{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:02:44Z","timestamp":1790337764683,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.mtbio.2026.103481","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:33:13Z","timestamp":1785195193000},"page":"103481","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["GSH-responsive self-assembled nanoplatform synergistically enhances cuproptosis through metabolic reprogramming and oxidative stress amplification"],"prefix":"10.1016","volume":"40","author":[{"given":"Bo","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenda","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangquan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhibo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6122-3302","authenticated-orcid":false,"given":"Fangwei","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyun","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suxiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuitu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1147-1911","authenticated-orcid":false,"given":"Fanghong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.mtbio.2026.103481_bib1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41422-022-00653-7","article-title":"Cuproptosis: a copper-triggered modality of mitochondrial cell death","volume":"32","author":"Tang","year":"2022","journal-title":"Cell Res."},{"key":"10.1016\/j.mtbio.2026.103481_bib2","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.molcel.2022.05.001","article-title":"Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death","volume":"82","author":"Cobine","year":"2022","journal-title":"Mol. Cell"},{"issue":"2","key":"10.1016\/j.mtbio.2026.103481_bib3","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41568-021-00417-2","article-title":"Connecting copper and cancer: from transition metal signalling to metalloplasia","volume":"22","author":"Ge","year":"2022","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib4","article-title":"Cuproptosis: unveiling a new frontier in cancer biology and therapeutics","volume":"22","author":"Feng","year":"2024","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.mtbio.2026.103481_bib5","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2216722120","article-title":"FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery","volume":"120","author":"Zulkifli","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib6","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s13046-022-02485-0","article-title":"Elesclomol: a copper ionophore targeting mitochondrial metabolism for cancer therapy","volume":"41","author":"Zheng","year":"2022","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"10","key":"10.1016\/j.mtbio.2026.103481_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.freeradbiomed.2012.03.017","article-title":"The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells","volume":"52","author":"Nagai","year":"2012","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mtbio.2026.103481_bib8","article-title":"Orchestrating mitochondrial catastrophe: Mechanistic insights and therapeutic frontiers of cuproptosis in precision pharmacology","volume":"69","author":"El-Nablaway","year":"2026","journal-title":"Curr. Opin. Pharmacol."},{"issue":"27","key":"10.1016\/j.mtbio.2026.103481_bib9","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M111.226951","article-title":"R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization","volume":"286","author":"Shang","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.mtbio.2026.103481_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.105046","article-title":"FDX1 regulates cellular protein lipoylation through direct binding to LIAS","volume":"299","author":"Dreishpoon","year":"2023","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.mtbio.2026.103481_bib11","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/s41571-024-00876-0","article-title":"Targeting cuproplasia and cuproptosis in cancer","volume":"21","author":"Tang","year":"2024","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"7","key":"10.1016\/j.mtbio.2026.103481_bib12","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1083\/jcb.201804161","article-title":"Glutathione metabolism in cancer progression and treatment resistance","volume":"217","author":"Bansal","year":"2018","journal-title":"J. Cell. Biol."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib13","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-023-01732-y","article-title":"Cuproptosis: mechanisms and links with cancers","volume":"22","author":"Xie","year":"2023","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.mtbio.2026.103481_bib14","article-title":"Mitochondrial electron transport is the cellular target of the oncology drug elesclomol","volume":"9","author":"Blackman","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.mtbio.2026.103481_bib15","article-title":"Elesclomol loaded copper oxide nanoplatform triggers cuproptosis to enhance antitumor immunotherapy","volume":"32","author":"Lu","year":"2022","journal-title":"Cell Res"},{"key":"10.1016\/j.mtbio.2026.103481_bib16","doi-asserted-by":"crossref","DOI":"10.1017\/erm.2014.11","article-title":"Copper as a key regulator of cell signalling pathways","volume":"16","author":"Grubman","year":"2014","journal-title":"Expert Rev. Mol. Med."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib17","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cmet.2015.12.006","article-title":"The emerging hallmarks of cancer metabolism","volume":"23","author":"Pavlova","year":"2016","journal-title":"Cell Metab."},{"issue":"6090","key":"10.1016\/j.mtbio.2026.103481_bib18","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1126\/science.1218099","article-title":"A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans","volume":"337","author":"Bricker","year":"2022","journal-title":"Science"},{"issue":"6090","key":"10.1016\/j.mtbio.2026.103481_bib19","doi-asserted-by":"crossref","DOI":"10.1126\/science.1218530","article-title":"Identification and functional expression of the mitochondrial pyruvate carrier","volume":"337","author":"Herzig","year":"2012","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mtbio.2026.103481_bib20","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.molcel.2014.09.026","article-title":"A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth","volume":"56","author":"Schell","year":"2024","journal-title":"Mol. Cell"},{"issue":"8061","key":"10.1016\/j.mtbio.2026.103481_bib21","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/s41586-025-08667-y","article-title":"Structure of mitochondrial pyruvate carrier and its inhibition mechanism","volume":"641","author":"He","year":"2025","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib22","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1134\/S001249662460060X","article-title":"Thioridazine induces increase in expression of the pyruvate transporter MPC1 associated with immune infiltration in malignant tumors","volume":"520","author":"Bogomolova","year":"2025","journal-title":"Dokl. Biol. Sci."},{"issue":"2","key":"10.1016\/j.mtbio.2026.103481_bib23","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.cmet.2019.11.002","article-title":"Regulation of tumor initiation by the mitochondrial pyruvate carrier","volume":"31","author":"Bensard","year":"2020","journal-title":"Cell Metab."},{"key":"10.1016\/j.mtbio.2026.103481_bib24","doi-asserted-by":"crossref","first-page":"6329","DOI":"10.2147\/JIR.S473932","article-title":"Alterations in astrocyte subpopulations in glioma and identification of cuproptosis-related genes using single-cell RNA sequencina","volume":"17","author":"Huang","year":"2024","journal-title":"J. Inflamm. Res."},{"issue":"50","key":"10.1016\/j.mtbio.2026.103481_bib25","doi-asserted-by":"crossref","first-page":"34244","DOI":"10.1021\/acsnano.4c12123","article-title":"A peptide-copper self-assembled nanoparticle for enhanced cuproptosis by metabolic reprogramming in tumor cells","volume":"18","author":"Zhang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.mtbio.2026.103481_bib26","doi-asserted-by":"crossref","first-page":"6329","DOI":"10.2147\/JIR.S473932","article-title":"Alterations in astrocyte subpopulations in glioma and identification of cuproptosis-related genes using single-cell RNA sequencing","volume":"17","author":"Huang","year":"2024","journal-title":"J. Inflamm. Res."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib27","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-025-03722-2","article-title":"Cascade-targeting copper homeostasis nano-regulators for mild-photothermal boosted cuproptosis\/ferroptosis mediated breast cancer therapy","volume":"23","author":"Liang","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.mtbio.2026.103481_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.123201","article-title":"Hyaluronan-decorated CuO(2)-doxorubicin nanodot clusters for targetedly sensitizing cuproptosis in breast cancer via a three-pronged strategy","volume":"352","author":"Qian","year":"2025","journal-title":"Carbohydr .Polym."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib29","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/s41392-022-01229-y","article-title":"Copper homeostasis and cuproptosis in health and diseas","volume":"7","author":"Chen","year":"2022","journal-title":"Signal Transduct. Target Ther."},{"issue":"5","key":"10.1016\/j.mtbio.2026.103481_bib30","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.molmed.2013.12.001","article-title":"Nanomedicine-based strategies for treatment of atherosclerosis","volume":"20","author":"Schiener","year":"2014","journal-title":"Trends Mol. Med."},{"issue":"16","key":"10.1016\/j.mtbio.2026.103481_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/cancers17162628","article-title":"Nanoparticle-based delivery strategies for combating drug resistance in cancer therapeutics","volume":"17","author":"Park","year":"2025","journal-title":"Cancers (Basel)"},{"issue":"16","key":"10.1016\/j.mtbio.2026.103481_bib32","doi-asserted-by":"crossref","first-page":"5705","DOI":"10.1039\/D5BM00954E","article-title":"Composite nano copper carrier combining cuproptosis and photodynamic therapy for spatiotemporal synergistic anti-tumor therapy","volume":"13","author":"Hu","year":"2025","journal-title":"Biomater. Sci."},{"issue":"8","key":"10.1016\/j.mtbio.2026.103481_bib33","first-page":"2345","article-title":"Nanomedicine strategies for cuproptosis: Metabolic reprogramming and tumor immunotherapy","volume":"15","author":"Zhang","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.mtbio.2026.103481_bib34","article-title":"Biomimetic copper-doped polypyrrole nanoparticles induce glutamine metabolism inhibition to enhance breast cancer cuproptosis and immunotherapy","volume":"276","author":"Zhang","year":"2026","journal-title":"Pharmacol. Ther."},{"issue":"22","key":"10.1016\/j.mtbio.2026.103481_bib35","article-title":"Engineering nano-systems to elicit effective cuproptosis circumvent conventional small-molecule therapy constraints","volume":"13","author":"Lu","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib36","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12951-026-04331-3","article-title":"GSH-responsive triple-action photosensitizer nanoplatforms orchestrate cuproptosis-ferroptosis synergy to potentiate antitumor PDT efficacyd","volume":"24","author":"Xu","year":"2026","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.mtbio.2026.103481_bib37","first-page":"489","article-title":"A GSH-responsive polydopamine hybrid nanoparticle mediates dual GSH\/GPX4 depletion to amplify cuproptosis and enhance anti-PD-L1 immunotherapy in lung cance","volume":"167","author":"Zhang","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.mtbio.2026.103481_bib38","article-title":"Tumor-targeted redox-regulating and antiangiogenic phototherapeutics nanoassemblies for self-boosting phototherapy","volume":"297","author":"Jung","year":"2023","journal-title":"Biomaterials"},{"issue":"23","key":"10.1016\/j.mtbio.2026.103481_bib39","article-title":"Disulfide-bridged redox-responsive nanoplatforms as dual-function scaffolds and GSH scavengers for amplified tumor therapy","volume":"31","author":"Huang","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.mtbio.2026.103481_bib40","article-title":"MUC1 aptamer-functionalized chitosan nanoparticles for enhanced cancer therapy","volume":"203","author":"Hsu","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib41","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s40824-021-00244-4","article-title":"Design and clinical developments of aptamer-drug conjugates for targeted cancer therapy","volume":"25","author":"Kim","year":"2021","journal-title":"Biomater. Res."},{"issue":"43","key":"10.1016\/j.mtbio.2026.103481_bib42","doi-asserted-by":"crossref","first-page":"23299","DOI":"10.1002\/anie.202107347","article-title":"Aptamer-PROTAC conjugates (APCs) for tumor-specific targeting in breast cancer","volume":"60","author":"He","year":"2021","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.mtbio.2026.103481_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2023.1217769","article-title":"Anti-nucleolin aptamer AS1411: an advancing therapeutic","volume":"10","author":"Van den Avont","year":"2023","journal-title":"Front. Mol. Biosci."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib44","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/s42003-025-08101-z","article-title":"Copper-mediated SEC14L3 promotes cuproptosis to inhibit hepatocellular carcinoma growth via ERK\/YY1\/FDX1 axis","volume":"8","author":"Wu","year":"2025","journal-title":"Commun. Biol."},{"issue":"6","key":"10.1016\/j.mtbio.2026.103481_bib45","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.molcel.2013.06.001","article-title":"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways","volume":"50","author":"Park","year":"2013","journal-title":"Mol Cell"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib46","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s12943-024-02119-3","article-title":"Altered metabolism in cancer: insights into energy pathways and therapeutic targets","volume":"23","author":"Tufail","year":"2024","journal-title":"Mol. Cancer"},{"issue":"16","key":"10.1016\/j.mtbio.2026.103481_bib47","doi-asserted-by":"crossref","first-page":"7032","DOI":"10.7150\/thno.74197","article-title":"TCA-phospholipid-glycolysis targeted triple therapy effectively suppresses ATP production and tumor growth in glioblastoma","volume":"12","author":"Yang","year":"2022","journal-title":"Theranostics"},{"issue":"2","key":"10.1016\/j.mtbio.2026.103481_bib48","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1007\/s13238-017-0451-1","article-title":"The emerging role and targetability of the TCA cycle in cancer metabolism","volume":"9","author":"Anderson","year":"2018","journal-title":"Protein Cell"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib49","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/s41418-022-01051-7","article-title":"SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma","volume":"30","author":"Chen","year":"2023","journal-title":"Cell Death Differ."},{"issue":"48","key":"10.1016\/j.mtbio.2026.103481_bib50","doi-asserted-by":"crossref","first-page":"79981","DOI":"10.18632\/oncotarget.13210","article-title":"Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses","volume":"7","author":"Li","year":"2016","journal-title":"Oncotarget"},{"issue":"20","key":"10.1016\/j.mtbio.2026.103481_bib51","doi-asserted-by":"crossref","first-page":"13805","DOI":"10.1021\/jacs.3c14247","article-title":"Enzyme core spherical nucleic acid that enables enhanced cuproptosis and antitumor immune response through alleviating tumor hypoxia","volume":"146","author":"Huang","year":"2024","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.mtbio.2026.103481_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102789","article-title":"Novel insight into functions of ascorbate peroxidase in higher plants: more than a simple antioxidant enzyme","volume":"64","author":"Li","year":"2023","journal-title":"Redox Biol."},{"issue":"44","key":"10.1016\/j.mtbio.2026.103481_bib53","doi-asserted-by":"crossref","first-page":"30033","DOI":"10.1021\/jacs.4c06338","article-title":"Polyvalent aptamer nanodrug conjugates enable efficient tumor cuproptosis therapy through copper overload and glutathione depletion","volume":"146","author":"Wang","year":"2024","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103481_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/s41392-026-02583-x","article-title":"Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications","volume":"11","author":"Akter","year":"2026","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"5","key":"10.1016\/j.mtbio.2026.103481_bib55","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41422-022-00653-7","article-title":"Cuproptosis: a copper-triggered modality of mitochondrial cell death","volume":"32","author":"Tang","year":"2022","journal-title":"Cell Res."},{"issue":"12","key":"10.1016\/j.mtbio.2026.103481_bib56","article-title":"Mitochondrial ultrastructural remodeling during cuproptosis in renal cell carcinoma cells","volume":"239","author":"Li","year":"2024","journal-title":"J. Cell. Physiol."},{"issue":"19","key":"10.1016\/j.mtbio.2026.103481_bib57","article-title":"Cuproptosis-related mechanisms and therapeutic implications in cancer","volume":"29","author":"Chen","year":"2025","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.mtbio.2026.103481_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123794","article-title":"pH-responsive neutrophil membrane camouflage Ga-Mn bimetallic nanodecoy triggers apoptosis-immunity-metastasis suppression for tumor therapy","volume":"327","author":"Ma","year":"2026","journal-title":"Biomaterials"}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642600726X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S259000642600726X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:21:38Z","timestamp":1790335298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S259000642600726X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":58,"alternative-id":["S259000642600726X"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103481","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GSH-responsive self-assembled nanoplatform synergistically enhances cuproptosis through metabolic reprogramming and oxidative stress amplification","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103481","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103481"}}