{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T13:33:36Z","timestamp":1793453616008,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82374470"],"award-info":[{"award-number":["82374470"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82350710800"],"award-info":[{"award-number":["82350710800"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Municipal Science and Technology Program key projects","doi-asserted-by":"publisher","award":["2024A03J0660"],"award-info":[{"award-number":["2024A03J0660"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Municipal Science and Technology Program key projects","doi-asserted-by":"publisher","award":["2024A03J0673"],"award-info":[{"award-number":["2024A03J0673"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515220198"],"award-info":[{"award-number":["2023A1515220198"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515220173"],"award-info":[{"award-number":["2022A1515220173"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["KCXFZ20240903094059020"],"award-info":[{"award-number":["KCXFZ20240903094059020"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["SGDX20240115112400001"],"award-info":[{"award-number":["SGDX20240115112400001"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials Today Bio"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.mtbio.2026.103700","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:56:52Z","timestamp":1790135812000},"page":"103700","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Type II collagen as a material-mediated instructive platform: Cartilage regeneration and fibrosis suppression via the Tp63\u2013Cytl1 axis"],"prefix":"10.1016","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5548-7288","authenticated-orcid":false,"given":"Weicong","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiguang","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanshuo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2021-8309","authenticated-orcid":false,"given":"Jiake","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2588-344X","authenticated-orcid":false,"given":"Xiaohong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.mtbio.2026.103700_bib1","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.joca.2024.07.014","article-title":"Osteoarthritis year in review 2024: epidemiology and therapy","volume":"32","author":"Courties","year":"2024","journal-title":"Osteoarthr. Cartil."},{"issue":"9","key":"10.1016\/j.mtbio.2026.103700_bib2","first-page":"e508","article-title":"Global, regional, and national burden of osteoarthritis, 1990-2020 and projections to 2050: a systematic analysis for the global burden of disease study 2021, the Lancet","volume":"5","author":"Collaborators","year":"2023","journal-title":"Rheumatology"},{"issue":"16","key":"10.1016\/j.mtbio.2026.103700_bib3","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1001\/jama.2023.19675","article-title":"Evaluation and treatment of knee pain: a review","volume":"330","author":"Duong","year":"2023","journal-title":"JAMA"},{"issue":"13","key":"10.1016\/j.mtbio.2026.103700_bib4","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abk0011","article-title":"Stem cell-homing hydrogel-based miR-29b-5p delivery promotes cartilage regeneration by suppressing senescence in an osteoarthritis rat model","volume":"8","author":"Zhu","year":"2022","journal-title":"Sci. Adv."},{"issue":"10","key":"10.1016\/j.mtbio.2026.103700_bib5","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1038\/s41591-020-1013-2","article-title":"Articular cartilage regeneration by activated skeletal stem cells","volume":"26","author":"Murphy","year":"2020","journal-title":"Nat. Med."},{"issue":"5","key":"10.1016\/j.mtbio.2026.103700_bib6","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1089\/ten.teb.2022.0190","article-title":"Cartilage tissue engineering in practice: preclinical trials, clinical applications, and prospects","volume":"29","author":"Zhang","year":"2023","journal-title":"Tissue Eng. B Rev."},{"issue":"6","key":"10.1016\/j.mtbio.2026.103700_bib7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41584-024-01118-4","article-title":"Recent advancements in cartilage tissue engineering innovation and translation","volume":"20","author":"Nordberg","year":"2024","journal-title":"Nat. Rev. Rheumatol."},{"issue":"3","key":"10.1016\/j.mtbio.2026.103700_bib8","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.0632","article-title":"Effect of pulsed low-intensity ultrasonography on symptom relief and tibiofemoral articular cartilage thickness among veterans affairs enrollees with knee osteoarthritis: a randomized clinical trial","volume":"5","author":"Sawitzke","year":"2022","journal-title":"JAMA Netw. Open"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrrheum.2014.157","article-title":"Repair and tissue engineering techniques for articular cartilage","volume":"11","author":"Makris","year":"2015","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.mtbio.2026.103700_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.mser.2021.100641","article-title":"Collagen- and hyaluronic acid-based hydrogels and their biomedical applications","volume":"146","author":"Xu","year":"2021","journal-title":"Mater. Sci. Eng. R Rep."},{"key":"10.1016\/j.mtbio.2026.103700_bib11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.22203\/eCM.v047a17","article-title":"Unveiling the role of hypertrophic chondrocytes in abnormal cartilage calcification: insights into osteoarthritis mechanisms","volume":"47","author":"Zhou","year":"2024","journal-title":"Eur. Cell. Mater."},{"issue":"12","key":"10.1016\/j.mtbio.2026.103700_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2023.12.015","article-title":"3D-printed constructs deliver bioactive cargos to expedite cartilage regeneration","volume":"14","author":"Jiao","year":"2024","journal-title":"J. Pharm. Anal."},{"issue":"4","key":"10.1016\/j.mtbio.2026.103700_bib13","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1039\/D1BM01417J","article-title":"A highly porous type II collagen containing scaffold for the treatment of cartilage defects enhances MSC chondrogenesis and early cartilaginous matrix deposition","volume":"10","author":"Intini","year":"2022","journal-title":"Biomater. Sci."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/s43246-024-00598-x","article-title":"Type II collagen scaffolds for tissue engineering","volume":"5","author":"Hu","year":"2024","journal-title":"Commun. Mater."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib15","article-title":"An injectable and 3D printable pro-chondrogenic hyaluronic acid and collagen type II composite hydrogel for the repair of articular cartilage defects","volume":"16","author":"O'Shea","year":"2023","journal-title":"Biofabrication"},{"key":"10.1016\/j.mtbio.2026.103700_bib16","first-page":"364","article-title":"In situ implantation of type II collagen-based double-layer scaffolds for articular osteochondral regeneration comprising hyaline cartilage and vascularized subchondral bones","volume":"50","author":"Zhang","year":"2025","journal-title":"Bioact. Mater."},{"issue":"4","key":"10.1016\/j.mtbio.2026.103700_bib17","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3109\/03008207.2015.1026965","article-title":"Collagen II regulates chondroycte integrin expression profile and differentiation","volume":"56","author":"Xin","year":"2015","journal-title":"Connect. Tissue Res."},{"issue":"4","key":"10.1016\/j.mtbio.2026.103700_bib18","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1074\/jbc.270.4.1747","article-title":"A COL2A1 mutation in achondrogenesis type II results in the replacement of type II collagen by type I and III collagens in cartilage","volume":"270","author":"Chan","year":"1995","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.mtbio.2026.103700_bib19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/jbm.b.31762","article-title":"MRI and histologic analysis of collagen type II sponge on repairing the cartilage defects of rabbit knee joints","volume":"96","author":"Chen","year":"2011","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"3\u20134","key":"10.1016\/j.mtbio.2026.103700_bib20","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1089\/ten.tea.2020.0107","article-title":"Construction and evaluation of osteochondral-like tissue using chondrocyte sheet and cancellous bone","volume":"27","author":"Wongin","year":"2021","journal-title":"Tissue Eng Part A"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib21","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1038\/s41467-025-57684-y","article-title":"Radial glia integrin avb8 regulates cell autonomous microglial TGF\u03b21 signaling that is necessary for microglial identity","volume":"16","author":"McKinsey","year":"2025","journal-title":"Nat. Commun."},{"issue":"9","key":"10.1016\/j.mtbio.2026.103700_bib22","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1111\/jcmm.13104","article-title":"Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes","volume":"21","author":"Yang","year":"2017","journal-title":"J. Cell Mol. Med."},{"issue":"3","key":"10.1016\/j.mtbio.2026.103700_bib23","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.bbrc.2020.06.069","article-title":"The involvement of cytokine-like 1 (Cytl1) in chondrogenesis and cartilage metabolism","volume":"529","author":"Zhu","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mtbio.2026.103700_bib24","article-title":"Type II collagen sponges facilitate tendon stem\/progenitor cells to adopt more chondrogenic phenotypes and promote the regeneration of fibrocartilage-like tissues in a rabbit partial patellectomy model","volume":"9","author":"Wang","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.mtbio.2026.103700_bib25","article-title":"Effect of tragacanth gum on physical and mechanical properties of fish collagen sponge for hemostatic dressing applications","volume":"13","author":"Siaghi","year":"2026","journal-title":"Carbohydr. Polym. Technol. Appl."},{"key":"10.1016\/j.mtbio.2026.103700_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119548","article-title":"Hierarchical microchanneled scaffolds modulate multiple tissue-regenerative processes of immune-responses, angiogenesis, and stem cell homing","volume":"227","author":"Won","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.103700_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2022.121707","article-title":"Oral delivery of IL-22 mRNA-loaded lipid nanoparticles targeting the injured intestinal mucosa: a novel therapeutic solution to treat ulcerative colitis","volume":"288","author":"Sung","year":"2022","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.mtbio.2026.103700_bib28","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1136\/annrheumdis-2020-219760","article-title":"Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis","volume":"80","author":"Steinberg","year":"2021","journal-title":"Ann. Rheum. Dis."},{"issue":"8 suppl 1","key":"10.1016\/j.mtbio.2026.103700_bib29","doi-asserted-by":"crossref","first-page":"S153","DOI":"10.1074\/mcp.TIR118.001251","article-title":"MOGSA: integrative single sample gene-set analysis of multiple omics data","volume":"18","author":"Meng","year":"2019","journal-title":"Mol. Cell. Proteomics : MCP"},{"key":"10.1016\/j.mtbio.2026.103700_bib30","article-title":"The organizational principles of de-differentiated topographic maps in somatosensory cortex","volume":"10","author":"Liu","year":"2021","journal-title":"eLife"},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib31","doi-asserted-by":"crossref","DOI":"10.1002\/biot.202300031","article-title":"Lentivirus\u2010based shRNA of Caspase\u20103 gene silencing inhibits chondrocyte apoptosis and delays the progression of surgically induced osteoarthritis","volume":"19","author":"Zhu","year":"2024","journal-title":"Biotechnol. J."},{"issue":"3","key":"10.1016\/j.mtbio.2026.103700_bib32","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.knee.2010.04.010","article-title":"The histological features of anteromedial gonarthrosis--the comparison of two grading systems in a human phenotype of osteoarthritis","volume":"18","author":"Rout","year":"2011","journal-title":"Knee"},{"issue":"5","key":"10.1016\/j.mtbio.2026.103700_bib33","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/ajcp\/65.5.715","article-title":"Celestine blue B stain for intestinal protozoa","volume":"65","author":"Yang","year":"1976","journal-title":"Am. J. Clin. Pathol."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib34","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3109\/10520298109067273","article-title":"A hematoxylin and eosin-like stain for glycol methacrylate embedded tissue sections","volume":"56","author":"Troyer","year":"1981","journal-title":"Stain Technol."},{"issue":"8","key":"10.1016\/j.mtbio.2026.103700_bib35","doi-asserted-by":"crossref","first-page":"11433","DOI":"10.18632\/aging.202833","article-title":"Overexpression of long non-coding RNA AP001505.9 inhibits human hyaline chondrocyte dedifferentiation","volume":"13","author":"Chen","year":"2021","journal-title":"Aging"},{"key":"10.1016\/j.mtbio.2026.103700_bib36","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41413-019-0046-y","article-title":"Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin \u03b21-SMAD1 interaction","volume":"7","author":"Lian","year":"2019","journal-title":"Bone Res."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib37","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41536-025-00425-y","article-title":"Prx1+ progenitors give rise to new articular cartilage when conditions are permissive for endogenous regeneration","volume":"10","author":"Jablonski","year":"2025","journal-title":"npj Regen. Med."},{"issue":"5430","key":"10.1016\/j.mtbio.2026.103700_bib38","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1126\/science.285.5430.1028","article-title":"Integrin signaling","volume":"285","author":"Giancotti","year":"1999","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.mtbio.2026.103700_bib39","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev-cellbio-092910-154013","article-title":"Transmembrane collagen receptors","volume":"27","author":"Leitinger","year":"2011","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.mtbio.2026.103700_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123393","article-title":"A multi-gradient organoid of articular cartilage with bionic matrix microenvironment","volume":"322","author":"Wu","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.mtbio.2026.103700_bib41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.addr.2015.11.013","article-title":"Collagen interactions: drug design and delivery","volume":"97","author":"An","year":"2016","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41413-021-00182-w","article-title":"The collagen receptor, discoidin domain receptor 2, functions in Gli1-positive skeletal progenitors and chondrocytes to control bone development","volume":"10","author":"Mohamed","year":"2022","journal-title":"Bone Res."},{"issue":"18","key":"10.1016\/j.mtbio.2026.103700_bib43","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1007\/s00018-019-03137-x","article-title":"Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease","volume":"76","author":"Zhu","year":"2019","journal-title":"Cell Mol Life Sci."},{"issue":"40","key":"10.1016\/j.mtbio.2026.103700_bib44","doi-asserted-by":"crossref","first-page":"29359","DOI":"10.1074\/jbc.M700965200","article-title":"Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells","volume":"282","author":"Kim","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.mtbio.2026.103700_bib45","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/s41392-021-00856-1","article-title":"Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer","volume":"7","author":"Xue","year":"2022","journal-title":"Signal Transduct Target Ther"},{"issue":"6729","key":"10.1016\/j.mtbio.2026.103700_bib46","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/19531","article-title":"p63 is a p53 homologue required for limb and epidermal morphogenesis","volume":"398","author":"Mills","year":"1999","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.mtbio.2026.103700_bib47","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1002\/art.39976","article-title":"Regulation of chondrocyte survival in mouse articular cartilage by p63","volume":"69","author":"Taniguchi","year":"2017","journal-title":"Arthritis Rheumatol."},{"issue":"9","key":"10.1016\/j.mtbio.2026.103700_bib48","doi-asserted-by":"crossref","first-page":"8669","DOI":"10.18632\/aging.103190","article-title":"TAp63\u03b3 influences mouse cartilage development","volume":"12","author":"Wang","year":"2020","journal-title":"Aging"},{"issue":"11","key":"10.1016\/j.mtbio.2026.103700_bib49","doi-asserted-by":"crossref","first-page":"7525","DOI":"10.1111\/jcmm.14621","article-title":"NOV\/CCN3 induces cartilage protection by inhibiting PI3K\/AKT\/mTOR pathway","volume":"23","author":"Huang","year":"2019","journal-title":"J. Cell Mol. Med."},{"issue":"8024","key":"10.1016\/j.mtbio.2026.103700_bib50","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/s41586-024-07634-3","article-title":"A maternal brain hormone that builds bone","volume":"632","author":"Babey","year":"2024","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.mtbio.2026.103700_bib51","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1136\/annrheumdis-2017-212603","article-title":"Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage","volume":"77","author":"Soul","year":"2018","journal-title":"Ann. Rheum. Dis."}],"container-title":["Materials Today Bio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426009452?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590006426009452?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:49:00Z","timestamp":1793450940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590006426009452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":51,"alternative-id":["S2590006426009452"],"URL":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103700","relation":{},"ISSN":["2590-0064"],"issn-type":[{"value":"2590-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Type II collagen as a material-mediated instructive platform: Cartilage regeneration and fibrosis suppression via the Tp63\u2013Cytl1 axis","name":"articletitle","label":"Article Title"},{"value":"Materials Today Bio","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mtbio.2026.103700","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103700"}}