{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T16:12:47Z","timestamp":1769875967934,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.msard.2018.01.026","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T12:37:58Z","timestamp":1517402278000},"page":"194-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Multiple sclerosis in pediatric patients in Slovenia"],"prefix":"10.1016","volume":"20","author":[{"given":"N.","family":"Krajnc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ora\u017eem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Rener-Primec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.J.","family":"Kr\u017ean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.msard.2018.01.026_bib1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0022-3476(87)80454-7","article-title":"Multiple sclerosis in childhood: clinical profile in 125 patients","volume":"111","author":"Duquette","year":"1987","journal-title":"J. Paediatr."},{"key":"10.1016\/j.msard.2018.01.026_bib2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/135245859700300105","article-title":"Multiple sclerosis in childhood: clinical features of 149 cases","volume":"3","author":"Ghezzi","year":"1997","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2018.01.026_bib3","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1600-0404.1992.tb05086.x","article-title":"Early onset MS under the age of 16: clinical and paraclinical features","volume":"86","author":"Sandern","year":"1992","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/j.msard.2018.01.026_bib4","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1177\/1352458508101933","article-title":"Demographics of pediatric-onset multiple sclerosis in a MS center population from the Northeastern United States","volume":"15","author":"Chitnis","year":"2009","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2018.01.026_bib5","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1097\/MOP.0b013e3283402b8a","article-title":"Emerging concepts in pediatric-onset multiple sclerosis and related disorders","volume":"22","author":"Tenembaum","year":"2010","journal-title":"Curr. Opin. Pediatr."},{"issue":"8","key":"10.1016\/j.msard.2018.01.026_bib6","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1093\/aje\/kwi280","article-title":"Familial risk of multiple sclerosis: a nationwide cohort study","volume":"162","author":"Nielsen","year":"2005","journal-title":"Ann. J. Epidemiol."},{"issue":"2","key":"10.1016\/j.msard.2018.01.026_bib7","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/ana.22366","article-title":"Diagnostic criteria for multiple sclerosis: 2010 revision of McDonald criteria","volume":"69","author":"Polman","year":"2011","journal-title":"Ann. Neurol."},{"issue":"10","key":"10.1016\/j.msard.2018.01.026_bib8","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1177\/1352458513484547","article-title":"International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorder: revisions to the 2007 definitions","volume":"19","author":"Krupp","year":"2013","journal-title":"Mult. Scler. J."},{"issue":"1","key":"10.1016\/j.msard.2018.01.026_bib9","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1177\/1352458511430704","article-title":"Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis","volume":"18","author":"Chitnis","year":"2012","journal-title":"Mult. Scler. J."},{"issue":"11","key":"10.1016\/j.msard.2018.01.026_bib10","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1177\/0883073812452784","article-title":"Pediatric multiple sclerosis","volume":"27","author":"Bigi","year":"2012","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.msard.2018.01.026_bib11","first-page":"220","article-title":"IVIG as a safe and well tolerated treatment option in young multiple sclerosis patients","volume":"3\u20134","author":"Krajnc","year":"2005","journal-title":"Eur. J. Paediatr. Neurol."},{"key":"10.1016\/j.msard.2018.01.026_bib12","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1212\/WNL.0b013e31822facdd","article-title":"Incidence of aquired CNS demyelinating syndromes in a multicentric cohort of children","volume":"77","author":"Langer-Gould","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2018.01.026_bib13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1212\/01.wnl.0000339482.84392.bd","article-title":"Incidence of aquired demyelination of the CNS in Canadian children","volume":"72","author":"Banwell","year":"2008","journal-title":"Neurology"},{"issue":"166","key":"10.1016\/j.msard.2018.01.026_bib14","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s00431-006-0249-2","article-title":"Pediatric multiple sclerosis and acute dysemminated encephalomyelitis in Germany: results of nationwide survey","volume":"166","author":"Pohl","year":"2007","journal-title":"Eur. J. Paediatr."},{"key":"10.1016\/j.msard.2018.01.026_bib15","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.braindev.2004.06.005","article-title":"Clinical course and prognosis of 27 patients with childhood onset multiple sclerosis in Japan","volume":"27","author":"Shiraishi","year":"2005","journal-title":"Brain Dev."},{"key":"10.1016\/j.msard.2018.01.026_bib16","first-page":"54","article-title":"Increased relapse rate in pediatric-onset compared with adult-onset multiple sclerosis","volume":"66","author":"Gormann","year":"2009","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.msard.2018.01.026_bib17","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/ene.12327","article-title":"Clinical presentation of pediatric multiple sclerosis before puberty","volume":"21","author":"Huppke","year":"2014","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.msard.2018.01.026_bib18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejpn.2014.12.004","article-title":"Multiple sclerosis in children and adolescents. An important differential diagnosis of acute neurological disease","volume":"19","author":"Sandvig","year":"2015","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"4","key":"10.1016\/j.msard.2018.01.026_bib19","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1001\/archneurol.2010.325","article-title":"Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis","volume":"68","author":"Yeh","year":"2011","journal-title":"Arch. Neurol."},{"issue":"1","key":"10.1016\/j.msard.2018.01.026_bib20","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1177\/0883073812452785","article-title":"The management of pediatric multiple sclerosis","volume":"27","author":"Yeh","year":"2012","journal-title":"J. Child Neurol."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034818300373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034818300373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:43:21Z","timestamp":1761900201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034818300373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":20,"alternative-id":["S2211034818300373"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2018.01.026","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multiple sclerosis in pediatric patients in Slovenia","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2018.01.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}