{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:05:36Z","timestamp":1787670336647,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,2,1]],"date-time":"2027-02-01T00:00:00Z","timestamp":1801440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000076","name":"National Science Foundation Directorate for Biological Sciences","doi-asserted-by":"publisher","award":["MCB-2335137"],"award-info":[{"award-number":["MCB-2335137"]}],"id":[{"id":"10.13039\/100000076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance Letters"],"published-print":{"date-parts":[[2027,2]]},"DOI":"10.1016\/j.mrl.2026.200305","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T06:59:55Z","timestamp":1785826795000},"page":"200305","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Using 19F NMR to quantify enthalpy-entropy compensation in protein-protein interactions"],"prefix":"10.1016","volume":"7","author":[{"given":"Thomas W.","family":"Redvanly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6307-542X","authenticated-orcid":false,"given":"Gary J.","family":"Pielak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mrl.2026.200305_bib1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1126\/science.181.4096.223","article-title":"Principles that govern the folding of protein chains","volume":"181","author":"Anfinsen","year":"1973","journal-title":"Science"},{"key":"10.1016\/j.mrl.2026.200305_bib2","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1126\/science.1871600","article-title":"A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G","volume":"253","author":"Gronenborn","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.mrl.2026.200305_bib3","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0022-2836(03)00928-8","article-title":"A protein contortionist: core mutations of GB1 that induce dimerization and domain swapping","volume":"333","author":"Byeon","year":"2003","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.mrl.2026.200305_bib4","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/prot.21831","article-title":"The point mutation A34F causes dimerization of GB1","volume":"71","author":"Jee","year":"2008","journal-title":"Proteins: Struct., Funct., Bioinf."},{"key":"10.1016\/j.mrl.2026.200305_bib5","doi-asserted-by":"crossref","DOI":"10.1002\/pro.70062","article-title":"Crowding beyond excluded volume: a tale of two dimers","volume":"34","author":"Olgenblum","year":"2025","journal-title":"Protein Sci."},{"key":"10.1016\/j.mrl.2026.200305_bib6","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jmr.799","article-title":"Interpretation of the temperature dependence of equilibrium and rate constants","volume":"19","author":"Winzor","year":"2006","journal-title":"J. Mol. Recogn."},{"key":"10.1016\/j.mrl.2026.200305_bib7","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1002\/bip.1970.360091002","article-title":"Enthalpy-entropy compensation and phenomena in water solutions of proteins and small molecules: a ubiquitous property of water","volume":"9","author":"Lumry","year":"1970","journal-title":"Biopolymers"},{"key":"10.1016\/j.mrl.2026.200305_bib8","series-title":"On enthalpy\u2013entropy Compensation Characterizing Processes in Aqueous Solution","author":"Mancini","year":"2025"},{"key":"10.1016\/j.mrl.2026.200305_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/pro.70416","article-title":"Sugar-protein interactions control protein-complex stability in crowded Ficoll and dextran solutions","volume":"35","author":"Redvanly","year":"2026","journal-title":"Protein Sci."},{"key":"10.1016\/j.mrl.2026.200305_bib10","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/261566a0","article-title":"Statistical interpretation of enthalpy-entropy compensation","volume":"261","author":"Krug","year":"1976","journal-title":"Nature"},{"key":"10.1016\/j.mrl.2026.200305_bib11","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/prot.10189","article-title":"Searching for quantitative entropy-enthalpy compensation among protein variants","volume":"49","author":"Beasley","year":"2002","journal-title":"Proteins Struct. Funct. Genet."},{"key":"10.1016\/j.mrl.2026.200305_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/pro.5013","article-title":"Quantitative entropy-enthalpy compensation in intraprotein interactions from model-compound data","volume":"33","author":"Redvanly","year":"2024","journal-title":"Protein Sci."},{"key":"10.1016\/j.mrl.2026.200305_bib13","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1021\/j100562a006","article-title":"Enthalpy-entropy compensation. 1. Some fundamental statistical problems associated with the analysis of van't Hoff and Arrhenius data","volume":"80","author":"Krug","year":"1976","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.mrl.2026.200305_bib14","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1021\/j100562a007","article-title":"Enthalpy-entropy compensation 2. Separation of the chemical from the statistical effect","volume":"80","author":"Krug","year":"1976","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.mrl.2026.200305_bib15","series-title":"The Proteomics Protocols Handbook","first-page":"571","article-title":"Protein identification and analysis tools on the ExPasy server","author":"Gasteiger","year":"2005"},{"key":"10.1016\/j.mrl.2026.200305_bib16","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1021\/ac50048a040","article-title":"Calibration of methanol and ethylene glycol nuclear magnetic resonance thermometers","volume":"51","author":"Raiford","year":"1979","journal-title":"Anal. Chem."},{"key":"10.1016\/j.mrl.2026.200305_bib17","doi-asserted-by":"crossref","first-page":"12705","DOI":"10.1002\/chem.201301657","article-title":"19F NMR spectroscopy as a probe of cytoplasmic viscosity and weak protein interactions in living cells","volume":"19","author":"Ye","year":"2013","journal-title":"Chem. Eur J."},{"key":"10.1016\/j.mrl.2026.200305_bib18","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1021\/acs.biochem.6b01251","article-title":"Cosolute and crowding effects on a side-by-side protein dimer","volume":"56","author":"Guseman","year":"2017","journal-title":"Biochemistry"},{"key":"10.1016\/j.mrl.2026.200305_bib19","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1021\/acs.biochem.1c00780","article-title":"A difference between in vitro and in-cell protein dimer formation","volume":"61","author":"Chu","year":"2022","journal-title":"Biochemistry"},{"key":"10.1016\/j.mrl.2026.200305_bib20","series-title":"Polymer Physics Disentangled: an Introduction for Scientists and Engineers","author":"Dobrynin","year":"2026"},{"key":"10.1016\/j.mrl.2026.200305_bib21","series-title":"Scaling Concepts in Polymer Physics","author":"de Gennes","year":"1979"},{"key":"10.1016\/j.mrl.2026.200305_bib22","series-title":"Colloids and the Depletion Interaction","author":"Lekkerkerker","year":"2011"},{"key":"10.1016\/j.mrl.2026.200305_bib23","series-title":"An Introduction to Error Analysis","author":"Taylor","year":"2022"},{"key":"10.1016\/j.mrl.2026.200305_bib24","doi-asserted-by":"crossref","first-page":"12699","DOI":"10.1073\/pnas.1103382108","article-title":"Separation of preferential interaction and excluded volume effects on DNA duplex and hairpin stability","volume":"108","author":"Knowles","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Magnetic Resonance Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772516226000495?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772516226000495?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T05:05:41Z","timestamp":1787375141000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772516226000495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,2]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,2]]}},"alternative-id":["S2772516226000495"],"URL":"https:\/\/doi.org\/10.1016\/j.mrl.2026.200305","relation":{},"ISSN":["2772-5162"],"issn-type":[{"value":"2772-5162","type":"print"}],"subject":[],"published":{"date-parts":[[2027,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Using 19F NMR to quantify enthalpy-entropy compensation in protein-protein interactions","name":"articletitle","label":"Article Title"},{"value":"Magnetic Resonance Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mrl.2026.200305","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.","name":"copyright","label":"Copyright"}],"article-number":"200305"}}