1073\/pnas.91.2.822","article-title":"Genetic heterogeneity of hepatocellular carcinoma","volume":"91","author":"Unsal","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib9","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1038\/sj.onc.1210279","article-title":"TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer","volume":"26","author":"Hussain","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S1535-6108(04)00058-3","article-title":"Focus on hepatocellular carcinoma","volume":"5","author":"Bruix","year":"2004","journal-title":"Cancer Cell"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib11","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/nrc1934","article-title":"Hepatocellular carcinoma pathogenesis: from genes to environment","volume":"6","author":"Farazi","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib12","doi-asserted-by":"crossref","first-page":"3778","DOI":"10.1038\/sj.onc.1209547","article-title":"Genetics of hepatocellular tumors","volume":"25","author":"Laurent-Puig","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib13","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1053\/jlts.2003.50144","article-title":"Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival","volume":"9","author":"Marsh","year":"2003","journal-title":"Liver Transplant."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000048260","article-title":"Prognostic impact of multiple allelic losses on metastatic recurrence in hepatocellular carcinoma after curative resection","volume":"62","author":"Nishida","year":"2002","journal-title":"Oncology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib15","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1001\/archsurg.135.11.1329","article-title":"Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection?","volume":"135","author":"Jeng","year":"2000","journal-title":"Arch. Surg."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib16","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/0140-6736(91)93295-K","article-title":"In utero exposure to aflatoxin in west Africa","volume":"337","author":"Wild","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib17","doi-asserted-by":"crossref","unstructured":"P. Turner, A. Collinson, Y. Cheung, Y. Gong, A. Hall, A. Prentice C., Wild Aflatoxin exposure in utero causes growth faltering in Gambian infants, Int. J. Epidemiol., advance access published on June 18, 2007.","DOI":"10.1093\/ije\/dym122"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib18","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1053\/gast.2001.24798","article-title":"Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis","volume":"120","author":"Laurent-Puig","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib19","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1038\/sj.onc.1209559","article-title":"Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis","volume":"25","author":"Kremsdorf","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib20","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/(SICI)1098-2744(199707)19:3<147::AID-MC1>3.0.CO;2-B","article-title":"The molecular mechanism of aflatoxin B1-induced cancer: is mitotic recombination involved?","volume":"19","author":"Sengstag","year":"1997","journal-title":"Mol. Carcinogen."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib21","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1038\/sj.onc.1207431","article-title":"Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression","volume":"23","author":"Herzog","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib22","doi-asserted-by":"crossref","first-page":"5823","DOI":"10.1128\/MCB.25.14.5823-5833.2005","article-title":"Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage","volume":"25","author":"Guo","year":"2005","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib23","first-page":"1044","article-title":"Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates","volume":"52","author":"Fujimoto","year":"1992","journal-title":"Cancer Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/sj.bjc.6690321","article-title":"Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations","volume":"80","author":"Rashid","year":"1999","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib25","first-page":"4000","article-title":"Genomic aberrations in human hepatocellular carcinomas of differing etiologies","volume":"6","author":"Wong","year":"2000","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib26","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/mc.1041","article-title":"CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1","volume":"31","author":"Devereux","year":"2001","journal-title":"Mol. Carcinogen."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib27","doi-asserted-by":"crossref","first-page":"7971","DOI":"10.1038\/sj.onc.1205919","article-title":"p53 mutation as a source of aberrant beta-catenin accumulation in cancer cells","volume":"21","author":"Cagatay","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib28","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S0959-8049(00)00052-6","article-title":"Trends in mortality from primary liver cancer in Europe","volume":"36","author":"La Vecchia","year":"2000","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib29","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1038\/sj.onc.1209557","article-title":"Southern Europe as an example of interaction between various environmental factors: a systematic review of the epidemiologic evidence","volume":"25","author":"Donato","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib30","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1002\/ijc.22267","article-title":"Food groups and risk of hepatocellular carcinoma: a multicenter case-control study in Italy","volume":"119","author":"Talamini","year":"2006","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib31","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00394-004-0458-2","article-title":"Evaluation of xenobiotics in human milk and ingestion by the newborn\u2014an epidemiological survey in Lombardy (Northern Italy)","volume":"43","author":"Turconi","year":"2004","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib32","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1080\/02652030410001662020","article-title":"Occurrence of mycotoxins and ergosterol in maize harvested over 5 years in Northern Italy","volume":"21","author":"Pietri","year":"2004","journal-title":"Food Addit. Contam."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib33","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/02652030400027995","article-title":"Comparison of contaminant and residue levels in organic and conventional milk and meat products from Northern Italy","volume":"22","author":"Ghidini","year":"2005","journal-title":"Food Addit. Contam."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib34","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/mnfr.200500224","article-title":"Survey of the occurrence of Aflatoxin M1 in ovine milk by HPLC and its confirmation by MS","volume":"50","author":"Bognanno","year":"2006","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib35","first-page":"2303","article-title":"Analysis of the p53 gene in European hepatocellular carcinomas and hepatoblastomas","volume":"8","author":"Debuire","year":"1993","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib36","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/0016-5085(95)90217-1","article-title":"p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation","volume":"108","author":"Bourdon","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib37","first-page":"3","article-title":"A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China","volume":"3","author":"Qian","year":"1994","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib38","series-title":"Theory and Practice of Histological Techniques","author":"Bancroft","year":"2007"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib39","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1038\/sj.onc.1202648","article-title":"Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma","volume":"18","author":"Pineau","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib40","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1086\/315321","article-title":"Effect of TT virus infection on hepatocellular carcinoma development: results of a Euro-Asian survey","volume":"181","author":"Pineau","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib41","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1053\/jhep.2000.9033","article-title":"Hepatocellular carcinoma occurring in nonfibrotic liver: epidemiologic and histopathologic analysis of 80 French cases","volume":"32","author":"Bralet","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib42","doi-asserted-by":"crossref","first-page":"3733","DOI":"10.1038\/sj.onc.1203713","article-title":"Distinct chromosomal abnormality pattern in primary liver cancer of nonB, nonC patients","author":"Marchio","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib43","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bpg.2004.10.004","article-title":"Epidemiology and natural history of hepatocellular carcinoma","volume":"19","author":"McGlynn","year":"2005","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.dld.2007.03.012","article-title":"Genomic Stability prevails in North-African hepatocellular carcinomas","volume":"39","author":"Pineau","year":"2007","journal-title":"Dig. Liver Dis."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib45","doi-asserted-by":"crossref","first-page":"6583","DOI":"10.1038\/sj.onc.1203051","article-title":"Close correlation between \u03b2-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinoma","volume":"18","author":"Terris","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib46","first-page":"89","article-title":"Allelotype study of hepatocellular carcinoma","volume":"51","author":"Fujimori","year":"1991","journal-title":"Cancer Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib47","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.1038\/sj.onc.1201136","article-title":"Comprehensive allelotyping of human hepatocellular carcinoma","volume":"14","author":"Nagai","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib48","first-page":"1986","article-title":"Concerted nonsyntenic allelic losses in hyperplo\u00efd hepatocellular carcinoma as determined by a high-resolution allelotype","volume":"57","author":"Boige","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib49","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/(SICI)1097-0215(19980105)75:1<29::AID-IJC5>3.0.CO;2-3","article-title":"Allelotype analysis of hepatocellular carcinoma","volume":"75","author":"Piao","year":"1998","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib50","doi-asserted-by":"crossref","DOI":"10.1053\/he.2000.6409","article-title":"Comprehensive allelotype study of hepatocellular carcinoma: potential differences in pathways to hepatocellular carcinoma between hepatitis B virus-positive and -negative tumors","volume":"31","author":"Okabe","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib51","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/gcc.10126","article-title":"Comprehensive allelotyping of well-differentiated human hepatocellular carcinoma with semiquantitative determination of chromosomal gain or loss","volume":"35","author":"Nishimura","year":"2002","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib52","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1126\/science.2565047","article-title":"Allelotype of colorectal carcinomas","volume":"244","author":"Vogelstein","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib53","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1383-5742(00)00056-9","article-title":"A review of the genetic and related effects of 1,3-butadiene in rodents and humans","volume":"463","author":"Jackson","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib54","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.mrgentox.2003.12.012","article-title":"In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-phenanthroline using the lacZ transgenic mice","volume":"559","author":"Yamada","year":"2004","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib55","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/sj.cr.7290058","article-title":"Genetic aberration in primary hepatocellular carcinoma: correlation between p53 gene mutation and loss-of-heterozygosity on chromosome 16q21\u2013q23 and 9p21\u2013p23","volume":"10","author":"Wang","year":"2000","journal-title":"Cell Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib56","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/modpathol.3800115","article-title":"Centrosome aberration accompanied with p53 mutation can induce genetic instability in hepatocellular carcinoma","volume":"17","author":"Nakajima","year":"2004","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib57","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S0344-0338(96)80026-4","article-title":"p53 expression in hepatocellular carcinoma in Greece. Correlation with epidemiological and histopathological data","volume":"192","author":"Skopelitou","year":"1996","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib58","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s004280050374","article-title":"Absence of p53 gene mutations in hepatocarcinomas from a Mediterranean area of Spain. A study of 129 archival tumour samples","volume":"434","author":"Boix-Ferrero","year":"1999","journal-title":"Virchows Arch."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib59","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/mpo.10362","article-title":"Genetic alterations in hepatoblastoma and hepatocellular carcinoma associated with familial adenomatous polyposis","volume":"41","author":"Cetta","year":"2003","journal-title":"Med. Pediatr. Oncol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib60","first-page":"1635","article-title":"p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China","volume":"52","author":"Scorsone","year":"1992","journal-title":"Cancer Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib61","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/mutage\/6.1.59","article-title":"Induction of chromosome aberrations and sister chromatid exchange by indirectly acting mutagens in immortal mouse and rat hepatocyte lines","volume":"6","author":"Salassidis","year":"1991","journal-title":"Mutagenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib62","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1093\/carcin\/18.4.633","article-title":"Minisatellite rarrangements are increased in liver tumour induced by transplacental aflatoxin B1 treatment of hepatitis B virus transgenic mice, but not in spontaneously arising tumours","volume":"18","author":"Kaplansky","year":"1997","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib63","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/mc.2940110408","article-title":"DNA recombination induced by aflatoxin B1 activated by cytochrome P450 1A enzymes","volume":"11","author":"Sengstag","year":"1994","journal-title":"Mol. Carcinogen."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib64","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1093\/carcin\/20.11.2143","article-title":"Heterocyclic aromatic amines efficiently induce mitotic recombination in metabolically competent Saccharomyces cerevisiae strains","volume":"20","author":"Paladino","year":"1999","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib65","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1091\/mbc.E04-05-0375","article-title":"Transcriptional response of yeast to aflatoxin B1: recombinational repair involving RAD51 and RAD1","volume":"15","author":"Keller-Seitz","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib66","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1383-5718(97)00170-8","article-title":"Comparative studies of MCL-5 cells and human lymphocytes for detecting indirect-acting clastogens","volume":"412","author":"Yamakage","year":"1998","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib67","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/mutage\/15.1.91","article-title":"Aflatoxin B1-induced mitotic recombination in L5178Y mouse lymphoma cells","volume":"15","author":"Preisler","year":"2000","journal-title":"Mutagenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib68","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/mc.1047","article-title":"Liver carcinogen aflatoxin B1 as an inducer of mitotic recombination in a human cell line","volume":"31","author":"Stettler","year":"2001","journal-title":"Mol. Carcinogen."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib69","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.mrgentox.2005.06.007","article-title":"Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea","volume":"586","author":"Taira","year":"2005","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib70","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.tiv.2005.10.010","article-title":"Anticlastogenic effects of black tea polyphenols theaflavins and thearubigins in human lymphocytes in vitro","volume":"20","author":"Halder","year":"2006","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib71","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.fct.2006.04.010","article-title":"Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1","volume":"44","author":"Peterson","year":"2006","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib72","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/carcin\/24.1.121","article-title":"Perturbations of the Ink4a\/Arf gene locus in aflatoxin B1-induced mouse lung tumors","volume":"24","author":"Tam","year":"2003","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib73","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/S0168-8278(01)00047-2","article-title":"Genome-wide analyses on loss of heterozygosity in hepatocellular carcinoma in Southern China","volume":"34","author":"Li","year":"2001","journal-title":"J. Hepatol."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib74","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/jnci\/94.10.755","article-title":"DNA methylation and environmental exposures in human hepatocellular carcinoma","volume":"94","author":"Shen","year":"2002","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib75","first-page":"699","article-title":"Genetic alterations on chromosomes 3 and 9 of esophageal cancer tissues from China","volume":"12","author":"Wang","year":"1996","journal-title":"Oncogene"},{"issue":"Suppl. 2","key":"10.1016\/j.mrgentox.2008.01.012_bib76","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1016\/S0169-5002(01)00344-0","article-title":"Types and localisation of p53 gene mutations: a report on 332 non-small cell lung cancer patients","volume":"34","author":"Jassem","year":"2001","journal-title":"Lung Cancer"},{"key":"10.1016\/j.mrgentox.2008.01.012_bib77","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1469-1809.2006.00257.x","article-title":"Geographical variations in TP53 mutational spectrum in ovarian carcinomas","volume":"70","author":"Dansonka-Mieszkowska","year":"2006","journal-title":"Ann. Hum. Genet."},{"key":"10.1016\/j.mrgentox.2008.01.012_bib78","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1200\/JCO.2006.06.5961","article-title":"Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors","volume":"24","author":"Calvo","year":"2006","journal-title":"J. Clin. Oncol."}],"container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571808000843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571808000843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T04:33:43Z","timestamp":1557376423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383571808000843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":78,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S1383571808000843"],"URL":"https:\/\/doi.org\/10.1016\/j.mrgentox.2008.01.012","relation":{},"ISSN":["1383-5718"],"issn-type":[{"value":"1383-5718","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}