{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:23:17Z","timestamp":1785367397311,"version":"3.55.0"},"reference-count":8,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.msard.2026.107023","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:24:02Z","timestamp":1768868642000},"page":"107023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Inter-assay variability in anti\u2013JC virus testing for natalizumab: A Spanish cohort"],"prefix":"10.1016","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9917-8675","authenticated-orcid":false,"given":"Luis Fern\u00e1ndez","family":"Espigares","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia Fern\u00e1ndez","family":"Panadero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda D\u00edaz","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis Casado","family":"Choc\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo Dur\u00e1n","family":"Ferreras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.msard.2026.107023_bib0008","article-title":"Approach to JCV testing with natalizumab biosimilar: a UK consensus statement","volume":"89","author":"Dobson","year":"2025","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2026.107023_bib0004","series-title":"Tyruko (natalizumab)","year":"2023"},{"key":"10.1016\/j.msard.2026.107023_bib0007","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00415-025-13273-z","article-title":"Stratify and ImmunoWELL JCV tests performances in a real-world multiple sclerosis cohort: possible clinical implications of biosimilar Natalizumab use","volume":"272","author":"Guerrieri","year":"2025","journal-title":"J. Neurol."},{"issue":"3","key":"10.1016\/j.msard.2026.107023_bib0002","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1001\/jamaneurol.2022.5007","article-title":"Efficacy and safety of the proposed biosimilar natalizumab (PB006) in patients with relapsing-remitting multiple sclerosis: The Antelope Phase 3 randomized clinical trial","volume":"80","author":"Hemmer","year":"2023","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.msard.2026.107023_bib0001","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S1474-4422(17)30282-X","article-title":"Risk of natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: a retrospective analysis of data from four clinical studies","volume":"16","author":"Ho","year":"2017","journal-title":"Lancet Neurol."},{"issue":"7","key":"10.1016\/j.msard.2026.107023_bib0005","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1177\/13524585251346652","article-title":"A comparison of JC virus assay performance provided with originator and biosimilar natalizumab","volume":"31","author":"Varley","year":"2025","journal-title":"Mult. Scler. J."},{"key":"10.1016\/j.msard.2026.107023_bib0006","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1177\/13524585251322683","article-title":"Beyond the switch to the biosimilar of natalizumab: What is the impact of changing the JCV test?","volume":"31","author":"Vukusic","year":"2025","journal-title":"Mult. Scler."},{"key":"10.1016\/j.msard.2026.107023_bib0003","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1177\/13524585251346658","article-title":"Diagnostic uncertainty in the era of biosimilar natalizumab: The case for harmonizing anti-JCV antibody testing","volume":"31","author":"Ziemssen","year":"2025","journal-title":"Mult. Scler."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034826000593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034826000593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T15:48:06Z","timestamp":1780415286000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034826000593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":8,"alternative-id":["S2211034826000593"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2026.107023","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inter-assay variability in anti\u2013JC virus testing for natalizumab: A Spanish cohort","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2026.107023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107023"}}