{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T10:41:33Z","timestamp":1778668893246,"version":"3.51.4"},"reference-count":48,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1016\/j.mri.2004.09.006","type":"journal-article","created":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T23:29:42Z","timestamp":1103326182000},"page":"1201-1210","source":"Crossref","is-referenced-by-count":58,"title":["Quantification of dynamic contrast-enhanced MR imaging of the knee in children with juvenile rheumatoid arthritis based on pharmacokinetic modeling"],"prefix":"10.1016","volume":"22","author":[{"given":"Dagnachew W.","family":"Workie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard J.","family":"Dardzinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. Brent","family":"Graham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Laor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy A.","family":"Bommer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kendall J.","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mri.2004.09.006_bib1","series-title":"Essentials of anatomy and physiology","author":"Martini","year":"2003"},{"key":"10.1016\/j.mri.2004.09.006_bib2","series-title":"Textbook of pediatric rheumatology","author":"Cassidy","year":"2001"},{"issue":"Suppl. 2","key":"10.1016\/j.mri.2004.09.006_bib3","first-page":"ii94","article-title":"Rheumatoid arthritis in 2003: where are we now with treatment?","volume":"62","author":"Weinblatt","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mri.2004.09.006_bib4","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1006\/cyto.1997.0306","article-title":"Cytokines in juvenile rheumatoid arthritis (JRA)","volume":"10","author":"Mangge","year":"1998","journal-title":"Cytokine"},{"key":"10.1016\/j.mri.2004.09.006_bib5","first-page":"1","article-title":"A prognostic study of juvenile rheumatoid arthritis. Analysis of 544 cases","author":"Laaksonen","year":"1966","journal-title":"Acta Paediatr. Scand."},{"key":"10.1016\/j.mri.2004.09.006_bib6","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1002\/art.1780361007","article-title":"Effects of methotrexate on radiologic progression in juvenile rheumatoid arthritis","volume":"36","author":"Harel","year":"1993","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mri.2004.09.006_bib7","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1056\/NEJM199204163261602","article-title":"Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.\u2013U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group","volume":"326","author":"Giannini","year":"1992","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib8","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1056\/NEJM200003163421103","article-title":"Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group","volume":"342","author":"Lovell","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib9","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/rheumatology\/36.6.683","article-title":"Detection of joint pathology by magnetic resonance imaging in patients with early rheumatoid arthritis","volume":"36","author":"Forslind","year":"1997","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.mri.2004.09.006_bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1148\/radiology.182.1.1727317","article-title":"Juvenile rheumatoid arthritis of the knee: MR evaluation with Gd-DOTA","volume":"182","author":"Herve-Somma","year":"1992","journal-title":"Radiology"},{"key":"10.1016\/j.mri.2004.09.006_bib11","doi-asserted-by":"crossref","first-page":"873","DOI":"10.2214\/ajr.150.4.873","article-title":"MR imaging in juvenile rheumatoid arthritis","volume":"150","author":"Senac","year":"1988","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.mri.2004.09.006_bib12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1148\/radiology.165.1.3628761","article-title":"Juvenile rheumatoid arthritis: assessment with MR imaging","volume":"165","author":"Yulish","year":"1987","journal-title":"Radiology"},{"key":"10.1016\/j.mri.2004.09.006_bib13","first-page":"1151","article-title":"Changes in synovial membrane and joint effusion volumes after intraarticular methylprednisolone. Quantitative assessment of inflammatory and destructive changes in arthritis by MRI","volume":"23","author":"Ostergaard","year":"1996","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mri.2004.09.006_bib14","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1002\/1529-0131(199905)42:5<918::AID-ANR10>3.0.CO;2-2","article-title":"Magnetic resonance imaging-determined synovial membrane volume as a marker of disease activity and a predictor of progressive joint destruction in the wrists of patients with rheumatoid arthritis","volume":"42","author":"Ostergaard","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mri.2004.09.006_bib15","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1148\/radiol.2203000461","article-title":"Knee in early juvenile rheumatoid arthritis: MR imaging findings","volume":"220","author":"Gylys-Morin","year":"2001","journal-title":"Radiology"},{"key":"10.1016\/j.mri.2004.09.006_bib16","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/BF00355334","article-title":"Gadolinium-DTPA in rheumatoid arthritis and related diseases: first results with dynamic magnetic resonance imaging","volume":"18","author":"Reiser","year":"1989","journal-title":"Skeletal Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib17","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3109\/03009749409103060","article-title":"Synovial volume-a marker of disease severity in rheumatoid arthritis? Quantification by MRI","volume":"23","author":"Ostergaard","year":"1994","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.mri.2004.09.006_bib18","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0730-725X(98)00008-3","article-title":"Quantification of synovitis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation","volume":"16","author":"Ostergaard","year":"1998","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib19","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1002\/art.10962","article-title":"Dynamic gadolinium-enhanced magnetic resonance imaging of the wrist in patients with rheumatoid arthritis can discriminate active from inactive disease","volume":"48","author":"Cimmino","year":"2003","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mri.2004.09.006_bib20","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/art.10084","article-title":"Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging","volume":"46","author":"Reece","year":"2002","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mri.2004.09.006_bib21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/mrm.1910160111","article-title":"Quantitation of blood\u2013brain barrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors","volume":"16","author":"Larsson","year":"1990","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/mrm.1910170208","article-title":"Measurement of the blood\u2013brain barrier permeability and leakage space using dynamic MR imaging: 1. Fundamental concepts","volume":"17","author":"Tofts","year":"1991","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib23","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/00004728-199107000-00018","article-title":"Pharmacokinetic parameters in CNS Gd-DTPA enhanced MR imaging","volume":"15","author":"Brix","year":"1991","journal-title":"J. Comput. Assist. Tomogr."},{"key":"10.1016\/j.mri.2004.09.006_bib24","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/1522-2586(200006)11:6<575::AID-JMRI2>3.0.CO;2-1","article-title":"Quantification of endothelial permeability, leakage space, and blood volume in brain tumors using combined T1 and T2* contrast-enhanced dynamic MR imaging","volume":"11","author":"Zhu","year":"2000","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib25","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1076-6332(03)80545-7","article-title":"Correlation of microvascular permeability derived from dynamic contrast-enhanced MR imaging with histologic grade and tumor labeling index: a study in human brain tumors","volume":"8","author":"Roberts","year":"2001","journal-title":"Acad. Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib26","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/mrm.1910330416","article-title":"Quantitative analysis of dynamic Gd-DTPA enhancement in breast tumors using a permeability model","volume":"33","author":"Tofts","year":"1995","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib27","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/mrm.1910330408","article-title":"Pharmacokinetic mapping of the breast: a new method for dynamic MR mammography","volume":"33","author":"Hoffmann","year":"1995","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib28","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/mrm.1910400406","article-title":"Quantification of the extraction fraction for gadopentetate across breast cancer capillaries","volume":"40","author":"Daldrup","year":"1998","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/(SICI)1522-2586(199909)10:3<233::AID-JMRI3>3.0.CO;2-M","article-title":"Multicompartment analysis of gadolinium chelate kinetics: blood\u2013tissue exchange in mammary tumors as monitored by dynamic MR imaging","volume":"10","author":"Port","year":"1999","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib30","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1007\/s003300100944","article-title":"Comparison of pharmacokinetic MRI and [18F] fluorodeoxyglucose PET in the diagnosis of breast cancer: initial experience","volume":"11","author":"Brix","year":"2001","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib31","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1361-8415(97)85011-6","article-title":"Analysis of dynamic MR breast images using a model of contrast enhancement","volume":"1","author":"Hayton","year":"1997","journal-title":"Med. Image Anal."},{"key":"10.1016\/j.mri.2004.09.006_bib32","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/jmri.1880040332","article-title":"In vivo quantification of the unidirectional influx constant for Gd-DTPA diffusion across the myocardial capillaries with MR imaging","volume":"4","author":"Larsson","year":"1994","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib33","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/mrm.1910350513","article-title":"Myocardial perfusion modeling using MRI","volume":"35","author":"Larsson","year":"1996","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib34","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/mrm.1910230205","article-title":"Quantification of myocardial blood flow and extracellular volumes using a bolus injection of Gd-DTPA: kinetic modeling in canine ischemic disease","volume":"23","author":"Diesbourg","year":"1992","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib35","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/mrm.1910400619","article-title":"Capillary transfer constant of Gd-DTPA in the myocardium at rest and during vasodilation assessed by MRI","volume":"40","author":"Fritz-Hansen","year":"1998","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib36","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/jmri.1880070113","article-title":"Modeling tracer kinetics in dynamic Gd-DTPA MR imaging","volume":"7","author":"Tofts","year":"1997","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib37","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0730-725X(02)00504-0","article-title":"In vivo assessment of blood\u2013spinal cord barrier permeability: serial dynamic contrast enhanced MRI of spinal cord injury","volume":"20","author":"Bilgen","year":"2002","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib38","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1002\/mrm.1305","article-title":"A pharmacokinetic model for quantitative evaluation of spinal cord injury with dynamic contrast-enhanced magnetic resonance imaging","volume":"46","author":"Bilgen","year":"2001","journal-title":"Magn. Reson. Med."},{"key":"10.1016\/j.mri.2004.09.006_bib39","article-title":"Dynamic Contrast enhancement patterns in the knee of children with JRA","author":"Dardzinski","year":"2002"},{"key":"10.1016\/j.mri.2004.09.006_bib40","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1522-2586(199909)10:3<223::AID-JMRI2>3.0.CO;2-S","article-title":"Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols","volume":"10","author":"Tofts","year":"1999","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.mri.2004.09.006_bib41","series-title":"Dictionary of the rheumatic diseases","year":"1982"},{"key":"10.1016\/j.mri.2004.09.006_bib42","article-title":"Entropy mapping of articular cartilage","author":"Dardzinski","year":"1999"},{"key":"10.1016\/j.mri.2004.09.006_bib43","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1046\/j.1440-1673.2001.00924.x","article-title":"In vitro study of relationship between signal intensity and gadolinium-DTPA concentration at high magnetic field strength","volume":"45","author":"Shahbazi-Gahrouei","year":"2001","journal-title":"Australas. Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib44","first-page":"379","article-title":"Dynamic MR imaging of the breast","volume":"44","author":"Szabo","year":"2003","journal-title":"Acta Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib45","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/j.1600-0455.2003.00068.x","article-title":"New intravascular contrast agent applied to dynamic contrast enhanced MR imaging of human breast cancer","volume":"44","author":"Rydland","year":"2003","journal-title":"Acta Radiol."},{"key":"10.1016\/j.mri.2004.09.006_bib46","series-title":"Mathematical methods in the physical sciences","author":"Boas","year":"1983"},{"key":"10.1016\/j.mri.2004.09.006_bib47","first-page":"167","article-title":"Pharmacokinetics of GdDTPA\/dimeglumine after intravenous injection into healthy volunteers","volume":"16","author":"Weinmann","year":"1984","journal-title":"Physiol. Chem. Phys. Med. NMR"},{"key":"10.1016\/j.mri.2004.09.006_bib48","series-title":"Magnetic resonance imaging: physical principles and sequence design","author":"Haacke","year":"1999"}],"container-title":["Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0730725X04002711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0730725X04002711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T00:21:10Z","timestamp":1548894070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0730725X04002711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["S0730725X04002711"],"URL":"https:\/\/doi.org\/10.1016\/j.mri.2004.09.006","relation":{},"ISSN":["0730-725X"],"issn-type":[{"value":"0730-725X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}