{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:05:12Z","timestamp":1793397912545,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Zhejiang Province Natural Science Foundation","doi-asserted-by":"publisher","award":["LKLY25H180012"],"award-info":[{"award-number":["LKLY25H180012"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018916","name":"Suzhou Municipal Health Commission","doi-asserted-by":"publisher","award":["GSWS2024140"],"award-info":[{"award-number":["GSWS2024140"]}],"id":[{"id":"10.13039\/100018916","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018916","name":"Suzhou Municipal Health Commission","doi-asserted-by":"publisher","award":["LCZX202317"],"award-info":[{"award-number":["LCZX202317"]}],"id":[{"id":"10.13039\/100018916","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008868","name":"Jiangsu Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["BE2022737"],"award-info":[{"award-number":["BE2022737"]}],"id":[{"id":"10.13039\/501100008868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018556","name":"Science and Technology Program of Suzhou","doi-asserted-by":"publisher","award":["SKY2023062"],"award-info":[{"award-number":["SKY2023062"]}],"id":[{"id":"10.13039\/501100018556","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.mtbio.2026.102933","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T07:22:57Z","timestamp":1771226577000},"page":"102933","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Charge\/stiffness-tunable nano-microsphere overcomes intestinal mucosal barrier for rheumatoid arthritis treatment"],"prefix":"10.1016","volume":"37","author":[{"given":"Yingchun","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanrong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheyuan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1809-3810","authenticated-orcid":false,"given":"Xing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mtbio.2026.102933_bib1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1136\/ard-2022-223365","article-title":"Efficacy of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis","volume":"82","author":"Kerschbaumer","year":"2023","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mtbio.2026.102933_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20240020","article-title":"Developing functional hydrogels for treatment of oral diseases","volume":"3","author":"Song","year":"2024","journal-title":"Smart Medicine"},{"key":"10.1016\/j.mtbio.2026.102933_bib3","doi-asserted-by":"crossref","DOI":"10.59717\/j.xinn-life.2023.100015","article-title":"Gasotransmitter delivery for bone diseases and regeneration","volume":"1","author":"Xu","year":"2023","journal-title":"Innov Life"},{"key":"10.1016\/j.mtbio.2026.102933_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202206821","article-title":"Oral delivery of siRNA using fluorinated, small\u2010sized nanocapsules toward anti\u2010inflammation treatment","volume":"35","author":"Wei","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib5","doi-asserted-by":"crossref","first-page":"27294","DOI":"10.1021\/acsnano.5c04655","article-title":"Biomimetic immunoregulators for the multi-target inflammation interruption in autoimmune diseases","volume":"19","author":"Liu","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2026.102933_bib6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.34133\/research.0003","article-title":"In situ-activated phospholipid-mimic artemisinin prodrug via injectable hydrogel nano\/microsphere for rheumatoid arthritis therapy","volume":"2022","author":"Du","year":"2022","journal-title":"Research"},{"key":"10.1016\/j.mtbio.2026.102933_bib7","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jconrel.2023.08.044","article-title":"Bioinspired fine-tuning of the mechanical rigidity of SNEDDS for the efficient crossing of multiple gastrointestinal barriers","volume":"362","author":"Li","year":"2023","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2026.102933_bib8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jconrel.2021.11.026","article-title":"Coordination of rigidity modulation and targeting ligand modification on orally-delivered nanoparticles for the treatment of liver fibrosis","volume":"341","author":"Yu","year":"2022","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2026.102933_bib9","doi-asserted-by":"crossref","first-page":"13044","DOI":"10.1021\/acsnano.3c02403","article-title":"Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective","volume":"17","author":"Ejazi","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2026.102933_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/science.abb1590","article-title":"An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function","volume":"372","author":"Nystr\u00f6m","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.mtbio.2026.102933_bib11","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/s12276-023-00960-y","article-title":"Intestinal mucus components and secretion mechanisms: what we do and do not know","volume":"55","author":"Song","year":"2023","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.mtbio.2026.102933_bib12","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1021\/acssynbio.3c00061","article-title":"Engineering tissue-scale properties with synthetic cells: forging one from many","volume":"12","author":"Lin","year":"2023","journal-title":"ACS Synth. Biol."},{"key":"10.1016\/j.mtbio.2026.102933_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.conbuildmat.2024.136670","article-title":"Solid-liquid particle flow sealing mucus (PFSM) in enhancing coalbed methane (CBM) recovery: multiple-perspectives analysis and mechanism insights","volume":"435","author":"Cheng","year":"2024","journal-title":"Constr. Build. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib14","article-title":"Bioinspired carbon quantum dots nanofluid fabricated by a facile two-step synthesis toward high performance lubrication","author":"Yu","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.mtbio.2026.102933_bib15","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bmt.2024.07.001","article-title":"Nano-enhanced nature medicine for ischemic stroke: opportunities and challenges","volume":"7","author":"Yang","year":"2024","journal-title":"Biomed Technol"},{"key":"10.1016\/j.mtbio.2026.102933_bib16","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.1039\/D0CS01127D","article-title":"Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine","volume":"50","author":"de Almeida","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.mtbio.2026.102933_bib17","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.jconrel.2022.03.046","article-title":"The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs","volume":"345","author":"LoPresti","year":"2022","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.mtbio.2026.102933_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20240053","article-title":"Drug\u2010phospholipid conjugate nano\u2010assembly for drug delivery","volume":"3","author":"Zhao","year":"2024","journal-title":"Smart Medicine"},{"key":"10.1016\/j.mtbio.2026.102933_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202201942","article-title":"Low melting point alloys enabled stiffness tunable advanced materials","volume":"32","author":"Hao","year":"2022","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib20","first-page":"92","article-title":"Microenvironment-responsive nanosystems for osteoarthritis therapy","volume":"5","author":"Li","year":"2024","journal-title":"Eng. Regen."},{"key":"10.1016\/j.mtbio.2026.102933_bib21","doi-asserted-by":"crossref","first-page":"30017","DOI":"10.1021\/acsnano.4c10886","article-title":"Inflammation-responsive polyion complex vesicles for autoimmune disease therapy via cell-free DNA scavenging and inflammatory microenvironment modulation","volume":"18","author":"Zhou","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2026.102933_bib22","article-title":"Membrane fusion strategy boosts immune homeostasis, mobilizing macrophages to eliminate bacteria and accelerate skin regeneration in infected burn wound","volume":"35","author":"Wang","year":"2025","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib23","article-title":"In situ proefferocytosis microspheres as macrophage polarity converters accelerate osteoarthritis treatment","author":"Wang","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.mtbio.2026.102933_bib24","article-title":"Boosting mRNA\u2010engineered monocytes via prodrug\u2010like microspheres for bone microenvironment multi\u2010phase remodeling","author":"Wu","year":"2025","journal-title":"Adv. Healthcare Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib25","article-title":"Oral administration of multistage albumin nanomedicine depots (MANDs) for targeted efficient alleviation of chronic inflammatory diseases","volume":"33","author":"Zhang","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib26","doi-asserted-by":"crossref","DOI":"10.1128\/aac.02065-21","article-title":"Dimeric artesunate glycerophosphocholine conjugate nano-assemblies as slow-release antimalarials to overcome Kelch 13 mutant artemisinin resistance","volume":"66","author":"Du","year":"2022","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.mtbio.2026.102933_bib27","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.biomaterials.2018.02.026","article-title":"Liposomes of dimeric artesunate phospholipid: a combination of dimerization and self-assembly to combat malaria","volume":"163","author":"Ismail","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.102933_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.119178","article-title":"Dimeric artesunate phospholipid-conjugated liposomes as promising anti-inflammatory therapy for rheumatoid arthritis","volume":"579","author":"Zhang","year":"2020","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.mtbio.2026.102933_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijpharm.2017.04.024","article-title":"Self-assembled liposomes of dual paclitaxel-phospholipid prodrug for anticancer therapy","volume":"526","author":"Ling","year":"2017","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.mtbio.2026.102933_bib30","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1023\/B:PHAM.0000019298.29561.cd","article-title":"Differential adhesion of normal and inflamed rat colonic mucosa by charged liposomes","volume":"21","author":"Jubeh","year":"2004","journal-title":"Pharm. Res."},{"key":"10.1016\/j.mtbio.2026.102933_bib31","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202302801","article-title":"Cellular membrane\u2010engineered nanovesicles as a three\u2010stage booster to target the lesion core","volume":"35","author":"Huang","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib32","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s12185-021-03132-8","article-title":"Risk factors for high-dose methotrexate-induced nephrotoxicity","volume":"114","author":"Kawaguchi","year":"2021","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.mtbio.2026.102933_bib33","doi-asserted-by":"crossref","DOI":"10.1088\/2752-5724\/ada62b","article-title":"Tuning gut microbiota by advanced nanotechnology","volume":"4","author":"Qi","year":"2025","journal-title":"Mater Future"},{"key":"10.1016\/j.mtbio.2026.102933_bib34","doi-asserted-by":"crossref","first-page":"5244","DOI":"10.3390\/ma16155244","article-title":"Comparative synthesis of silver nanoparticles: evaluation of chemical reduction procedures, AFM and DLS size analysis","volume":"16","author":"Chicea","year":"2023","journal-title":"Materials"},{"key":"10.1016\/j.mtbio.2026.102933_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2023.102048","article-title":"Ultra-strong penetrating and GSH-responsive oral drug delivery system improved therapeutic effect of gemcitabine for pancreatic tumors","volume":"54","author":"Zhang","year":"2024","journal-title":"Nano Today"},{"key":"10.1016\/j.mtbio.2026.102933_bib36","article-title":"Intestine\u2010targeted explosive hydrogel microsphere promotes uric acid excretion for gout therapy","volume":"36","author":"Tang","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib37","doi-asserted-by":"crossref","first-page":"37339","DOI":"10.1021\/acsnano.5c12912","article-title":"Tuning nanoparticle rigidity: from megadalton dendritic dots to mechanobiology-driven nano-bio interactions","volume":"19","author":"Zhu","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2026.102933_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.05.005","article-title":"An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers","volume":"175","author":"Xu","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.mtbio.2026.102933_bib39","article-title":"Self\u2010thermophoretic nanoparticles enhance intestinal mucus penetration and reduce pathogenic bacteria interception in colorectal cancer","volume":"33","author":"Wang","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib40","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ijpharm.2010.04.045","article-title":"The transit of dosage forms through the small intestine","volume":"395","author":"Yuen","year":"2010","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.mtbio.2026.102933_bib41","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3899\/jrheum.080505","article-title":"Telomerase transduced osteoarthritis fibroblast-like synoviocytes display a distinct gene expression profile","volume":"36","author":"Sun","year":"2009","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mtbio.2026.102933_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2023.102047","article-title":"Dual-switched carbon monoxide nano gas tank for auto-diagnosis and precision therapy of osteoarthritis","volume":"53","author":"Gao","year":"2023","journal-title":"Nano Today"},{"key":"10.1016\/j.mtbio.2026.102933_bib43","article-title":"Peptide\u2010oligonucleotide nanohybrids designed for precise gene therapy of rheumatoid arthritis","volume":"37","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib44","doi-asserted-by":"crossref","first-page":"100","DOI":"10.34133\/bmef.0100","article-title":"Machine learning approach to investigating macrophage polarization on various titanium surface characteristics","volume":"6","author":"Chen","year":"2025","journal-title":"BME Front."},{"key":"10.1016\/j.mtbio.2026.102933_bib45","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202470251","article-title":"Regulating astrocytes via short fibers for spinal cord repair","volume":"11","author":"Li","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.mtbio.2026.102933_bib46","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.cclet.2020.09.038","article-title":"The intragastrointestinal fate of paclitaxel-loaded micelles: implications on oral drug delivery","volume":"32","author":"Zoya","year":"2021","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.mtbio.2026.102933_bib47","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.actbio.2022.12.007","article-title":"Inflammation specific environment activated methotrexate-loaded nanomedicine to treat rheumatoid arthritis by immune environment reconstruction","volume":"157","author":"Tian","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.mtbio.2026.102933_bib48","doi-asserted-by":"crossref","first-page":"16","DOI":"10.34133\/bmef.0016","article-title":"Principles of nanoparticle delivery to solid tumors","volume":"4","author":"Chan","year":"2023","journal-title":"BME Front."},{"key":"10.1016\/j.mtbio.2026.102933_bib49","doi-asserted-by":"crossref","DOI":"10.1002\/EXP.20210185","article-title":"Targeting the tumor microbiota in cancer therapy basing on nanomaterials","author":"Niu","year":"2025","journal-title":"Explorations"},{"key":"10.1016\/j.mtbio.2026.102933_bib50","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.bmt.2023.09.001","article-title":"Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment","volume":"5","author":"Elumalai","year":"2024","journal-title":"Biomed Technol"},{"key":"10.1016\/j.mtbio.2026.102933_bib51","article-title":"Injectable amphipathic artesunate prodrug\u2010hydrogel microsphere as gene\/drug nano\u2010microplex for rheumatoid arthritis therapy","volume":"32","author":"Li","year":"2022","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.102933_bib52","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1016\/j.scib.2024.02.042","article-title":"A citrullinated antigenic vaccine in treatment of autoimmune arthritis","volume":"69","author":"Jin","year":"2024","journal-title":"Sci. Bull. (Taipei)"},{"key":"10.1016\/j.mtbio.2026.102933_bib53","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1021\/acs.molpharmaceut.9b00988","article-title":"Improved antitumor activity of novel redox-responsive paclitaxel-encapsulated liposomes based on disulfide phosphatidylcholine","volume":"17","author":"Du","year":"2019","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.mtbio.2026.102933_bib54","doi-asserted-by":"crossref","first-page":"21929","DOI":"10.1021\/acsomega.5c01983","article-title":"Ex vivo interaction between human gut microbiota and artemisinin: a multi-omics perspective","volume":"10","author":"Gomes","year":"2025","journal-title":"ACS Omega"},{"key":"10.1016\/j.mtbio.2026.102933_bib55","article-title":"Dual biosignal\u2010functional injectable microspheres for remodeling osteogenic microenvironment","volume":"18","author":"Sun","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.mtbio.2026.102933_bib56","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1002\/art.38030","article-title":"High\u2010resolution magnetic resonance imaging of ankle joints in murine arthritis discriminates inflammation and bone destruction in a quantifiable manner","volume":"65","author":"Rose","year":"2013","journal-title":"Arthritis Rheum."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426001766?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426001766?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:28:36Z","timestamp":1777634916000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006426001766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":56,"alternative-id":["S2590006426001766"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.102933","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Charge\/stiffness-tunable nano-microsphere overcomes intestinal mucosal barrier for rheumatoid arthritis treatment","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.102933","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102933"}}