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Rev."},{"issue":"10","key":"10.1016\/j.mtbio.2025.102331_bib111","doi-asserted-by":"crossref","DOI":"10.1088\/0957-4484\/24\/10\/105102","article-title":"Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo","volume":"24","author":"Yin","year":"2013","journal-title":"Nanotechnology"},{"issue":"10","key":"10.1016\/j.mtbio.2025.102331_bib112","doi-asserted-by":"crossref","first-page":"13268","DOI":"10.1021\/acsnano.0c05062","article-title":"Efficient lymph node-targeted delivery of personalized cancer vaccines with reactive oxygen species-inducing reduced graphene oxide nanosheets","volume":"14","author":"Xu","year":"2020","journal-title":"ACS Nano"},{"issue":"33","key":"10.1016\/j.mtbio.2025.102331_bib113","doi-asserted-by":"crossref","first-page":"7942","DOI":"10.1039\/D3TB01019H","article-title":"Modulation of two-dimensional palladium nanozyme activity to enhance chemodynamic\/photothermal combined therapy for melanoma","volume":"11","author":"Sun","year":"2023","journal-title":"J. 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Rev."},{"issue":"14","key":"10.1016\/j.mtbio.2025.102331_bib154","doi-asserted-by":"crossref","first-page":"6936","DOI":"10.7150\/thno.58173","article-title":"A spontaneous multifunctional hydrogel vaccine amplifies the innate immune response to launch a powerful antitumor adaptive immune response","volume":"11","author":"Liang","year":"2021","journal-title":"Theranostics"},{"key":"10.1016\/j.mtbio.2025.102331_bib155","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.biomaterials.2018.01.004","article-title":"Injectable polypeptide hydrogel for dual-delivery of antigen and TLR3 agonist to modulate dendritic cells in vivo and enhance potent cytotoxic T-lymphocyte response against melanoma","volume":"159","author":"Song","year":"2018","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.mtbio.2025.102331_bib156","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-004133","article-title":"BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma","volume":"10","author":"Kremenovic","year":"2022","journal-title":"J. Immunother. Cancer"},{"issue":"1","key":"10.1016\/j.mtbio.2025.102331_bib157","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1038\/s41467-023-40312-y","article-title":"Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity","volume":"14","author":"Chen","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2025.102331_bib158","first-page":"541","article-title":"Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy","volume":"9","author":"Zhou","year":"2022","journal-title":"Bioact. Mater."},{"issue":"2","key":"10.1016\/j.mtbio.2025.102331_bib159","article-title":"Dendritic cells instruct T cell anti-tumor immunity and immunotherapy response","volume":"3","author":"Xiao","year":"2025","journal-title":"Inn. 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Oncol."},{"issue":"11","key":"10.1016\/j.mtbio.2025.102331_bib169","doi-asserted-by":"crossref","first-page":"10637","DOI":"10.1021\/acsnano.3c01733","article-title":"In situ sprayed nanovaccine suppressing exosomal PD-L1 by Golgi apparatus disorganization for postsurgical melanoma immunotherapy","volume":"17","author":"Ye","year":"2023","journal-title":"ACS Nano"},{"issue":"28","key":"10.1016\/j.mtbio.2025.102331_bib170","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201801527","article-title":"Injectable bioresponsive gel depot for enhanced immune checkpoint blockade","volume":"30","author":"Yu","year":"2018","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102331_bib171","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1038\/s41467-022-31579-8","article-title":"An in situ hydrogel-mediated chemo-immunometabolic cancer therapy","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. 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Release"},{"issue":"2","key":"10.1016\/j.mtbio.2025.102331_bib181","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cell.2018.09.035","article-title":"A paradigm shift in cancer immunotherapy: from enhancement to normalization","volume":"175","author":"Sanmamed","year":"2018","journal-title":"Cell"},{"issue":"17","key":"10.1016\/j.mtbio.2025.102331_bib182","article-title":"A dual-bioresponsive drug-delivery depot for combination of epigenetic modulation and immune checkpoint blockade","volume":"31","author":"Ruan","year":"2019","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.mtbio.2025.102331_bib183","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/s41392-023-01341-7","article-title":"Targeting epigenetic regulators to overcome drug resistance in cancers","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct. 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Sci."},{"issue":"11","key":"10.1016\/j.mtbio.2025.102331_bib202","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202306960","article-title":"Hydrogel-based biosensors for bacterial infections","volume":"20","author":"Sun","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.mtbio.2025.102331_bib203","article-title":"NIR-responsive injectable hydrogel cross-linked by homobifunctional PEG for photo-hyperthermia of melanoma, antibacterial wound healing, and preventing post-operative adhesion","volume":"26","author":"Nosrati-Siahmazgi","year":"2024","journal-title":"Mater. Today Bio"},{"issue":"18","key":"10.1016\/j.mtbio.2025.102331_bib204","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202207342","article-title":"Copper-zinc bimetallic single-atom catalysts with localized surface plasmon resonance-enhanced photothermal effect and catalytic activity for melanoma treatment and wound-healing","volume":"10","author":"Liu","year":"2023","journal-title":"Adv. Sci."},{"key":"10.1016\/j.mtbio.2025.102331_bib205","doi-asserted-by":"crossref","DOI":"10.1016\/j.nanoen.2021.106906","article-title":"Self-powered and photothermal electronic skin patches for accelerating wound healing","volume":"93","author":"Du","year":"2022","journal-title":"Nano Energy"},{"issue":"14","key":"10.1016\/j.mtbio.2025.102331_bib206","doi-asserted-by":"crossref","first-page":"13296","DOI":"10.1021\/acsnano.3c01158","article-title":"A \"test-to-treat\" pad for real-time visual monitoring of bacterial infection and on-site performing smart therapy strategies","volume":"17","author":"Zhao","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2025.102331_bib207","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.biomaterials.2018.06.004","article-title":"Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes","volume":"178","author":"Zhao","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2025.102331_bib208","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2022.108211","article-title":"The roles of TGF-\u03b2 and VEGF pathways in the suppression of antitumor immunity in melanoma and other solid tumors","volume":"240","author":"Bu","year":"2022","journal-title":"Pharmacol. Ther."},{"issue":"30","key":"10.1016\/j.mtbio.2025.102331_bib209","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202304023","article-title":"Adipose-derived mesenchymal stem cell-derived exosomes biopotentiated extracellular matrix hydrogels accelerate diabetic wound healing and skin regeneration","volume":"10","author":"Song","year":"2023","journal-title":"Adv. Sci."},{"issue":"12","key":"10.1016\/j.mtbio.2025.102331_bib210","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202414468","article-title":"Biomineralized nanocomposite-integrated microneedle patch for combined brachytherapy and photothermal therapy in postoperative melanoma recurrence and infectious wound healing","volume":"12","author":"Liu","year":"2025","journal-title":"Adv. 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