{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T10:22:15Z","timestamp":1788603735701,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Science and Engineering: C"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.msec.2018.05.020","type":"journal-article","created":{"date-parts":[[2018,5,5]],"date-time":"2018-05-05T11:58:27Z","timestamp":1525521507000},"page":"146-152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["Effect of biogenic silver nanocubes on matrix metalloproteinases 2 and 9 expressions in hyperglycemic skin injury and its impact in early wound healing in streptozotocin-induced diabetic mice"],"prefix":"10.1016","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4912-1279","authenticated-orcid":false,"given":"Natarajan","family":"Krishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8424-1084","authenticated-orcid":false,"given":"Balasubramanian","family":"Velramar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balamurugan","family":"Ramatchandirin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Chelliah","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivas","family":"Duraisamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-8707","authenticated-orcid":false,"given":"Rajesh","family":"Pandiyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh Kannan","family":"Velu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.msec.2018.05.020_bb0005","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejphar.2015.06.029","article-title":"Deferoxamine modulates cytokines and growth factors to accelerate cutaneous wound healing in diabetic rats","volume":"764","author":"Mahendra","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.msec.2018.05.020_bb0010","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1007\/s11033-012-2223-6","article-title":"Soft tissue fibroblasts from well healing and chronic human wounds show different rates of myofibroblasts in vitro","volume":"40","author":"Schwarz","year":"2013","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.msec.2018.05.020_bb0015","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1152\/physiolgenomics.00157.2010","article-title":"MicroRNAs in skin and wound healing","volume":"43","author":"Banerjee","year":"2011","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.msec.2018.05.020_bb0020","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s10456-013-9375-4","article-title":"Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF","volume":"17","author":"Schgoer","year":"2014","journal-title":"Angiogenesis"},{"key":"10.1016\/j.msec.2018.05.020_bb0025","doi-asserted-by":"crossref","first-page":"6377","DOI":"10.1016\/j.biomaterials.2013.05.005","article-title":"A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing","volume":"34","author":"Gong","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.msec.2018.05.020_bb0030","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s12272-014-0368-7","article-title":"Wound healing efficacy of a chitosan-based film-forming gel containing tyrothricin in various rat wound models","volume":"38","author":"Kim","year":"2014","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0035","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejphar.2014.02.033","article-title":"Chitosan-based copper nanocomposite accelerates healing in excision wound model in rats","volume":"731","author":"Gopal","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.msec.2018.05.020_bb0040","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ejphar.2013.04.042","article-title":"Topically applied substance P enhanced healing of open excision wound in rats","volume":"715","author":"Kant","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.msec.2018.05.020_bb0045","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.jdiacomp.2012.05.015","article-title":"Epigenetic mechanisms in the pathogenesis of diabetic foot ulcers","volume":"26","author":"Rafehi","year":"2012","journal-title":"J. Diabetes Complicat."},{"key":"10.1016\/j.msec.2018.05.020_bb0050","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1080\/00015458.2014.11680970","article-title":"Managing diabetic foot infections: a review of the new guidelines","volume":"114","author":"Gariani","year":"2014","journal-title":"Acta Chir. Belg."},{"key":"10.1016\/j.msec.2018.05.020_bb0055","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1016\/j.biomaterials.2008.03.029","article-title":"The inhibition of matrix metalloproteinase activity in chronic wounds by a polyacrylate superabsorber","volume":"29","author":"Eming","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.msec.2018.05.020_bb0060","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s00403-013-1385-y","article-title":"Fir honeydew honey flavonoids inhibit TNF-a-induced MMP-9 expression in human keratinocytes: a new action of honey in wound healing","volume":"305","author":"Majtan","year":"2013","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0065","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00403-009-1011-1","article-title":"Protease and pro-inXammatory cytokine concentrations are elevated in chronic compared to acute wounds and can be modulated by collagen type I in vitro","volume":"302","author":"Wiegand","year":"2010","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0070","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2337\/dc08-0763","article-title":"Increased matrix metalloproteinase-9 predicts poor wound healing in diabetic foot ulcers","volume":"3","author":"Liu","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.msec.2018.05.020_bb0075","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2337\/dc07-1304","article-title":"Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model","volume":"31","author":"Brandner","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.msec.2018.05.020_bb0080","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.intimp.2014.03.009","article-title":"Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats","volume":"20","author":"Kant","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.msec.2018.05.020_bb0085","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s13346-016-0322-y","article-title":"Wound healing applications of sericin\/chitosan-capped silver nanoparticles incorporated hydrogel","volume":"7","author":"Verma","year":"2017","journal-title":"Drug Deliv. Transl. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0090","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1007\/BF02980032","article-title":"Effect of topically applied silver sulfadiazine on fibroblast cell proliferation and biomechanical properties of the wound","volume":"26","author":"Cho Lee","year":"2003","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0095","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1016\/j.biomaterials.2004.11.041","article-title":"Reversal of silver sulfadiazine-impaired wound healing by epidermal growth factor","volume":"26","author":"Cho Lee","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.msec.2018.05.020_bb0100","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1002\/cmdc.200900049","article-title":"Further evidence of the anti-inflammatory effects of silver nanoparticles","volume":"4","author":"Wong","year":"2009","journal-title":"ChemMedChem"},{"key":"10.1016\/j.msec.2018.05.020_bb0105","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1007\/s11051-014-2605-x","article-title":"An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles","volume":"16","author":"Kaler","year":"2014","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0110","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1080\/21691401.2017.1324461","article-title":"Anti-pseudomonal and anti-endotoxic effects of surfactin-stabilized biogenic silver nanocubes ameliorated wound repair in streptozotocin-induced diabetic mice","volume":"46","author":"Krishnan","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"10.1016\/j.msec.2018.05.020_bb0115","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1021\/mp900056g","article-title":"Silver nanoparticles in therapeutics: development of an antimicrobial gel formulation for topical use","volume":"6","author":"Jain","year":"2009","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.msec.2018.05.020_bb0120","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/cmdc.200600171","article-title":"Topical delivery of silver nanoparticles promotes wound healing","volume":"2","author":"Tian","year":"2007","journal-title":"ChemMedChem"},{"key":"10.1016\/j.msec.2018.05.020_bb0125","doi-asserted-by":"crossref","first-page":"25798","DOI":"10.1021\/acsami.6b09267","article-title":"Functional silver nanoparticle as a benign antimicrobial agent that eradicates antibiotic-resistant bacteria and promotes wound healing","volume":"8","author":"Dai","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.msec.2018.05.020_bb0130","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00403-010-1066-z","article-title":"A multi-component herbal preparation (PADMA 28) improves structure\/function of corticosteroid-treated skin, leading to improved wound healing of subsequently induced abrasion wounds in rats","volume":"302","author":"Aslam","year":"2010","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.msec.2018.05.020_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073992","article-title":"Delayed wound repair in sepsis is associated with reduced local pro-inflammatory cytokine expression","volume":"8","author":"Sommer","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.msec.2018.05.020_bb0140","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1046\/j.1524-475X.2002.10308.x","article-title":"Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing","volume":"10","author":"Wright","year":"2002","journal-title":"Wound Repair Regen."}],"container-title":["Materials Science and Engineering: C"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493118311524?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493118311524?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T12:25:46Z","timestamp":1760531146000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0928493118311524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":28,"alternative-id":["S0928493118311524"],"URL":"https:\/\/doi.org\/10.1016\/j.msec.2018.05.020","relation":{},"ISSN":["0928-4931"],"issn-type":[{"value":"0928-4931","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of biogenic silver nanocubes on matrix metalloproteinases 2 and 9 expressions in hyperglycemic skin injury and its impact in early wound healing in streptozotocin-induced diabetic mice","name":"articletitle","label":"Article Title"},{"value":"Materials Science and Engineering: C","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msec.2018.05.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}