{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:01:28Z","timestamp":1787011288676,"version":"build-2736575974"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:00:00Z","timestamp":1750896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271914"],"award-info":[{"award-number":["82271914"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371216"],"award-info":[{"award-number":["82371216"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271228"],"award-info":[{"award-number":["32271228"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LZ25H090002"],"award-info":[{"award-number":["LZ25H090002"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005054","name":"Nantong University","doi-asserted-by":"publisher","award":["KFJN2509"],"award-info":[{"award-number":["KFJN2509"]}],"id":[{"id":"10.13039\/501100005054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.mtbio.2025.102025","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T19:21:26Z","timestamp":1750965686000},"page":"102025","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Dorsal root ganglion-targeted analgesic delivery for effective relief of neuropathic pain"],"prefix":"10.1016","volume":"33","author":[{"given":"Jiajia","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baochun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3344-1449","authenticated-orcid":false,"given":"Zhongping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mtbio.2025.102025_bib1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.neuron.2006.09.021","article-title":"Mechanisms of neuropathic pain","volume":"52","author":"Campbell","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.mtbio.2025.102025_bib2","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S1474-4422(10)70143-5","article-title":"Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment","volume":"9","author":"Baron","year":"2010","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.mtbio.2025.102025_bib3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.bja.2023.04.021","article-title":"Advances and challenges in neuropathic pain: a narrative review and future directions","volume":"131","author":"Attal","year":"2023","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.mtbio.2025.102025_bib4","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev-pharmtox-051421-112259","article-title":"Neuropathic pain: mechanisms, sex differences, and potential therapies for a global problem","volume":"63","author":"Ghazisaeidi","year":"2023","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.mtbio.2025.102025_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108546","article-title":"Neuropathic pain: from actual pharmacological treatments to new therapeutic horizons","volume":"251","author":"Thouaye","year":"2023","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.mtbio.2025.102025_bib6","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3390\/biomedicines12010204","article-title":"A literature review: the mechanisms and treatment of neuropathic pain\u2014A brief discussion","volume":"12","author":"Rugnath","year":"2024","journal-title":"Biomedicines"},{"key":"10.1016\/j.mtbio.2025.102025_bib7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(14)70251-0","article-title":"Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis","volume":"14","author":"Finnerup","year":"2015","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.mtbio.2025.102025_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2023.105401","article-title":"A systematic review and meta-analysis of neuropathic pain in multiple sclerosis: prevalence, clinical types, sex dimorphism, and increased depression and anxiety symptoms","volume":"154","author":"Rodrigues","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.mtbio.2025.102025_bib9","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jconrel.2024.10.036","article-title":"The long road of drug development for endometriosis \u2013 pains, gains, and hopes","volume":"376","author":"Liao","year":"2024","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2025.102025_bib10","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1002\/ejp.2120","article-title":"Personalized treatment of neuropathic pain: where are we now?","volume":"27","author":"Bouhassira","year":"2023","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.mtbio.2025.102025_bib11","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.3390\/pharmaceutics15092309","article-title":"Nanomaterial-based drug delivery systems for pain treatment and relief: from the delivery of a single drug to Co-Delivery of multiple therapeutics","volume":"15","author":"Xu","year":"2023","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.mtbio.2025.102025_bib12","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.2147\/IJN.S400798","article-title":"Sustained-release esketamine based nanoparticle-hydrogel delivery system for neuropathic pain management","author":"Zhang","year":"2023","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.mtbio.2025.102025_bib13","article-title":"Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications","volume":"30","author":"Li","year":"2025","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.mtbio.2025.102025_bib14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.tips.2021.03.007","article-title":"Nanotherapeutic-directed approaches to analgesia","volume":"42","author":"Mazaleuskaya","year":"2021","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.mtbio.2025.102025_bib15","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1007\/s40140-024-00649-6","article-title":"Exparel and beyond: novel local anesthetics, where we are and what is coming up","volume":"14","author":"Syed","year":"2024","journal-title":"Curr. Anesthesiol. Rep."},{"key":"10.1016\/j.mtbio.2025.102025_bib16","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/ALN.0000000000003658","article-title":"Liposomal bupivacaine: effective, cost-effective, or (Just) costly?","volume":"134","author":"McCann","year":"2021","journal-title":"Anesthesiology"},{"key":"10.1016\/j.mtbio.2025.102025_bib17","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/ALN.0000000000004988","article-title":"Liposomal bupivacaine for peripheral nerve blockade: a randomized, controlled, crossover, triple-blinded pharmacodynamic study in volunteers","volume":"141","author":"Zadrazil","year":"2024","journal-title":"Anesthesiology"},{"key":"10.1016\/j.mtbio.2025.102025_bib18","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1213\/01.ANE.0000145009.03574.78","article-title":"A comparison of depodur\u2122, a novel, single-dose extended-release epidural morphine, with standard epidural morphine for pain relief after lower abdominal surgery","volume":"100","author":"Gambling","year":"2005","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mtbio.2025.102025_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101223","article-title":"Nanotechnology for pain management: current and future therapeutic interventions","volume":"39","author":"Bhansali","year":"2021","journal-title":"Nano Today"},{"key":"10.1016\/j.mtbio.2025.102025_bib20","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/s41467-019-13839-2","article-title":"Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain","volume":"11","author":"Yu","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2025.102025_bib21","article-title":"Dorsal root ganglion (DRG) and chronic pain, anesth","volume":"11","author":"Berger","year":"2021","journal-title":"Pain Med."},{"key":"10.1016\/j.mtbio.2025.102025_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116427","article-title":"TFAP2A is involved in neuropathic pain by regulating Grin1 expression in glial cells of the dorsal root ganglion","volume":"227","author":"Yuan","year":"2024","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.mtbio.2025.102025_bib23","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jconrel.2025.01.028","article-title":"Ropivacaine and celecoxib-loaded injectable composite hydrogel for improved chronic pain-exacerbated myocardial ischemia-reperfusion injury","volume":"379","author":"Wu","year":"2025","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2025.102025_bib24","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4103\/1673-5374.374655","article-title":"The dorsal root ganglion as a target for neurorestoration in neuropathic pain","volume":"19","author":"Estivill-Torr\u00fas","year":"2024","journal-title":"Neural. Regen. Res."},{"key":"10.1016\/j.mtbio.2025.102025_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1130823","article-title":"The versatile roles of ADAM8 in cancer cell migration, mechanics, and extracellular matrix remodeling","volume":"11","author":"Mierke","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.mtbio.2025.102025_bib26","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.ejpb.2010.01.002","article-title":"Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: in vitro and in vivo studies","volume":"74","author":"Zhang","year":"2010","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.mtbio.2025.102025_bib27","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jconrel.2021.04.035","article-title":"Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer","volume":"334","author":"Long","year":"2021","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2025.102025_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.153171","article-title":"Organ-selective lipid nanoparticles for precise cancer therapy: beyond liposomes and polymeric micelles","volume":"494","author":"Huang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.mtbio.2025.102025_bib29","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.jconrel.2023.03.052","article-title":"On the mechanism of tissue-selective gene delivery by lipid nanoparticles","volume":"362","author":"Kimura","year":"2023","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2025.102025_bib30","article-title":"Nerve injury-induced \u03b3H2AX reduction in primary sensory neurons is involved in neuropathic pain processing","volume":"24","author":"Zhang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mtbio.2025.102025_bib31","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1038\/s41401-024-01301-z","article-title":"Desloratadine ameliorates paclitaxel-induced peripheral neuropathy and hypersensitivity reactions in mice","volume":"45","author":"Lu","year":"2024","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.mtbio.2025.102025_bib32","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adi1564","article-title":"Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons","volume":"16","author":"Jiang","year":"2024","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.mtbio.2025.102025_bib33","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/s42003-025-07506-0","article-title":"An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cord","volume":"8","author":"Dong","year":"2025","journal-title":"Commun. Biol."},{"key":"10.1016\/j.mtbio.2025.102025_bib34","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1146\/annurev.pa.20.040180.002301","article-title":"Efficient analysis of experimental observations","volume":"20","author":"Dixon","year":"1980","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.mtbio.2025.102025_bib35","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","article-title":"A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia","volume":"32","author":"Hargreaves","year":"1988","journal-title":"Pain"},{"key":"10.1016\/j.mtbio.2025.102025_bib36","article-title":"A simple nanoplatform of thermo-sensitive liposomes and gold nanorods to treat bone metastasis through improved chemotherapy combined with photothermal therapy","volume":"X 8","author":"Gu","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.mtbio.2025.102025_bib37","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s12974-024-03160-1","article-title":"Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signaling","volume":"21","author":"Ni","year":"2024","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.mtbio.2025.102025_bib38","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.brainresbull.2009.02.008","article-title":"Attenuating effects of testosterone on depressive-like behavior in the forced swim test in healthy male rats","volume":"79","author":"Buddenberg","year":"2009","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.mtbio.2025.102025_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.703715","article-title":"Peptide-based inhibitors of ADAM and ADAMTS metalloproteinases","volume":"8","author":"Pluda","year":"2021","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.mtbio.2025.102025_bib40","doi-asserted-by":"crossref","DOI":"10.1021\/acsnano.2c11904","article-title":"Insights into the structure of comirnaty Covid-19 vaccine: a theory on soft, partially bilayer-covered nanoparticles with hydrogen bond-stabilized mRNA-Lipid complexes","volume":"17","author":"Szebeni","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2025.102025_bib41","article-title":"Design, optimization, and evaluation of lyophilized lipid nanoparticles for mRNA-based pulmonary mucosal vaccination","volume":"32","author":"Lu","year":"2025","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.mtbio.2025.102025_bib42","doi-asserted-by":"crossref","first-page":"14e1","DOI":"10.1016\/j.pain.2005.10.036","article-title":"Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse","volume":"122","author":"Bourquin","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.mtbio.2025.102025_bib43","doi-asserted-by":"crossref","first-page":"3343","DOI":"10.2174\/0113816128274200231128065425","article-title":"Neuropathy, its profile and experimental nerve injury neuropathic pain models: a review","volume":"29","author":"Kumar Sharma","year":"2023","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.mtbio.2025.102025_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114359","article-title":"Micro- and nanocarriers for pain alleviation","volume":"187","author":"da Silva","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.mtbio.2025.102025_bib45","doi-asserted-by":"crossref","first-page":"751","DOI":"10.3390\/biomedicines12040751","article-title":"Molecular and cellular involvement in CIPN","volume":"12","author":"Kacem","year":"2024","journal-title":"Biomedicines"},{"key":"10.1016\/j.mtbio.2025.102025_bib46","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.3390\/cancers16142571","article-title":"Chemotherapy-induced peripheral neuropathy (CIPN): a narrative review and proposed theoretical model","volume":"16","author":"Lee","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.mtbio.2025.102025_bib47","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1213\/01.ANE.0000186348.86792.38","article-title":"Systemic administration of local anesthetics to relieve neuropathic pain: a systematic review and meta-analysis","volume":"101","author":"Tremont-Lukats","year":"2005","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mtbio.2025.102025_bib48","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S1474-4422(14)70102-4","article-title":"Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms","volume":"13","author":"Jensen","year":"2014","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.mtbio.2025.102025_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2023.114417","article-title":"Evaluating pain behaviours: widely used mechanical and thermal methods in rodents","volume":"446","author":"Modi","year":"2023","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.mtbio.2025.102025_bib50","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s40122-017-0085-2","article-title":"A review of neuropathic pain: from diagnostic tests to mechanisms","volume":"6","author":"Truini","year":"2017","journal-title":"Pain Ther"},{"key":"10.1016\/j.mtbio.2025.102025_bib51","article-title":"Depression prevalence in neuropathic pain and its impact on the quality of life, pain res","volume":"2020","author":"Cherif","year":"2020","journal-title":"Manag."},{"key":"10.1016\/j.mtbio.2025.102025_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2024.105673","article-title":"Neuropathic pain, mood, and stress-related disorders: a literature review of comorbidity and co-pathogenesis","volume":"161","author":"Vieira","year":"2024","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.mtbio.2025.102025_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e14522","article-title":"Comparative analysis between open field and elevated plus maze tests as a method for evaluating anxiety-like behavior in mice","volume":"9","author":"Figueiredo Cerqueira","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.mtbio.2025.102025_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actbio.2024.04.034","article-title":"Local anesthetic delivery systems for the management of postoperative pain","volume":"181","author":"Zhao","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.mtbio.2025.102025_bib55","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1007\/s00268-015-3105-6","article-title":"Efficacy of intravenous lidocaine for postoperative analgesia following laparoscopic surgery: a meta-analysis","volume":"39","author":"Ventham","year":"2015","journal-title":"World J. Surg."},{"key":"10.1016\/j.mtbio.2025.102025_bib56","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1080\/08941939.2020.1801913","article-title":"Pre-, peri-, and postoperative intravenous ropivacaine versus that of lidocaine for analgesia after hand-assisted laparoscopic surgery of left colon cancer: a retrospective analysis","volume":"34","author":"Gu","year":"2021","journal-title":"J. Invest. Surg."},{"key":"10.1016\/j.mtbio.2025.102025_bib57","first-page":"1213","article-title":"Characteristics of ropivacaine block of Na+ channels in rat dorsal root ganglion neurons","volume":"91","author":"Oda","year":"2000","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mtbio.2025.102025_bib58","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.bja.2019.06.014","article-title":"Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review","volume":"123","author":"Hermanns","year":"2019","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.mtbio.2025.102025_bib59","article-title":"The efficacy and safety of spinal anesthesia with hyperbaric ropivacaine 0.75% and bupivacaine 0.5% in patients undergoing infra-umbilical surgeries: a randomized, double-blind study","volume":"16","author":"Kalbande","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.mtbio.2025.102025_bib60","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1001\/jama.2024.23898","article-title":"Intravenous lidocaine for gut function recovery in colonic surgery: a randomized clinical trial","volume":"333","author":"Paterson","year":"2025","journal-title":"JAMA"},{"key":"10.1016\/j.mtbio.2025.102025_bib61","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/anae.16531","article-title":"Dosing optimisation of intravenous lidocaine in patients with class 1\u20133 obesity by population pharmacokinetic analysis","volume":"80","author":"Tognolini","year":"2025","journal-title":"Anaesthesia"},{"key":"10.1016\/j.mtbio.2025.102025_bib62","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jen.2024.02.002","article-title":"Local anesthetic systemic toxicity (LAST): more common than you think","volume":"50","author":"Denke","year":"2024","journal-title":"J. Emerg. Nurs."},{"key":"10.1016\/j.mtbio.2025.102025_bib63","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1042\/CS20180906","article-title":"ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance","volume":"133","author":"Conrad","year":"2019","journal-title":"Clin. Sci."},{"key":"10.1016\/j.mtbio.2025.102025_bib64","article-title":"Cardioprotective effects of phlorizin on hyperlipidemia-induced myocardial injury: involvement of suppression in pyroptosis via regulating HK1\/NLRP3\/Caspase-1 signaling pathway","volume":"1","author":"Zhang","year":"2024","journal-title":"Appl. Biochem. Biotechnol."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006425005952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006425005952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T20:22:44Z","timestamp":1762633364000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006425005952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":64,"alternative-id":["S2590006425005952"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.102025","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dorsal root ganglion-targeted analgesic delivery for effective relief of neuropathic pain","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.102025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102025"}}