{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:43:12Z","timestamp":1768822992180,"version":"3.49.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100014607","name":"Royal Children's Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014607","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","msard-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.msard.2021.103322","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T08:03:41Z","timestamp":1634112221000},"page":"103322","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Age differences in trajectories of self-rated health of young people with Multiple Sclerosis"],"prefix":"10.1016","volume":"57","author":[{"given":"Nikki","family":"Ow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse","family":"Kuspinar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy E.","family":"Mayo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.msard.2021.103322_bib0001","series-title":"Missing Data","author":"Allison","year":"2001"},{"key":"10.1016\/j.msard.2021.103322_bib0002","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12883-018-1026-3","article-title":"Pediatric multiple sclerosis: a review","volume":"18","author":"Alroughani","year":"2018","journal-title":"BMC Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0003","first-page":"449","article-title":"Maturation of the adolescent brain","volume":"9","author":"Arain","year":"2013","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.msard.2021.103322_bib0004","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1212\/WNL.0000000000001045","article-title":"Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth","volume":"83","author":"Aubert-Broche","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2021.103322_bib0005","doi-asserted-by":"crossref","DOI":"10.1212\/NXI.0000000000000616","article-title":"Contribution of normal aging to brain atrophy in MS","volume":"6","author":"Azevedo","year":"2019","journal-title":"Neurol. Neuroimmunol. Neuroinflamm"},{"key":"10.1016\/j.msard.2021.103322_bib0006","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.msard.2018.07.013","article-title":"The disease burden of Multiple Sclerosis from the individual and population perspective: which symptoms matter most?","volume":"25","author":"Barin","year":"2018","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2021.103322_bib0007","first-page":"271","article-title":"Age-related comparisons of people with multiple sclerosis: demographic, disease, and treatment characteristics","volume":"25","author":"Buchanan","year":"2009","journal-title":"NeuroRehabilitation"},{"key":"10.1016\/j.msard.2021.103322_bib0008","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.dhjo.2018.07.008","article-title":"Young adults\u2019 adjustment to a recent diagnosis of multiple sclerosis: the role of identity satisfaction and self-efficacy","volume":"12","author":"Calandri","year":"2019","journal-title":"Disabil. Health J."},{"key":"10.1016\/j.msard.2021.103322_bib0009","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1016\/j.neurobiolaging.2014.02.008","article-title":"Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging","volume":"35","author":"Callaghan","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.msard.2021.103322_bib0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.alcr.2013.11.002","article-title":"Factors of change and cumulative factors in self-rated health trajectories: a systematic review","volume":"19","author":"Cullati","year":"2014","journal-title":"Adv. Life Course Res."},{"key":"10.1016\/j.msard.2021.103322_bib0011","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/MLR.0b013e318190b716","article-title":"Health care expenditure prediction with a single item, self-rated health measure","volume":"47","author":"DeSalvo","year":"2009","journal-title":"Med. Care"},{"key":"10.1016\/j.msard.2021.103322_bib0012","article-title":"Heterogeneity in multiple sclerosis: scratching the surface of a complex disease","volume":"2011","author":"Disanto","year":"2010","journal-title":"Autoimmune Dis."},{"key":"10.1016\/j.msard.2021.103322_bib0013","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1177\/1352458508088917","article-title":"Self-rated physical health predicts change in disability in multiple sclerosis","volume":"14","author":"Drulovic","year":"2008","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2021.103322_bib0014","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1177\/1352458511431725","article-title":"Relapse severity and recovery in early pediatric multiple sclerosis","volume":"18","author":"Fay","year":"2012","journal-title":"Multiple Sclerosis J."},{"key":"10.1016\/j.msard.2021.103322_bib0015","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.msard.2015.09.002","article-title":"Relapses in multiple sclerosis: relationship to disability","volume":"6","author":"Goodin","year":"2016","journal-title":"Mult. Scler Relat. Disord."},{"key":"10.1016\/j.msard.2021.103322_bib0016","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1001\/archneurol.2008.505","article-title":"Increased relapse rate in pediatric-onset compared with adult-onset multiple sclerosis","volume":"66","author":"Gorman","year":"2009","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0017","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1007\/s11136-019-02280-z","article-title":"Age-specific trends in health-related quality of life among US adults: findings from National Health and Nutrition Examination Survey, 2001-2016","volume":"28","author":"Greaney","year":"2019","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.msard.2021.103322_bib0018","article-title":"Which symptoms contribute the most to patients\u2019 perception of health in multiple sclerosis?","volume":"3","author":"Green","year":"2017","journal-title":"Mult. Scler. J. Exp. Transl. Clin."},{"key":"10.1016\/j.msard.2021.103322_bib0019","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1136\/jnnp-2012-303996","article-title":"Long-term outcome of paediatric-onset multiple sclerosis: a population-based study","volume":"84","author":"Harding","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.msard.2021.103322_bib0020","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3109\/07853890109002089","article-title":"The RAND-36 measure of health-related quality of life","volume":"33","author":"Hays","year":"2001","journal-title":"Ann. Med."},{"key":"10.1016\/j.msard.2021.103322_bib0021","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1037\/0022-006X.74.5.797","article-title":"A meta-analytic review of benefit finding and growth","volume":"74","author":"Helgeson","year":"2006","journal-title":"J. Consult. Clin. Psychol."},{"key":"10.1016\/j.msard.2021.103322_bib0022","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2307\/2955359","article-title":"Self-rated health and mortality: a review of twenty-seven community studies","volume":"38","author":"Idler","year":"1997","journal-title":"J. Health Soc. Behav."},{"key":"10.1016\/j.msard.2021.103322_bib0023","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1177\/0883073819845827","article-title":"Epidemiology of pediatric-onset multiple sclerosis: a systematic review of the literature","volume":"34","author":"Jeong","year":"2019","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0024","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1177\/135245850000600411","article-title":"The significant change for the timed 25-foot walk in the multiple sclerosis functional composite","volume":"6","author":"Kaufman","year":"2000","journal-title":"Multiple Sclerosis J."},{"key":"10.1016\/j.msard.2021.103322_bib0025","first-page":"335","article-title":"How multiple sclerosis symptoms vary by age, sex, and race\/ethnicity","volume":"11","author":"Kister","year":"2021","journal-title":"Neurology: Clin. Practice"},{"key":"10.1016\/j.msard.2021.103322_bib0026","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.3109\/09638281003734334","article-title":"Self-rated health and employment status in patients with multiple sclerosis","volume":"32","author":"Krokavcova","year":"2010","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.msard.2021.103322_bib0027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000136645","article-title":"Historical and clinical perspectives of the expanded disability status scale","volume":"31","author":"Kurtzke","year":"2008","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.msard.2021.103322_bib0028","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1477-7525-11-71","article-title":"Do generic utility measures capture what is important to the quality of life of people with multiple sclerosis?","volume":"11","author":"Kuspinar","year":"2013","journal-title":"Health Qual. Life Outcomes"},{"key":"10.1016\/j.msard.2021.103322_bib0029","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1177\/1352458517723718","article-title":"The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability","volume":"24","author":"LaRocca","year":"2018","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2021.103322_bib0030","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q","article-title":"Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination","volume":"47","author":"Lucchinetti","year":"2000","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0031","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.neuroscience.2015.01.049","article-title":"Aging and large-scale functional networks: white matter integrity, gray matter volume, and functional connectivity in the resting state","volume":"290","author":"Marstaller","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.msard.2021.103322_bib0032","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132254","article-title":"Self-rated health among urban adolescents: the roles of age, gender, and their associated factors","volume":"10","author":"Meireles","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.msard.2021.103322_bib0033","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0895-4356(97)00045-0","article-title":"Self-rated health status as a health measure: the predictive value of self-reported health status on the use of physician services and on mortality in the working-age population","volume":"50","author":"Miilunpalo","year":"1997","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.msard.2021.103322_bib0034","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.clinpsy.121208.131413","article-title":"Group-based trajectory modeling in clinical research","volume":"6","author":"Nagin","year":"2010","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"10.1016\/j.msard.2021.103322_bib0035","series-title":"Group-Based Modeling of Development","author":"Nagin","year":"2005"},{"key":"10.1016\/j.msard.2021.103322_bib0036","doi-asserted-by":"crossref","DOI":"10.1097\/01.MLR.0000062554.74615.4C","article-title":"Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation","volume":"41","author":"Norman","year":"2003","journal-title":"Med. Care"},{"key":"10.1016\/j.msard.2021.103322_bib0037","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1586\/14737167.4.5.581","article-title":"The truly remarkable universality of half a standard deviation: confirmation through another look","volume":"4","author":"Norman","year":"2004","journal-title":"Expert. Rev. Pharmacoecon. Outcomes Res."},{"key":"10.1016\/j.msard.2021.103322_bib0038","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1212\/WNL.55.1.51","article-title":"Quality of life as a predictor for change in disability in MS","volume":"55","author":"Nortvedt","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2021.103322_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2021.102966","article-title":"Longitudinal Analysis of Disability Outcomes among Young People with MS","author":"Ow","year":"2021","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2021.103322_bib0040","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17072413","article-title":"Physical fitness and self-rated health in children and adolescents: cross-sectional and longitudinal study","volume":"17","author":"Padilla-Moledo","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.msard.2021.103322_bib0041","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.msard.2014.06.002","article-title":"Associations between onset age and disability in multiple sclerosis patients studied using MSSS and a progression model","volume":"3","author":"Ramachandran","year":"2014","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2021.103322_bib0042","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1080\/01621459.1995.10476592","article-title":"A reference bayesian test for nested hypotheses and its relationship to the schwarz criterion","volume":"90","author":"RE","year":"1995","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.msard.2021.103322_bib0043","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.neurol.2018.04.003","article-title":"Update on pediatric-onset multiple sclerosis","volume":"174","author":"Ruet","year":"2018","journal-title":"Rev. Neurol. (Paris)"},{"key":"10.1016\/j.msard.2021.103322_bib0044","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1001\/jamaneurol.2013.599","article-title":"Early relapses, onset of progression, and late outcome in multiple sclerosis","volume":"70","author":"Scalfari","year":"2013","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0045","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s11136-014-0804-7","article-title":"Contribution of symptom clusters to multiple sclerosis consequences","volume":"24","author":"Shahrbanian","year":"2015","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.msard.2021.103322_bib0046","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1136\/jech.2005.039883","article-title":"What does self rated health measure? Results from the British Whitehall II and French Gazel cohort studies","volume":"60","author":"Singh-Manoux","year":"2006","journal-title":"J. Epidemiol. Community Health"},{"issue":"S","key":"10.1016\/j.msard.2021.103322_bib0047","first-page":"S225","article-title":"Fatigue in multiple sclerosis is associated with self-perceived health, but less with physical performance","author":"Smedal","year":"2009","journal-title":"Multiple Sclerosis"},{"key":"10.1016\/j.msard.2021.103322_bib0048","doi-asserted-by":"crossref","first-page":"899","DOI":"10.5664\/jcsm.6662","article-title":"Self-reported sleep duration and self-rated health in young adults","volume":"13","author":"\u0160tefan","year":"2017","journal-title":"J. Clin. Sleep Med."},{"key":"10.1016\/j.msard.2021.103322_bib0049","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S1474-4422(18)30498-8","article-title":"A global perspective on the burden of multiple sclerosis","volume":"18","author":"Stenager","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0050","doi-asserted-by":"crossref","DOI":"10.1111\/ene.14191","article-title":"Influence of age at disease onset on future relapses and disability progression in patients with multiple sclerosis on immunomodulatory treatment","author":"von Wyl","year":"2020","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0051","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1111\/ene.14191","article-title":"Influence of age at disease onset on future relapses and disability progression in patients with multiple sclerosis on immunomodulatory treatment","volume":"27","author":"von Wyl","year":"2020","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.msard.2021.103322_bib0052","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","article-title":"A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity","volume":"34","author":"Ware","year":"1996","journal-title":"Med. Care"},{"key":"10.1016\/j.msard.2021.103322_bib0053","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/00031305.2016.1154108","article-title":"The ASA\u2019s statement on p-values: context, process, and purpose","volume":"70","author":"Wasserstein","year":"2016","journal-title":"Am. Stat."},{"key":"10.1016\/j.msard.2021.103322_bib0054","first-page":"1","article-title":"Health-related quality of life surveillance\u2013United States, 1993-2002","volume":"54","author":"Zahran","year":"2005","journal-title":"MMWR Surveill. Summ."},{"key":"10.1016\/j.msard.2021.103322_bib0055","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000505331","article-title":"Interrogation of the multiple sclerosis prodrome using high-dimensional health data","volume":"54","author":"Zhao","year":"2020","journal-title":"Neuroepidemiology"}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034821005897?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034821005897?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T16:33:59Z","timestamp":1735576439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034821005897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":55,"alternative-id":["S2211034821005897"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2021.103322","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age differences in trajectories of self-rated health of young people with Multiple Sclerosis","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2021.103322","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103322"}}