{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:39:45Z","timestamp":1789663185604,"version":"4.0.1"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81401390"],"award-info":[{"award-number":["81401390"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2020CFB848"],"award-info":[{"award-number":["2020CFB848"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.msard.2022.103512","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T05:12:15Z","timestamp":1641791535000},"page":"103512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["MRI features and evolution of autoimmune glial fibrillary acidic protein astrocytopathy: A retrospective cross-sectional and longitudinal study"],"prefix":"10.1016","volume":"58","author":[{"given":"Huiting","family":"Liao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianlan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.msard.2022.103512_bib0001","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/ana.25411","article-title":"Brain and cord imaging features in neuromyelitis optica spectrum disorders","volume":"85","author":"Cacciaguerra","year":"2019","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.msard.2022.103512_bib0002","article-title":"Evaluation of brain and spinal cord lesion distribution criteria at disease onset in distinguishing NMOSD from MS and MOG antibody-associated disorder","author":"Cai","year":"2020","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2022.103512_bib0003","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jneuroim.2018.04.016","article-title":"Autoimmune GFAP astrocytopathy: prospective evaluation of 90 patients in 1year","volume":"321","author":"Dubey","year":"2018","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.msard.2022.103512_bib0004","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1023\/A:1007677003387","article-title":"Glial fibrillary acidic protein: gFAP-thirty-one years (1969-2000)","volume":"25","author":"Eng","year":"2000","journal-title":"Neurochem. Res."},{"issue":"11","key":"10.1016\/j.msard.2022.103512_bib0005","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1001\/jamaneurol.2016.2549","article-title":"Autoimmune glial fibrillary acidic protein astrocytopathy: a novel meningoencephalomyelitis","volume":"73","author":"Fang","year":"2016","journal-title":"JAMA Neurol."},{"issue":"2","key":"10.1016\/j.msard.2022.103512_bib0006","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1002\/ana.24881","article-title":"Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: analysis of 102 patients","volume":"81","author":"Flanagan","year":"2017","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.msard.2022.103512_bib0007","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.msard.2018.12.008","article-title":"Pediatric glial fibrillary acidic protein meningoencephalomyelitis: a case report and review of the literature","volume":"29","author":"Francisco","year":"2019","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"26","key":"10.1016\/j.msard.2022.103512_bib0008","first-page":"1","article-title":"Radial contrast enhancement on brain magnetic resonance imaging diagnostic of primary angiitis of the central nervous system: a case report and review of the literature","volume":"8","author":"Ganta","year":"2014","journal-title":"J. Med. Case Rep."},{"issue":"1","key":"10.1016\/j.msard.2022.103512_bib0009","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/(SICI)1098-1136(200007)31:1<69::AID-GLIA70>3.0.CO;2-W","article-title":"Comparative anatomy of the cerebellar cortex in mice lacking vimentin, GFAP, and both vimentin and GFAP","volume":"31","author":"Gim\u00e9nez","year":"2000","journal-title":"Glia"},{"issue":"14","key":"10.1016\/j.msard.2022.103512_bib0010","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1212\/WNL.0000000000003796","article-title":"DPPX antibody-associated encephalitis: main syndrome and antibody effects","volume":"88","author":"Hara","year":"2017","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.msard.2022.103512_bib0011","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1136\/jnnp-2017-316583","article-title":"Clinical and immunological characteristics of the spectrum of GFAP autoimmunity: a case series of 22 patients","volume":"89","author":"Iorio","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"3","key":"10.1016\/j.msard.2022.103512_bib0012","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/WCO.0000000000000676","article-title":"Autoimmune glial fibrillary acidic protein astrocytopathy","volume":"32","author":"Kunchok","year":"2019","journal-title":"Curr. Opin. Neurol."},{"issue":"22","key":"10.1016\/j.msard.2022.103512_bib0013","doi-asserted-by":"crossref","first-page":"e2076","DOI":"10.1212\/WNL.0000000000008562","article-title":"Teaching NeuroImages: autoimmune glial fibrillary acidic protein meningoencephalomyelitis","volume":"93","author":"Lee","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2022.103512_bib0014","doi-asserted-by":"crossref","DOI":"10.1177\/1756286420909973","article-title":"Autoimmune glial fibrillary acidic protein astrocytopathy with lesions distributed predominantly in the entire spinal cord","volume":"13","author":"Li","year":"2020","journal-title":"Ther. Adv. Neurol. Disord."},{"issue":"1","key":"10.1016\/j.msard.2022.103512_bib0015","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000505730","article-title":"Overlapping clinical syndromes in patients with glial fibrillary acidic protein IgG","volume":"27","author":"Lin","year":"2020","journal-title":"NeuroImmunoModulation"},{"issue":"3","key":"10.1016\/j.msard.2022.103512_bib0016","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/ene.13531","article-title":"Autoimmune glial fibrillary acidic protein astrocytopathy in Chinese patients: a retrospective study","volume":"25","author":"Long","year":"2018","journal-title":"Eur. J. Neurol."},{"issue":"5","key":"10.1016\/j.msard.2022.103512_bib0017","doi-asserted-by":"crossref","first-page":"e481","DOI":"10.1212\/NXI.0000000000000481","article-title":"GFAPalpha IgG-associated encephalitis upon daclizumab treatment of MS","volume":"5","author":"Luessi","year":"2018","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"key":"10.1016\/j.msard.2022.103512_bib0018","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.neuroscience.2013.10.050","article-title":"White matter astrocytes in health and disease","volume":"276","author":"Lundgaard","year":"2014","journal-title":"Neuroscience"},{"issue":"20","key":"10.1016\/j.msard.2022.103512_bib0019","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1212\/WNL.0000000000005534","article-title":"Glial fibrillary acid protein: functions and involvement in disease","volume":"90","author":"McKeon","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2022.103512_bib0020","series-title":"Alexander Disease: A Guide For Patients and Families","author":"Messing","year":"2018"},{"key":"10.1016\/j.msard.2022.103512_bib0021","doi-asserted-by":"crossref","DOI":"10.1177\/1759091420949680","article-title":"GFAP at 50","volume":"12","author":"Messing","year":"2020","journal-title":"ASN Neuro"},{"issue":"3","key":"10.1016\/j.msard.2022.103512_bib0022","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.pneurobio.2011.01.005","article-title":"GFAP in health and disease","volume":"93","author":"Middeldorp","year":"2011","journal-title":"Prog. Neurobiol."},{"issue":"6","key":"10.1016\/j.msard.2022.103512_bib0023","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1023\/A:1006936527746","article-title":"Ultrastructural observations of astrocyte end-feet in the rat central nervous system","volume":"27","author":"NAKAZAWA","year":"1998","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.msard.2022.103512_bib0024","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1146\/annurev-pathol-052016-100218","article-title":"Disorders of astrocytes: alexander disease as a model","volume":"12","author":"Olabarria","year":"2017","journal-title":"Annu. Rev. Pathol."},{"issue":"4","key":"10.1016\/j.msard.2022.103512_bib0025","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/jon.12198","article-title":"Perivascular enhancement in a patient with neuromyelitis optica spectrum disease during an optic neuritis attack","volume":"25","author":"Pekcevik","year":"2015","journal-title":"J. Neuroimaging"},{"issue":"10","key":"10.1016\/j.msard.2022.103512_bib0026","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1212\/WNL.0000000000001907","article-title":"Anti-DPPX encephalitis: pathogenic effects of antibodies on gut and brain neurons","volume":"85","author":"Piepgras","year":"2015","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.msard.2022.103512_bib0027","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/nyas.12794","article-title":"Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later","volume":"1366","author":"Pittock","year":"2016","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.msard.2022.103512_bib0028","first-page":"1","article-title":"Glial fibrillary acidic protein IgG related myelitis characterisation and comparison with aquaporin-4-IgG myelitis","volume":"0","author":"Sechi","year":"2018","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.msard.2022.103512_bib0029","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.3389\/fphar.2019.01114","article-title":"Astrocytes: role and functions in brain pathologies","volume":"10","author":"Siracusa","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.msard.2022.103512_bib0030","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1021\/acschemneuro.8b00304","article-title":"N-Methyl-d-aspartate receptor antibody encephalitis: a concise review of the disorder, diagnosis, and management","volume":"10","author":"Staley","year":"2018","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.msard.2022.103512_bib0031","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1148\/radiol.13130353","article-title":"Quantitative susceptibility mapping of multiple sclerosis lesions at various ages","volume":"271","author":"Weiwei Chen","year":"2014","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.msard.2022.103512_bib0032","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/WNO.0000000000000842","article-title":"Enlarged and enhancing optic nerves in advanced glial fibrillary acidic protein meningoencephalomyelitis","volume":"39","author":"White","year":"2019","journal-title":"J. Neuroophthalmol."},{"issue":"2","key":"10.1016\/j.msard.2022.103512_bib0033","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000479948","article-title":"Treatment of autoimmune glial fibrillary acidic protein astrocytopathy: follow-up in 7 cases","volume":"24","author":"Yang","year":"2017","journal-title":"NeuroImmunoModulation"},{"key":"10.1016\/j.msard.2022.103512_bib0034","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3389\/fneur.2018.00251","article-title":"Overlapping autoimmune syndromes in patients with glial fibrillary acidic protein antibodies","volume":"9","author":"Yang","year":"2018","journal-title":"Front. Neurol."},{"key":"10.1016\/j.msard.2022.103512_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2020.102350","article-title":"Autoimmune glial fibrillary acidic protein astrocytopathy mimics infectious meningitis: two case reports","volume":"45","author":"Yang","year":"2020","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"2","key":"10.1016\/j.msard.2022.103512_bib0036","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/jmri.25144","article-title":"Longitudinal change in magnetic susceptibility of new enhanced multiple sclerosis (MS) lesions measured on serial quantitative susceptibility mapping (QSM)","volume":"44","author":"Zhang","year":"2016","journal-title":"J. Magn. Reson. Imaging"}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221103482200027X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221103482200027X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T09:00:37Z","timestamp":1761901237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221103482200027X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":36,"alternative-id":["S221103482200027X"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2022.103512","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MRI features and evolution of autoimmune glial fibrillary acidic protein astrocytopathy: A retrospective cross-sectional and longitudinal study","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2022.103512","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103512"}}