{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T08:06:55Z","timestamp":1789373215474,"version":"build-2803163510"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T00:00:00Z","timestamp":1787443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","msard-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Multiple Sclerosis and Related Disorders"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.msard.2026.107875","type":"journal-article","created":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T21:42:21Z","timestamp":1787521341000},"page":"107875","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Walking performance is associated with quality of life and disability in relapsing\u2013remitting multiple sclerosis"],"prefix":"10.1016","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2515-9113","authenticated-orcid":false,"given":"Marko","family":"Luostarinen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M","family":"Portaankorva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pirjo","family":"Urpilainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saara","family":"Takala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Venoj\u00e4rvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.msard.2026.107875_bib0020","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12955-022-01992-0","article-title":"Correlated physical and mental health composite scores for the RAND-36 and RAND-12 health surveys: can we keep them simple?","volume":"20","author":"Andersen","year":"2022","journal-title":"Health Qual. Life Outcomes."},{"issue":"23","key":"10.1016\/j.msard.2026.107875_bib0002","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1080\/09638280310001608591","article-title":"A review about the impact of multiple sclerosis on health-related quality of life","volume":"25","author":"Benito-Le\u00f3n","year":"2003","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.msard.2026.107875_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104966","article-title":"Multiple sclerosis and quality of life: the role of cognitive impairment on quality of life in people with multiple sclerosis","volume":"79","author":"Bergmann","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"15","key":"10.1016\/j.msard.2026.107875_bib0025","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1212\/WNL.0000000000002564","article-title":"Health-related quality of life in multiple sclerosis: direct and indirect effects of comorbidity","volume":"86","author":"Berrigan","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.msard.2026.107875_bib0009","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.msard.2018.01.021","article-title":"Physical activity and disability outcomes in multiple sclerosis: a systematic review (2011-2016)","volume":"20","author":"Charron","year":"2018","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"3","key":"10.1016\/j.msard.2026.107875_bib0022","doi-asserted-by":"crossref","first-page":"6416","DOI":"10.4081\/ni.2016.6416","article-title":"Multiple sclerosis patients valuing their own health status: valuation and psychometric properties of the 15D","volume":"8","author":"Dagklis","year":"2016","journal-title":"Neurol. Int."},{"key":"10.1016\/j.msard.2026.107875_bib0005","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2024.1387658","article-title":"Effects of exercise in people with multiple sclerosis: a systematic review and meta-analysis","volume":"12","author":"Du","year":"2024","journal-title":"Front. Public Health"},{"key":"10.1016\/j.msard.2026.107875_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2025.106412","article-title":"The effects of dual-task training on inflammatory biomarkers, physical performance, fatigue, and quality of life in patients with multiple sclerosis","volume":"99","author":"Farajnia","year":"2025","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2026.107875_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104746","article-title":"Effects of aerobic, resistance, and combined exercise training on health-related quality of life in multiple sclerosis: systematic review and meta-analysis","volume":"75","author":"Flores","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"issue":"11","key":"10.1016\/j.msard.2026.107875_bib0001","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-041249","article-title":"Quality of life in adults with multiple sclerosis: a systematic review","volume":"10","author":"Gil-Gonz\u00e1lez","year":"2020","journal-title":"BMJ Open."},{"issue":"12","key":"10.1016\/j.msard.2026.107875_bib0010","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1177\/1352458520915629","article-title":"Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course","volume":"26","author":"Kalb","year":"2020","journal-title":"Mult. Scler."},{"issue":"2","key":"10.1016\/j.msard.2026.107875_bib0029","first-page":"195","article-title":"Reliability of accelerometer scores for measuring sedentary and physical activity behaviors in persons with multiple sclerosis","volume":"33","author":"Klaren","year":"2016","journal-title":"Adapt Phys Act. Q"},{"issue":"13","key":"10.1016\/j.msard.2026.107875_bib0006","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.3109\/09638288.2015.1077397","article-title":"Physical activity and exercise training in multiple sclerosis: a review and content analysis of qualitative research identifying perceived determinants and consequences","volume":"38","author":"Learmonth","year":"2016","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.msard.2026.107875_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104908","article-title":"Correlation of fatigue with disability and accelerometer-measured daily physical activity in patients with relapsing-remitting MS","volume":"78","author":"Luostarinen","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2026.107875_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104963","article-title":"Accelerometry measures of physical activity and sedentary behavior: associations with cognitive functioning in MS","volume":"79","author":"Manglani","year":"2023","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2026.107875_bib0008","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/1471-2377-14-143","article-title":"Physical activity and associated levels of disability and quality of life in people with multiple sclerosis: a large international survey","volume":"14","author":"Marck","year":"2014","journal-title":"BMC. Neurol."},{"key":"10.1016\/j.msard.2026.107875_bib0018","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1471-2377-14-58","article-title":"Systematic literature review and validity evaluation of the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Functional Composite (MSFC) in patients with multiple sclerosis","volume":"14","author":"Meyer-Moock","year":"2014","journal-title":"BMC. Neurol."},{"issue":"9","key":"10.1016\/j.msard.2026.107875_bib0028","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1001\/archneur.57.9.1319","article-title":"Clinical significance of the multiple sclerosis functional composite: relationship to patient-reported quality of life","volume":"57","author":"Miller","year":"2000","journal-title":"Arch. Neurol."},{"issue":"1","key":"10.1016\/j.msard.2026.107875_bib0007","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/13548500802241902","article-title":"Physical activity and quality of life in multiple sclerosis: intermediary roles of disability, fatigue, mood, pain, self-efficacy and social support","volume":"14","author":"Motl","year":"2009","journal-title":"Psychol. Health Med."},{"key":"10.1016\/j.msard.2026.107875_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2022.103833","article-title":"Moderate-to-vigorous physical activity is associated with processing speed, but not learning and memory, in cognitively impaired persons with multiple sclerosis","volume":"63","author":"Motl","year":"2022","journal-title":"Mult. Scler. Relat. Disord."},{"key":"10.1016\/j.msard.2026.107875_bib0016","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.apnr.2016.09.001","article-title":"The interaction of fatigue, physical activity, and health-related quality of life in adults with multiple sclerosis (MS) and cardiovascular disease (CVD)","volume":"33","author":"Newland","year":"2017","journal-title":"Appl. Nurs. Res."},{"issue":"2","key":"10.1016\/j.msard.2026.107875_bib0026","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s00415-022-11453-9","article-title":"Health-related quality of life in Japanese patients with multiple sclerosis","volume":"270","author":"Niino","year":"2023","journal-title":"J. Neurol."},{"issue":"10","key":"10.1016\/j.msard.2026.107875_bib0019","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1097\/00005650-200010000-00006","article-title":"Performance of the SF-36, SF-12, and RAND-36 summary scales in a multiple sclerosis population","volume":"38","author":"Nortvedt","year":"2000","journal-title":"Med. Care"},{"issue":"1-2","key":"10.1016\/j.msard.2026.107875_bib0027","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jns.2003.09.015","article-title":"Correlations between multiple sclerosis functional composite, expanded disability status scale and health-related quality of life during and after treatment of relapses in patients with multiple sclerosis","volume":"218","author":"Ozakbas","year":"2004","journal-title":"J. Neurol. Sci."},{"issue":"9","key":"10.1016\/j.msard.2026.107875_bib0011","first-page":"864","article-title":"Impact of fatigue on quality of life in adults with multiple sclerosis","volume":"40","author":"Pi\u00f1ar-Morales","year":"2025","journal-title":"Neurol. (Engl Ed)"},{"issue":"3","key":"10.1016\/j.msard.2026.107875_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.rehab.2021.101578","article-title":"The type of exercise most beneficial for quality of life in people with multiple sclerosis: a network meta-analysis","volume":"65","author":"Reina-Guti\u00e9rrez","year":"2022","journal-title":"Ann. Phys. Rehabil. Med."},{"key":"10.1016\/j.msard.2026.107875_bib0003","doi-asserted-by":"crossref","DOI":"10.4178\/epih.e2017008","article-title":"The impact of disease characteristics on multiple sclerosis patients' quality of life","volume":"39","author":"Rezapour","year":"2017","journal-title":"Epidemiol. Health"},{"issue":"5","key":"10.1016\/j.msard.2026.107875_bib0021","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3109\/07853890109002086","article-title":"The 15D instrument of health-related quality of life: properties and applications","volume":"33","author":"Sintonen","year":"2001","journal-title":"Ann. Med."},{"key":"10.1016\/j.msard.2026.107875_bib0004","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1477-7525-8-55","article-title":"Disability status and quality of life in multiple sclerosis: nonlinearity of the Expanded Disability Status Scale (EDSS)","volume":"8","author":"Twork","year":"2010","journal-title":"Health Qual. Life Outcomes."}],"container-title":["Multiple Sclerosis and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034826009107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211034826009107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T07:06:28Z","timestamp":1789369588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211034826009107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":29,"alternative-id":["S2211034826009107"],"URL":"https:\/\/doi.org\/10.1016\/j.msard.2026.107875","relation":{},"ISSN":["2211-0348"],"issn-type":[{"value":"2211-0348","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Walking performance is associated with quality of life and disability in relapsing\u2013remitting multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Multiple Sclerosis and Related Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msard.2026.107875","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107875"}}