{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:46:34Z","timestamp":1791337594255,"version":"4.3.1"},"reference-count":71,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI123371"],"award-info":[{"award-number":["AI123371"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI159507"],"award-info":[{"award-number":["AI159507"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["mucosalimmunology.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mucosal Immunology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.mucimm.2023.03.004","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T22:10:08Z","timestamp":1679609408000},"page":"302-311","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Novel neuroendocrine role of \u03b3-aminobutyric acid and gastrin-releasing peptide in the host response to influenza infection"],"prefix":"10.1016","volume":"16","author":[{"given":"Kari Ann","family":"Shirey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E","family":"Sunday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Cuttitta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge C.G.","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie N.","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mucimm.2023.03.004_b0005","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/s41577-019-0147-2","article-title":"Pain and immunity: implications for host defense","volume":"19","author":"Baral","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0010","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nrd2280","article-title":"The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-on-concept","volume":"6","author":"Szallasi","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.mucimm.2023.03.004_b0015","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.tins.2019.05.005","article-title":"Neuronal regulation of immunity in the skin and lungs","volume":"42","author":"Blake","year":"2019","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.mucimm.2023.03.004_b0020","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.immuni.2020.02.017","article-title":"Neuro-immune interactions in the tissues","volume":"52","author":"Chu","year":"2020","journal-title":"Immunity."},{"key":"10.1016\/j.mucimm.2023.03.004_b0025","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1164\/ajrccm.154.3.8810616","article-title":"Number and proliferation of neuroendocrine cells in normal human airway epithelium","volume":"154","author":"Boers","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.mucimm.2023.03.004_b0030","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1126\/science.aad7969","article-title":"Pulmonary neuroendocrine cells function as airway sensors to control lung immune responses","volume":"351","author":"Branchfield","year":"2016","journal-title":"Science."},{"key":"10.1016\/j.mucimm.2023.03.004_b0035","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41577-020-00477-9","article-title":"Regulation of immune responses by airway epithelial cell landscape","volume":"21","author":"Hewitt","year":"2021","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0040","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1136\/gut.19.9.767","article-title":"A gastrin releasing peptide from the porcine nonantral gastric tissue","volume":"19","author":"McDonald","year":"1978","journal-title":"Gut."},{"key":"10.1016\/j.mucimm.2023.03.004_b0045","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0006-291X(79)91614-0","article-title":"Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue","volume":"90","author":"McDonald","year":"1979","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mucimm.2023.03.004_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1124\/pr.107.07108","article-title":"Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states","volume":"60","author":"Jensen, R.T., Battey, J.F., Spindel, E.R. & Benya, R.V. International Union of Pharmacology. LXVIII","year":"2008","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.mucimm.2023.03.004_b0055","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.peptides.2015.04.026","article-title":"Insights into bombesin receptors and ligands: highlighting recent advances","volume":"72","author":"Ramos-\u00c1lvarez","year":"2015","journal-title":"Peptides."},{"key":"10.1016\/j.mucimm.2023.03.004_b0060","doi-asserted-by":"crossref","DOI":"10.1177\/1010428317694321","article-title":"Neuropeptide gastrin-releasing peptide induces PI3K\/reactive oxygen species-dependent migration in lung adenocarcinoma cells","volume":"39","author":"Jaeger","year":"2017","journal-title":"Tumour Biol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0065","first-page":"72","article-title":"Oxygen, gastrin-releasing peptide, and pediatric lung disease: life in the balance","volume":"2","author":"Sunday","year":"2014","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.mucimm.2023.03.004_b0070","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0024-3205(94)00481-7","article-title":"BW2258U89: a GRP receptor antagonist which inhibits small cell lung cancer growth","volume":"56","author":"Moody","year":"1995","journal-title":"Life Sci."},{"key":"10.1016\/j.mucimm.2023.03.004_b0075","unstructured":"Influenza (seasonal). Available at: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/influenza-(seasonal) (2022) [Date accessed: 05\/10\/2022]."},{"key":"10.1016\/j.mucimm.2023.03.004_b0080","unstructured":"Centers for Disease Control and Prevention. Available at: https:\/\/www.cdc.gov\/flu\/about\/burden\/preliminary-in-season-estimates.html (2022) [Date accessed: 05\/10\/2022]."},{"key":"10.1016\/j.mucimm.2023.03.004_b0085","first-page":"119","volume":"62","year":"2013","journal-title":"Morb. Mortal. Wkly Rep."},{"key":"10.1016\/j.mucimm.2023.03.004_b0090","first-page":"366","volume":"62","year":"2013","journal-title":"Morb. Mortal. Wkly Rep."},{"key":"10.1016\/j.mucimm.2023.03.004_b0095","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41385-018-0081-9","article-title":"Novel role of gastrin releasing peptide-mediated signaling in the host response to influenza infection","volume":"12","author":"Shirey","year":"2019","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0100","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1159\/000007462","article-title":"Regulation of gastrin, somatostatin, and bombesin release from the isolated rat stomach by exogenous and endogenous gamma-aminobutyric acid","volume":"59","author":"Weigert","year":"1998","journal-title":"Digestion"},{"key":"10.1016\/j.mucimm.2023.03.004_b0105","doi-asserted-by":"crossref","first-page":"10272","DOI":"10.1038\/s41598-018-28538-z","article-title":"GABA promotes gastrin-releasing peptide secretion in NE\/NE-like cells: contribution to prostrate cancer progression","volume":"8","author":"Solorzano","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mucimm.2023.03.004_b0110","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cell.2008.02.043","article-title":"Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury","volume":"133","author":"Imai","year":"2008","journal-title":"Cell."},{"key":"10.1016\/j.mucimm.2023.03.004_b0115","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.micinf.2017.08.008","article-title":"The role of oxidative stress in influenza infection","volume":"19","author":"Liu","year":"2017","journal-title":"Microbes Infect."},{"key":"10.1016\/j.mucimm.2023.03.004_b0120","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.2174\/1568026614666141203125211","article-title":"Intracellular redox state as a target for anti-influenza therapy: are antioxidants always effective?","volume":"14","author":"Sgarbanti","year":"2014","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.mucimm.2023.03.004_b0125","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.705080","article-title":"Targeting TLR4 signaling to blunt viral-mediated acute lung injury","volume":"12","author":"Shirey","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0130","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12118","article-title":"The TLR4 antagonist Eritoran protects mice from lethal influenza infection","volume":"497","author":"Shirey","year":"2013","journal-title":"Nature."},{"key":"10.1016\/j.mucimm.2023.03.004_b0135","doi-asserted-by":"crossref","first-page":"3088","DOI":"10.21037\/jtd.2018.05.92","article-title":"Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens","volume":"10","author":"Cui","year":"2018","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.mucimm.2023.03.004_b0140","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/s41390-019-0464-y","article-title":"Oxidative stress markers in neonatal respiratory distress syndrome: advanced oxidative protein product and 8-hydroxy-2-deoxyguanosine in relation to disease severity","volume":"87","author":"Elkabany","year":"2020","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.mucimm.2023.03.004_b0145","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.biopha.2017.02.081","article-title":"Kaempferol ameliorates H9N2 swine influenza virus-induced acute lung injury by inactivation of TLR4\/MyD88-mediated NF-kB and MAPK signaling pathways","volume":"89","author":"Zhang","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.mucimm.2023.03.004_b0150","article-title":"Influenza-induced oxidative stress sensitizes lung cells to bacterial-toxin-mediated necroptosis","volume":"8","author":"Gonzalez-Juarbe","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.mucimm.2023.03.004_b0155","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3389\/fimmu.2014.00561","article-title":"Therapeutic impact of human serum albumin-thioredoxin fusion protein on influenza virus-induced lung injury mice","volume":"5","author":"Tanaka","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0160","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.freeradbiomed.2013.10.014","article-title":"Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice","volume":"67","author":"Kash","year":"2014","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mucimm.2023.03.004_b0165","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/BF00220210","article-title":"Ultrastructure and fluorescence histochemistry of endocrine (APUD-type) cells in tracheal mucosa of human and various animal species","volume":"158","author":"Cutz","year":"1975","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.mucimm.2023.03.004_b0170","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/01902148209069653","article-title":"Neuroendocrine cells of the lung and overview of morphologic characteristics and development","volume":"3","author":"Cutz","year":"1982","journal-title":"Exp. Lung Res."},{"key":"10.1016\/j.mucimm.2023.03.004_b0175","doi-asserted-by":"crossref","first-page":"419","DOI":"10.2350\/07-04-0267.1","article-title":"Pulmonary neuroendocrine cell system in pediatric lung disease-recent advances","volume":"10","author":"Cutz","year":"2007","journal-title":"Pediatr. Dev. Pathol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0180","first-page":"171","article-title":"Pulmonary neuroendocrine cells (PNEC) and neuroepithelial bodies (NEB): chemoreceptors and regulators of lung development","volume":"2","author":"Van Lommel","year":"2001","journal-title":"Paediatr. Respir. Rev."},{"key":"10.1016\/j.mucimm.2023.03.004_b0185","doi-asserted-by":"crossref","first-page":"4117","DOI":"10.1096\/fj.201700115R","article-title":"Early life allergen-induced mucus overproduction requires augmented neural stimulation of pulmonary neuroendocrine cell secretion","volume":"31","author":"Barrios","year":"2017","journal-title":"FASEB J."},{"key":"10.1016\/j.mucimm.2023.03.004_b0190","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1210\/en.2003-1251","article-title":"Identification of vasoactive nonpeptide positive and negative modulators of adrenomedulin using a neutralizing antibody-based screening strategy","volume":"145","author":"Mart\u00ednez","year":"2004","journal-title":"Endocrinology."},{"key":"10.1016\/j.mucimm.2023.03.004_b0195","doi-asserted-by":"crossref","first-page":"4106","DOI":"10.1038\/sj.onc.1208581","article-title":"Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo","volume":"24","author":"Mart\u00ednez","year":"2005","journal-title":"Oncogene."},{"key":"10.1016\/j.mucimm.2023.03.004_b0200","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.ajpath.2019.01.017","article-title":"Immediate release of gastrin-releasing peptide mediates delayed radiation-induced pulmonary fibrosis","volume":"189","author":"Tighe","year":"2019","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0205","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/316823a0","article-title":"Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer","volume":"316","author":"Cuttitta","year":"1985","journal-title":"Nature."},{"key":"10.1016\/j.mucimm.2023.03.004_b0210","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12868-016-0251-1","article-title":"Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury","volume":"17","author":"Cao","year":"2016","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.mucimm.2023.03.004_b0215","doi-asserted-by":"crossref","first-page":"6108","DOI":"10.1093\/cercor\/bhaa157","article-title":"Increase in seizure susceptibility after repetitive concussion results from oxidative stress, parvalbumin-positive interneuron dysfunction and biphasic increases in glutamate\/GABA ratio","volume":"30","author":"MacMullin","year":"2020","journal-title":"Cereb. Cortex."},{"key":"10.1016\/j.mucimm.2023.03.004_b0220","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3390\/antiox10081316","article-title":"The alteration of chloride homeostasis\/GABAergic signaling in brain disorders: could oxidative stress play a role?","volume":"10","author":"Abruzzo","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.mucimm.2023.03.004_b0225","doi-asserted-by":"crossref","first-page":"dmm046920","DOI":"10.1242\/dmm.046920","article-title":"Pulmonary neuroendocrine cells: physiology, tissue homeostasis and disease","volume":"13","author":"Noguchi","year":"2020","journal-title":"Dis. Model Mech."},{"key":"10.1016\/j.mucimm.2023.03.004_b0230","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s12272-019-01196-z","article-title":"The regulation of glutamic acid decarboxylases in GABA neurotransmission in the brain","volume":"42","author":"Lee","year":"2019","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.mucimm.2023.03.004_b0235","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s11011-014-9560-1","article-title":"GABA receptor in brain development, function, and injury","volume":"30","author":"Wu","year":"2015","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.mucimm.2023.03.004_b0240","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0304-3940(90)90503-2","article-title":"Inhibition of Baclofen binding to rat cerebellar membranes by phaclofen, saclofen, 3-aminopropylphosphonic acid and related GABAB receptor antagonists","volume":"113","author":"Drew","year":"1990","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.mucimm.2023.03.004_b0245","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/mi.2015.141","article-title":"Novel strategies for targeting innate immune responses to influenza","volume":"9","author":"Shirey","year":"2016","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0250","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/088307380101600106","article-title":"Pharmacotherapy of spacity: oral medication and intrathecal Baclofen","volume":"16","author":"Krach","year":"2001","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0255","doi-asserted-by":"crossref","first-page":"e00810","DOI":"10.1128\/mBio.00810-19","article-title":"Influenza \u201ctrains\u201d the host for enhanced susceptibility to secondary bacterial infection","volume":"10","author":"Shirey","year":"2019","journal-title":"mBio."},{"key":"10.1016\/j.mucimm.2023.03.004_b0260","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1164\/ajrccm.149.6.7911710","article-title":"Determinants of susceptibility to cigarette smoke. Potential roles for neuroendocrine cells and neuropeptides in airway inflammation, airway wall remodeling, and chronic airflow obstruction","volume":"149","author":"Aguayo","year":"1994","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.mucimm.2023.03.004_b0265","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1073\/pnas.1110996109","article-title":"Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils","volume":"109","author":"Czepielewski","year":"2012","journal-title":"Proc. Natl Acad. Sci. U. S. A."},{"key":"10.1016\/j.mucimm.2023.03.004_b0270","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.4049\/jimmunol.180.4.2562","article-title":"CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality","volume":"180","author":"Lin","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0275","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12929-014-0099-6","article-title":"The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection","volume":"21","author":"Lin","year":"2014","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.mucimm.2023.03.004_b0280","doi-asserted-by":"crossref","first-page":"e00030","DOI":"10.1128\/JVI.00030-19","article-title":"PPAR-g in macrophages limits pulmonary inflammation and promotes host recovery following respiratory viral infection","volume":"93","author":"Huang","year":"2019","journal-title":"J. Virol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0285","doi-asserted-by":"crossref","first-page":"e0124622","DOI":"10.1128\/jvi.01246-22","article-title":"Cellular heterogeneity and molecular reprogramming of the host response during influenza acute lung injury","volume":"96","author":"Guo","year":"2022","journal-title":"J. Virol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0290","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1084\/jem.20141318","article-title":"MD-2 is required for disulfide HMGB1-dependent TLR4 signaling","volume":"212","author":"Yang","year":"2015","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.mucimm.2023.03.004_b0295","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/JLB.3RU0121-023R","article-title":"Neuroimmune regulatory networks of the airway mucosa in allergic inflammatory disease","volume":"111","author":"Jean","year":"2022","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0300","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00408-015-9832-5","article-title":"Airway vagal neuroplasticity associated with repiratory viral infections","volume":"194","author":"Zaccone","year":"2016","journal-title":"Lung."},{"key":"10.1016\/j.mucimm.2023.03.004_b0305","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1099\/vir.0.81145-0","article-title":"The cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis","volume":"86","author":"Ottolini","year":"2005","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0310","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1165\/rcmb.2018-0179OC","article-title":"Pulmonary neuroendocrine cells secrete g-aminobutyric acid to induce goblet cell hyperplasia in primate models","volume":"60","author":"Barrios","year":"2018","journal-title":"Am. J. Cell Mol. Biol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0315","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0006-291X(02)00355-8","article-title":"Functional GABAB receptors expressed in cultured calvarial osteoblasts","volume":"293","author":"Argil\u00e9s","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mucimm.2023.03.004_b0320","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0006-8993(96)00120-5","article-title":"Evidence for pharmacologically distinct GABAB receptor associated with cAMP production in rat brain","volume":"720","author":"Cunningham","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.mucimm.2023.03.004_b0325","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1006\/mcne.2000.0908","article-title":"GABAB receptors: a new paradigm in G protein signalling","volume":"16","author":"Couve","year":"2000","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.mucimm.2023.03.004_b0330","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1046\/j.1365-2222.1998.00289.x","article-title":"Role of GABA receptors in the bronchial response: studies in sensitized guinea-pigs","volume":"28","author":"Tohda","year":"1998","journal-title":"Clin. Exp. Allergy."},{"key":"10.1016\/j.mucimm.2023.03.004_b0335","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0952-0600(91)90014-T","article-title":"Prejunctional GABA-B inhibition of cholinergic, neurally-mediated airway contractions in guinea-pigs","volume":"4","author":"Chapman","year":"1991","journal-title":"Pulm. Pharmacol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0340","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/pupt.1999.0205","article-title":"Effect of the GABA-agonist Baclofen on bronchial responsiveness in asthmatics","volume":"12","author":"Dicpinigaitis","year":"1999","journal-title":"Pulm. Pharmacol. Ther."},{"key":"10.1016\/j.mucimm.2023.03.004_b0345","doi-asserted-by":"crossref","first-page":"6834","DOI":"10.4049\/jimmunol.0803860","article-title":"Costimulation modulation uncouples protection from immunopathology in memory T cell response to influenza virus","volume":"182","author":"Teijaro","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0350","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.4049\/jimmunol.181.6.4159","article-title":"Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism","volume":"181","author":"Shirey","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.mucimm.2023.03.004_b0355","doi-asserted-by":"crossref","first-page":"68888","DOI":"10.4049\/jimmunol.176.11.6888","article-title":"Immunological consequences of Francisella tularensis live vaccine strain infection: role of the innate immune response in infection and immunity","volume":"176","author":"Cole","year":"2006","journal-title":"J. Immunol."}],"container-title":["Mucosal Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193302192300020X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193302192300020X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:31:13Z","timestamp":1761831073000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193302192300020X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":71,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S193302192300020X"],"URL":"https:\/\/doi.org\/10.1016\/j.mucimm.2023.03.004","relation":{},"ISSN":["1933-0219"],"issn-type":[{"value":"1933-0219","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel neuroendocrine role of \u03b3-aminobutyric acid and gastrin-releasing peptide in the host response to influenza infection","name":"articletitle","label":"Article Title"},{"value":"Mucosal Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mucimm.2023.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc. on behalf of Society for Mucosal Immunology.","name":"copyright","label":"Copyright"}]}}