{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:26:30Z","timestamp":1771028790291,"version":"3.50.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.mrgentox.2015.08.002","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T03:31:23Z","timestamp":1438918283000},"page":"71-78","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Low concentrations of caffeine induce asymmetric cell division as observed in vitro by means of the CBMN-assay and iFISH"],"prefix":"10.1016","volume":"793","author":[{"given":"Vasiliki I.","family":"Hatzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Karakosta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Barszczewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioanna","family":"Karachristou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Pantelias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia I.","family":"Terzoudi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrgentox.2015.08.002_bib0005","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s10654-014-9944-x","article-title":"Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis","volume":"29","author":"Greenwood","year":"2014","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0010","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1155\/2013\/791795","article-title":"Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production","volume":"2013","author":"Zeidan-Chulia","year":"2013","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0015","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1038\/bjc.2013.540","article-title":"Intake of coffee, caffeine and other methylxanthines and risk of Type I vs Type II endometrial cancer","volume":"109","author":"Uccella","year":"2013","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0020","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.jpainsymman.2012.10.232","article-title":"Caffeine as an adjuvant therapy to opioids in cancer pain: a randomized, double-blind, placebo-controlled trial","volume":"46","author":"Suh","year":"2013","journal-title":"J. Pain. Symptom Manage"},{"issue":"Suppl 3","key":"10.1016\/j.mrgentox.2015.08.002_bib0025","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3109\/14767058.2010.517704","article-title":"Caffeine impact on neonatal morbidities","volume":"23","author":"Aranda","year":"2010","journal-title":"J. Matern. Fetal. Neonatal. Med."},{"issue":"5","key":"10.1016\/j.mrgentox.2015.08.002_bib0030","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1093\/humrep\/dev063","article-title":"Caffeine and caffeinated beverage consumption and risk of spontaneous abortion","volume":"30","author":"Hahn","year":"2015","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0035","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2174\/1874473708666150113165705","article-title":"Caffeine consumption in children, adolescents and adults","volume":"7","author":"Verster","year":"2015","journal-title":"Curr. Drug Abuse Rev."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0040","first-page":"1","article-title":"Coffee: a selected overview of beneficial or harmful effects on the cardiovascular system?","author":"Whayne Tf","year":"2014","journal-title":"Curr. Vasc. Pharmacol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0045","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1515\/REVEH.1987.7.3-4.279","article-title":"Effects of caffeine on chromosomes in cells of higher eukaryotic organisms","volume":"7","author":"Kihlman","year":"1987","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0050","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0027-5107(74)80036-9","article-title":"Effects of caffeine on the genetic material","volume":"26","author":"Kihlman","year":"1974","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0055","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0027-5107(94)90174-0","article-title":"Caffeine potentiates or protects against radiation-induced DNA and chromosomal damage in human lymphocytes depending on temperature and concentration","volume":"311","author":"Stoilov","year":"1994","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0060","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1753-4887.1978.tb03717.x","article-title":"Caffeine-its identity, dietary sources, intake and biological effects","volume":"36","author":"Graham","year":"1978","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/0265203021000007840","article-title":"Effects of caffeine on human health","volume":"20","author":"Nawrot","year":"2003","journal-title":"Food Addit Contam"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0070","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0027-5107(79)90227-6","article-title":"Effects of caffeine on chromosome aberrations and sister-chromatid exchanges induced by mitomycin C in BrdU-labeled human chromosomes","volume":"62","author":"Shiraishi","year":"1979","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0075","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/BF00291363","article-title":"Effect of caffeine in G2 on X-ray-induced chromosomal aberrations and mitotic inhibition in ataxia telangiectasia fibroblast and lymphoblastoid cells","volume":"67","author":"Hansson","year":"1984","journal-title":"Hum. Genet."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0080","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF00278969","article-title":"The effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro","volume":"54","author":"Natarajan","year":"1980","journal-title":"Hum. Genet."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0085","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1158\/1055-9965.EPI-05-0353","article-title":"Gamma-Radiation-induced chromosomal mutagen sensitivity is associated with breast cancer risk in African\u2013American women: caffeine modulates the outcome of mutagen sensitivity assay","volume":"15","author":"Natarajan","year":"2006","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0090","first-page":"2375","article-title":"The mutagenic action of caffeine in higher organisms","volume":"28","author":"Kuhlmann","year":"1968","journal-title":"Cancer Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0095","series-title":"Caffeine and Chromosomes","author":"Kihlman","year":"1977"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0100","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0165-7992(82)90163-4","article-title":"The effects of post-treatments with caffeine during S and G2 on the frequencies of chromosomal aberrations induced by thiotepa in root tips of Vicia faba and in human lymphocytes in vitro","volume":"104","author":"Kihlman","year":"1982","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0105","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0027-5107(74)80041-2","article-title":"The enhancement by caffeine of the frequencies of chromosomal aberrations induced in plant and animal cells by chemical and physical agents","volume":"26","author":"Kihlman","year":"1974","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0110","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0027-5107(87)90029-7","article-title":"Cytological characterization of chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6 I. Induction of chromosomal aberrations by X-irradiation and its modulation with 3-aminobenzamide and caffeine","volume":"177","author":"Darroudi","year":"1987","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0115","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-7992(85)90106-X","article-title":"Protection and potentiation of radiation clastogenesis by caffeine: nature of possible initial events","volume":"143","author":"Kesavan","year":"1985","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0120","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/0167-4781(89)90138-3","article-title":"Studies on DNA binding of caffeine and derivatives: evidence of intercalation by DNA-unwinding experiments","volume":"1007","author":"Tornaletti","year":"1989","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0125","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s004250000415","article-title":"Replication and G2 checkpoints: their response to caffeine","volume":"212","author":"Pelayo","year":"2001","journal-title":"Planta"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0130","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s10654-014-9956-6","article-title":"Is it dangerous or beneficial to drink coffee? Reflections on a meta-analysis on risk at birth and a population study on risk in late life","volume":"29","author":"Skoog","year":"2014","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0135","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1002\/1097-0142(19880301)61:5<1051::AID-CNCR2820610533>3.0.CO;2-8","article-title":"Caffeine ingestion and breast cancer. A negative correlation","volume":"61","author":"Phelps","year":"1988","journal-title":"Cancer"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0140","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1039\/C4FO00042K","article-title":"Coffee: biochemistry and potential impact on health","volume":"5","author":"Ludwig","year":"2014","journal-title":"Food Funct."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0145","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0360-3016(94)90022-1","article-title":"Caffeine consumption is associated with decreased severe late toxicity after radiation to the pelvis","volume":"30","author":"Stelzer","year":"1994","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0150","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1615\/JEnvironPatholToxicolOncol.v20.i1.70","article-title":"Effect of caffeine on the genotoxic effects of gamma radiation and 4-NQO in diploid yeast","volume":"20","author":"Anjaria","year":"2001","journal-title":"J. Environ. Pathol. Toxicol. Oncol."},{"issue":"Pt 4","key":"10.1016\/j.mrgentox.2015.08.002_bib0155","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1242\/jcs.90.4.591","article-title":"Caffeine induces uncoordinated expression of cell cycle functions after ultraviolet irradiation. Accelerated cycle transit, sister chromatid exchanges and premature chromosome condensation in a transformed Indian muntjac cell line","volume":"90","author":"Musk","year":"1988","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0160","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0027-5107(78)90069-6","article-title":"Post-treatment with caffeine and the induction of gene mutations by ultraviolet irradiation and ethyl methanesulphonate in V-79 Chinese hamster cells in culture","volume":"50","author":"van Zeeland","year":"1978","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0165","first-page":"468","article-title":"Effect of caffeine on the frequency of radiation-induced chromosome aberrations at different stages of the cell cycle","volume":"11","author":"Airapetian","year":"1977","journal-title":"Tsitol. Genet."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0170","first-page":"195","article-title":"Effect of caffeine on radiation induced micronuclei in human lymphocytes","volume":"33","author":"Shukla","year":"2010","journal-title":"Radiat. Prot. Environ."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0175","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1002\/(SICI)1097-0223(199812)18:13<1459::AID-PD514>3.0.CO;2-V","article-title":"Preimplantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16 21, 22","volume":"18","author":"Munne","year":"1998","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0180","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.morpho.2014.02.001","article-title":"Prevalence of aneuploidies in products of spontaneous abortion: interest of FISH and MLPA","volume":"98","author":"Haoud","year":"2014","journal-title":"Morphologie"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0185","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/humrep\/17.2.446","article-title":"Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study","volume":"17","author":"Stephenson","year":"2002","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0190","first-page":"1223","article-title":"G2-checkpoint abrogation in irradiated lymphocytes: a new cytogenetic approach to assess individual radiosensitivity and predisposition to cancer","volume":"35","author":"Terzoudi","year":"2009","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0195","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.radonc.2011.09.021","article-title":"A standardized G2-assay for the prediction of individual radiosensitivity","volume":"101","author":"Pantelias","year":"2011","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0200","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0027-5107(86)90010-2","article-title":"Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation","volume":"161","author":"Fenech","year":"1986","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0205","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0027-5107(00)00065-8","article-title":"The in vitro micronucleus technique","volume":"455","author":"Fenech","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0210","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1383-5718(02)00249-8","article-title":"H.U.M. project, HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures","volume":"534","author":"Fenech","year":"2003","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0215","first-page":"282","article-title":"Die erzeugung von chromatidenbr\u00fcchen durch coffein in leukocytenkulturen des menschen","volume":"3","author":"Ostertag","year":"1967","journal-title":"Humangenetic"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0220","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.dnarep.2006.07.005","article-title":"Caffeine delays replication fork progression and enhances UV-induced homologous recombination in Chinese hamster cell lines","volume":"5","author":"Johansson","year":"2006","journal-title":"DNA Repair"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0225","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.mrgentox.2010.04.006","article-title":"Functional cell-cycle chromatin conformation changes in the presence of DNA damage result into chromatid breaks: a new insight in the formation of radiation-induced chromosomal aberrations based on the direct observation of interphase chromatin","volume":"701","author":"Pantelias","year":"2010","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0230","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.mrfmmm.2010.12.011","article-title":"Chromatin dynamics during cell cycle mediate conversion of DNA damage into chromatid breaks and affect formation of chromosomal aberrations: biological and clinical significance","volume":"711","author":"Terzoudi","year":"2011","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0235","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3109\/09553002.2011.577508","article-title":"A semi-automated micronucleus-centromere assay to assess low-dose radiation exposure in human lymphocytes","volume":"87","author":"Baeyens","year":"2011","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0240","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0165-1218(94)90028-0","article-title":"Detection of hyperdiploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite hydroquinone using multicolor fluorescence in situ hybridization with DNA probes","volume":"322","author":"Eastmond","year":"1994","journal-title":"Mutat. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0245","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/BF00711161","article-title":"Detection of chromosome malsegregation to the daughter nuclei in cytokinesis-blocked transgenic mouse splenocytes","volume":"3","author":"Boei","year":"1995","journal-title":"Chromosome Res."},{"issue":"2","key":"10.1016\/j.mrgentox.2015.08.002_bib0250","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/(SICI)1098-2280(1997)30:2<175::AID-EM10>3.0.CO;2-A","article-title":"Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men","volume":"30","author":"Robbins","year":"1997","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0255","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1111\/j.1349-7006.2008.00862.x","article-title":"Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes","volume":"99","author":"Katsuki","year":"2008","journal-title":"Cancer Sci."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0260","first-page":"43","article-title":"The centromere and aneuploidy: I. Caffeine-induced detachment and fragmentation of kinetochores of mammalian chromosomes","volume":"318","author":"Zinkowski","year":"1989","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0265","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1101\/gad.449407","article-title":"Kinetochore microtubule interaction during S phase in Saccharomyces cerevisiae","volume":"21","author":"Kitamura","year":"2007","journal-title":"Genes Dev."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0270","series-title":"Molecular Biology of the Cell","author":"Alberts","year":"2002"},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0275","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.tcb.2013.01.010","article-title":"Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans","volume":"23","author":"Westermann","year":"2013","journal-title":"Trends Cell. Biol."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0280","first-page":"291","article-title":"Caffeine","volume":"51","author":"IARC","year":"1991","journal-title":"IARC Monogr. Eval. Carcinog Risks Hum."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0285","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1159\/000457676","article-title":"Caffeine disposition in the pregnant rabbit. II. Fetal distribution of caffeine and paraxanthine during chronic maternal caffeine administration","volume":"11","author":"Dorrbecker","year":"1988","journal-title":"Dev. Pharmacol. Ther."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0290","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/cpt1979254447","article-title":"Caffeine metabolism in the newborn","volume":"25","author":"Aldridge","year":"1979","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.mrgentox.2015.08.002_bib0295","first-page":"377","article-title":"Delayed elimination of caffeine by women in the last 2 weeks of pregnancy","volume":"127","author":"Parsons","year":"1982","journal-title":"Can. Med. Assoc. J."}],"container-title":["Mutation Research\/Genetic Toxicology and Environmental Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571815002077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1383571815002077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T01:48:41Z","timestamp":1653011321000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1383571815002077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":59,"alternative-id":["S1383571815002077"],"URL":"https:\/\/doi.org\/10.1016\/j.mrgentox.2015.08.002","relation":{},"ISSN":["1383-5718"],"issn-type":[{"value":"1383-5718","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low concentrations of caffeine induce asymmetric cell division as observed in vitro by means of the CBMN-assay and iFISH","name":"articletitle","label":"Article Title"},{"value":"Mutation Research\/Genetic Toxicology and Environmental Mutagenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mrgentox.2015.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}