{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:08:24Z","timestamp":1773918504424,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Science and Engineering: C"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.msec.2019.01.045","type":"journal-article","created":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T01:19:52Z","timestamp":1547515192000},"page":"861-873","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Intraperitoneal transplantation of bioengineered humanized liver grafts supports failing liver in acute condition"],"prefix":"10.1016","volume":"98","author":[{"given":"Sandeep Kumar","family":"Vishwakarma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avinash","family":"Bardia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandrakala","family":"Lakkireddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagarapu","family":"Raju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Ameer Basha","family":"Paspala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Aejaz","family":"Habeeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleem Ahmed","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.msec.2019.01.045_bb0005","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1056\/NEJMra1208937","article-title":"Acute Liver Failure","volume":"369","author":"Bernal","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.msec.2019.01.045_bb0010","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1002\/lt.21931","article-title":"Long-term outcomes of emergency liver transplantation for acute liver failure","volume":"15","author":"Chan","year":"2009","journal-title":"Liver Transpl."},{"key":"10.1016\/j.msec.2019.01.045_bb0015","first-page":"37","article-title":"Liver transplantation for drug-induced acute liver failure","volume":"21","author":"Biolato","year":"2017","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.msec.2019.01.045_bb0020","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.3748\/wjg.v22.i4.1523","article-title":"Liver transplantation in acute liver failure: a challenging scenario","volume":"22","author":"Mendizabal","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.msec.2019.01.045_bb0025","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/00007890-199410270-00016","article-title":"Human fetal hepatocyte transplantation in patients with fulminant hepatic failure","volume":"58","author":"Habibullah","year":"1994","journal-title":"Transplantation"},{"key":"10.1016\/j.msec.2019.01.045_bb0030","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/00007890-199702270-00014","article-title":"Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure","volume":"63","author":"Storm","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.msec.2019.01.045_bb0035","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S1527-6465(00)80030-1","article-title":"Hepatocyte transplantation in acute liver failure","volume":"6","author":"Bilir","year":"2000","journal-title":"Liver Transpl."},{"key":"10.1016\/j.msec.2019.01.045_bb0040","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.jhep.2004.04.009","article-title":"Hepatocyte transplantation","volume":"40","author":"Fox","year":"2004","journal-title":"J. Hepatol."},{"key":"10.1016\/j.msec.2019.01.045_bb0045","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.1016\/j.transproceed.2005.06.027","article-title":"Human hepatocyte transplantation for acute liver failure: state of the art and analysis of cell sources","volume":"37","author":"Baccarani","year":"2005","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.msec.2019.01.045_bb0050","first-page":"309","article-title":"Integration of technologies for hepatic tissue engineering","volume":"103","author":"Nahmias","year":"2007","journal-title":"Adv. Biochem. Eng. Biotechnol."},{"key":"10.1016\/j.msec.2019.01.045_bb0055","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1089\/tea.2007.0143","article-title":"Three-dimensional primary hepatocyte culture in synthetic self-assembling peptide hydrogel","volume":"14","author":"Wang","year":"2008","journal-title":"Tiss. Eng. Part A"},{"key":"10.1016\/j.msec.2019.01.045_bb0060","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/nbt1361","article-title":"Microscale culture of human liver cells for drug development","volume":"26","author":"Khetani","year":"2008","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.msec.2019.01.045_bb0065","doi-asserted-by":"crossref","first-page":"11842","DOI":"10.1073\/pnas.1101791108","article-title":"Humanized mice with ectopic artificial liver tissues","volume":"108","author":"Alice","year":"2011","journal-title":"PNAS"},{"key":"10.1016\/j.msec.2019.01.045_bb0070","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.mattod.2016.12.005","article-title":"Tissue engineering by decellularization and 3D bioprinting","volume":"20","author":"Garreta","year":"2017","journal-title":"Mater. Today"},{"key":"10.1016\/j.msec.2019.01.045_bb0075","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/MCC.0b013e3282f70057","article-title":"Liver support devices","volume":"14","author":"Phua","year":"2008","journal-title":"Curr. Opin. Crit. Care"},{"key":"10.1016\/j.msec.2019.01.045_bb0080","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1136\/gut.2008.175380","article-title":"Artificial and bioartificial liver devices: present and future","volume":"58","author":"Carpentier","year":"2009","journal-title":"Gut"},{"key":"10.1016\/j.msec.2019.01.045_bb0085","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1263\/jbb.99.311","article-title":"Bioartificial liver systems: current status and future perspective","volume":"99","author":"Park","year":"2005","journal-title":"J. Biosci. Bioeng."},{"key":"10.1016\/j.msec.2019.01.045_bb0090","first-page":"20","article-title":"Artificial and bioartificial liver support","volume":"3","author":"Pless","year":"2007","journal-title":"Organ"},{"key":"10.1016\/j.msec.2019.01.045_bb0095","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1177\/096368979400300403","article-title":"The mesentery as a laminated vascular bed for hepatocyte transplantation","volume":"3","author":"Johnson","year":"1994","journal-title":"Cell Transplant."},{"key":"10.1016\/j.msec.2019.01.045_bb0100","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/S0041-1345(99)00208-0","article-title":"Long-term hepatocyte transplantation using three-dimensional matrices","volume":"31","author":"Kaufmann","year":"1999","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.msec.2019.01.045_bb0105","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/nm.2193","article-title":"Regeneration and orthotopic transplantation of a bioartificial lung","volume":"16","author":"Ott","year":"2010","journal-title":"Nat. Med."},{"key":"10.1016\/j.msec.2019.01.045_bb0110","first-page":"26","article-title":"Whole organ decellularization: a tool for bioscaffold fabrication and organ bioengineering","volume":"65","author":"Baptista","year":"2010","journal-title":"Conf. Proc. IEEE Eng. Med. Biol. Soc."},{"key":"10.1016\/j.msec.2019.01.045_bb0115","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/hep.24067","article-title":"The use of whole organ decellularization for the generation of a vascularised liver organoid","volume":"53","author":"Baptista","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.msec.2019.01.045_bb0120","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/978-1-62703-363-3_24","article-title":"Human liver bioengineering using a whole liver decellularized bioscaffold","volume":"1001","author":"Baptista","year":"2013","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.msec.2019.01.045_bb0125","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.jss.2011.09.033","article-title":"Use of decellularized porcine liver for engineering humanized liver organ","volume":"173","author":"Barakat","year":"2012","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.msec.2019.01.045_bb0130","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1016\/j.jcyt.2014.01.330","article-title":"Decellularized liver scaffold as a potential resource for the development of functional humanized liver","volume":"16","author":"Khan","year":"2014","journal-title":"Cytotherapy"},{"key":"10.1016\/j.msec.2019.01.045_bb0135","doi-asserted-by":"crossref","first-page":"372","DOI":"10.4103\/0971-4065.133008","article-title":"Preparation of natural three-dimensional goat kidney scaffold for the development of bioartificial organ","volume":"24","author":"Vishwakarma","year":"2014","journal-title":"Ind. J. Nephrol."},{"key":"10.1016\/j.msec.2019.01.045_bb0140","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/nm.2170","article-title":"Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix","volume":"16","author":"Uygun","year":"2010","journal-title":"Nat. Med."},{"key":"10.1016\/j.msec.2019.01.045_bb0145","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.transproceed.2011.05.014","article-title":"Bioengineering in organ transplantation: targeting the liver","volume":"43","author":"Fukumitsu","year":"2011","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.msec.2019.01.045_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-05134-1","article-title":"Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization","volume":"7","author":"Mazza","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.msec.2019.01.045_bb0155","article-title":"Decellularized heart: a step towards creating personalized bioengineered organ","volume":"1","author":"Rout","year":"2014","journal-title":"Curr. Sci."},{"key":"10.1016\/j.msec.2019.01.045_bb0160","doi-asserted-by":"crossref","first-page":"S207","DOI":"10.1016\/S0168-8278(14)60580-8","article-title":"Development of extra-corporeal bioartificial liver by repopulating the decellularized goat liver scaffold using human hepatic progenitors","volume":"60","author":"Habeeb","year":"2014","journal-title":"J. Hepatol."},{"key":"10.1016\/j.msec.2019.01.045_bb0165","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/jdi.12193","article-title":"In vitro quantitative and relative gene expression analysis of pancreatic transcription factors Pdx-1, Ngn-3, Isl-1, Pax-4, Pax-6 and Nkx-6.1 in trans-differentiated human hepatic progenitors","volume":"5","author":"Vishwakarma","year":"2014","journal-title":"J. Diab. Invest."},{"key":"10.1016\/j.msec.2019.01.045_bb0170","first-page":"006","article-title":"Isolation and characterization of stem cells sub population within the human fetal liver","volume":"S1","author":"Vali","year":"2014","journal-title":"Cell Biol. Res. Ther."},{"key":"10.1016\/j.msec.2019.01.045_bb0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep35887","article-title":"Efficient recellularisation of decellularised whole-liver grafts using biliary tree and foetal hepatocytes","volume":"6","author":"Ogiso","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.msec.2019.01.045_bb0180","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s40824-016-0074-2","article-title":"Solid organ fabrication: comparison of decellularization to 3D bioprinting","volume":"20","author":"Jung","year":"2016","journal-title":"Biomat. Res."},{"key":"10.1016\/j.msec.2019.01.045_bb0185","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1089\/ten.tea.2015.0313","article-title":"Decellularized liver extracellular matrix as promising tools for transplantable bioengineered liver promotes hepatic lineage commitments of induced pluripotent stem cells","volume":"22","author":"Park","year":"2016","journal-title":"Tiss. Eng. Part A"},{"key":"10.1016\/j.msec.2019.01.045_bb0190","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/jbm.b.33384","article-title":"Three dimensional culture of HepG2 liver cells on a rat decellularized liver matrix for pharmacological studies","volume":"104","author":"Hussein","year":"2016","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.msec.2019.01.045_bb0195","series-title":"Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization","author":"Fraise","year":"2004"},{"key":"10.1016\/j.msec.2019.01.045_bb0200","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1530\/rep.0.1230217","article-title":"Peritoneal environment, cytokines and angiogenesis in the pathophysiology of endometriosis","volume":"123","author":"Gazvani","year":"2002","journal-title":"Reproduction"},{"key":"10.1016\/j.msec.2019.01.045_bb0205","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1001\/archinte.1979.03630430056018","article-title":"Trace element composition of ascetic fluid","volume":"139","author":"Burch","year":"1979","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.msec.2019.01.045_bb0210","article-title":"Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure","volume":"9","author":"Jitaruch","year":"2014","journal-title":"PLoS One"}],"container-title":["Materials Science and Engineering: C"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493117344946?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493117344946?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T16:33:17Z","timestamp":1550939597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0928493117344946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":42,"alternative-id":["S0928493117344946"],"URL":"https:\/\/doi.org\/10.1016\/j.msec.2019.01.045","relation":{},"ISSN":["0928-4931"],"issn-type":[{"value":"0928-4931","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intraperitoneal transplantation of bioengineered humanized liver grafts supports failing liver in acute condition","name":"articletitle","label":"Article Title"},{"value":"Materials Science and Engineering: C","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msec.2019.01.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}