{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:47:59Z","timestamp":1792097279009,"version":"4.4.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/P001114\/1"],"award-info":[{"award-number":["EP\/P001114\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201908060063"],"award-info":[{"award-number":["201908060063"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.mtbio.2022.100367","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T22:46:49Z","timestamp":1658184409000},"page":"100367","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis"],"prefix":"10.1016","volume":"16","author":[{"given":"Yinbo","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Sprott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineetha","family":"Jayawarna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro","family":"Lemgruber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Monica","family":"Tsimbouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.M. Dominic","family":"Meek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Salmeron-Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Dalby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mtbio.2022.100367_bib1","article-title":"An engineered biomimetic peptide regulates cell behavior by synergistic integrin and growth factor signaling","volume":"10","author":"Oliver-Cervell\u00f3","year":"2021","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.mtbio.2022.100367_bib2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/s41578-018-0023-x","article-title":"Extracellular matrix-based materials for regenerative medicine","volume":"3","author":"Hussey","year":"2018","journal-title":"Nat. Rev. Mater."},{"issue":"2014","key":"10.1016\/j.mtbio.2022.100367_bib3","first-page":"885","article-title":"Matrix enhance tissue healing","volume":"343","author":"Martino","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2022.100367_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201700052","article-title":"Mechanotransduction and growth factor signalling to engineer cellular microenvironments","volume":"6","author":"Cipitria","year":"2017","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.mtbio.2022.100367_bib5","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41580-019-0134-2","article-title":"Integrins as biomechanical sensors of the microenvironment","volume":"20","author":"Kechagia","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib6","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1126\/science.1176009","article-title":"The extracellular matrix: not just pretty fibrils","volume":"326","author":"Hynes","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2022.100367_bib7","doi-asserted-by":"crossref","DOI":"10.1038\/natrevmats.2017.91","article-title":"Receptor control in mesenchymal stem cell engineering","volume":"3","author":"Dalby","year":"2018","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.mtbio.2022.100367_bib8","series-title":"Cell Biology of Extracellular Matrix","author":"Mecham","year":"2011"},{"key":"10.1016\/j.mtbio.2022.100367_bib9","doi-asserted-by":"crossref","first-page":"20180318","DOI":"10.1098\/rsif.2018.0388","article-title":"Designing stem cell niches for differentiation and self-renewal","volume":"15","author":"Donnelly","year":"2018","journal-title":"J.\u00a0R. Soc. Interface"},{"key":"10.1016\/j.mtbio.2022.100367_bib10","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/jbm.a.32374","article-title":"Fibronectin activity on substrates with controlled - OH density","volume":"92","author":"Gugutkov","year":"2010","journal-title":"J.\u00a0Biomed. Mater. Res. - Part A"},{"key":"10.1016\/j.mtbio.2022.100367_bib11","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/j.biomaterials.2010.11.057","article-title":"Role of material-driven fibronectin fibrillogenesis in cell differentiation","volume":"32","author":"Salmer\u00f3n-S\u00e1nchez","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2022.100367_bib12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.biomaterials.2017.02.024","article-title":"Engineered microenvironments for synergistic VEGF \u2013 integrin signalling during vascularization","volume":"126","author":"Moulisov\u00e1","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2022.100367_bib13","article-title":"Nanoscale coatings for ultralow dose BMP-2-driven regeneration of critical-sized bone defects","volume":"6","author":"Cheng","year":"2019","journal-title":"Adv. Sci."},{"key":"10.1016\/j.mtbio.2022.100367_bib14","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1600188","article-title":"Material-driven fibronectin assembly for high-efficiency presentation of growth factors","volume":"2","author":"Llopis-Hern\u00e1ndez","year":"2016","journal-title":"Sci. Adv."},{"key":"10.1016\/j.mtbio.2022.100367_bib15","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/iub.1203","article-title":"Vitronectin - master controller or micromanager?","volume":"65","author":"Leavesley","year":"2013","journal-title":"IUBMB Life"},{"key":"10.1016\/j.mtbio.2022.100367_bib16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1083\/jcb.130.3.503","article-title":"Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1","volume":"130","author":"Bornstein","year":"1995","journal-title":"JCB (J. Cell Biol.)"},{"key":"10.1016\/j.mtbio.2022.100367_bib17","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1021\/acsbiomaterials.5b00147","article-title":"Dynamic behavior of vitronectin at the cell-material interface","volume":"1","author":"Toromanov","year":"2015","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.mtbio.2022.100367_bib18","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1042\/bj3070867","article-title":"Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells","volume":"307","author":"Moser","year":"1995","journal-title":"Biochem. J."},{"key":"10.1016\/j.mtbio.2022.100367_bib19","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/0955-0674(93)90036-P","article-title":"Vitronectin and its receptors","volume":"5","author":"Felding-Habermann","year":"1993","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib20","series-title":"Vitronectin","author":"Su","year":"2018"},{"key":"10.1016\/j.mtbio.2022.100367_bib21","doi-asserted-by":"crossref","first-page":"16245","DOI":"10.1073\/pnas.0902818106","article-title":"Clustering of \u03b15\u03b21 integrins determines adhesion strength whereas \u03b1v\u03b23 and talin enable mechanotransduction","volume":"106","author":"Roca-Cusachs","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mtbio.2022.100367_bib22","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1083\/jcb.148.5.1075","article-title":"Integrin dynamics and matrix assembly: tensin-dependent translocation of \u03b15\u03b21 integrins promotes early fibronectin fibrillogenesis","volume":"148","author":"Pankov","year":"2000","journal-title":"JCB (J. Cell Biol.)"},{"key":"10.1016\/j.mtbio.2022.100367_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adbi.201700047","article-title":"Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks","volume":"1","author":"Cantini","year":"2017","journal-title":"Adv. Biosyst."},{"key":"10.1016\/j.mtbio.2022.100367_bib24","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.colsurfb.2013.07.016","article-title":"Vitronectin alters fibronectin organization at the cell-material interface","volume":"111","author":"Gonz\u00e1lez-Garc\u00eda","year":"2013","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.mtbio.2022.100367_bib25","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/j.polymer.2010.03.041","article-title":"Vitronectin activity on polymer substrates with controlled -OH density","volume":"51","author":"Toromanov","year":"2010","journal-title":"Polymer"},{"key":"10.1016\/j.mtbio.2022.100367_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.110966","article-title":"Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors","volume":"113","author":"Alba-Perez","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.mtbio.2022.100367_bib27","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1007\/s00264-018-4153-y","article-title":"Bone morphogenetic proteins in fracture repair","volume":"42","author":"Dumic-Cule","year":"2018","journal-title":"Int. Orthop."},{"key":"10.1016\/j.mtbio.2022.100367_bib28","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.cytogfr.2005.02.004","article-title":"Application of bone morphogenetic proteins in spinal fusion","volume":"16","author":"Gupta","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.mtbio.2022.100367_bib29","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.mex.2014.06.004","article-title":"Step-by-step quantitative analysis of focal adhesions","volume":"1","author":"Horzum","year":"2014","journal-title":"MethodsX"},{"key":"10.1016\/j.mtbio.2022.100367_bib30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0368-2048(93)85006-7","article-title":"High resolution XPS of organic polymers: the Scienta ESCA300 database","volume":"62","author":"Pireaux","year":"1993","journal-title":"J.\u00a0Electron. Spectrosc. Relat. Phenom."},{"key":"10.1016\/j.mtbio.2022.100367_bib31","article-title":"Functionalization of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks","volume":"8","author":"Sprott","year":"2019","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.mtbio.2022.100367_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-12-816137-1.00091-X","article-title":"Sterilization and disinfection of biomaterials for medical devices","author":"Harrington","year":"2020","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.mtbio.2022.100367_bib33","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1242\/jcs.00059","article-title":"Fibronectin at a glance","volume":"115","author":"Pankov","year":"2002","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.mtbio.2022.100367_bib34","first-page":"4711","article-title":"The 12th\u201314th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain","volume":"24","author":"Martino","year":"2010","journal-title":"Faseb. J."},{"key":"10.1016\/j.mtbio.2022.100367_bib35","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/nature09621","article-title":"Nanoscale architecture of integrin-based cell adhesions","volume":"468","author":"Kanchanawong","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.mtbio.2022.100367_bib36","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1126\/science.1069040","article-title":"Crystal structure of the extracellular segment of integrin \u03b1V\u03b23 in complex with an Arg-Gly-Asp ligand","volume":"296","author":"Xiong","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2022.100367_bib37","doi-asserted-by":"crossref","first-page":"4607","DOI":"10.1093\/emboj\/cdg445","article-title":"Structure of integrin \u03b15\u03b21 in complex with fibronectin","volume":"22","author":"Takagi","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.mtbio.2022.100367_bib38","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1359\/jbmr.060109","article-title":"BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype","volume":"21","author":"Phimphilai","year":"2006","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.mtbio.2022.100367_bib39","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.mattod.2017.07.002","article-title":"Functional polymer surfaces for controlling cell behaviors","volume":"21","author":"Chen","year":"2018","journal-title":"Mater. Today"},{"key":"10.1016\/j.mtbio.2022.100367_bib40","first-page":"1044","article-title":"Insight into vitronectin structural evolution on material surface chemistries: the mediation for cell adhesion","volume":"5","author":"Li","year":"2020","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.mtbio.2022.100367_bib41","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1021\/bm501873g","article-title":"Adsorption force of fibronectin on various surface chemistries and its vital role in osteoblast adhesion","volume":"16","author":"Lin","year":"2015","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.mtbio.2022.100367_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2008.09.048","article-title":"The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers","volume":"30","author":"Barrias","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2022.100367_bib43","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/jbm.a.10537","article-title":"Surface chemistry modulates fibronectin conformation and directs integrin binding and specificity to control cell adhesion","volume":"66","author":"Keselowsky","year":"2003","journal-title":"J.\u00a0Biomed. Mater. Res. - Part A"},{"key":"10.1016\/j.mtbio.2022.100367_bib44","series-title":"The Extracellular Matrix: an Overview","year":"2011"},{"key":"10.1016\/j.mtbio.2022.100367_bib45","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1083\/jcb.200205014","article-title":"The fibronectin-binding integrins \u03b15\u03b21 and \u03b1v\u03b23 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis","volume":"159","author":"Danen","year":"2002","journal-title":"JCB (J. Cell Biol.)"},{"key":"10.1016\/j.mtbio.2022.100367_bib46","doi-asserted-by":"crossref","DOI":"10.1002\/iub.200","article-title":"Giving off mixed signals - distinct functions of \u03b15\u03b2 1 and \u03b1v\u03b23 integrins in regulating cell behaviour","volume":"61","author":"Morgan","year":"2009","journal-title":"IUBMB Life"},{"key":"10.1016\/j.mtbio.2022.100367_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/S0955-0674(03)00096-6","article-title":"Interactions between growth factor receptors and adhesion molecules: breaking the rules","volume":"15","author":"Comoglio","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120484","article-title":"Surface Co-presentation of BMP-2 and integrin selective ligands at the nanoscale favors \u03b15\u03b21 integrin-mediated adhesion","volume":"267","author":"Posa","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2022.100367_bib49","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1083\/jcb.201508018","article-title":"\u03b23 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner","volume":"212","author":"Fourel","year":"2016","journal-title":"JCB (J. Cell Biol.)"},{"key":"10.1016\/j.mtbio.2022.100367_bib50","doi-asserted-by":"crossref","first-page":"3960","DOI":"10.1242\/jcs.031286","article-title":"BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity","volume":"121","author":"Gamell","year":"2008","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.mtbio.2022.100367_bib51","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3002614","article-title":"Engineering the growth factor microenvironment with fibronectin domains to promote wound and bone tissue healing","volume":"3","author":"Martino","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.mtbio.2022.100367_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2015.04.007","article-title":"Extracellular matrix-inspired growth factor delivery systems for bone regeneration","volume":"94","author":"Martino","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.mtbio.2022.100367_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.actbio.2015.11.007","article-title":"Engineering growth factors for regenerative medicine applications","volume":"30","author":"Mitchell","year":"2016","journal-title":"Acta Biomater."},{"key":"10.1016\/j.mtbio.2022.100367_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/35010517","article-title":"FAK integrates growth-factor and integrin signals to promote cell migration","volume":"2","author":"Sieg","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib55","doi-asserted-by":"crossref","DOI":"10.1038\/35023515","article-title":"Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins","volume":"2","author":"Ivankovic-Dikic","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib56","doi-asserted-by":"crossref","DOI":"10.3310\/hta11300","article-title":"Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review","volume":"11","author":"Garrison","year":"2007","journal-title":"Health Technol. Assess."},{"key":"10.1016\/j.mtbio.2022.100367_bib57","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.joms.2011.09.008","article-title":"Adverse events reported after the use of recombinant human bone morphogenetic protein 2","volume":"70","author":"Woo","year":"2012","journal-title":"J.\u00a0Oral Maxillofac. Surg."},{"key":"10.1016\/j.mtbio.2022.100367_bib58","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1007\/s11999-012-2684-x","article-title":"Adverse events after recombinant human BMP2 in nonspinal orthopaedic procedures general","volume":"471","author":"Woo","year":"2013","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.mtbio.2022.100367_bib59","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.spinee.2012.09.052","article-title":"Recombinant human bone morphogenetic protein-2: adverse events reported to the Manufacturer and User Facility Device Experience database","volume":"12","author":"Woo","year":"2012","journal-title":"Spine J."},{"key":"10.1016\/j.mtbio.2022.100367_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2012.10.015","article-title":"Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment","volume":"34","author":"Kisiel","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2022.100367_bib61","doi-asserted-by":"crossref","DOI":"10.1039\/c1ib00021g","article-title":"Harnessing endogenous growth factor activity modulates stem cell behavior","volume":"3","author":"Hudalla","year":"2011","journal-title":"Integr. Biol."},{"key":"10.1016\/j.mtbio.2022.100367_bib62","first-page":"111","article-title":"Presentation of BMP-2 from a soft biopolymeric film unveils its activity on cell adhesion and migration","volume":"23","author":"Crouzier","year":"2011","journal-title":"Adv. Mater."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642200165X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642200165X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:34:16Z","timestamp":1762907656000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S259000642200165X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":62,"alternative-id":["S259000642200165X"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2022.100367","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2022.100367","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100367"}}