{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:06:40Z","timestamp":1792631200530,"version":"4.5.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.msard.2017.07.001","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T12:34:41Z","timestamp":1499085281000},"page":"92-94","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["A case of lymphoma in a patient on teriflunomide treatment for relapsing multiple sclerosis"],"prefix":"10.1016","volume":"17","author":[{"given":"Anne","family":"Landais","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabi","family":"Alhendi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandine","family":"Gouverneur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Teron-Aboud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.msard.2017.07.001_bib1","unstructured":"Aubagio SPC, 2016. Summary Product Characteristic. Available at: \u3008http:\/\/www.ema.europa.eu\u3009 (official site of the European Medicines Agency)."},{"issue":"6","key":"10.1016\/j.msard.2017.07.001_bib2","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s40265-014-0212-x","article-title":"Teriflunomide and its mechanism of action in multiple sclerosis","volume":"74","author":"Bar-Or","year":"2014","journal-title":"Drugs"},{"issue":"1","key":"10.1016\/j.msard.2017.07.001_bib3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2165\/00002018-199615010-00004","article-title":"Adverse effects of thyroid hormone preparations and antithyroid drugs","volume":"15","author":"Bartalena","year":"1996","journal-title":"Drug Saf."},{"key":"10.1016\/j.msard.2017.07.001_bib4","doi-asserted-by":"crossref","unstructured":"Bayat A., Jones J., Naina H., 2014. Primary Central Nervous System Lymphoma in Rheumatoid Arthritis Treated with Leflunomide (P7.020), \u3008http:\/\/www.neurology.org\/content\/82\/10_Supplement\/P7.020.short\u3009.","DOI":"10.1212\/WNL.82.10_supplement.P7.020"},{"key":"10.1016\/j.msard.2017.07.001_bib5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/1096-9926(200102)63:2<106::AID-TERA1017>3.0.CO;2-R","article-title":"Teratogen update: reproductive risks of leflunomide (Arava); a pyrimidine synthesis inhibitor: counseling women taking leflunomide before or during pregnancy and men taking leflunomide who are contemplating fathering a child","volume":"63","author":"Brent","year":"2001","journal-title":"Teratology"},{"issue":"9","key":"10.1016\/j.msard.2017.07.001_bib6","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1177\/1352458512436594","article-title":"Teriflunomide multiple sclerosis trial Group. long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years","volume":"18","author":"Confavreux","year":"2012","journal-title":"Mult. Scler."},{"issue":"3","key":"10.1016\/j.msard.2017.07.001_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S1474-4422(13)70308-9","article-title":"Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"13","author":"Confavreux","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.msard.2017.07.001_bib8","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1093\/jnci\/92.15.1240","article-title":"Cancer surveillance series: non-hodgkin's lymphoma incidence by histologic subtype in the United States from 1978 through 1995","volume":"92","author":"Groves","year":"2000","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.msard.2017.07.001_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/jncimonographs\/lgu006","article-title":"Medical history, Lifestyle, family history, and occupational risk factors for follicular lymphoma: the interlymph non-Hodgkin lymphoma subtypes project","volume":"48","author":"Linet","year":"2014","journal-title":"J. Natl. Cancer Inst. Monogr."},{"key":"10.1016\/j.msard.2017.07.001_bib10","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/S1474-4422(14)70191-7","article-title":"Oral teriflunomide for patients with a first clinical episode suggestive of multiple sclerosis (TOPIC): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"13","author":"Miller","year":"2014","journal-title":"Lancet Neurol."},{"issue":"14","key":"10.1016\/j.msard.2017.07.001_bib11","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1056\/NEJMoa1014656","article-title":"TEMSO trial Group. randomized trial of oral teriflunomide for relapsing multiple sclerosis","volume":"365","author":"O'Connor","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.msard.2017.07.001_bib12","unstructured":"Sanofi Genzyme Press release, 2017. April 11 available at: \u3008http:\/\/news.genzyme.com\/press-release\/more-30-presentations-new-investigational-data-sanofi-genzymes-multiple-sclerosis-fran\u3009."},{"key":"10.1016\/j.msard.2017.07.001_bib13","series-title":"US Lymphoid Malignancy Statistics By World Health Organization Subtypes","first-page":"443","volume":"66","author":"Teras","year":"2016"},{"issue":"6","key":"10.1016\/j.msard.2017.07.001_bib14","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1177\/1352458513507821","article-title":"Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial\" TENERE Trial Group","volume":"20","author":"Vermersch","year":"2014","journal-title":"Mult. Scler. J."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034817301517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034817301517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:40:39Z","timestamp":1761900039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034817301517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":14,"alternative-id":["S2211034817301517"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2017.07.001","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A case of lymphoma in a patient on teriflunomide treatment for relapsing multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2017.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}