{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:33:06Z","timestamp":1780050786938,"version":"3.53.1"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100008659","name":"European Committee for Treatment and Research in Multiple Sclerosis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.msard.2025.106586","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T02:50:26Z","timestamp":1749783026000},"page":"106586","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Verona validation of the DAAE score, a tool for estimating risk of clinical disease progression in people with multiple sclerosis"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0219-3518","authenticated-orcid":false,"given":"Tom A.","family":"Fuchs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Ziccardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia R.","family":"Jelgerhuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joep","family":"Killestein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva M.M.","family":"Strijbis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Zivadinov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Weinstock-Guttman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menno M.","family":"Schoonheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.msard.2025.106586_bib0001","doi-asserted-by":"crossref","first-page":"e474","DOI":"10.1002\/hsr2.474","article-title":"Transition to secondary progressive multiple sclerosis: the consequences for patients and healthcare systems, a healthcare professional survey","volume":"5","author":"Caseby","year":"2022","journal-title":"Health Sci. Rep."},{"issue":"1","key":"10.1016\/j.msard.2025.106586_bib0002","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1016\/j.jhep.2004.11.015","article-title":"Assessment of the prognosis of cirrhosis: child\u2013Pugh versus MELD","volume":"42","author":"Durand","year":"2005","journal-title":"J. Hepatol."},{"key":"10.1016\/j.msard.2025.106586_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2024.105755","article-title":"Clinical risk stratification: development and validation of the DAAE score, a tool for estimating patient risk of transition to secondary progressive multiple sclerosis","volume":"89","author":"Fuchs","year":"2024","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"2","key":"10.1016\/j.msard.2025.106586_bib0004","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00415-023-12099-x","article-title":"Disease-modifying treatment, long-term outcomes and transition to progressive multiple sclerosis: data based on the New York State MS Consortium","volume":"271","author":"Jakimovski","year":"2024","journal-title":"J. Neurol."},{"key":"10.1016\/j.msard.2025.106586_bib0005","doi-asserted-by":"crossref","unstructured":"Kurtzke J.F. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). 1983;0(November):1444\u20131453.","DOI":"10.1212\/WNL.33.11.1444"},{"issue":"2","key":"10.1016\/j.msard.2025.106586_bib0006","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/1352458513494958","article-title":"Clinical and magnetic resonance imaging predictors of disease progression in multiple sclerosis: a nine-year follow-up study","volume":"20","author":"Lavorgna","year":"2014","journal-title":"Mult. Scler."},{"issue":"2","key":"10.1016\/j.msard.2025.106586_bib0007","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1378\/chest.09-1584","article-title":"Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach","volume":"137","author":"Lip","year":"2010","journal-title":"Chest"},{"issue":"8","key":"10.1016\/j.msard.2025.106586_bib0008","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1111\/ene.14859","article-title":"A novel prognostic score to assess the risk of progression in relapsing\u2212remitting multiple sclerosis patients","volume":"28","author":"Pisani","year":"2021","journal-title":"Euro J. Neurol."},{"issue":"3","key":"10.1016\/j.msard.2025.106586_bib0009","article-title":"Short-term prediction of secondary progression in a sliding window: a test of a predicting algorithm in a validation cohort","volume":"5","author":"Skoog","year":"2019","journal-title":"Mult. Scler. J. Exp. Transl. Clin."},{"issue":"3","key":"10.1016\/j.msard.2025.106586_bib0010","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/WCO.0000000000000811","article-title":"The window of opportunity for treatment of progressive multiple sclerosis","volume":"33","author":"Sorensen","year":"2020","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.msard.2025.106586_bib0011","doi-asserted-by":"crossref","DOI":"10.1111\/ene.15697","article-title":"Cortical lesions at diagnosis predict long-term cognitive impairment in multiple sclerosis: a 20-year study","author":"Ziccardi","year":"2023","journal-title":"Eur. J. Neurol."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034825003281?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034825003281?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:41:59Z","timestamp":1755650519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034825003281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":11,"alternative-id":["S2211034825003281"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2025.106586","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Verona validation of the DAAE score, a tool for estimating risk of clinical disease progression in people with multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2025.106586","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"106586"}}