{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:36:09Z","timestamp":1790757369932,"version":"4.1.0"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008069","name":"University of California, San Francisco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000890","name":"National Multiple Sclerosis Society","doi-asserted-by":"publisher","award":["TA 3062-A-3"],"award-info":[{"award-number":["TA 3062-A-3"]}],"id":[{"id":"10.13039\/100000890","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.msard.2020.101970","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T19:46:23Z","timestamp":1580931983000},"page":"101970","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Comparison of MS inflammatory activity in women using continuous versus cyclic combined oral contraceptives"],"prefix":"10.1016","volume":"41","author":[{"given":"Chelsea S.","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Krishnakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Rowles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Do","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2034-8800","authenticated-orcid":false,"given":"Riley","family":"Bove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.msard.2020.101970_bib0001","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1600-0404.1999.tb00663.x","article-title":"Correlation between sex hormones and magnetic resonance imaging lesions in multiple sclerosis","volume":"99","author":"Bansil","year":"1999","journal-title":"Acta Neurol. Scand"},{"key":"10.1016\/j.msard.2020.101970_bib0014","first-page":"291","article-title":"Progesterone anti-inflammatory properties in hereditary retinal degeneration","volume":"189","author":"Benlloch-Navarro","year":"2019"},{"key":"10.1016\/j.msard.2020.101970_bib0013","article-title":"Current Contraceptive Status Among Women Aged 15\u201349","author":"Daniels","year":"2018","journal-title":"United States, 2015\u20132017 8"},{"key":"10.1016\/j.msard.2020.101970_bib0002","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.brainres.2014.11.051","article-title":"Prefrontal GABA concentration changes in women-Influence of menstrual cycle phase, hormonal contraceptive use, and correlation with premenstrual symptoms","volume":"1597","author":"De Bondt","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.msard.2020.101970_bib0003","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.brainres.2015.07.045","article-title":"Stability of resting state networks in the female brain during hormonal changes and their relation to premenstrual symptoms","volume":"1624","author":"De Bondt","year":"2015","journal-title":"Brain Res."},{"issue":"7","key":"10.1016\/j.msard.2020.101970_bib0004","article-title":"Continuous or extended cycle vs. cyclic use of combined hormonal contraceptives for contraception","author":"Edelman","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"issue":"5","key":"10.1016\/j.msard.2020.101970_bib0005","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3109\/13625180903137329","article-title":"Symptoms of multiple sclerosis in women in relation to cyclical hormone changes","volume":"14","author":"Holmqvist","year":"2009","journal-title":"Eur. J. Contracept. Reprod. Health Care"},{"issue":"60","key":"10.1016\/j.msard.2020.101970_bib0006","first-page":"1","article-title":"Current contraceptive use in the United States, 2006-2010, and changes in patterns of use since 1995","author":"Jones","year":"2012","journal-title":"Nat. Health Stat. Rep."},{"issue":"6-7","key":"10.1016\/j.msard.2020.101970_bib0007","doi-asserted-by":"crossref","first-page":"A486","DOI":"10.1016\/j.autrev.2011.11.023","article-title":"Immunology and the menstrual cycle","volume":"11","author":"Oertelt-Prigione","year":"2012","journal-title":"Autoimmun. Rev."},{"issue":"4","key":"10.1016\/j.msard.2020.101970_bib0008","doi-asserted-by":"crossref","first-page":"e120","DOI":"10.1212\/NXI.0000000000000120","article-title":"Oral contraceptives combined with interferon beta in multiple sclerosis","volume":"2","author":"Pozzilli","year":"2015","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"issue":"3","key":"10.1016\/j.msard.2020.101970_bib0009","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1212\/WNL.53.3.622","article-title":"MRI in multiple sclerosis during the menstrual cycle: relationship with sex hormone patterns","volume":"53","author":"Pozzilli","year":"1999","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.msard.2020.101970_bib0010","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s10517-018-4318-0","article-title":"Changes in functional activity of neutrophils and monocytes isolated from the peripheral blood of women at different phases of the menstrual cycle","volume":"166","author":"Smirnova","year":"2018","journal-title":"Bull. Exp. Biol. Med."},{"issue":"1","key":"10.1016\/j.msard.2020.101970_bib0011","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0022-510X(97)05396-3","article-title":"Menstrually related worsening of symptoms in multiple sclerosis","volume":"149","author":"Zorgdrager","year":"1997","journal-title":"J. Neurol. Sci."},{"issue":"4","key":"10.1016\/j.msard.2020.101970_bib0012","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000066166","article-title":"The premenstrual period and exacerbations in multiple sclerosis","volume":"48","author":"Zorgdrager","year":"2002","journal-title":"Eur. Neurol."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034820300468?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034820300468?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:27:56Z","timestamp":1778840876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034820300468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":14,"alternative-id":["S2211034820300468"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2020.101970","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of MS inflammatory activity in women using continuous versus cyclic combined oral contraceptives","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2020.101970","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101970"}}