{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T05:47:29Z","timestamp":1772516849553,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.msard.2017.07.002","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T12:34:02Z","timestamp":1499085242000},"page":"63-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"special_numbering":"C","title":["Pregnancy in Multiple Sclerosis: A Portuguese cohort study"],"prefix":"10.1016","volume":"17","author":[{"given":"Joana","family":"Jesus-Ribeiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas","family":"Correia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana In\u00eas","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas","family":"Marques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f3nia","family":"Batista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmo","family":"Mac\u00e1rio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C\u00e9u","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00edvia","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.msard.2017.07.002_bib1","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00415-004-0495-z","article-title":"Effect of intravenous immunoglobulin treatment on pregnancy and postpartum-related relapses in multiple sclerosis","volume":"251","author":"Achiron","year":"2004","journal-title":"J. Neurol."},{"issue":"5","key":"10.1016\/j.msard.2017.07.002_bib2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1212\/WNL.0b013e3181eb5860","article-title":"Breast-feeding, postpartum and prepregnancy disease activity in multiple sclerosis","volume":"75","author":"Airas","year":"2010","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.msard.2017.07.002_bib3","doi-asserted-by":"crossref","first-page":"e0158978","DOI":"10.1371\/journal.pone.0158978","article-title":"Long term clinical prognostic factors in relapsing-remitting multiple sclerosis: insights from a 10-year observational study","volume":"11","author":"Bsteh","year":"2016","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.msard.2017.07.002_bib4","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1007\/s00415-004-0496-y","article-title":"Intravenous immunoglobulins, pregnancy and multiple sclerosis","volume":"251","author":"Confavreux","year":"2004","journal-title":"J. Neurol."},{"issue":"5","key":"10.1016\/j.msard.2017.07.002_bib5","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1056\/NEJM199807303390501","article-title":"Rate of pregnancy-related relapse in multiple sclerosis. Pregnancy in multiple sclerosis group","volume":"339","author":"Confavreux","year":"1998","journal-title":"New Engl. J. Med."},{"issue":"12","key":"10.1016\/j.msard.2017.07.002_bib6","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1212\/01.wnl.0000188898.02018.95","article-title":"Pregnancy, delivery, and birth outcome in women with multiple sclerosis","volume":"65","author":"Dahl","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2017.07.002_bib7","doi-asserted-by":"crossref","unstructured":"Fabian, M., 2016. Pregnancy in the Setting of Multiple Sclerosis. Continuum 22(3, Multiple Sclerosis and Other Demyelinating Diseases), 837-850.","DOI":"10.1212\/CON.0000000000000328"},{"issue":"4","key":"10.1016\/j.msard.2017.07.002_bib8","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1212\/01.wnl.0000318281.98220.6f","article-title":"Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial","volume":"71","author":"Fazekas","year":"2008","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.msard.2017.07.002_bib9","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.clineuro.2012.04.024","article-title":"The effects of long-term exposure to disease-modifying drugs during pregnancy in multiple sclerosis","volume":"115","author":"Fragoso","year":"2013","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.msard.2017.07.002_bib10","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1471-2377-12-124","article-title":"Pregnancy and fetal outcomes after Glatiramer Acetate exposure in patients with multiple sclerosis: a prospective observational multicentric study","volume":"12","author":"Giannini","year":"2012","journal-title":"BMC Neurol."},{"issue":"Suppl 2","key":"10.1016\/j.msard.2017.07.002_bib11","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1177\/135245850000602S05","article-title":"High dose IVIG in the post partum period for prevention of exacerbations in MS","volume":"6","author":"Haas","year":"2000","journal-title":"Mult. Scler."},{"issue":"Suppl 1","key":"10.1016\/j.msard.2017.07.002_bib12","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1159\/000367640","article-title":"Pregnancy in multiple sclerosis","volume":"72","author":"Hellwig","year":"2014","journal-title":"Eur. Neurol."},{"issue":"10","key":"10.1016\/j.msard.2017.07.002_bib13","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jamaneurol.2015.1806","article-title":"Exclusive breastfeeding and the effect on postpartum multiple sclerosis relapses","volume":"72","author":"Hellwig","year":"2015","journal-title":"JAMA Neurol."},{"issue":"6","key":"10.1016\/j.msard.2017.07.002_bib14","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1177\/1352458513507816","article-title":"Predictors and dynamics of postpartum relapses in women with multiple sclerosis","volume":"20","author":"Hughes","year":"2014","journal-title":"Mult. Scler."},{"issue":"4","key":"10.1016\/j.msard.2017.07.002_bib15","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/1352458511402114","article-title":"Safety first, efficacy second in disease modifying therapies","volume":"17","author":"Hutchinson","year":"2011","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2017.07.002_bib16","unstructured":"INE, 2010. Indicadores Sociais."},{"issue":"1","key":"10.1016\/j.msard.2017.07.002_bib17","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/ana.24682","article-title":"Predictors of long-term disability accrual in relapse-onset multiple sclerosis","volume":"80","author":"Jokubaitis","year":"2016","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.msard.2017.07.002_bib18","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1212\/WNL.50.2.317","article-title":"On the evaluation of disability in multiple sclerosis. 1961","volume":"50","author":"Kurtzke","year":"1998","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/j.msard.2017.07.002_bib19","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1177\/1352458513505161","article-title":"One can prevent post-partum MS relapses by exclusive breast feeding: yes","volume":"19","author":"Langer-Gould","year":"2013","journal-title":"Mult. Scler."},{"issue":"8","key":"10.1016\/j.msard.2017.07.002_bib20","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1001\/archneurol.2009.132","article-title":"Exclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis","volume":"66","author":"Langer-Gould","year":"2009","journal-title":"Arch. Neurol."},{"issue":"11","key":"10.1016\/j.msard.2017.07.002_bib21","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1212\/WNL.0b013e3182698c64","article-title":"Disease-modifying drugs for multiple sclerosis in pregnancy: a systematic review","volume":"79","author":"Lu","year":"2012","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.msard.2017.07.002_bib22","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/135245850100700110","article-title":"Disability and prognosis in multiple sclerosis: demographic and clinical variables important for the ability to walk and awarding of disability pension","volume":"7","author":"Myhr","year":"2001","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2017.07.002_bib23","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/1471-2377-12-165","article-title":"Epidural analgesia and cesarean delivery in multiple sclerosis post-partum relapses: the Italian cohort study","volume":"12","author":"Pasto","year":"2012","journal-title":"BMC Neurol."},{"issue":"2","key":"10.1016\/j.msard.2017.07.002_bib24","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/ana.22366","article-title":"Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria","volume":"69","author":"Polman","year":"2011","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.msard.2017.07.002_bib25","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1212\/WNL.0b013e318224afc9","article-title":"Breastfeeding is not related to postpartum relapses in multiple sclerosis","volume":"77","author":"Portaccio","year":"2011","journal-title":"Neurology"},{"issue":"Pt 7","key":"10.1016\/j.msard.2017.07.002_bib26","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1093\/brain\/awq118","article-title":"The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability","volume":"133","author":"Scalfari","year":"2010","journal-title":"Brain"},{"issue":"20","key":"10.1016\/j.msard.2017.07.002_bib27","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1212\/WNL.0b013e3181c1e44f","article-title":"Impact of multiple sclerosis relapses on progression diminishes with time","volume":"73","author":"Tremlett","year":"2009","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.msard.2017.07.002_bib28","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.clineuro.2005.11.016","article-title":"Pregnancy and multiple sclerosis: the children of PRIMS","volume":"108","author":"Vukusic","year":"2006","journal-title":"Clin. Neurol. Neurosurg."},{"issue":"12","key":"10.1016\/j.msard.2017.07.002_bib29","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1177\/1352458513503054","article-title":"One can prevent post-partum MS relapses by exclusive breast feeding: no","volume":"19","author":"Vukusic","year":"2013","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2017.07.002_bib30","doi-asserted-by":"crossref","unstructured":"Vukusic, S., Hutchinson, M., Hours, M., Moreau, T., Cortinovis-Tourniaire, P., Adeleine, P., Confavreux, C., The Pregnancy In Multiple Sclerosis, G., Pregnancy In Multiple Sclerosis, G., 2004. Pregnancy and multiple sclerosis (the PRIMS study): clinical predictors of post-partum relapse. Brain 127(Pt 6), pp. 1353\u20131360.","DOI":"10.1093\/brain\/awh152"},{"issue":"5","key":"10.1016\/j.msard.2017.07.002_bib31","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/nrneurol.2015.53","article-title":"Multiple sclerosis and pregnancy in the 'treatment era'","volume":"11","author":"Vukusic","year":"2015","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.msard.2017.07.002_bib32","unstructured":"WHO, 1996. Global Data Bank on Breastfeeding - Breastfeeding: The Best Start. Geneva: WHO."},{"key":"10.1016\/j.msard.2017.07.002_bib33","unstructured":"WHO, 2004. ICD-10: International statistical classification of diseases and related health problems, 10th revision, vol. 2, 2nd ed. Geneva: WHO."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034817301529?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034817301529?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:42:41Z","timestamp":1761900161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034817301529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":33,"alternative-id":["S2211034817301529"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2017.07.002","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pregnancy in Multiple Sclerosis: A Portuguese cohort study","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2017.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}