{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T05:37:19Z","timestamp":1782797839643,"version":"3.54.5"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences and Health Services","doi-asserted-by":"publisher","award":["95-04-38-33568"],"award-info":[{"award-number":["95-04-38-33568"]}],"id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials Advances"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.msec.2021.112634","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T01:39:56Z","timestamp":1640828396000},"page":"112634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Influence of reducing agents on in situ synthesis of gold nanoparticles and scaffold conductivity with emphasis on neural differentiation"],"prefix":"10.1016","volume":"134","author":[{"given":"Milad","family":"Rahimzadegan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qazal","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Shafieian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omid","family":"Sabzevari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Hassannejad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.msec.2021.112634_bb0005","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/jbm.a.37023","article-title":"Fabrication and in vitro evaluation of 3D composite scaffold based on collagen\/hyaluronic acid sponge and electrospun polycaprolactone nanofibers for peripheral nerve regeneration","volume":"109","author":"Entekhabi","year":"2021","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"11","key":"10.1016\/j.msec.2021.112634_bb0010","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.biomaterials.2004.04.040","article-title":"Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole","volume":"26","author":"Verreck","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.msec.2021.112634_bb0015","first-page":"405","article-title":"Peripheral nerve conduits: technology update","volume":"7","author":"Arslantunali","year":"2014","journal-title":"Med. Devices (Auckland, NZ)"},{"key":"10.1016\/j.msec.2021.112634_bb0020","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0074-7742(09)87009-8","article-title":"Artificial scaffolds for peripheral nerve reconstruction","volume":"87","author":"Chiono","year":"2009","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.msec.2021.112634_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120164","article-title":"Application of conductive PPy\/SF composite scaffold and electrical stimulation for neural tissue engineering","volume":"255","author":"Zhao","year":"2020","journal-title":"Biomaterials"},{"issue":"28","key":"10.1016\/j.msec.2021.112634_bb0030","doi-asserted-by":"crossref","first-page":"6591","DOI":"10.1039\/D0SM00593B","article-title":"Electrospun cellulose-based conductive polymer nanofibrous mats: composite scaffolds and their influence on cell behavior with electrical stimulation for nerve tissue engineering","volume":"16","author":"Zha","year":"2020","journal-title":"Soft Matter"},{"issue":"4","key":"10.1016\/j.msec.2021.112634_bb0035","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1123\/mcj.13.4.412","article-title":"Brief electrical stimulation accelerates axon regeneration in the peripheral nervous system and promotes sensory axon regeneration in the central nervous system","volume":"13","author":"Gordon","year":"2009","journal-title":"Mot. Control."},{"issue":"2","key":"10.1016\/j.msec.2021.112634_bb0040","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0896-6273(01)00217-3","article-title":"Electrical activity modulates growth cone guidance by diffusible factors","volume":"29","author":"Ming","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.msec.2021.112634_bb0045","series-title":"Fabrication and Characterization of Conductive Chitosan\/gelatin-based Scaffolds for Nerve Tissue Engineering","first-page":"360","volume":"74","author":"Baniasadi","year":"2015"},{"issue":"6","key":"10.1016\/j.msec.2021.112634_bb0050","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1021\/nl050637m","article-title":"Carbon nanotube substrates boost neuronal electrical signaling","volume":"5","author":"Lovat","year":"2005","journal-title":"Nano Lett."},{"issue":"2","key":"10.1016\/j.msec.2021.112634_bb0055","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.biomaterials.2013.10.011","article-title":"Cancer stem cell therapy using doxorubicin conjugated to gold nanoparticles via hydrazone bonds","volume":"35","author":"Sun","year":"2014","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.msec.2021.112634_bb0060","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.nano.2011.10.012","article-title":"Photothermal release of small molecules from gold nanoparticles in live cells","volume":"8","author":"Zandberg","year":"2012","journal-title":"Nanomedicine"},{"issue":"48","key":"10.1016\/j.msec.2021.112634_bb0065","doi-asserted-by":"crossref","first-page":"17104","DOI":"10.1073\/pnas.1418637111","article-title":"NanoFlares for the detection, isolation, and culture of live tumor cells from human blood","volume":"111","author":"Halo","year":"2014","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.msec.2021.112634_bb0070","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1002\/adhm.201200238","article-title":"Near-infrared fluorescent silica-coated gold nanoparticle clusters for X-ray computed Tomography\/Optical dual modal imaging of the lymphatic system","volume":"2","author":"Hayashi","year":"2013","journal-title":"Adv. Healthc. Mater."},{"issue":"2","key":"10.1016\/j.msec.2021.112634_bb0075","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cossms.2016.03.006","article-title":"Recent advances using gold nanoparticles as a promising multimodal tool for tissue engineering and regenerative medicine","volume":"21","author":"Vial","year":"2017","journal-title":"Curr. Opinion Solid State Mater. Sci."},{"issue":"3","key":"10.1016\/j.msec.2021.112634_bb0080","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.biotechadv.2010.01.004","article-title":"Electrospinning: a fascinating fiber fabrication technique","volume":"28","author":"Bhardwaj","year":"2010","journal-title":"Biotechnol. Adv."},{"issue":"12","key":"10.1016\/j.msec.2021.112634_bb0085","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1016\/S0142-9612(02)00635-X","article-title":"A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering","volume":"24","author":"Yoshimoto","year":"2003","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.msec.2021.112634_bb0090","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cytogfr.2005.05.001","article-title":"Delivery of bone morphogenetic proteins for orthopedic tissue regeneration","volume":"16","author":"Seeherman","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"issue":"2","key":"10.1016\/j.msec.2021.112634_bb0095","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1080\/09205063.2015.1111717","article-title":"DBD atmospheric plasma-modified, electrospun, layer-by-layer polymeric scaffolds for L929 fibroblast cell cultivation","volume":"27","author":"Surucu","year":"2016","journal-title":"J. Biomater. Sci. Polym. Ed."},{"issue":"9","key":"10.1016\/j.msec.2021.112634_bb0100","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1007\/s10856-018-6144-3","article-title":"Fabrication and characterization of gold nanoparticle-doped electrospun PCL\/chitosan nanofibrous scaffolds for nerve tissue engineering","volume":"29","author":"Saderi","year":"2018","journal-title":"J. Mater. Sci. Mater. Med."},{"issue":"1\u20132","key":"10.1016\/j.msec.2021.112634_bb0105","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jhazmat.2006.11.049","article-title":"Adsorption of platinum (IV), palladium (II) and gold (III) from aqueous solutions onto l-lysine modified crosslinked chitosan resin","volume":"146","author":"Fujiwara","year":"2007","journal-title":"J. Hazard. Mater."},{"issue":"4","key":"10.1016\/j.msec.2021.112634_bb0110","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1021\/bm060030f","article-title":"Chitosan-mediated synthesis of gold nanoparticles on patterned poly (dimethylsiloxane) surfaces","volume":"7","author":"Wang","year":"2006","journal-title":"Biomacromolecules"},{"issue":"3","key":"10.1016\/j.msec.2021.112634_bb0115","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.optmat.2012.10.019","article-title":"Synthesis and evaluation of time dependent optical properties of plasmonic\u2013magnetic nanoparticles","volume":"35","author":"Hassannejad","year":"2013","journal-title":"Opt. Mater."},{"issue":"4","key":"10.1016\/j.msec.2021.112634_bb0120","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.carbpol.2012.01.085","article-title":"Polycaprolactone\/chitosan blend nanofibres electrospun from an acetic acid\/formic acid solvent system","volume":"88","author":"Van der Schueren","year":"2012","journal-title":"Carbohydr. Polym."},{"issue":"26","key":"10.1016\/j.msec.2021.112634_bb0125","doi-asserted-by":"crossref","first-page":"10427","DOI":"10.1039\/c3ra40774h","article-title":"Beyond gold: rediscovering tetrakis-(hydroxymethyl)-phosphonium chloride (THPC) as an effective agent for the synthesis of ultra-small noble metal nanoparticles and Pt-containing nanoalloys","volume":"3","author":"Hueso","year":"2013","journal-title":"RSC Adv."},{"issue":"4","key":"10.1016\/j.msec.2021.112634_bb0130","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1002\/jbm.b.33968","article-title":"Fabrication and characterization of electrospun laminin-functionalized silk fibroin\/poly (ethylene oxide) nanofibrous scaffolds for peripheral nerve regeneration","volume":"106","author":"Rajabi","year":"2018","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"5","key":"10.1016\/j.msec.2021.112634_bb0135","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1002\/cbin.11315","article-title":"Microtubule stabilizer epothilone B as a motor neuron differentiation agent for human endometrial stem cells","volume":"44","author":"Mahmoodi","year":"2020","journal-title":"Cell Biol. Int."},{"issue":"2","key":"10.1016\/j.msec.2021.112634_bb0140","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.carres.2003.10.024","article-title":"Synthesis and antimicrobial activity of a water-soluble chitosan derivative with a fiber-reactive group","volume":"339","author":"Lim","year":"2004","journal-title":"Carbohydr. Res."},{"issue":"1","key":"10.1016\/j.msec.2021.112634_bb0145","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3390\/md13010141","article-title":"Does the use of chitosan contribute to oxalate kidney stone formation?","volume":"13","author":"Fernandes Queiroz","year":"2014","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.msec.2021.112634_bb0150","series-title":"Preparation and Physicochemical Characterization of Biodegradable Nerve Guides Containing the Nerve Growth Agent Sabeluzole","first-page":"1307","volume":"26(11)","author":"Verreck","year":"2005"},{"issue":"7","key":"10.1016\/j.msec.2021.112634_bb0155","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1002\/term.348","article-title":"Characterization of electrospun poly (L-lactide) and gold nanoparticle composite scaffolds for skeletal muscle tissue engineering","volume":"5","author":"McKeon-Fischer","year":"2011","journal-title":"J. Tissue Regen. Med"},{"key":"10.1016\/j.msec.2021.112634_bb0160","series-title":"Gold Nanorod-embedded Electrospun Fibrous Membrane as a Photothermal Therapy Platform","first-page":"1569","volume":"6(3)","author":"Cheng","year":"2014"},{"key":"10.1016\/j.msec.2021.112634_bb0165","series-title":"Spontaneous Formation of Gold Nanoparticles in Aqueous Solution of Sugar-persubstituted Poly (amidoamine) Dendrimers","first-page":"2978","volume":"16(6)","author":"Esumi","year":"2000"},{"key":"10.1016\/j.msec.2021.112634_bb0170","series-title":"Adsorption of Platinum (IV), Palladium (II) and Gold (III) From Aqueous Solutions Onto l-Lysine Modified Crosslinked Chitosan resin","first-page":"39","volume":"146(1-2)","author":"Fujiwara","year":"2007"},{"key":"10.1016\/j.msec.2021.112634_bb0175","series-title":"Chitosan-mediated Synthesis of Gold Nanoparticles on Patterned Poly (dimethylsiloxane) Surfaces","first-page":"1203","volume":"7(4)","author":"Wang","year":"2006"},{"key":"10.1016\/j.msec.2021.112634_bb0180","series-title":"Fabrication and Characterization of Gold Nanoparticle-doped Electrospun PCL\/chitosan Nanofibrous Scaffolds for Nerve Tissue Engineering","first-page":"1","volume":"29(9)","author":"Saderi","year":"2018"},{"issue":"4","key":"10.1016\/j.msec.2021.112634_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10856-021-06519-5","article-title":"Fabrication and evaluation of porous and conductive nanofibrous scaffolds for nerve tissue engineering","volume":"32","author":"Pooshidani","year":"2021","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"10.1016\/j.msec.2021.112634_bb0190","series-title":"A New Hydrosol of Gold Clusters. 1. Formation and Particle Size Variation","first-page":"2301","volume":"9(9)","author":"Duff","year":"1993"},{"key":"10.1016\/j.msec.2021.112634_bb0195","first-page":"10427","article-title":"Beyond gold: rediscovering tetrakis-(hydroxymethyl)-phosphonium chloride (THPC) as an effective agent for the synthesis of ultra-small noble metal nanoparticles and Pt-containing nanoalloys","volume":"3(26)","author":"Hueso","year":"2013"},{"issue":"9","key":"10.1016\/j.msec.2021.112634_bb0200","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1021\/la00033a010","article-title":"A new hydrosol of gold clusters. 1. Formation and particle size variation","volume":"9","author":"Duff","year":"1993","journal-title":"Langmuir"},{"issue":"89","key":"10.1016\/j.msec.2021.112634_bb0205","doi-asserted-by":"crossref","first-page":"56732","DOI":"10.1039\/C7RA12062A","article-title":"Improving osteogenesis of PLGA\/HA porous scaffolds based on dual delivery of BMP-2 and IGF-1 via a polydopamine coating","volume":"7","author":"Zhang","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.msec.2021.112634_bb0210","series-title":"Fabrication and Characterization of Hydrophilic Poly (\u03b5-caprolactone)\/pluronic P123 Electrospun Fibers","volume":"133(17)","author":"Mirhosseini","year":"2016"},{"key":"10.1016\/j.msec.2021.112634_bb0215","series-title":"Systematic Characterization of 3D-printed PCL\/\u03b2-TCP Scaffolds for Biomedical Devices and Bone Tissue Engineering: Influence of Composition and Porosity","first-page":"1948","volume":"33(14)","author":"Bruyas","year":"2018"},{"issue":"3","key":"10.1016\/j.msec.2021.112634_bb0220","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3390\/jfb10030030","article-title":"Strategies to tune electrospun scaffold porosity for effective cell response in tissue engineering","volume":"10","author":"Ameer","year":"2019","journal-title":"J. Funct. Biomater."},{"key":"10.1016\/j.msec.2021.112634_bb0225","series-title":"Large Three-dimensional Poly (glycerol sebacate)-based Scaffolds\u2013A Freeze-drying Preparation Approach","first-page":"6650","volume":"1(48)","author":"Frydrych","year":"2013"},{"key":"10.1016\/j.msec.2021.112634_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2019.109960","article-title":"Preparation and characterization of PLA\/PCL\/HA composite scaffolds using Indirect 3D printing for bone tissue engineering","volume":"104","author":"Hassanajili","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.msec.2021.112634_bb0235","series-title":"Microfluidic Fabrication of Alendronate-loaded Chitosan Nanoparticles for Enhanced Osteogenic Differentiation of Stem Cells","volume":"254","author":"Moradikhah","year":"2020"},{"key":"10.1016\/j.msec.2021.112634_bb0240","doi-asserted-by":"crossref","unstructured":"S Soheili E Mandegar F Moradikhah M Doosti-Telgerd HA Javar JJoDDS, Technology. Experimental and numerical studies on microfluidic preparation and engineering of chitosan nanoparticles.61:102268.","DOI":"10.1016\/j.jddst.2020.102268"},{"key":"10.1016\/j.msec.2021.112634_bb0245","series-title":"Fabrication and Characterization of PCL\/gelatin\/chitosan Ternary Nanofibrous Composite Scaffold for Tissue Engineering Applications","first-page":"1076","volume":"49(3)","author":"Gautam","year":"2014"},{"key":"10.1016\/j.msec.2021.112634_bb0250","series-title":"Mechanical Properties of Acellular Peripheral Nerve","first-page":"133","volume":"114(2)","author":"Borschel","year":"2003"}],"container-title":["Biomaterials Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493121007748?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928493121007748?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T21:12:06Z","timestamp":1760649126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0928493121007748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":50,"alternative-id":["S0928493121007748"],"URL":"https:\/\/doi.org\/10.1016\/j.msec.2021.112634","relation":{},"ISSN":["2772-9508"],"issn-type":[{"value":"2772-9508","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of reducing agents on in situ synthesis of gold nanoparticles and scaffold conductivity with emphasis on neural differentiation","name":"articletitle","label":"Article Title"},{"value":"Biomaterials Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.msec.2021.112634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112634"}}