{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:11:55Z","timestamp":1781759515476,"version":"3.54.5"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Imaging"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.mri.2024.02.016","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T17:15:38Z","timestamp":1709226938000},"page":"49-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Volumetric brain MRI signatures of heart failure with preserved ejection fraction in the setting of dementia"],"prefix":"10.1016","volume":"109","author":[{"given":"Camilo","family":"Bermudez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cailey I.","family":"Kerley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Ramadass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric H.","family":"Farber-Eger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Chen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakmook","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren D.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quinn S.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bennett A.","family":"Landman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.mri.2024.02.016_bb0005","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jalz.2017.02.001","article-title":"2017 Alzheimer\u2019s disease facts and figures","volume":"13","author":"A. s. Association","year":"2017","journal-title":"Alzheimers Dement"},{"issue":"2","key":"10.1016\/j.mri.2024.02.016_bb0010","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/ejhf.631","article-title":"Heart failure and risk of dementia: a Danish nationwide population-based cohort study","volume":"19","author":"Adelborg","year":"2017","journal-title":"Eur J Heart Fail"},{"issue":"9","key":"10.1016\/j.mri.2024.02.016_bb0015","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1001\/archinte.166.9.1003","article-title":"Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study","volume":"166","author":"Qiu","year":"2006","journal-title":"Arch Intern Med"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0020","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.jalz.2014.10.008","article-title":"Vascular contributions to cognitive impairment and dementia including Alzheimer\u2019s disease","volume":"11","author":"Snyder","year":"2015","journal-title":"Alzheimers Dement"},{"issue":"5","key":"10.1016\/j.mri.2024.02.016_bb0025","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.ejheart.2006.11.001","article-title":"Cognitive impairment in heart failure: a systematic review of the literature","volume":"9","author":"Vogels","year":"2007","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"10.1016\/j.mri.2024.02.016_bb0030","first-page":"209","article-title":"Heart failure and cognitive impairment: challenges and opportunities","volume":"2","author":"Heckman","year":"2007","journal-title":"Clin Interv Aging"},{"issue":"4","key":"10.1016\/j.mri.2024.02.016_bb0035","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/ehf2.12192","article-title":"Atrophy of the parahippocampal gyrus is prominent in heart failure patients without dementia","volume":"4","author":"Meguro","year":"2017","journal-title":"ESC Heart Fail"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0040","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/ejhf.275","article-title":"Heart failure and brain failure: two of a kind?","volume":"17","author":"Festen","year":"2015","journal-title":"Eur J Heart Fail"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0045","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1002\/ejhf.222","article-title":"Heart failure and dementia: survival in relation to types of heart failure and different dementia disorders","volume":"17","author":"Cermakova","year":"2015","journal-title":"Eur J Heart Fail"},{"issue":"9","key":"10.1016\/j.mri.2024.02.016_bb0050","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","article-title":"Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"42","author":"Gorelick","year":"2011","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.mri.2024.02.016_bb0055","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1109\/TMI.2016.2553401","article-title":"Guest editorial deep learning in medical imaging: overview and future promise of an exciting new technique","volume":"35","author":"Greenspan","year":"2016","journal-title":"IEEE Trans Med Imaging"},{"issue":"4","key":"10.1016\/j.mri.2024.02.016_bb0060","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1109\/MSP.2010.936730","article-title":"Machine learning in medical imaging","volume":"27","author":"Wernick","year":"2010","journal-title":"IEEE Signal Process Mag"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0065","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1161\/STROKEAHA.111.638437","article-title":"Baseline cardiovascular risk predicts subsequent changes in resting brain function","volume":"43","author":"Beason-Held","year":"2012","journal-title":"Stroke"},{"issue":"13","key":"10.1016\/j.mri.2024.02.016_bb0070","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.009041","article-title":"Increased left ventricular mass index is associated with compromised white matter microstructure among older adults","volume":"7","author":"Moore","year":"2018","journal-title":"J Am Heart Assoc"},{"issue":"8","key":"10.1016\/j.mri.2024.02.016_bb0075","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s12265-015-9644-2","article-title":"A robust e-epidemiology tool in phenotyping heart failure with differentiation for preserved and reduced ejection fraction: the electronic medical records and genomics (eMERGE) network","volume":"8","author":"Bielinski","year":"2015","journal-title":"J Cardiovasc Transl Res"},{"key":"10.1016\/j.mri.2024.02.016_bb0080","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.neuroimage.2019.03.041","article-title":"3D whole brain segmentation using spatially localized atlas network tiles","volume":"194","author":"Huo","year":"2019","journal-title":"NeuroImage"},{"key":"10.1016\/j.mri.2024.02.016_bb0085","series-title":"Medical imaging 2019: Image processing","first-page":"109492V","article-title":"Reproducibility evaluation of SLANT whole brain segmentation across clinical magnetic resonance imaging protocols","volume":"vol. 10949","author":"Xiong","year":"2019"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0090","doi-asserted-by":"crossref","DOI":"10.1117\/1.JMI.7.6.064004","article-title":"Generalizing deep whole-brain segmentation for post-contrast MRI with transfer learning","volume":"7","author":"Bermudez","year":"2020","journal-title":"J Med Imaging"},{"key":"10.1016\/j.mri.2024.02.016_bb0095","series-title":"Medical imaging 2020: Image processing","first-page":"113130L","article-title":"Generalizing deep whole brain segmentation for pediatric and post-contrast MRI with augmented transfer learning","volume":"vol. 11313","author":"Bermudez","year":"2020"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0100","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1006\/nimg.2002.1040","article-title":"Accurate, robust, and automated longitudinal and cross-sectional brain change analysis","volume":"17","author":"Smith","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.mri.2024.02.016_bb0105","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23","author":"Smith","year":"2004","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0110","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00439-013-1355-7","article-title":"A genome-and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects","volume":"133","author":"Shameer","year":"2014","journal-title":"Hum Genet"},{"issue":"20","key":"10.1016\/j.mri.2024.02.016_bb0115","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2014.02.553","article-title":"\u201copposing effects of ABCG5\/8 function on myocardial infarction and gallstone disease,\u201d ed","volume":"63","author":"Hancock-Cerutti","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.mri.2024.02.016_bb0120","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1161\/CIRCULATIONAHA.112.000604","article-title":"Genome-and phenome-wide analysis of cardiac conduction identifies markers of arrhythmia risk","volume":"127","author":"Ritchie","year":"2013","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.mri.2024.02.016_bb0125","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1161\/01.STR.0000024523.82311.77","article-title":"Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease","volume":"33","author":"Suter","year":"2002","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0130","first-page":"1","article-title":"Cerebral perfusion insufficiency and relationships with cognitive deficits in Alzheimer\u2019s disease: a multiparametric neuroimaging study","volume":"8","author":"Huang","year":"2018","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.mri.2024.02.016_bb0135","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s10741-015-9488-5","article-title":"Structural brain alterations in heart failure: a review of the literature and implications for risk of Alzheimer\u2019s disease","volume":"20","author":"Alosco","year":"2015","journal-title":"Heart Fail Rev"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0140","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1552-6569.2008.00293.x","article-title":"Cortical thinning in vascular mild cognitive impairment and vascular dementia of subcortical type","volume":"20","author":"Seo","year":"2010","journal-title":"J Neuroimaging"},{"issue":"1\u20132","key":"10.1016\/j.mri.2024.02.016_bb0145","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jns.2014.04.017","article-title":"The pattern of brain gray matter impairments in patients with subcortical vascular dementia","volume":"341","author":"Liu","year":"2014","journal-title":"J Neurol Sci"},{"issue":"4","key":"10.1016\/j.mri.2024.02.016_bb0150","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.neuroimage.2005.06.066","article-title":"The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT","volume":"28","author":"Hirao","year":"2005","journal-title":"Neuroimage"},{"issue":"1\u20132","key":"10.1016\/j.mri.2024.02.016_bb0155","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jns.2011.04.028","article-title":"Brain axonal and myelin evaluation in heart failure","volume":"307","author":"Kumar","year":"2011","journal-title":"J Neurol Sci"},{"issue":"4","key":"10.1016\/j.mri.2024.02.016_bb0160","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/ana.92","article-title":"Patterns of temporal lobe atrophy in semantic dementia and Alzheimer\u2019s disease","volume":"49","author":"Chan","year":"2001","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1016\/j.mri.2024.02.016_bb0165","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.cardfail.2012.12.001","article-title":"Visual assessment of brain magnetic resonance imaging detects injury to cognitive regulatory sites in patients with heart failure","volume":"19","author":"Pan","year":"2013","journal-title":"J Card Fail"},{"issue":"2","key":"10.1016\/j.mri.2024.02.016_bb0170","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.nbd.2008.10.004","article-title":"Mammillary bodies and fornix fibers are injured in heart failure","volume":"33","author":"Kumar","year":"2009","journal-title":"Neurobiol Dis"},{"issue":"5","key":"10.1016\/j.mri.2024.02.016_bb0175","first-page":"327","article-title":"Diastolic heart failure: a concise review","volume":"5","author":"Aziz","year":"2013","journal-title":"J Clin Med Res"},{"issue":"3","key":"10.1016\/j.mri.2024.02.016_bb0180","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s12265-017-9736-2","article-title":"Deep phenotyping of systemic arterial hemodynamics in HFpEF (part 2): clinical and therapeutic considerations","volume":"10","author":"Chirinos","year":"2017","journal-title":"J Cardiovasc Transl Res"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0185","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.cardfail.2015.09.003","article-title":"Vascular and microvascular endothelial function in heart failure with preserved ejection fraction","volume":"22","author":"Mar\u00e9chaux","year":"2016","journal-title":"J Card Fail"},{"issue":"2","key":"10.1016\/j.mri.2024.02.016_bb0190","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jacc.2017.05.029","article-title":"Arterial stiffening with exercise in patients with heart failure and preserved ejection fraction","volume":"70","author":"Reddy","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.mri.2024.02.016_bb0195","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s12872-017-0490-9","article-title":"Aortic stiffening precedes onset of heart failure with preserved ejection fraction in patients with asymptomatic diastolic dysfunction","volume":"17","author":"Karagodin","year":"2017","journal-title":"BMC Cardiovasc Disord"},{"issue":"9","key":"10.1016\/j.mri.2024.02.016_bb0200","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1161\/STROKEAHA.116.013508","article-title":"Aortic stiffness and the risk of incident mild cognitive impairment and dementia","volume":"47","author":"Pase","year":"2016","journal-title":"Stroke"},{"issue":"18","key":"10.1016\/j.mri.2024.02.016_bb0205","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1161\/CIRCULATIONAHA.118.032410","article-title":"Higher aortic stiffness is related to lower cerebral blood flow and preserved cerebrovascular reactivity in older adults","volume":"138","author":"Jefferson","year":"2018","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.mri.2024.02.016_bb0210","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","article-title":"Vascular contributions to cognitive impairment and dementia","volume":"42","author":"Gorelick","year":"2011","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.mri.2024.02.016_bb0215","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1136\/hrt.2005.068296","article-title":"Non-cardiac comorbidities in chronic heart failure","volume":"93","author":"Lang","year":"2007","journal-title":"Heart"},{"issue":"11","key":"10.1016\/j.mri.2024.02.016_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0225495","article-title":"Discovering novel disease comorbidities using electronic medical records","volume":"14","author":"Chaganti","year":"2019","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.mri.2024.02.016_bb0225","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/S0735-1097(03)00947-1","article-title":"Noncardiac comorbidity increases preventable hospitalizations and mortality among Medicare beneficiaries with chronic heart failure","volume":"42","author":"Braunstein","year":"2003","journal-title":"J Am Coll Cardiol"}],"container-title":["Magnetic Resonance Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0730725X24000481?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0730725X24000481?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T18:07:51Z","timestamp":1715710071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0730725X24000481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":45,"alternative-id":["S0730725X24000481"],"URL":"https:\/\/doi.org\/10.1016\/j.mri.2024.02.016","relation":{},"ISSN":["0730-725X"],"issn-type":[{"value":"0730-725X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Volumetric brain MRI signatures of heart failure with preserved ejection fraction in the setting of dementia","name":"articletitle","label":"Article Title"},{"value":"Magnetic Resonance Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mri.2024.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}