{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T20:37:33Z","timestamp":1762634253884,"version":"build-2065373602"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T00:00:00Z","timestamp":1742688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22377014"],"award-info":[{"award-number":["22377014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.mtbio.2025.101705","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T01:32:54Z","timestamp":1742952774000},"page":"101705","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["A cerium nanocluster for effective alleviation of inflammatory bowel disease by scavenging RONS and regulating gut microbiome"],"prefix":"10.1016","volume":"32","author":[{"given":"Dan","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9823-6497","authenticated-orcid":false,"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufeng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiguo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiping","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0307-3494","authenticated-orcid":false,"given":"Hong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mtbio.2025.101705_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejps.2020.105550","article-title":"Recent advances in inflammatory bowel disease therapy","volume":"155","author":"Binienda","year":"2020","journal-title":"Eur. J. Pharmaceut. Sci."},{"issue":"10133","key":"10.1016\/j.mtbio.2025.101705_bib2","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1016\/S0140-6736(18)30458-6","article-title":"Pathology and laboratory medicine in low-income and middle-income countries 1: access to pathology and laboratory medicine services: a crucial gap","volume":"391","author":"Wilson","year":"2018","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.mtbio.2025.101705_bib3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.25122\/jml-2018-0075","article-title":"A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease","volume":"12","author":"Seyedian","year":"2019","journal-title":"J. Med. Life."},{"issue":"10","key":"10.1016\/j.mtbio.2025.101705_bib4","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.7150\/thno.33727","article-title":"Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease","volume":"9","author":"Zhao","year":"2019","journal-title":"Theranostics"},{"issue":"11","key":"10.1016\/j.mtbio.2025.101705_bib5","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.3109\/10715762.2012.717692","article-title":"Oxidative stress in ulcerative colitis: an old concept but a new concern","volume":"46","author":"Jena","year":"2012","journal-title":"Free Radic. Res."},{"issue":"7","key":"10.1016\/j.mtbio.2025.101705_bib6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00210-014-0985-1","article-title":"Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases","volume":"387","author":"Piechota-Polanczyk","year":"2014","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"2","key":"10.1016\/j.mtbio.2025.101705_bib7","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/med.21330","article-title":"Redox regulation of inflammation: old elements, a new story","volume":"35","author":"Lei","year":"2015","journal-title":"Med. Res. Rev."},{"issue":"5","key":"10.1016\/j.mtbio.2025.101705_bib8","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nchembio.85","article-title":"Reconciling the chemistry and biology of reactive oxygen species","volume":"4","author":"Winterbourn","year":"2008","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.mtbio.2025.101705_bib9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.biomaterials.2014.11.016","article-title":"ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease","volume":"41","author":"Poole","year":"2015","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.mtbio.2025.101705_bib10","first-page":"579","article-title":"Inflammation and malnutrition in inflammatory bowel disease","volume":"8","author":"Massironi","year":"2023","journal-title":"Lancet Gastroenterol"},{"issue":"6","key":"10.1016\/j.mtbio.2025.101705_bib11","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2013.10.046","article-title":"American Gastroenterological Association Institute technical review on the use of thiopurines, methotrexate, and anti-TNF-\u03b1 biologic drugs for the induction and maintenance of remission in inflammatory Crohn's disease","volume":"145","author":"Dassopoulos","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mtbio.2025.101705_bib12","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.biomaterials.2016.08.010","article-title":"A superoxide dismutase\/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease","volume":"105","author":"Zhang","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2025.101705_bib13","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.biomaterials.2015.03.037","article-title":"Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer","volume":"55","author":"Vong","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2025.101705_bib14","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.addr.2018.06.021","article-title":"Bioresponsive drug delivery systems in intestinal inflammation: state-of-the-art and future perspectives","volume":"146","author":"Kotla","year":"2019","journal-title":"Adv. Drug Delivery. Rev."},{"issue":"3","key":"10.1016\/j.mtbio.2025.101705_bib15","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.nano.2018.01.003","article-title":"pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via selective accumulation in inflamed colon regions","volume":"14","author":"Naeem","year":"2018","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"8","key":"10.1016\/j.mtbio.2025.101705_bib16","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1016\/j.nano.2015.07.003","article-title":"Nanomedicine in the ROS-mediated pathophysiology: applications and clinical advances","volume":"11","author":"Nash","year":"2015","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"15","key":"10.1016\/j.mtbio.2025.101705_bib17","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.2217\/nnm-2018-0415","article-title":"Glycyrrhizic acid-loaded pH-sensitive poly-(lactic-co-glycolic acid) nanoparticles for the amelioration of inflammatory bowel disease","volume":"14","author":"Zeeshan","year":"2019","journal-title":"Nanomed"},{"issue":"2","key":"10.1016\/j.mtbio.2025.101705_bib18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.bpg.2010.01.002","article-title":"Adverse effects of biologics used for treating IBD","volume":"24","author":"Stallmach","year":"2010","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"issue":"10","key":"10.1016\/j.mtbio.2025.101705_bib19","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1007\/s12274-018-2092-y","article-title":"Scavenging of reactive oxygen and nitrogen species with nanomaterials","volume":"11","author":"Ferreira","year":"2018","journal-title":"Nano Res."},{"key":"10.1016\/j.mtbio.2025.101705_bib20","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jconrel.2023.09.033","article-title":"Recent advances on emerging nanomaterials for diagnosis and treatment of inflammatory bowel disease","volume":"363","author":"Fu","year":"2023","journal-title":"J. Control. Release."},{"issue":"34","key":"10.1016\/j.mtbio.2025.101705_bib21","doi-asserted-by":"crossref","first-page":"19086","DOI":"10.1021\/jacs.3c07048","article-title":"Intrinsic strain-mediated ultrathin ceria nanoantioxidant","volume":"145","author":"Liu","year":"2023","journal-title":"J. Am. Chem. Soc."},{"issue":"18","key":"10.1016\/j.mtbio.2025.101705_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202400048","article-title":"2D is better: engineering polydopamine into cationic nanosheets to enhance anti-inflammatory capability","volume":"13","author":"Liu","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"19","key":"10.1016\/j.mtbio.2025.101705_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202207350","article-title":"Oral metal-free melanin nanozymes for natural and durable targeted treatment of inflammatory bowel disease (IBD)","volume":"19","author":"Huang","year":"2023","journal-title":"Small"},{"issue":"4","key":"10.1016\/j.mtbio.2025.101705_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abj2372","article-title":"A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease","volume":"8","author":"Shi","year":"2022","journal-title":"Sci. Adv."},{"issue":"2","key":"10.1016\/j.mtbio.2025.101705_bib25","doi-asserted-by":"crossref","first-page":"582","DOI":"10.3748\/wjg.v22.i2.582","article-title":"Insight to drug delivery aspects for colorectal cancer","volume":"22","author":"Gulbake","year":"2016","journal-title":"World J. Gastroenterol."},{"issue":"6","key":"10.1016\/j.mtbio.2025.101705_bib26","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1039\/C4EN00052H","article-title":"Behavior of nanoceria in biologically-relevant environments","volume":"1","author":"Kumar","year":"2014","journal-title":"Environ. Sci. Nano"},{"issue":"1","key":"10.1016\/j.mtbio.2025.101705_bib27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12951-022-01319-7","article-title":"A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease","volume":"20","author":"Zeng","year":"2022","journal-title":"J. Nanobiotechnol."},{"issue":"6","key":"10.1016\/j.mtbio.2025.101705_bib28","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.inoche.2010.03.050","article-title":"A hexanuclear cerium(IV) cluster with mixed coordination environment","volume":"13","author":"Das","year":"2010","journal-title":"Inorg. Chem. Commun."},{"issue":"10","key":"10.1016\/j.mtbio.2025.101705_bib29","doi-asserted-by":"crossref","first-page":"5429","DOI":"10.1002\/anie.202013904","article-title":"Hierarchical self-assembly of discrete metal-organic cages into supramolecular nanoparticles for intracellular protein delivery","volume":"60","author":"Liu","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"issue":"51","key":"10.1016\/j.mtbio.2025.101705_bib30","doi-asserted-by":"crossref","first-page":"26740","DOI":"10.1002\/anie.202111213","article-title":"Tetraphenylethylene-featured fluorescent supramolecular nanoparticles for intracellular trafficking of protein delivery and neuroprotection","volume":"60","author":"Liu","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"issue":"9","key":"10.1016\/j.mtbio.2025.101705_bib31","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.jpcs.2012.05.009","article-title":"Wet chemical synthesis and characterization of pure and cerium doped Dy2O3 nanoparticles","volume":"73","author":"Krishna Chandar","year":"2012","journal-title":"J. Phys. Chem. Solids."},{"issue":"9","key":"10.1016\/j.mtbio.2025.101705_bib32","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1039\/C4SM02339K","article-title":"An easy approach for constructing vesicles by using aromatic molecules with \u03b2-cyclodextrin","volume":"11","author":"Li","year":"2015","journal-title":"Soft Matter"},{"issue":"9","key":"10.1016\/j.mtbio.2025.101705_bib33","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.3390\/bioengineering10091088","article-title":"Guar-based injectable hydrogel for drug delivery and in vitro bone cell growth","volume":"10","author":"Poudel","year":"2023","journal-title":"Bioengineering"},{"issue":"9","key":"10.1016\/j.mtbio.2025.101705_bib34","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1039\/C4SM02339K","article-title":"An easy approach for constructing vesicles by using aromatic molecules with \u03b2-cyclodextrin","volume":"11","author":"Li","year":"2015","journal-title":"Soft Matter"},{"issue":"1","key":"10.1016\/j.mtbio.2025.101705_bib35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3390\/polym11010071","article-title":"Preparation of \u03b2-cyclodextrin inclusion complex and its application as an intumescent flame retardant for epoxy","volume":"11","author":"Shan","year":"2019","journal-title":"Polymers"},{"issue":"5","key":"10.1016\/j.mtbio.2025.101705_bib36","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1021\/acsnano.2c09127","article-title":"Redox homeostasis strategy for inflammatory macrophage reprogramming in rheumatoid arthritis based on ceria oxide nanozyme-complexed biopolymeric micelles","volume":"17","author":"Zhou","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2025.101705_bib37","doi-asserted-by":"crossref","first-page":"682","DOI":"10.3389\/fchem.2020.00682","article-title":"Cerium oxide-decorated \u03b3-Fe2O3 nanoparticles: design, synthesis and in vivo effects on parameters of oxidative stress","volume":"8","author":"Moskvin","year":"2020","journal-title":"Front. Chem."},{"issue":"2","key":"10.1016\/j.mtbio.2025.101705_bib38","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1021\/acs.inorgchem.5b02473","article-title":"Coordination-driven self-assembly of a 2D graphite-like framework constructed from high-nuclear Ce10 cluster encapsulated polyoxotungstates","volume":"55","author":"Ma","year":"2016","journal-title":"Inorg. Chem."},{"issue":"1","key":"10.1016\/j.mtbio.2025.101705_bib39","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1038\/s41467-021-21714-2","article-title":"Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics","volume":"12","author":"Weng","year":"2021","journal-title":"Nat. Commun."},{"issue":"30","key":"10.1016\/j.mtbio.2025.101705_bib40","doi-asserted-by":"crossref","first-page":"8728","DOI":"10.1002\/anie.201503022","article-title":"Catalytically active and spectator Ce3+ in ceria-supported metal catalysts","volume":"54","author":"Kopelent","year":"2015","journal-title":"Angew. Chem. Int. Ed."},{"issue":"10","key":"10.1016\/j.mtbio.2025.101705_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202210819","article-title":"Ceria-based therapeutic antioxidants for biomedical applications","volume":"36","author":"Kim","year":"2024","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.mtbio.2025.101705_bib42","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s12951-022-01319-7","article-title":"A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease","volume":"20","author":"Zeng","year":"2022","journal-title":"J Nanobiotechnology"},{"issue":"16","key":"10.1016\/j.mtbio.2025.101705_bib43","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.3748\/wjg.v11.i16.2371","article-title":"Radical induction theory of ulcerative colitis","volume":"11","author":"Pravda","year":"2005","journal-title":"World J. Gastroenterol."},{"issue":"9","key":"10.1016\/j.mtbio.2025.101705_bib44","doi-asserted-by":"crossref","first-page":"15026","DOI":"10.1021\/acsnano.2c06151","article-title":"Ultrathin hafnium disulfide atomic crystals with ROS-scavenging and colon-targeting capabilities for inflammatory bowel disease treatment","volume":"16","author":"Li","year":"2022","journal-title":"ACS Nano"},{"issue":"14","key":"10.1016\/j.mtbio.2025.101705_bib45","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202308092","article-title":"H2S\u2010Releasing versatile montmorillonite nanoformulation trilogically renovates the gut microenvironment for inflammatory bowel disease modulation","volume":"11","author":"Jin","year":"2024","journal-title":"Adv. Sci."},{"issue":"7","key":"10.1016\/j.mtbio.2025.101705_bib46","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00011-021-01482-x","article-title":"Targeting JAK\/STAT signaling pathways in treatment of inflammatory bowel disease","volume":"70","author":"Wang","year":"2021","journal-title":"Inflamm. Res."},{"issue":"1","key":"10.1016\/j.mtbio.2025.101705_bib47","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/eji.200838316","article-title":"The role of MAPK in governing lymphocyte adhesion to and migration across the microvasculature in inflammatory bowel disease","volume":"39","author":"Scaldaferri","year":"2009","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.mtbio.2025.101705_bib48","article-title":"MK2 is required for neutrophil-derived ROS production and inflammatory bowel disease","volume":"7","author":"Zhang","year":"2020","journal-title":"Front. Med."},{"issue":"37","key":"10.1016\/j.mtbio.2025.101705_bib49","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abp9882","article-title":"Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy","volume":"8","author":"Zhang","year":"2022","journal-title":"Sci. Adv."},{"issue":"7","key":"10.1016\/j.mtbio.2025.101705_bib50","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/s41577-019-0268-7","article-title":"Host\u2013microbiota interactions in inflammatory bowel disease","volume":"20","author":"Caruso","year":"2020","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.mtbio.2025.101705_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13099-019-0341-6","article-title":"Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels","volume":"12","author":"Alam","year":"2020","journal-title":"Gut Pathog."},{"issue":"6120","key":"10.1016\/j.mtbio.2025.101705_bib52","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1126\/science.1232467","article-title":"Host-derived nitrate boosts growth of E. coli in the inflamed gut","volume":"339","author":"Winter","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2025.101705_bib53","first-page":"167","article-title":"Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease","volume":"35","author":"Shi","year":"2024","journal-title":"Bioact. Mater."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006425002649?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006425002649?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T20:34:59Z","timestamp":1762634099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006425002649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":53,"alternative-id":["S2590006425002649"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.101705","relation":{},"ISSN":["2590-0064"],"issn-type":[{"type":"print","value":"2590-0064"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A cerium nanocluster for effective alleviation of inflammatory bowel disease by scavenging RONS and regulating gut microbiome","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.101705","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101705"}}