{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:28:45Z","timestamp":1787027325412,"version":"build-2736575974"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.mtbio.2026.103387","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T16:02:21Z","timestamp":1782144141000},"page":"103387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["AIE-pharmacology: Acacetin and NMN co-delivery rescues sperm motility"],"prefix":"10.1016","volume":"39","author":[{"given":"Yujun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengfei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3883-9613","authenticated-orcid":false,"given":"Rendy","family":"Hosea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0293-964X","authenticated-orcid":false,"given":"Ben Zhong","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghua","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.mtbio.2026.103387_bib1","doi-asserted-by":"crossref","first-page":"5683","DOI":"10.1038\/s41467-020-19414-4","article-title":"Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells","volume":"11","author":"Zhao","year":"2020","journal-title":"Nature communications"},{"issue":"8","key":"10.1016\/j.mtbio.2026.103387_bib2","doi-asserted-by":"crossref","DOI":"10.1111\/and.14144","article-title":"Secretions released from mesenchymal stem cells improve spermatogenesis restoration of cytotoxic treatment with busulfan in azoospermia mice","volume":"53","author":"Cai","year":"2021","journal-title":"Andrologia"},{"issue":"6","key":"10.1016\/j.mtbio.2026.103387_bib3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/s41585-018-0003-3","article-title":"Genetics of male infertility","volume":"15","author":"Krausz","year":"2018","journal-title":"Nature reviews. Urology"},{"issue":"6","key":"10.1016\/j.mtbio.2026.103387_bib4","doi-asserted-by":"crossref","first-page":"2622","DOI":"10.7150\/thno.92416","article-title":"NAD(+) precursors promote the restoration of spermatogenesis in busulfan-treated mice through inhibiting Sirt2-regulated ferroptosis","volume":"14","author":"Feng","year":"2024","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103387_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41569-022-00735-4","article-title":"The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease","volume":"20","author":"Fang","year":"2023","journal-title":"Nature reviews. Cardiology"},{"issue":"5","key":"10.1016\/j.mtbio.2026.103387_bib6","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41571-020-00462-0","article-title":"Broadening horizons: the role of ferroptosis in cancer","volume":"18","author":"Chen","year":"2021","journal-title":"Nature reviews. Clinical oncology"},{"issue":"Pt 1","key":"10.1016\/j.mtbio.2026.103387_bib7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.freeradbiomed.2022.10.314","article-title":"Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice","volume":"193","author":"Han","year":"2022","journal-title":"Free radical biology & medicine"},{"key":"10.1016\/j.mtbio.2026.103387_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.117748","article-title":"Impact of leachate from boiled-water-treated plastic products on male reproductive health: insights from transcriptomic and metabolomic profiling","volume":"290","author":"Yu","year":"2025","journal-title":"Ecotoxicol Environ Saf"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib9","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nature reviews. Molecular cell biology"},{"issue":"14","key":"10.1016\/j.mtbio.2026.103387_bib10","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications","volume":"185","author":"Stockwell","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.mtbio.2026.103387_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102584","article-title":"Ferroptosis is critical for phthalates driving the blood-testis barrier dysfunction via targeting transferrin receptor","volume":"59","author":"Zhao","year":"2023","journal-title":"Redox biology"},{"issue":"3","key":"10.1016\/j.mtbio.2026.103387_bib12","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1021\/acsnano.1c10029","article-title":"Ferritin-nanocaged ATP traverses the blood-testis barrier and enhances sperm motility in an asthenozoospermia model","volume":"16","author":"Pang","year":"2022","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.mtbio.2026.103387_bib13","doi-asserted-by":"crossref","DOI":"10.1111\/and.13463","article-title":"Asthenozoospermia: cellular and molecular contributing factors and treatment strategies","volume":"52","author":"Shahrokhi","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.mtbio.2026.103387_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.117878","article-title":"Analysis of toxicity and mechanisms of busulfan in non-obstructive azoospermia: a genomic and toxicological approach integrating molecular docking, single-cell sequencing, and experimentation in vivo","volume":"291","author":"Hong","year":"2025","journal-title":"Ecotoxicology and environmental safety"},{"key":"10.1016\/j.mtbio.2026.103387_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123777","article-title":"Blood-testis barrier-crossing extracellular vesicles for asthenozoospermia therapy via synergistic ATP replenishment and ferroptosis suppression","volume":"327","author":"Yu","year":"2026","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib16","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/andr.12502","article-title":"European Academy of Andrology guideline Management of oligo-astheno-teratozoospermia","volume":"6","author":"Colpi","year":"2018","journal-title":"Andrology"},{"issue":"18","key":"10.1016\/j.mtbio.2026.103387_bib17","doi-asserted-by":"crossref","first-page":"4925","DOI":"10.7150\/thno.27787","article-title":"Theranostics based on AIEgens","volume":"8","author":"Wang","year":"2018","journal-title":"Theranostics"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib18","article-title":"Theranostic applications of biomolecule-responsive aggregation-induced emission luminogens","volume":"1","author":"Liao","year":"2023","journal-title":"Interdisciplinary Medicine"},{"issue":"38","key":"10.1016\/j.mtbio.2026.103387_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202303186","article-title":"Tailoring the amphiphilic structure of zwitterionic AIE photosensitizers to boost antitumor immunity","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv Mater"},{"issue":"5","key":"10.1016\/j.mtbio.2026.103387_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/agt2.366","article-title":"Self-reporting fluorescence deciphers the antibacterial nature of cationic amphiphiles: monomer or aggregate?","volume":"4","author":"Zhou","year":"2023","journal-title":"Aggregate"},{"issue":"2","key":"10.1016\/j.mtbio.2026.103387_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/agt2.164","article-title":"Molecular core\u2013shell structure design: facilitating delayed fluorescence in aggregates toward highly efficient solution-processed OLEDs","volume":"3","author":"Liu","year":"2022","journal-title":"Aggregate"},{"issue":"33","key":"10.1016\/j.mtbio.2026.103387_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202102322","article-title":"A biomimetic aggregation-induced emission photosensitizer with antigen-presenting and hitchhiking function for lipid droplet targeted photodynamic immunotherapy","volume":"33","author":"Xu","year":"2021","journal-title":"Adv Mater"},{"issue":"45","key":"10.1016\/j.mtbio.2026.103387_bib23","article-title":"Biomimetic aggregation\u2010induced emission nanodots with hitchhiking function for T cell\u2010mediated cancer targeting and NIR\u2010II fluorescence\u2010guided mild\u2010temperature photothermal therapy","volume":"32","author":"Yang","year":"2022","journal-title":"Advanced Functional Materials"},{"key":"10.1016\/j.mtbio.2026.103387_bib24","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jcis.2024.07.152","article-title":"Berberine-doped montmorillonite nanosheet for photoenhanced antibacterial therapy and wound healing","volume":"676","author":"Wang","year":"2024","journal-title":"J Colloid Interface Sci"},{"issue":"12","key":"10.1016\/j.mtbio.2026.103387_bib25","article-title":"AIEgens\/Mitochondria nanohybrids as bioactive microwave sensitizers for non-thermal microwave cancer therapy","volume":"12","author":"Yu","year":"2023","journal-title":"Adv Healthc Mater"},{"issue":"2","key":"10.1016\/j.mtbio.2026.103387_bib26","article-title":"AIEgens for microorganism-related visualization and therapy","volume":"1","author":"Ye","year":"2023","journal-title":"Interdisciplinary Medicine"},{"issue":"14","key":"10.1016\/j.mtbio.2026.103387_bib27","doi-asserted-by":"crossref","first-page":"7476","DOI":"10.1002\/anie.202005899","article-title":"NIR-II AIEgens: a win-win integration towards bioapplications","volume":"60","author":"Xu","year":"2021","journal-title":"Angewandte Chemie (International ed. in English)"},{"issue":"51","key":"10.1016\/j.mtbio.2026.103387_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202414259","article-title":"NIR-II AIEgens for infectious diseases phototheranostics","volume":"63","author":"Yan","year":"2024","journal-title":"Angewandte Chemie (International ed. in English)"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/agt2.743","article-title":"An NIR-II absorbing injectable hydrogel for boosted photo-immunotherapy toward human papillomavirus associated cancer","volume":"6","author":"Yu","year":"2025","journal-title":"Aggregate"},{"key":"10.1016\/j.mtbio.2026.103387_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.mtbio.2024.100995","article-title":"Ferritin-nanocaged aggregation-induced emission nanoaggregates for NIR-II fluorescence-guided noninvasive, controllable male contraception","volume":"25","author":"Yu","year":"2024","journal-title":"Materials today. Bio"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib31","article-title":"Exploring and leveraging aggregation effects on reactive oxygen species generation in photodynamic therapy","volume":"5","author":"Zhuang","year":"2024","journal-title":"Aggregate"},{"key":"10.1016\/j.mtbio.2026.103387_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2022.101477","article-title":"Bonsai-inspired AIE nanohybrid photosensitizer based on vermiculite nanosheets for ferroptosis-assisted oxygen self-sufficient photodynamic cancer therapy","volume":"44","author":"Yu","year":"2022","journal-title":"Nano Today"},{"key":"10.1016\/j.mtbio.2026.103387_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120598","article-title":"AIEgens for microbial detection and antimicrobial therapy","volume":"268","author":"Bai","year":"2021","journal-title":"Biomaterials"},{"issue":"31","key":"10.1016\/j.mtbio.2026.103387_bib34","doi-asserted-by":"crossref","first-page":"5429","DOI":"10.1002\/adma.201401356","article-title":"Aggregation-induced emission: the whole is more brilliant than the parts","volume":"26","author":"Mei","year":"2014","journal-title":"Advanced materials (Deerfield Beach, Fla.)"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib35","doi-asserted-by":"crossref","DOI":"10.1002\/agt2.331","article-title":"Aggregation-induced emission polymer systems with circularly polarized luminescence","volume":"4","author":"Yan","year":"2023","journal-title":"Aggregate"},{"issue":"11","key":"10.1016\/j.mtbio.2026.103387_bib36","doi-asserted-by":"crossref","first-page":"5361","DOI":"10.1039\/c1cs15113d","article-title":"Aggregation-induced emission","volume":"40","author":"Hong","year":"2011","journal-title":"Chemical Society reviews"},{"issue":"31","key":"10.1016\/j.mtbio.2026.103387_bib37","doi-asserted-by":"crossref","first-page":"6497","DOI":"10.1039\/C8SC01635F","article-title":"Exploration of biocompatible AIEgens from natural resources","volume":"9","author":"Gu","year":"2018","journal-title":"Chemical science"},{"issue":"16","key":"10.1016\/j.mtbio.2026.103387_bib38","article-title":"Ferritin-nanocaged aggregation-induced emission drug Vitexin inhibits ferroptosis to treat asthenozoospermia","volume":"36","author":"Yu","year":"2026","journal-title":"Adv. Funct. Mater"},{"issue":"6","key":"10.1016\/j.mtbio.2026.103387_bib39","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1142\/S0192415X24500654","article-title":"Acacetin is a promising drug candidate for cardiovascular diseases","volume":"52","author":"Wang","year":"2024","journal-title":"The American journal of Chinese medicine"},{"issue":"19","key":"10.1016\/j.mtbio.2026.103387_bib40","doi-asserted-by":"crossref","first-page":"9433","DOI":"10.3390\/ijms26199433","article-title":"Molecular mechanism discovery of acacetin against cancers: insights from network pharmacology and molecular docking","volume":"26","author":"Jang","year":"2025","journal-title":"International journal of molecular sciences"},{"key":"10.1016\/j.mtbio.2026.103387_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111708","article-title":"Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders","volume":"145","author":"Singh","year":"2020","journal-title":"Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association"},{"key":"10.1016\/j.mtbio.2026.103387_bib42","first-page":"2953","article-title":"Robust aptamer-polydopamine-functionalized M-PLGA-TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy","volume":"11","author":"Xu","year":"2016","journal-title":"Int J Nanomedicine"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib43","doi-asserted-by":"crossref","first-page":"470","DOI":"10.7150\/thno.14184","article-title":"Polydopamine-based surface modification of novel nanoparticle-aptamer bioconjugates for in vivo breast cancer targeting and enhanced therapeutic effects","volume":"6","author":"Tao","year":"2016","journal-title":"Theranostics"},{"issue":"31","key":"10.1016\/j.mtbio.2026.103387_bib44","doi-asserted-by":"crossref","first-page":"5770","DOI":"10.1039\/D5CC00796H","article-title":"One-pot synthesis of a highly active single-atom Pd catalyst for the Heck reaction","volume":"61","author":"Teng","year":"2025","journal-title":"Chemical Communications"},{"key":"10.1016\/j.mtbio.2026.103387_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.125093","article-title":"Intracellular mechanistic insights into cRGD-modified Bi(2)Se(3) nanofoams for enhanced photothermal therapy via exocytosis inhibition","volume":"669","author":"Ding","year":"2025","journal-title":"Int J Pharm"},{"issue":"45","key":"10.1016\/j.mtbio.2026.103387_bib46","doi-asserted-by":"crossref","first-page":"17859","DOI":"10.1039\/C7NR05997C","article-title":"Fluorine-free preparation of titanium carbide MXene quantum dots with high near-infrared photothermal performances for cancer therapy","volume":"9","author":"Yu","year":"2017","journal-title":"Nanoscale"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103387_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201603276","article-title":"Black phosphorus nanosheets as a robust delivery platform for cancer theranostics","volume":"29","author":"Tao","year":"2017","journal-title":"Advanced materials (Deerfield Beach, Fla.)"},{"issue":"7","key":"10.1016\/j.mtbio.2026.103387_bib48","doi-asserted-by":"crossref","first-page":"8521","DOI":"10.1016\/j.ceramint.2013.03.034","article-title":"Biotemplated multichannel mesoporous bioactive glass microtubes as a drug carrier","volume":"39","author":"Liu","year":"2013","journal-title":"Ceramics International"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib49","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nrm.2017.125","article-title":"Shedding light on the cell biology of extracellular vesicles","volume":"19","author":"van Niel","year":"2018","journal-title":"Nature reviews. Molecular cell biology"},{"issue":"10","key":"10.1016\/j.mtbio.2026.103387_bib50","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s41580-020-0251-y","article-title":"RNA delivery by extracellular vesicles in mammalian cells and its applications","volume":"21","author":"O'Brien","year":"2020","journal-title":"Nature reviews. Molecular cell biology"},{"issue":"4","key":"10.1016\/j.mtbio.2026.103387_bib51","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1007\/s12015-022-10499-6","article-title":"Extracellular vesicles from NMN preconditioned mesenchymal stem cells ameliorated myocardial infarction via miR-210-3p promoted angiogenesis","volume":"19","author":"Pu","year":"2023","journal-title":"Stem cell reviews and reports"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103387_bib52","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1186\/s13287-025-04460-w","article-title":"Small extracellular vesicles derived from mesenchymal stromal cells loaded with \u03b2-nicotinamide mononucleotide activate NAD(+)\/SIRT3 signaling pathway-mediated mitochondrial autophagy to delay skin aging","volume":"16","author":"Sun","year":"2025","journal-title":"Stem cell research & therapy"},{"key":"10.1016\/j.mtbio.2026.103387_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156171","article-title":"Acacetin alleviates rheumatoid arthritis by targeting HSP90 ATPase domain to promote COX-2 degradation","volume":"135","author":"Wang","year":"2024","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.mtbio.2026.103387_bib54","article-title":"Acacetin as a natural cardiovascular therapeutic: mechanisms and preclinical evidence","volume":"16","author":"Zhou","year":"2025","journal-title":"Frontiers in pharmacology"},{"key":"10.1016\/j.mtbio.2026.103387_bib55","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.theriogenology.2022.06.006","article-title":"Ameliorate effects of resveratrol and l-carnitine on the testicular tissue and sex hormones level in busulfan induced azoospermia rats","volume":"191","author":"Hafezi","year":"2022","journal-title":"Theriogenology"},{"issue":"11","key":"10.1016\/j.mtbio.2026.103387_bib56","doi-asserted-by":"crossref","DOI":"10.1111\/and.13438","article-title":"Hyperthermia versus busulfan: finding the effective method in animal model of azoospermia induction","volume":"51","author":"Ziaeipour","year":"2019","journal-title":"Andrologia"}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426006320?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426006320?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:56:27Z","timestamp":1787025387000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006426006320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":56,"alternative-id":["S2590006426006320"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103387","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"AIE-pharmacology: Acacetin and NMN co-delivery rescues sperm motility","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103387"}}