{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T07:18:20Z","timestamp":1770967100356,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100006055","name":"Consejo de Seguridad Nuclear","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006055","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.mrgentox.2013.03.013","type":"journal-article","created":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T23:15:40Z","timestamp":1374189340000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Suitability of scoring PCC rings and fragments for dose assessment after high-dose exposures to ionizing radiation"],"prefix":"10.1016","volume":"757","author":[{"given":"Roser","family":"Puig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Barrios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f2nica","family":"Pujol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rosa","family":"Caball\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan-Francesc","family":"Barquinero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrgentox.2013.03.013_bib0005","series-title":"Cytogenetic Analysis for Radiation Dose Assessment. A Manual","author":"IAEA","year":"2001"},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0010","article-title":"Review of retrospective dosimetry techniques for external ionising radiation exposures","author":"Ainsbury","year":"2010","journal-title":"Radiat. Prot. Dosim."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0015","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1667\/RR1272.1","article-title":"Interlaboratory comparison of the dicentric chromosome assay for radiation biodosimetry in mass casualty events","volume":"169","author":"Wilkins","year":"2008","journal-title":"Radiat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0020","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1667\/RR2425.1","article-title":"Biological dosimetry intercomparison exercise: an evaluation of triage and routine mode results by robust methods","volume":"175","author":"Di Giorgio","year":"2011","journal-title":"Radiat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0025","unstructured":"K.E. Buckton, Chromosome aberrations in patients treated with X-irradiation for ankylosing spondylitis, in: Alan R. Liss (Ed.), Radiation-Induced Chromosome Damage in Man, New York, 1983, 491\u2013511."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/mutage\/gei063","article-title":"DNA damage checkpoints in mammals","volume":"1","author":"Niida","year":"2006","journal-title":"Mutagenesis"},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0035","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.dnarep.2006.05.011","article-title":"Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability","volume":"5","author":"Jeggo","year":"2006","journal-title":"DNA Repair"},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0040","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF01574257","article-title":"A simple method for premature chromosome condensation induction in primary human and rodent cells using polyethylene glycol","volume":"9","author":"Pantelias","year":"1983","journal-title":"Somat. Cell. Genet."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0045","doi-asserted-by":"crossref","first-page":"140","DOI":"10.2307\/3576452","article-title":"The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry","volume":"99","author":"Pantelias","year":"1984","journal-title":"Radiat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0050","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0027-5107(98)00095-5","article-title":"Kinetics of formation of chromosome aberrations in X-irradiated human lymphocytes, using PCC and FISH","volume":"404","author":"Darroudi","year":"1998","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0055","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1080\/095530096144716","article-title":"Detection and evaluation of chromosomal aberrations induced by high doses of gamma-irradiation using immunogold-silver painting of prematurely condensed chromosomes","volume":"70","author":"Gotoh","year":"1996","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0060","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1383-5718(00)00011-5","volume":"466","author":"Prasanna","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0065","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/jcp.20720","article-title":"Chromosome condensation outside mitosis: mechanisms and new tools","volume":"209","author":"Gotoh","year":"2006","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/09553000500092319","article-title":"A simple biodosimetry method in case of high dose radiation exposure by scoring chromosome number by Giemsa stained drug induced prematurely condensed chromosomes (PCC)","volume":"81","author":"Gotoh","year":"2005","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0075","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1080\/09553000500147667","article-title":"Simple biodosimetry method for cases of high-dose radiation exposure using the radio of the longest\/shortest length of Giemsa-stained drug-induced prematurely condensed chromosomes (PCC)","volume":"81","author":"Gotoh","year":"2005","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0080","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.mrgentox.2010.03.008","article-title":"Biodosimetry for high dose accidental exposures by drug induced premature chromosome condensation (PCC) assay","volume":"699","author":"Balakrishnan","year":"2010","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0085","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1080\/095530099140366","article-title":"Easy biodosimetry for high-dose radiation exposures using drug-induced prematurely condensed chromosomes","volume":"75","author":"Kanda","year":"1999","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0090","first-page":"207","article-title":"PCC-ring induction human lymphocytes exposed to gamma and neutron irradiation","volume":"74","author":"Lamadrid","year":"2007","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0095","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1667\/RR1843.1","article-title":"Premature chromosome condensation (PCC) assay for dose assessment in mass casuality accidents","volume":"173","author":"Lindhom","year":"2010","journal-title":"Radiat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0100","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/0955300042000213673","article-title":"Sister chromatid exchanges in ring chromosomes following X-radiation of human lymphocytes","volume":"80","author":"Kanda","year":"2004","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0105","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/095530098141320","article-title":"A simple method for simultaneous interphase-metaphase chromosome analysis in biodosimetry","volume":"74","author":"Durante","year":"1998","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0110","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0033-7560(75)80001-9","article-title":"Curve fitting by maximum likelihood. Appendix to paper by J.R.K. Savage, Radiation induced chromosomal aberrations in the plant Tradescantia. Dose\u2013response curves","volume":"15","author":"Papworth","year":"1975","journal-title":"Radiat. Bot."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0115","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1080\/095530099139160","article-title":"Comparison of X-ray dose\u2013response curves obtained by chromosome painting using conventional and PAINT nomenclatures","volume":"75","author":"Barquinero","year":"1999","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0120","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1080\/095530097144058","article-title":"Biological dosimetry in simulated in vitro partial irradiations","volume":"71","author":"Barquinero","year":"1997","journal-title":"Int. J. Radiat. Biol."},{"issue":"suppl 2","key":"10.1016\/j.mrgentox.2013.03.013_bib0125","first-page":"195","article-title":"Chromosomal analysis to assess radiation dose","volume":"15","author":"Lloyd","year":"1997","journal-title":"Stem Cells"},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0130","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.7326\/0003-4819-140-12-200406150-00015","article-title":"Medical Management of the acute radiation syndrome: recommendations of the strategic national stockpile radiation working group","volume":"140","author":"Waselenko","year":"2004","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0135","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.molcel.2009.06.031","article-title":"Structure and function of the PP2A-Shugoshin interaction","volume":"35","author":"Xu","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0140","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2307\/3578788","article-title":"Radiation-induced damage, repair and exchange formation in different chromosomes of human fibroblasts determined by fluorescence in situ hybridization","volume":"137","author":"Kovacs","year":"1994","journal-title":"Radiat. Res."},{"key":"10.1016\/j.mrgentox.2013.03.013_bib0145","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.mrfmmm.2009.07.003","article-title":"Cells bearing chromosome aberrations lacking one telomere are selectively blocked at the G2\/M checkpoint","volume":"670","author":"Rodriguez","year":"2009","journal-title":"Mutat. Res."}],"container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571813001873?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571813001873?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T17:42:45Z","timestamp":1563471765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383571813001873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S1383571813001873"],"URL":"https:\/\/doi.org\/10.1016\/j.mrgentox.2013.03.013","relation":{},"ISSN":["1383-5718"],"issn-type":[{"value":"1383-5718","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Suitability of scoring PCC rings and fragments for dose assessment after high-dose exposures to ionizing radiation","name":"articletitle","label":"Article Title"},{"value":"Mutation Research\/Genetic Toxicology and Environmental Mutagenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mrgentox.2013.03.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}