{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T12:04:40Z","timestamp":1773403480857,"version":"3.50.1"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,13]],"date-time":"2025-07-13T00:00:00Z","timestamp":1752364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004733","name":"University of Macau","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004733","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006469","name":"Fundo para o Desenvolvimento das Ci\u00eancias e da Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006469","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.mtbio.2025.102087","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T16:08:50Z","timestamp":1752595730000},"page":"102087","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Acousto-optogenetics bandpass stabilizer: A programmable platform for mapping single-cell phenotypic life trajectories"],"prefix":"10.1016","volume":"33","author":[{"given":"Yuxin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Quan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4180-8669","authenticated-orcid":false,"given":"Shizheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2084-5804","authenticated-orcid":false,"given":"Yinning","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6675","key":"10.1016\/j.mtbio.2025.102087_bib1","doi-asserted-by":"crossref","DOI":"10.1126\/science.adf8486","article-title":"Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics","volume":"382","author":"Engblom","year":"2023","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.mtbio.2025.102087_bib2","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1038\/s41573-022-00472-w","article-title":"Phenotypic drug discovery: recent successes, lessons learned and new directions","volume":"21","author":"Vincent","year":"2022","journal-title":"Nat. Rev. Drug Discov."},{"issue":"8","key":"10.1016\/j.mtbio.2025.102087_bib3","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/s41588-020-0668-4","article-title":"Characterizing the ecological and evolutionary dynamics of cancer","volume":"52","author":"Zahir","year":"2020","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.mtbio.2025.102087_bib4","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S2213-2600(21)00218-6","article-title":"The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity","volume":"9","author":"Osuchowski","year":"2021","journal-title":"Lancet Respir. Med."},{"issue":"9","key":"10.1016\/j.mtbio.2025.102087_bib5","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1038\/s41591-022-01959-0","article-title":"Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma","volume":"28","author":"Haradhvala","year":"2022","journal-title":"Nature medicine"},{"issue":"44","key":"10.1016\/j.mtbio.2025.102087_bib6","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202000496","article-title":"Engineering cell\u2010derived matrices: from 3D models to advanced personalized therapies","volume":"30","author":"Rubi\u2010Sans","year":"2020","journal-title":"Adv. Funct. Mater."},{"issue":"2","key":"10.1016\/j.mtbio.2025.102087_bib7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/s41563-020-00829-9","article-title":"Stem-cell-based embryo models for fundamental research and translation","volume":"20","author":"Fu","year":"2021","journal-title":"Nat. Mater."},{"issue":"11","key":"10.1016\/j.mtbio.2025.102087_bib8","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/s41577-020-0306-5","article-title":"A guide to cancer immunotherapy: from T cell basic science to clinical practice","volume":"20","author":"Waldman","year":"2020","journal-title":"Nat. Rev. Immunol."},{"issue":"8","key":"10.1016\/j.mtbio.2025.102087_bib9","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/s41568-021-00366-w","article-title":"Cancer stem cell\u2013immune cell crosstalk in tumour progression","volume":"21","author":"Bayik","year":"2021","journal-title":"Nat. Rev. Cancer"},{"issue":"7909","key":"10.1016\/j.mtbio.2025.102087_bib10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/s41586-022-04593-5","article-title":"Chemical reprogramming of human somatic cells to pluripotent stem cells","volume":"605","author":"Guan","year":"2022","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s12551-023-01174-2","article-title":"Integrating single-cell transcriptomics with cellular phenotypes: cell morphology, Ca2+ imaging and electrophysiology","volume":"16","author":"Camunas-Soler","year":"2024","journal-title":"Biophysical Reviews"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib12","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1038\/s41467-020-18469-7","article-title":"Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes","volume":"11","author":"Mok","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2025.102087_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.120028","article-title":"Magnetic 3D cell culture: state of the art and current advances","volume":"286","author":"Caleffi","year":"2021","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib14","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/lpor.200900044","article-title":"Neural stimulation with optical radiation","volume":"5","author":"Richter","year":"2011","journal-title":"Laser Photon. Rev."},{"issue":"5","key":"10.1016\/j.mtbio.2025.102087_bib15","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41569-020-00478-0","article-title":"Cardiac optogenetics: a decade of enlightenment","volume":"18","author":"Entcheva","year":"2021","journal-title":"Nat. Rev. Cardiol."},{"issue":"4","key":"10.1016\/j.mtbio.2025.102087_bib16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41551-021-00829-3","article-title":"Towards translational optogenetics","volume":"7","author":"Bansal","year":"2023","journal-title":"Nat. Biomed. Eng."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s43586-022-00136-4","article-title":"Optogenetics for light control of biological systems","volume":"2","author":"Emiliani","year":"2022","journal-title":"Nature Reviews Methods Primers"},{"key":"10.1016\/j.mtbio.2025.102087_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.112003","article-title":"Cellular sensing platform with enhanced sensitivity based on optogenetic modulation of cell homeostasis","volume":"154","author":"Gheorghiu","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.mtbio.2025.102087_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2022.114457","article-title":"Recent advances in cellular optogenetics for photomedicine","volume":"188","author":"Chen","year":"2022","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib20","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.tree.2023.08.014","article-title":"Beyond reaction norms: the temporal dynamics of phenotypic plasticity","volume":"39","author":"Dupont","year":"2024","journal-title":"Trends Ecol. Evol."},{"issue":"26","key":"10.1016\/j.mtbio.2025.102087_bib21","doi-asserted-by":"crossref","first-page":"E5167","DOI":"10.1073\/pnas.1703623114","article-title":"Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins","volume":"114","author":"Tkatch","year":"2017","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.mtbio.2025.102087_bib22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00249-001-0202-2","article-title":"Fluorescence photobleaching analysis for the study of cellular dynamics","volume":"31","author":"Klonis","year":"2002","journal-title":"Eur. Biophys. J."},{"issue":"12","key":"10.1016\/j.mtbio.2025.102087_bib23","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/nmeth819","article-title":"A guide to choosing fluorescent proteins","volume":"2","author":"Shaner","year":"2005","journal-title":"Nat. Methods"},{"key":"10.1016\/j.mtbio.2025.102087_bib24","doi-asserted-by":"crossref","DOI":"10.1177\/1536012120913693","article-title":"Signal to noise ratio as a cross-platform metric for intraoperative fluorescence imaging","volume":"19","author":"Gharia","year":"2020","journal-title":"Mol. Imaging"},{"issue":"13","key":"10.1016\/j.mtbio.2025.102087_bib25","doi-asserted-by":"crossref","first-page":"418A","DOI":"10.1021\/ac00109a001","article-title":"Detecting single molecules in liquids","volume":"67","author":"Barnes","year":"1995","journal-title":"Anal. Chem."},{"key":"10.1016\/j.mtbio.2025.102087_bib26","first-page":"1","article-title":"Spatial analysis by current multiplexed imaging technologies for the molecular characterisation of cancer tissues","author":"Semba","year":"2024","journal-title":"Br. J. Cancer"},{"issue":"9","key":"10.1016\/j.mtbio.2025.102087_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202101817","article-title":"Bleaching\u2010resistant super\u2010resolution fluorescence microscopy","volume":"9","author":"Kwon","year":"2022","journal-title":"Adv. Sci."},{"issue":"2","key":"10.1016\/j.mtbio.2025.102087_bib28","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/bit.27620","article-title":"A review of manufacturing capabilities of cell spheroid generation technologies and future development","volume":"118","author":"Liu","year":"2021","journal-title":"Biotechnol. Bioeng."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib29","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1038\/s41467-024-46361-1","article-title":"Deep model predictive control of gene expression in thousands of single cells","volume":"15","author":"Lugagne","year":"2024","journal-title":"Nat. Commun."},{"issue":"14","key":"10.1016\/j.mtbio.2025.102087_bib30","doi-asserted-by":"crossref","DOI":"10.1063\/1.2718503","article-title":"Bleaching and diffusion dynamics in optofluidic dye lasers","volume":"90","author":"Gersborg-Hansen","year":"2007","journal-title":"Appl. Phys. Lett."},{"issue":"3","key":"10.1016\/j.mtbio.2025.102087_bib31","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1364\/OME.8.000676","article-title":"Fluorescence enhancement of a bleach-resistant solution for use in microfluidic devices","volume":"8","author":"Saito","year":"2018","journal-title":"Opt. Mater. Express"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib32","article-title":"A coral-on-a-chip microfluidic platform enabling live-imaging microscopy of reef-building corals","volume":"7","author":"Shapiro","year":"2016","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib33","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/s41467-023-44280-1","article-title":"AI-driven projection tomography with multicore fibre-optic cell rotation","volume":"15","author":"Sun","year":"2024","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib34","doi-asserted-by":"crossref","DOI":"10.1063\/5.0039087","article-title":"Dual-fiber microfluidic chip for multimodal manipulation of single cells","volume":"15","author":"Huang","year":"2021","journal-title":"Biomicrofluidics"},{"issue":"19","key":"10.1016\/j.mtbio.2025.102087_bib35","doi-asserted-by":"crossref","first-page":"12795","DOI":"10.1021\/acs.analchem.0c02765","article-title":"Submicron particle concentration and patterning with ultralow frequency acoustic vibration","volume":"92","author":"Zhou","year":"2020","journal-title":"Analytical chemistry"},{"issue":"9","key":"10.1016\/j.mtbio.2025.102087_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/admt.202000323","article-title":"Acoustic vibration\u2010induced actuation of multiple microrotors in microfluidics","volume":"5","author":"Zhou","year":"2020","journal-title":"Advanced Materials Technologies"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib37","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/s43586-022-00109-7","article-title":"Acoustofluidics for biomedical applications","volume":"2","author":"Rufo","year":"2022","journal-title":"Nature Reviews Methods Primers"},{"issue":"15","key":"10.1016\/j.mtbio.2025.102087_bib38","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1039\/C4LC00312H","article-title":"AC electric field induced dipole-based on-chip 3D cell rotation","volume":"14","author":"Benhal","year":"2014","journal-title":"Lab Chip"},{"issue":"16","key":"10.1016\/j.mtbio.2025.102087_bib39","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1039\/C8LC00407B","article-title":"3D cell electrorotation and imaging for measuring multiple cellular biophysical properties","volume":"18","author":"Huang","year":"2018","journal-title":"Lab Chip"},{"issue":"10","key":"10.1016\/j.mtbio.2025.102087_bib40","doi-asserted-by":"crossref","DOI":"10.1063\/1.3116091","article-title":"Cell manipulation with magnetic particles toward microfluidic cytometry","volume":"105","author":"Liu","year":"2009","journal-title":"J. Appl. Phys."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib41","doi-asserted-by":"crossref","first-page":"6942","DOI":"10.1038\/s41598-017-06946-x","article-title":"Microfluidic sorting of intrinsically magnetic cells under visual control","volume":"7","author":"Myklatun","year":"2017","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.mtbio.2025.102087_bib42","article-title":"Non\u2010invasive and minute\u2010frequency 3D tomographic imaging enabling long\u2010term spatiotemporal observation of single cell fate","volume":"7","author":"Liang","year":"2023","journal-title":"Small Methods"},{"issue":"16","key":"10.1016\/j.mtbio.2025.102087_bib43","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1039\/D0LC00595A","article-title":"Ultrasonic microstreaming for complex-trajectory transport and rotation of single particles and cells","volume":"20","author":"Ma","year":"2020","journal-title":"Lab Chip"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib44","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1038\/s41467-021-22718-8","article-title":"3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy","volume":"12","author":"L\u00e4ubli","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2025.102087_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10544-020-0470-1","article-title":"On-chip simultaneous rotation of large-scale cells by acoustically oscillating bubble array","volume":"22","author":"Tang","year":"2020","journal-title":"Biomed. Microdevices"},{"key":"10.1016\/j.mtbio.2025.102087_bib46","article-title":"Label-free spatiotemporal decoding of single-cell fate via acoustic driven 3D tomography","volume":"28","author":"Wang","year":"2024","journal-title":"Mater. Today Bio"},{"issue":"11","key":"10.1016\/j.mtbio.2025.102087_bib47","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/s41568-022-00502-0","article-title":"Big data in basic and translational cancer research","volume":"22","author":"Jiang","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mtbio.2025.102087_bib48","series-title":"Learning Image Processing with Opencv","author":"Garc\u00eda","year":"2015"},{"key":"10.1016\/j.mtbio.2025.102087_bib49","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.453","article-title":"scikit-image: image processing in python","volume":"2","author":"Van der Walt","year":"2014","journal-title":"PeerJ"},{"key":"10.1016\/j.mtbio.2025.102087_bib50","first-page":"85","volume":"1","author":"Oliphant","year":"2006","journal-title":"Guide to numpy, Trelgol Publishing USA"},{"issue":"7","key":"10.1016\/j.mtbio.2025.102087_bib51","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib52","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2144\/000112257","article-title":"CellProfiler\u2122: free, versatile software for automated biological image analysis","volume":"42","author":"Lamprecht","year":"2007","journal-title":"Biotechniques"},{"key":"10.1016\/j.mtbio.2025.102087_bib53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12859-021-04344-9","article-title":"CellProfiler 4: improvements in speed, utility and usability","volume":"22","author":"Stirling","year":"2021","journal-title":"BMC Bioinf."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib54","doi-asserted-by":"crossref","first-page":"5022","DOI":"10.1038\/s41467-023-40522-4","article-title":"iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays","volume":"14","author":"Fay","year":"2023","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.mtbio.2025.102087_bib55","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.taap.2012.04.036","article-title":"Verapamil stereoisomers induce antiproliferative effects in vascular smooth muscle cells via autophagy","volume":"262","author":"Salabei","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1\u20132","key":"10.1016\/j.mtbio.2025.102087_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vph.2011.06.001","article-title":"Nifedipine inhibits vascular smooth muscle cell proliferation and reactive oxygen species production through AMP-Activated protein kinase signaling pathway","volume":"56","author":"Sung","year":"2012","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.mtbio.2025.102087_bib57","series-title":"Learning Opencv: Computer Vision with the Opencv Library","author":"Bradski","year":"2008"},{"key":"10.1016\/j.mtbio.2025.102087_bib58","series-title":"2004 IEEE International Conference on Systems, Man and Cybernetics (IEEE Cat. No. 04CH37583)","first-page":"3099","article-title":"Background subtraction techniques: a review","author":"Piccardi","year":"2004"},{"issue":"4","key":"10.1016\/j.mtbio.2025.102087_bib59","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/wics.101","article-title":"Principal component analysis","volume":"2","author":"Abdi","year":"2010","journal-title":"Wiley interdisciplinary reviews: Comput. Stat."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib60","doi-asserted-by":"crossref","first-page":"100","DOI":"10.2307\/2346830","article-title":"A k-means clustering algorithm","volume":"28","author":"Hartigan","year":"1979","journal-title":"Applied statistics"},{"key":"10.1016\/j.mtbio.2025.102087_bib61","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.patcog.2019.01.006","article-title":"Wider or deeper: revisiting the resnet model for visual recognition","volume":"90","author":"Wu","year":"2019","journal-title":"Pattern Recogn."},{"issue":"8","key":"10.1016\/j.mtbio.2025.102087_bib62","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1162\/neco.1997.9.8.1735","article-title":"Long short-term memory","volume":"9","author":"Hochreiter","year":"1997","journal-title":"Neural Comput"},{"issue":"7954","key":"10.1016\/j.mtbio.2025.102087_bib63","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/s41586-023-05828-9","article-title":"Fast and sensitive GCaMP calcium indicators for imaging neural populations","volume":"615","author":"Zhang","year":"2023","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.mtbio.2025.102087_bib64","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.cell.2022.01.007","article-title":"Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine","volume":"185","author":"Kishi","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.mtbio.2025.102087_bib65","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.bios.2018.09.046","article-title":"3D cell-based biosensor for cell viability and drug assessment by 3D electric cell\/matrigel-substrate impedance sensing","volume":"130","author":"Pan","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102087_bib66","doi-asserted-by":"crossref","DOI":"10.1038\/srep30892","article-title":"Excitation light dose engineering to reduce photo-bleaching and photo-toxicity","volume":"6","author":"Boudreau","year":"2016","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.mtbio.2025.102087_bib67","first-page":"792","article-title":"Partial least square regression (PLS regression)","volume":"6","author":"Abdi","year":"2003","journal-title":"Encyclopedia for research methods for the social sciences"},{"key":"10.1016\/j.mtbio.2025.102087_bib68","series-title":"Nifedipine","author":"Khan","year":"2019"},{"key":"10.1016\/j.mtbio.2025.102087_bib69","doi-asserted-by":"crossref","first-page":"169","DOI":"10.2165\/00003495-197815030-00001","article-title":"Verapamil: a review of its pharmacological properties and therapeutic use","volume":"15","author":"Singh","year":"1978","journal-title":"Drugs"},{"issue":"7","key":"10.1016\/j.mtbio.2025.102087_bib70","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/nmeth.2075","article-title":"Icy: an open bioimage informatics platform for extended reproducible research","volume":"9","author":"De Chaumont","year":"2012","journal-title":"Nat. Methods"},{"issue":"12","key":"10.1016\/j.mtbio.2025.102087_bib71","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1038\/s41592-019-0582-9","article-title":"Ilastik: interactive machine learning for (bio) image analysis","volume":"16","author":"Berg","year":"2019","journal-title":"Nat. Methods"}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642500657X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642500657X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T21:20:34Z","timestamp":1772745634000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S259000642500657X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":71,"alternative-id":["S259000642500657X"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.102087","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acousto-optogenetics bandpass stabilizer: A programmable platform for mapping single-cell phenotypic life trajectories","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2025.102087","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102087"}}