{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:14:13Z","timestamp":1790187253130,"version":"4.1.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370984"],"award-info":[{"award-number":["82370984"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370980"],"award-info":[{"award-number":["82370980"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82571118"],"award-info":[{"award-number":["82571118"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2509100"],"award-info":[{"award-number":["2023YFC2509100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["22ZR1437600"],"award-info":[{"award-number":["22ZR1437600"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2025M781698"],"award-info":[{"award-number":["2025M781698"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23Y31900400"],"award-info":[{"award-number":["23Y31900400"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.mtbio.2026.102906","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:30:51Z","timestamp":1770683451000},"page":"102906","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Fmoc-DDT@Fos hydrogel mitigates temporomandibular joint osteoarthritis through regulating macrophage reprogramming and ferroptosis"],"prefix":"10.1016","volume":"37","author":[{"given":"Yuxin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dahe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaokun","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingtong","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0957-592X","authenticated-orcid":false,"given":"Jiajia","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1630-5389","authenticated-orcid":false,"given":"Chi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mtbio.2026.102906_bib1","doi-asserted-by":"crossref","first-page":"4921","DOI":"10.3390\/jcm14144921","article-title":"Structural features of the temporomandibular joint evaluated by MRI and their association with oral function and craniofacial morphology in female patients with malocclusion: a cross-sectional","volume":"14","author":"Kaneda","year":"2025","journal-title":"Study, JCM"},{"key":"10.1016\/j.mtbio.2026.102906_bib2","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.3390\/jcm14134639","article-title":"Temporomandibular joint ankylosis: long-term outcomes with one-stage resection and reconstruction using total joint alloplastic Replacement-A 20-Year experience","volume":"14","author":"Gerbino","year":"2025","journal-title":"JCM"},{"key":"10.1016\/j.mtbio.2026.102906_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.5125\/jkaoms.2022.48.1.50","article-title":"Ma. de los A. Soria-Bastida, A home-based exercise program for temporomandibular joint osteoarthritis: pain, functionality, and joint structure","volume":"48","author":"Mac\u00edas-Hern\u00e1ndez","year":"2022","journal-title":"JKAOMS"},{"key":"10.1016\/j.mtbio.2026.102906_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s13148-021-01008-6","article-title":"BRD4 inhibition alleviates mechanical stress-induced TMJ OA-like pathological changes and attenuates TREM1-mediated inflammatory response","volume":"13","author":"Huang","year":"2021","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.mtbio.2026.102906_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2022.1074536","article-title":"A new frontier in temporomandibular joint osteoarthritis treatment: exosome-based therapeutic strategy","volume":"10","author":"Yuan","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.mtbio.2026.102906_bib6","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s10194-015-0586-5","article-title":"Reported concepts for the treatment modalities and pain management of temporomandibular disorders","volume":"16","author":"Wieckiewicz","year":"2015","journal-title":"J. Headache Pain"},{"key":"10.1016\/j.mtbio.2026.102906_bib7","doi-asserted-by":"crossref","DOI":"10.1186\/s12875-024-02398-1","article-title":"Dental practitioners' knowledge, management practices, and attitudes toward collaboration in the treatment of temporomandibular joint disorders: a mixed-methods study","volume":"25","author":"Taqi","year":"2024","journal-title":"BMC Prim. Care."},{"key":"10.1016\/j.mtbio.2026.102906_bib8","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/cre2.327","article-title":"Electroporation technique for joint pain-Pilot feasibility study on TMD patients","volume":"6","author":"Tartaglia","year":"2020","journal-title":"Clin. Exp. Dental Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib9","first-page":"124","article-title":"Managements of sleep bruxism in adult: a systematic review, Japanese dental","volume":"58","author":"Minakuchi","year":"2022","journal-title":"Sci. Rev."},{"key":"10.1016\/j.mtbio.2026.102906_bib10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.17219\/dmp\/132896","article-title":"One year into the COVID-19 pandemic-temporomandibular disorders and bruxism: what we have learned and what we can do to improve our manner of treatment","volume":"58","author":"Alona","year":"2021","journal-title":"Dent. Med. Probl."},{"key":"10.1016\/j.mtbio.2026.102906_bib11","doi-asserted-by":"crossref","DOI":"10.1590\/1678-7757-2021-0059","article-title":"Effects of therapeutic and aerobic exercise programs in temporomandibular disorder-associated headaches","volume":"29","author":"Moleirinho-Alves","year":"2021","journal-title":"J. Appl. Oral Sci."},{"key":"10.1016\/j.mtbio.2026.102906_bib12","article-title":"Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement","volume":"15","author":"Trisolino","year":"2020","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib13","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2022-002735","article-title":"Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis","volume":"9","author":"Burmester","year":"2023","journal-title":"RMD Open"},{"key":"10.1016\/j.mtbio.2026.102906_bib14","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.3390\/pharmaceutics15071972","article-title":"Recent advancement in mRNA vaccine development and applications","volume":"15","author":"Al Fayez","year":"2023","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.mtbio.2026.102906_bib15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/mco2.101","article-title":"Nasally inhaled therapeutics and vaccination for COVID\u201019: developments and challenges","volume":"2","author":"Xi","year":"2021","journal-title":"MedComm"},{"key":"10.1016\/j.mtbio.2026.102906_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202301096","article-title":"Peptide hydrogels as immunomaterials and their use in cancer immunotherapy delivery","volume":"12","author":"Falcone","year":"2023","journal-title":"Adv Healthcare Materials"},{"key":"10.1016\/j.mtbio.2026.102906_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123283","article-title":"Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis","volume":"321","author":"Lu","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.102906_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.156541","article-title":"Extracellular vesicles from inflammatory-stimulated BMSCs ameliorate osteoarthritis via Rpl14 mediated synovial macrophage polarization","volume":"499","author":"Lu","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.mtbio.2026.102906_bib19","doi-asserted-by":"crossref","first-page":"4616","DOI":"10.3390\/molecules28124616","article-title":"The role of extracellular matrix (ECM) adhesion motifs in functionalised hydrogels","volume":"28","author":"Morwood","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.mtbio.2026.102906_bib20","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1111\/jocd.15631","article-title":"Sodium alginate\/gelatin hydrogels loaded with adipose\u2010derived mesenchymal stem cells promote wound healing in diabetic rats","volume":"22","author":"Sheng","year":"2023","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.mtbio.2026.102906_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.113996","article-title":"Fostamatinib alleviates temporomandibular joint osteoarthritis by maintaining cartilage homeostasis through MAPK\/NF-\u03baB and AKT\/mTOR pathways","volume":"147","author":"Zhang","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.mtbio.2026.102906_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202104165","article-title":"Self\u2010assembling peptide\u2010based hydrogels for wound tissue repair","volume":"9","author":"Guan","year":"2022","journal-title":"Adv. Sci."},{"key":"10.1016\/j.mtbio.2026.102906_bib23","doi-asserted-by":"crossref","first-page":"8686","DOI":"10.1039\/D1TB01628H","article-title":"De novo design of self-assembly hydrogels based on Fmoc-diphenylalanine providing drug release","volume":"9","author":"Li","year":"2021","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.mtbio.2026.102906_bib24","article-title":"Hydrogel\u2010based growth factor delivery platforms: strategies and recent advances","volume":"36","author":"Shan","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102906_bib25","article-title":"Synovial macrophages in cartilage destruction and regeneration-lessons learnt from osteoarthritis and synovial chondromatosis","volume":"17","author":"Li","year":"2021","journal-title":"Biomed. Mater."},{"key":"10.1016\/j.mtbio.2026.102906_bib26","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18172","article-title":"The relationship of ALPK1, hyaluronic acid and M1 macrophage polarization in the temporomandibular joint synovitis","volume":"28","author":"Zhao","year":"2024","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.mtbio.2026.102906_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202100176","article-title":"Rational design of immunomodulatory hydrogels for chronic wound healing","volume":"33","author":"Kharaziha","year":"2021","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102906_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202270257","article-title":"Osteoimmunity\u2010regulating biomimetically hierarchical scaffold for augmented bone regeneration","volume":"34","author":"Zhang","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102906_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121538","article-title":"Biomimetic glycopeptide hydrogel coated PCL\/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo-immunomodulation","volume":"285","author":"Wang","year":"2022","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.102906_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-02568-6","article-title":"Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis","volume":"11","author":"Novikov","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mtbio.2026.102906_bib31","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1111\/jcmm.14893","article-title":"Chondroprotective and anti\u2010inflammatory effects of amurensin H by regulating TLR4\/Syk\/NF\u2010\u03baB signals","volume":"24","author":"Ma","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.mtbio.2026.102906_bib32","article-title":"Correction to: fostamatinib: a review in chronic immune thrombocytopenia","volume":"81","author":"Paik","year":"2021","journal-title":"Drugs"},{"key":"10.1016\/j.mtbio.2026.102906_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/s41420-025-02342-x","article-title":"Syk inhibitor attenuates lupus in Fc\u03b3RIIb-\/- mice through the inhibition of DNA extracellular traps from macrophages and neutrophils via p38MAPK-dependent pathway","volume":"11","author":"Sae-khow","year":"2025","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.mtbio.2026.102906_bib34","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.actbio.2020.07.001","article-title":"Polypeptide-based self-healing hydrogels: design and biomedical applications","volume":"113","author":"Cai","year":"2020","journal-title":"Acta Biomater."},{"key":"10.1016\/j.mtbio.2026.102906_bib35","doi-asserted-by":"crossref","unstructured":"R. Binaymotlagh, L. Chronopoulou, C. Palocci, Peptide-based hydrogels: template materials for tissue engineering, JFB. 14 (2023) 233. https:\/\/doi.org\/10.3390\/jfb14040233.","DOI":"10.3390\/jfb14040233"},{"key":"10.1016\/j.mtbio.2026.102906_bib36","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jcis.2023.09.191","article-title":"Titanium dioxide nanoparticles embedded in assembled dipeptide hydrogels for microfluidic photodegradation","volume":"654","author":"Li","year":"2024","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.mtbio.2026.102906_bib37","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jcis.2022.12.166","article-title":"Fmoc-diphenylalanine gelating nanoarchitectonics: a simplistic peptide self-assembly to meet complex applications","volume":"636","author":"Wang","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.mtbio.2026.102906_bib38","article-title":"NUPR1 is a critical repressor of ferroptosis","volume":"12","author":"Liu","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2026.102906_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2023.113612","article-title":"Ebselen restores peri-implantitis-induced osteogenic inhibition via suppressing BMSCs ferroptosis","volume":"427","author":"Huang","year":"2023","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib40","article-title":"mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2026.102906_bib41","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/s41422-019-0263-3","article-title":"The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression","volume":"30","author":"Lei","year":"2020","journal-title":"Cell Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib42","doi-asserted-by":"crossref","DOI":"10.1038\/s41420-023-01653-1","article-title":"\u03b4-Tocotrienol preconditioning improves the capability of bone marrow-derived mesenchymal stem cells in promoting wound healing by inhibiting BACH1-related ferroptosis","volume":"9","author":"He","year":"2023","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.mtbio.2026.102906_bib43","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.2147\/JIR.S432111","article-title":"Targeting ferroptosis in bone-related diseases: facts and perspectives","volume":"16","author":"Chen","year":"2023","journal-title":"JIR"},{"key":"10.1016\/j.mtbio.2026.102906_bib44","doi-asserted-by":"crossref","first-page":"2058.e1","DOI":"10.1016\/j.joms.2021.05.001","article-title":"Mechanical loading disrupts focal adhesion kinase activation in mandibular fibrochondrocytes during murine temporomandibular joint osteoarthritis","volume":"79","author":"Reed","year":"2021","journal-title":"J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.mtbio.2026.102906_bib45","doi-asserted-by":"crossref","DOI":"10.20517\/mtod.2023.38","article-title":"Clinical frontiers of metabolic bone disorders: a comprehensive review","volume":"4","author":"Ansari","year":"2023","journal-title":"Metab Target Organ Damage"},{"key":"10.1016\/j.mtbio.2026.102906_bib46","doi-asserted-by":"crossref","first-page":"e721","DOI":"10.5435\/JAAOS-D-21-01233","article-title":"AAOS clinical practice guideline summary: management of osteoarthritis of the knee (Nonarthroplasty), third edition","volume":"30","author":"Brophy","year":"2022","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"10.1016\/j.mtbio.2026.102906_bib47","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1038\/s12276-022-00885-y","article-title":"The mitochondrial unfolded protein response (UPRmt) protects against osteoarthritis","volume":"54","author":"Zhou","year":"2022","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.mtbio.2026.102906_bib48","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1002\/bit.26736","article-title":"Live imaging flow bioreactor for the simulation of articular cartilage regeneration after treatment with bioactive hydrogel","volume":"115","author":"Bar","year":"2018","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.mtbio.2026.102906_bib49","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1016\/j.xphs.2021.04.001","article-title":"Intra-articular dual drug delivery for synergistic rheumatoid arthritis treatment","volume":"110","author":"Zewail","year":"2021","journal-title":"J. Pharmaceut. Sci."},{"key":"10.1016\/j.mtbio.2026.102906_bib50","doi-asserted-by":"crossref","first-page":"6758","DOI":"10.1038\/s41467-022-34481-5","article-title":"Nanozyme-reinforced hydrogel as a HO-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy","volume":"13","author":"Zhao","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mtbio.2026.102906_bib51","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3390\/pharmaceutics14030574","article-title":"Drug delivery strategies and biomedical significance of hydrogels: translational considerations","volume":"14","author":"Raina","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.mtbio.2026.102906_bib52","doi-asserted-by":"crossref","first-page":"e336","DOI":"10.1016\/j.jormas.2021.08.003","article-title":"Systematic review of studies on drug-delivery systems for management of temporomandibular-joint osteoarthritis","volume":"123","author":"Barry","year":"2022","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"key":"10.1016\/j.mtbio.2026.102906_bib53","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.1007\/s00784-021-04241-8","article-title":"Hyaluronan injection versus oral glucosamine and diclofenac in the treatment of temporomandibular joint osteoarthritis","volume":"26","author":"Cen","year":"2021","journal-title":"Clin. Oral Invest."},{"key":"10.1016\/j.mtbio.2026.102906_bib54","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1016\/j.apsb.2021.04.023","article-title":"Nanomedicine for acute respiratory distress syndrome: the latest application, targeting strategy, and rational design","volume":"11","author":"Qiao","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.mtbio.2026.102906_bib55","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/art.42037","article-title":"2021 American college of rheumatology guideline for the treatment of juvenile idiopathic arthritis: therapeutic approaches for oligoarthritis, temporomandibular joint arthritis, and systemic juvenile idiopathic arthritis","volume":"74","author":"Onel","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.mtbio.2026.102906_bib56","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/acr.24853","article-title":"2021 American college of rheumatology guideline for the treatment of juvenile idiopathic arthritis: therapeutic approaches for oligoarthritis, temporomandibular joint arthritis, and systemic juvenile idiopathic arthritis","volume":"74","author":"Onel","year":"2022","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib57","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/j.joca.2021.08.005","article-title":"Effects of mechanical stress and deficiency of dihydrotestosterone or 17\u03b2-estradiol on temporomandibular joint osteoarthritis in mice","volume":"29","author":"Ootake","year":"2021","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.mtbio.2026.102906_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123230","article-title":"Biocompatibility and therapeutic efficacy of crosslinked hydrogel filled 3D-printed nerve conduit for sacral nerve injury repair","volume":"320","author":"Lu","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.102906_bib59","article-title":"Metabolic control of autoimmunity and tissue inflammation in rheumatoid arthritis","volume":"12","author":"Qiu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mtbio.2026.102906_bib60","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1038\/s41590-023-01642-7","article-title":"Depletion of slow-cycling PDGFR\u03b1+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis","volume":"24","author":"Di Carlo","year":"2023","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.mtbio.2026.102906_bib61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-3-030-62026-4_4","article-title":"The role of NCOA4-Mediated ferritinophagy in ferroptosis","author":"Santana-Codina","year":"2021","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.mtbio.2026.102906_bib62","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/s41416-022-01998-x","article-title":"Ferroptosis in hepatocellular carcinoma: mechanisms and targeted therapy","volume":"128","author":"Ajoolabady","year":"2022","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.mtbio.2026.102906_bib63","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.yjmcc.2022.10.004","article-title":"Ferroptosis in heart failure","volume":"173","author":"Yang","year":"2022","journal-title":"J. Mol. Cellular Cardiol."},{"key":"10.1016\/j.mtbio.2026.102906_bib64","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1177\/00220345241242389","article-title":"Inflammation triggers chondrocyte ferroptosis in TMJOA via HIF-1\u03b1\/TFRC","volume":"103","author":"Chen","year":"2024","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.mtbio.2026.102906_bib65","first-page":"212","article-title":"Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis","volume":"40","author":"Guo","year":"2024","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.mtbio.2026.102906_bib66","article-title":"Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426001493?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426001493?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:27:26Z","timestamp":1777634846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006426001493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":66,"alternative-id":["S2590006426001493"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.102906","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fmoc-DDT@Fos hydrogel mitigates temporomandibular joint osteoarthritis through regulating macrophage reprogramming and ferroptosis","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.102906","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102906"}}