{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:27:17Z","timestamp":1782775637041,"version":"3.54.5"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T00:00:00Z","timestamp":1666051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902234"],"award-info":[{"award-number":["81902234"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81972088"],"award-info":[{"award-number":["81972088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072469"],"award-info":[{"award-number":["82072469"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072471"],"award-info":[{"award-number":["82072471"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272531"],"award-info":[{"award-number":["82272531"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["19440741300"],"award-info":[{"award-number":["19440741300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic Research Leader","doi-asserted-by":"publisher","award":["21XD1404800"],"award-info":[{"award-number":["21XD1404800"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014137","name":"Shanghai Shenkang Hospital Development Center","doi-asserted-by":"publisher","award":["SHDC2020CR6018"],"award-info":[{"award-number":["SHDC2020CR6018"]}],"id":[{"id":"10.13039\/501100014137","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.mtbio.2022.100469","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T22:52:22Z","timestamp":1667083942000},"page":"100469","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Continuous release of mefloquine featured in electrospun fiber membranes alleviates epidural fibrosis and aids in sensory neurological function after lumbar laminectomy"],"prefix":"10.1016","volume":"17","author":[{"given":"Zhihao","family":"Yue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genjiang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fazhi","family":"Zang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinglei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huajiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.mtbio.2022.100469_bib1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.5435\/00124635-200609000-00003","article-title":"Failed back surgery syndrome: diagnostic evaluation","volume":"14","author":"Guyer","year":"2006","journal-title":"J.\u00a0Am. Acad. Orthop. Surg."},{"key":"10.1016\/j.mtbio.2022.100469_bib2","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3389\/fphar.2018.00402","article-title":"Rapamycin protects against peritendinous fibrosis through activation of autophagy","volume":"9","author":"Zheng","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.mtbio.2022.100469_bib3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2147\/JIR.S254879","article-title":"MicroRNA-21-3p engineered umbilical cord stem cell-derived exosomes inhibit tendon adhesion","volume":"13","author":"Yao","year":"2020","journal-title":"J.\u00a0Inflamm. Res."},{"issue":"6","key":"10.1016\/j.mtbio.2022.100469_bib4","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.surneu.2007.07.071","article-title":"A\u00a0comparison of the local effectiveness of mitomycin C, aprotinin, and Adcon-L in experimental peridural fibrosis","volume":"70","author":"Kurt","year":"2008","journal-title":"Surg. Neurol."},{"issue":"219","key":"10.1016\/j.mtbio.2022.100469_bib5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/00003086-198706000-00017","article-title":"Computed tomography scanning after chymopapain injection for herniated nucleus pulposus. A prospective study","author":"Boumphrey","year":"1987","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.mtbio.2022.100469_bib6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/00007632-199502001-00007","article-title":"No relationship between epidural fibrosis and sciatica in the lumbar postdiscectomy syndrome","volume":"20","author":"Annertz","year":"1995","journal-title":"Spine"},{"key":"10.1016\/j.mtbio.2022.100469_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.774316","article-title":"The preventive effect of decorin on epidural fibrosis and epidural adhesions after laminectomy","volume":"12","author":"Ding","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"5","key":"10.1016\/j.mtbio.2022.100469_bib8","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.spinee.2010.02.025","article-title":"Failed back syndrome and epidural fibrosis","volume":"10","author":"Rabb","year":"2010","journal-title":"Spine J."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1213\/ANE.0000000000000042","article-title":"Epidural lysis of adhesions for failed back surgery and spinal stenosis: factors associated with treatment outcome","volume":"118","author":"Hsu","year":"2014","journal-title":"Anesth. Analg."},{"issue":"6","key":"10.1016\/j.mtbio.2022.100469_bib10","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1053\/j.sempedsurg.2014.06.004","article-title":"The biology of adhesion formation in the peritoneal cavity","volume":"23","author":"Braun","year":"2014","journal-title":"Semin. Pediatr. Surg."},{"issue":"6342","key":"10.1016\/j.mtbio.2022.100469_bib11","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1126\/science.aam7928","article-title":"Inflammation and metabolism in tissue repair and regeneration","volume":"356","author":"Eming","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2022.100469_bib12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.matbio.2017.11.010","article-title":"Inflammation and fibrosis","volume":"68\u201369","author":"Mack","year":"2018","journal-title":"Matrix Biol."},{"issue":"2","key":"10.1016\/j.mtbio.2022.100469_bib13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4103\/ijabmr.IJABMR_349_17","article-title":"Prospective randomized comparative study to evaluate epidural fibrosis and surgical outcome in patients undergoing lumbar laminectomy with epidural autologous free fat graft or gelfoam: a preliminary study","volume":"8","author":"Sobti","year":"2018","journal-title":"Int. J. Appl. Basic Med. Res."},{"issue":"3\u20134","key":"10.1016\/j.mtbio.2022.100469_bib14","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1089\/ten.tea.2012.0208","article-title":"Prevention of peritendinous adhesions with electrospun ibuprofen-loaded poly(L-lactic acid)-polyethylene glycol fibrous membranes","volume":"19","author":"Liu","year":"2013","journal-title":"Tissue Eng."},{"key":"10.1016\/j.mtbio.2022.100469_bib15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.22203\/eCM.v034a19","article-title":"In situ forming oxidised hyaluronic acid\/adipic acid dihydrazide hydrogel for prevention of epidural fibrosis after laminectomy","volume":"34","author":"Hu","year":"2017","journal-title":"Eur. Cell. Mater."},{"issue":"8","key":"10.1016\/j.mtbio.2022.100469_bib16","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1039\/C6BM00958A","article-title":"Macrophage infiltration of electrospun polyester fibers","volume":"5","author":"Liu","year":"2017","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.mtbio.2022.100469_bib17","first-page":"51","article-title":"Biomaterials for adhesion in orthopedic applications: a review","volume":"1","author":"Zaokari","year":"2020","journal-title":"Eng. Regener."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000406","article-title":"A\u00a0research agenda to underpin malaria eradication","volume":"8","author":"Alonso","year":"2011","journal-title":"PLoS Med."},{"issue":"5\u20136","key":"10.1016\/j.mtbio.2022.100469_bib19","first-page":"131","article-title":"Mefloquine blockade of Pannexin1 currents: resolution of a conflict","volume":"16","author":"Iglesias","year":"2009","journal-title":"Cell Commun. Adhes."},{"issue":"3","key":"10.1016\/j.mtbio.2022.100469_bib20","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000501278","article-title":"Pannexins in acute kidney injury","volume":"143","author":"Poudel","year":"2019","journal-title":"Nephron"},{"issue":"10","key":"10.1016\/j.mtbio.2022.100469_bib21","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2019101638","article-title":"Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly","volume":"38","author":"Chen","year":"2019","journal-title":"EMBO J."},{"issue":"3","key":"10.1016\/j.mtbio.2022.100469_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/10408444.2021.1901258","article-title":"Review of the mechanism underlying mefloquine-induced neurotoxicity","volume":"51","author":"Martins","year":"2021","journal-title":"Crit. Rev. Toxicol."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib23","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s40120-016-0045-5","article-title":"Neuropsychiatric adverse reactions to mefloquine: a systematic comparison of prescribing and patient safety guidance in the US, UK, Ireland, Australia, New Zealand, and Canada","volume":"5","author":"Nevin","year":"2016","journal-title":"Neurol. Ther."},{"key":"10.1016\/j.mtbio.2022.100469_bib24","first-page":"2997","article-title":"Advances in drug delivery via electrospun and electrosprayed nanomaterials","volume":"8","author":"Zamani","year":"2013","journal-title":"Int. J. Nanomed."},{"issue":"9","key":"10.1016\/j.mtbio.2022.100469_bib25","doi-asserted-by":"crossref","first-page":"5746","DOI":"10.1039\/C9CS00839J","article-title":"Stimuli-responsive nanobubbles for biomedical applications","volume":"50","author":"Xiong","year":"2021","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib26","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jobab.2020.03.003","article-title":"Utilization of discarded crop straw to produce cellulose nanofibrils and their assemblies","volume":"5","author":"Miao","year":"2020","journal-title":"J.\u00a0Bioresourc. Bioprod."},{"key":"10.1016\/j.mtbio.2022.100469_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.seppur.2021.119623","article-title":"Bio-based electrospun nanofiber as building blocks for a novel eco-friendly air filtration membrane: a review","volume":"277","author":"Deng","year":"2021","journal-title":"Separ. Purif. Technol."},{"issue":"11","key":"10.1016\/j.mtbio.2022.100469_bib28","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/s41565-021-00976-3","article-title":"Photothermal nanofibres enable safe engineering of therapeutic cells","volume":"16","author":"Xiong","year":"2021","journal-title":"Nat. Nanotechnol."},{"issue":"12","key":"10.1016\/j.mtbio.2022.100469_bib29","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.1039\/D1MH01199E","article-title":"An autonomously ultrafast self-healing, highly colourless, tear-resistant and compliant elastomer tailored for transparent electromagnetic interference shielding films integrated in flexible and optical electronics","volume":"8","author":"Sun","year":"2021","journal-title":"Mater. Horiz."},{"issue":"Pt B","key":"10.1016\/j.mtbio.2022.100469_bib30","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.jcis.2020.08.075","article-title":"Flexible and transparent composite nanofibre membrane that was fabricated via a \"green\" electrospinning method for efficient particulate matter 2.5 capture","volume":"582","author":"Cui","year":"2021","journal-title":"J.\u00a0Colloid Interface Sci."},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib31","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.jobab.2021.04.004","article-title":"Extraction and characterization of myofibrillar proteins from different meat sources: a comparative study","volume":"6","author":"Dara","year":"2021","journal-title":"J.\u00a0Bioresourc. Bioprod."},{"issue":"17","key":"10.1016\/j.mtbio.2022.100469_bib32","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1039\/D1TB00217A","article-title":"Magnesium oxide-incorporated electrospun membranes inhibit bacterial infections and promote the healing process of infected wounds","volume":"9","author":"Liu","year":"2021","journal-title":"J.\u00a0Mater. Chem. B"},{"key":"10.1016\/j.mtbio.2022.100469_bib33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.actbio.2020.03.044","article-title":"A\u00a0biodegradable multifunctional nanofibrous membrane for periodontal tissue regeneration","volume":"108","author":"Liu","year":"2020","journal-title":"Acta Biomater."},{"issue":"11","key":"10.1016\/j.mtbio.2022.100469_bib34","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1053\/crad.2002.1071","article-title":"MRI of the post-discectomy lumbar spine","volume":"57","author":"Babar","year":"2002","journal-title":"Clin. Radiol."},{"key":"10.1016\/j.mtbio.2022.100469_bib35","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00586-004-0801-6","article-title":"The role of closed-suction drainage in preventing epidural fibrosis and its correlation with a new grading system of epidural fibrosis on the basis of MRI","volume":"14","author":"Sen","year":"2005","journal-title":"Eur. Spine J. : Off. Publ. Eur. Spine Soc. Eur. Spinal Deformity Soc. Eur. Sec. Cerv. Spine Res. Soc."},{"issue":"11","key":"10.1016\/j.mtbio.2022.100469_bib36","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1007\/s00256-020-03488-8","article-title":"Differentiating epidural fibrosis from disc herniation on contrast-enhanced and unenhanced MRI in the postoperative lumbar spine","volume":"49","author":"Passavanti","year":"2020","journal-title":"Skeletal Radiol."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib37","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2217\/nnm.13.42","article-title":"Biodegradable poly([D,L]-lactide-co-glycolide) nanofibers for the sustainable delivery of lidocaine into the epidural space after laminectomy","volume":"9","author":"Tseng","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.mtbio.2022.100469_bib38","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s005860000144","article-title":"Relationships between epidural fibrosis, pain, disability, and psychological factors after lumbar disc surgery","volume":"9","author":"Coskun","year":"2000","journal-title":"Eur. Spine J. : Off. Publ. Eur. Spine Soc. Eur. Spinal Deformity Soc. Eur. Sec. Cerv. Spine Res. Soc."},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib39","first-page":"274","article-title":"Evaluation of the effect of vortioxetine on pain threshold by hot-plate test in mice","volume":"58","author":"Inaltekin","year":"2021","journal-title":"Noro. Psikiyatr. Ars."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib40","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s10194-018-0836-4","article-title":"PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord","volume":"19","author":"Wang","year":"2018","journal-title":"J.\u00a0Headache Pain"},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib41","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","article-title":"Quantitative assessment of tactile allodynia in the rat paw","volume":"53","author":"Chaplan","year":"1994","journal-title":"J.\u00a0Neurosci. Methods"},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib42","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s13018-016-0443-5","article-title":"The effect of suramin on inhibiting fibroblast proliferation and preventing epidural fibrosis after laminectomy in rats","volume":"11","author":"Dai","year":"2016","journal-title":"J.\u00a0Orthop. Surg. Res."},{"key":"10.1016\/j.mtbio.2022.100469_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119045","article-title":"MICAL2 regulates myofibroblasts differentiation in epidural fibrosis via SRF\/MRTF-A signaling pathway","volume":"269","author":"Jiang","year":"2021","journal-title":"Life Sci."},{"issue":"8","key":"10.1016\/j.mtbio.2022.100469_bib44","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.7150\/ijms.43986","article-title":"Fibroblast proliferation and migration in wound healing by phytochemicals: evidence for a novel synergic outcome","volume":"17","author":"Addis","year":"2020","journal-title":"Int. J. Med. Sci."},{"key":"10.1016\/j.mtbio.2022.100469_bib45","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/bs.ctdb.2018.02.004","article-title":"Collagen fibril assembly and function","volume":"130","author":"Holmes","year":"2018","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.mtbio.2022.100469_bib46","doi-asserted-by":"crossref","first-page":"e941","DOI":"10.1016\/j.wneu.2018.01.004","article-title":"Histopathologic analysis of tamoxifen on epidural fibrosis","volume":"111","author":"Ozturk","year":"2018","journal-title":"World Neurosurg."},{"issue":"15","key":"10.1016\/j.mtbio.2022.100469_bib47","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1091\/mbc.e10-01-0049","article-title":"Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in d orsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain","volume":"21","author":"Nakanishi","year":"2010","journal-title":"Mol. Biol. Cell"},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib48","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/86001","article-title":"Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-de ficient mice","volume":"4","author":"Salmon","year":"2001","journal-title":"Nat. Neurosci."},{"issue":"6","key":"10.1016\/j.mtbio.2022.100469_bib49","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.cell.2018.07.046","article-title":"The THO complex coordinates transcripts for synapse development and dopamine neuron survival","volume":"174","author":"Maeder","year":"2018","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.mtbio.2022.100469_bib50","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0166-2236(99)01500-3","article-title":"Is CREB a key to neuronal survival?","volume":"23","author":"Walton","year":"2000","journal-title":"Trends Neurosci."},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib51","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.3892\/mmr.2014.3028","article-title":"Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia","volume":"11","author":"Cheng","year":"2015","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib52","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.bbr.2011.07.020","article-title":"Learning influence on the behavioral structure of rat response to pain in hot-plate","volume":"225","author":"Casarrubea","year":"2011","journal-title":"Behav. Brain Res."},{"issue":"7","key":"10.1016\/j.mtbio.2022.100469_bib53","first-page":"616","article-title":"Efficacy of inhaled cannabis on painful diabetic neuropathy","volume":"16","author":"Wallace","year":"2015","journal-title":"J.\u00a0Pain"},{"issue":"3","key":"10.1016\/j.mtbio.2022.100469_bib54","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00109-013-1007-3","article-title":"Inflammation and oxidative stress in angiogenesis and vascular disease","volume":"91","author":"Kim","year":"2013","journal-title":"J.\u00a0Mol. Med. (Berl.)"},{"issue":"3","key":"10.1016\/j.mtbio.2022.100469_bib55","doi-asserted-by":"crossref","first-page":"377","DOI":"10.4254\/wjh.v7.i3.377","article-title":"Angiogenesis and liver fibrosis[J]","volume":"7","author":"Elpek","year":"2015","journal-title":"World J. Hepatol."},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib56","doi-asserted-by":"crossref","first-page":"218","DOI":"10.4103\/2319-4170.117894","article-title":"Anti-adhesive effect of hyaluronate in a rabbit laminectomy model","volume":"37","author":"Chen","year":"2014","journal-title":"Biomed. J."},{"issue":"1","key":"10.1016\/j.mtbio.2022.100469_bib57","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3171\/2014.10.SPINE131147","article-title":"Effects of cross-linked high-molecular-weight hyaluronic acid on epidural fibrosis: experimental study","volume":"22","author":"Is\u0131k","year":"2015","journal-title":"J.\u00a0Neurosurg. Spine"},{"issue":"6","key":"10.1016\/j.mtbio.2022.100469_bib58","doi-asserted-by":"crossref","first-page":"G1324","DOI":"10.1152\/ajpgi.90564.2008","article-title":"Interleukin-1 participates in the progression from liver injury to fibrosis","volume":"296","author":"Gieling","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"11","key":"10.1016\/j.mtbio.2022.100469_bib59","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1007\/s00204-013-1063-z","article-title":"Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL\/6 mice","volume":"87","author":"Guo","year":"2013","journal-title":"Arch. Toxicol."},{"issue":"10","key":"10.1016\/j.mtbio.2022.100469_bib60","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1093\/ndt\/gfp214","article-title":"IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis[J]","volume":"24","author":"Jones","year":"2009","journal-title":"Nephrol. Dial. Transplant."},{"issue":"5963","key":"10.1016\/j.mtbio.2022.100469_bib61","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1126\/science.1184003","article-title":"The NLRP3 inflammasome: a sensor for metabolic danger?","volume":"327","author":"Schroder","year":"2010","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.mtbio.2022.100469_bib62","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41577-019-0165-0","article-title":"The NLRP3 inflammasome: molecular activation and regulation to therapeutics","volume":"19","author":"Swanson","year":"2019","journal-title":"Nat. Rev. Immunol."},{"issue":"2","key":"10.1016\/j.mtbio.2022.100469_bib63","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/eji.201948254","article-title":"Pannexin-1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation","volume":"50","author":"Chen","year":"2020","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.mtbio.2022.100469_bib64","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jconrel.2017.06.020","article-title":"Advances in biomaterials for preventing tissue adhesion","volume":"261","author":"Wu","year":"2017","journal-title":"J.\u00a0Contr. Release : Off. J. Contr. Release Soc."},{"key":"10.1016\/j.mtbio.2022.100469_bib65","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jot.2018.02.001","article-title":"Update on biomaterials for prevention of epidural adhesion after lumbar laminectomy","volume":"13","author":"Wang","year":"2018","journal-title":"J.\u00a0Orthop. Translat."},{"issue":"4","key":"10.1016\/j.mtbio.2022.100469_bib66","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.jobab.2021.04.008","article-title":"Antioxidant and cytotoxic activities of A novel isomeric molecule (PF5) obtained from methanolic extract of pleurotus Florida mushroom","volume":"6","author":"Menaga","year":"2021","journal-title":"J.\u00a0Bioresourc. Bioprod."},{"key":"10.1016\/j.mtbio.2022.100469_bib67","first-page":"76","article-title":"Applications of PLA in modern medicine","volume":"1","author":"Destefano","year":"2020","journal-title":"Eng. Regener."},{"issue":"2","key":"10.1016\/j.mtbio.2022.100469_bib68","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1046\/j.1533-2500.2002.02012.x","article-title":"Differential diagnosis and management of spinal nerve root-related pain","volume":"2","author":"Sizer","year":"2002","journal-title":"Pain Pract."},{"issue":"Suppl 1","key":"10.1016\/j.mtbio.2022.100469_bib69","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1007\/BF00298565","article-title":"Role of peridural fibrosis in the failed back: a review","volume":"5","author":"Robertson","year":"1996","journal-title":"Eur. Spine J."},{"issue":"14","key":"10.1016\/j.mtbio.2022.100469_bib70","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.addr.2006.09.009","article-title":"Multifunctional nanocarriers","volume":"58","author":"Torchilin","year":"2006","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"16","key":"10.1016\/j.mtbio.2022.100469_bib71","doi-asserted-by":"crossref","first-page":"4043","DOI":"10.1021\/ie504452j","article-title":"Emergence and utility of nonspherical particles in biomedicine","volume":"54","author":"Fish","year":"2015","journal-title":"Ind. Eng. Chem. Res."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006422002678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006422002678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:19:36Z","timestamp":1762906776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006422002678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":71,"alternative-id":["S2590006422002678"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2022.100469","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Continuous release of mefloquine featured in electrospun fiber membranes alleviates epidural fibrosis and aids in sensory neurological function after lumbar laminectomy","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2022.100469","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100469"}}