{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T09:05:56Z","timestamp":1761901556813,"version":"build-2065373602"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"MRI"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.msard.2019.101917","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T16:56:25Z","timestamp":1577206585000},"page":"101917","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Pediatric optic neuritis and anti MOG antibodies: a cohort of Italian patients"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7802-8789","authenticated-orcid":false,"given":"Thea","family":"Giacomini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Foiadelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Annovazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Nosadini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Gastaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3014-3913","authenticated-orcid":false,"given":"Diego","family":"Franciotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Panarese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Capris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Camicione","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Lanteri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"De Grandis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Prato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramona","family":"Cordani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lino","family":"Nobili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Morana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Pistorio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Cellerino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Uccelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Savasta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Margherita","family":"Mancardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.msard.2019.101917_bib0001","doi-asserted-by":"crossref","unstructured":"Baumann, M., Hennes, E., Schanda, K., Karenfort, M., Kornek, B., Seidl, R., Diepold, K., Lauffer, H., Marquardt, I., Strautmanis, J., Syrbe, S., Vieker, S., H\u00f6ftberger, R., Reindl, M., Rost\u00e1sy, K., 2016. Children with multiphasic disseminated encephalomyelitis and antibodies to the myelin oligodendrocyte glycoprotein (MOG): extending the spectrum of MOG antibody positive diseases. 1\u20139. https:\/\/doi.org\/10.1177\/1352458516631038.","DOI":"10.1177\/1352458516631038"},{"key":"10.1016\/j.msard.2019.101917_bib0002","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jnnp-2017-316880","article-title":"Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination","volume":"89","author":"Boesen","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.msard.2019.101917_bib0003","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s11940-011-0159-0","article-title":"Treatment of pediatric optic neuritis","volume":"14","author":"Bonhomme","year":"2012","journal-title":"Curr. Treat. Options Neurol."},{"key":"10.1016\/j.msard.2019.101917_bib0004","first-page":"1","article-title":"Clinical\/scientific notes","volume":"2","author":"Chalmoukou","year":"2015","journal-title":"Neurol. Neuroimmunol. NeuroInflamm."},{"key":"10.1016\/j.msard.2019.101917_bib0005","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.pediatrneurol.2018.03.003","article-title":"Clinical characteristics of pediatric optic neuritis with myelin oligodendrocyte glycoprotein seropositive: a cohort study","volume":"83","author":"Chen","year":"2018","journal-title":"Pediatr. Neurol."},{"key":"10.1016\/j.msard.2019.101917_bib0006","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.msard.2018.10.013","article-title":"Comparing myelin oligodendrocyte glycoprotein antibody (MOG-Ab) and non MOG-Ab associated optic neuritis: Clinical course and treatment outcome","volume":"27","author":"Etemadifar","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2019.101917_bib0007","article-title":"Clinical and MRI phenotype of children with MOG antibodies","author":"Fernandez-Carbonell","year":"2015","journal-title":"Mult. Scler. J"},{"key":"10.1016\/j.msard.2019.101917_bib0008","doi-asserted-by":"crossref","unstructured":"Fryer, J.P., Leavitt, J.A., Lo, A.S.S., Weinshenker, B.G., Mckeon, A., Tillema, J., Lennon, V.A., Tobin, W.O., Keegan, B.M., Lucchinetti, C.F., Kantarci, O.H., Mcclelland, C.M., Lee, M.S., Bennett, J.L., Pelak, V.S., Chen, Y., Vanstavern, G., Adesina, O.O., Eggenberger, E.R., Acierno, M.D., Wingerchuk, D.M., Brazis, P.W., Sagen, J., Pittock, S.J., 2018. Myelin oligodendrocyte glycoprotein antibody\u2013positive optic neuritis: clinical characteristics, radiologic clues, and outcome8\u201315. https:\/\/doi.org\/10.1016\/j.ajo.2018.07.020.","DOI":"10.1016\/j.ajo.2018.07.020"},{"key":"10.1016\/j.msard.2019.101917_bib0009","doi-asserted-by":"crossref","unstructured":"Hacohen, Y., Hemingway, C., Nytrova, P., Woodhall, M., Palace, J., Vincent, A., Lim, M., 2015. Myelin oligodendrocyte glycoprotein antibodies are associated with a non-MS course in children1\u20137. https:\/\/doi.org\/10.1212\/NXI.0000000000000081.","DOI":"10.1212\/NXI.0000000000000081"},{"key":"10.1016\/j.msard.2019.101917_bib0010","first-page":"1","article-title":"MOG encephalomyelitis: international recommendations on diagnosis and antibody testing","author":"Jarius","year":"2018","journal-title":"Nervenarzt"},{"key":"10.1016\/j.msard.2019.101917_bib0011","doi-asserted-by":"crossref","unstructured":"Jurynczyk, M., Messina, S., Woodhall, M.R., Raza, N., Everett, R., Roca-fernandez, A., Tackley, G., Hamid, S., Sheard, A., Reynolds, G., Chandratre, S., Hemingway, C., Jacob, A., Vincent, A., Leite, M.I., Waters, P., Palace, J., 2017. Clinical presentation and prognosis in MOG-antibody disease\u00a0: a UK study3128\u20133138. https:\/\/doi.org\/10.1093\/brain\/awx276.","DOI":"10.1093\/brain\/awx276"},{"key":"10.1016\/j.msard.2019.101917_bib0012","article-title":"Prognostic relevance of MOG antibodies in children with an acquired demyelinating syndrome","author":"Kraus","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2019.101917_bib0013","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1177\/1352458513484547","article-title":"International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions","volume":"19","author":"Krupp","year":"2013","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.msard.2019.101917_bib0014","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-018-1335-x","article-title":"Chronic relapsing inflammatory optic neuropathy (CRION): A manifestation of myelin oligodendrocyte glycoprotein antibodies","volume":"15","author":"Lee","year":"2018","journal-title":"J. Neuroinflamm."},{"key":"10.1016\/j.msard.2019.101917_bib0015","first-page":"1","article-title":"Antibodies to myelin oligodendrocyte glycoprotein in chronic relapsing inflammatory optic neuropathy","author":"Liu","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.msard.2019.101917_bib0016","doi-asserted-by":"crossref","unstructured":"Mol, C.L. De, Wong, Y.Y.M., Pelt, E.D. Van, Wokke, B.H.A., Siepman, T.A.M., 2019. The clinical spectrum and incidence of anti-MOG-associated acquired demyelinating syndromes in children and adults1\u20139. https:\/\/doi.org\/10.1177\/1352458519845112.","DOI":"10.1177\/1352458519845112"},{"key":"10.1016\/j.msard.2019.101917_bib0017","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.msard.2018.11.026","article-title":"Unique characteristics of optical coherence tomography (OCT) results and visual acuity testing in myelin oligodendrocyte glycoprotein (MOG) antibody positive pediatric patients","volume":"28","author":"Narayan","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2019.101917_bib0018","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.spen.2017.08.007","article-title":"The spectrum of inflammatory acquired demyelinating syndromes in children","volume":"24","author":"Neuteboom","year":"2017","journal-title":"Semin. Pediatr. Neurol."},{"key":"10.1016\/j.msard.2019.101917_bib0019","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jnnp-2017-316880","article-title":"Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination","volume":"89","author":"Ramanathan","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.msard.2019.101917_bib0020","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jnnp-2017-316880","article-title":"Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination","volume":"89","author":"Ramanathan","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.msard.2019.101917_bib0021","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1177\/1352458515593406","article-title":"Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis","volume":"22","author":"Ramanathan","year":"2016","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2019.101917_bib0022","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/s41582-018-0112-x","article-title":"Myelin oligodendrocyte glycoprotein antibodies in neurological disease","volume":"15","author":"Reindl","year":"2019","journal-title":"Nat. Rev. Neurol."},{"issue":"n. 2","key":"10.1016\/j.msard.2019.101917_bib0023","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(17)30470-2","article-title":"Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteriaTHOMPSON, A. J. et\u00a0al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria","volume":"17","author":"Thompson","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.msard.2019.101917_bib0024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/NXI.0000000000000356","article-title":"Optical coherence tomography and visual evoked potentials in pediatric MS","volume":"4","author":"Waldman","year":"2017","journal-title":"Neurol. Neuroimmunol. NeuroInflamm."},{"key":"10.1016\/j.msard.2019.101917_bib0025","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ajo.2012.08.010","article-title":"Normative reference ranges for the retinal nerve fiber layer, macula, and retinal layer thicknesses in children","volume":"155","author":"Yanni","year":"2013","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.msard.2019.101917_bib0026","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000002822","article-title":"Pediatric optic neuritis","volume":"87","author":"Yeh","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2019.101917_bib0027","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1136\/bjophthalmol-2017-311177","article-title":"Clinical features of demyelinating optic neuritis with seropositive myelin oligodendrocyte glycoprotein antibody in Chinese patients","volume":"102","author":"Zhao","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.msard.2019.101917_bib0028","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Tan, S., Chung, T., Chan, Y., Xu, Q., Zhao, J., Teng, D., Fu, H., Wei, S., 2018. Clinical features of demyelinating optic neuritis with seropositive myelin oligodendrocyte glycoprotein antibody in Chinese patients1372\u20131377. https:\/\/doi.org\/10.1136\/bjophthalmol-2017-311177.","DOI":"10.1136\/bjophthalmol-2017-311177"}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034819309885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034819309885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:49:33Z","timestamp":1761900573000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034819309885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":28,"alternative-id":["S2211034819309885"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2019.101917","relation":{},"ISSN":["2211-0348"],"issn-type":[{"type":"print","value":"2211-0348"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pediatric optic neuritis and anti MOG antibodies: a cohort of Italian patients","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2019.101917","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101917"}}