{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T19:05:17Z","timestamp":1784747117525,"version":"3.55.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006492","name":"National Institute of Allergy and Infectious Diseases Division of Intramural Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100024057","name":"School of Medicine and Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100024057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017540","name":"Division of Intramural Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017540","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019659","name":"The George Washington University School of Medicine and Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","mucosalimmunology.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mucosal Immunology"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.mucimm.2026.01.005","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:44:38Z","timestamp":1768610678000},"page":"1848-1861","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["IL-11 acts as an alarmin-like pro-inflammatory mediator regulating mucosal responses during helminth infection"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4932-2206","authenticated-orcid":false,"given":"Pedro H.","family":"Gazzinelli-Guimaraes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8514-2405","authenticated-orcid":false,"given":"Pablo","family":"Bara-Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7276-7898","authenticated-orcid":false,"given":"Jonah","family":"Kupritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabricio Marcus","family":"Silva Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Queiroz-Glauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7935-755X","authenticated-orcid":false,"given":"Byunghyun","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Makiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6887-4941","authenticated-orcid":false,"given":"Thomas B.","family":"Nutman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mucimm.2026.01.005_b0005","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1146\/annurev.immunol.15.1.797","article-title":"Gp130 and the interleukin-6 family of cytokines","volume":"15","author":"Taga","year":"1997","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2021.155750","article-title":"Emerging roles for IL-11 in inflammatory diseases","volume":"149","author":"Fung","year":"2022","journal-title":"Cytokine"},{"key":"10.1016\/j.mucimm.2026.01.005_b0015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.55563\/clinexprheumatol\/mccyj0","article-title":"Increased interleukin-11 associated with disease activity and development of interstitial lung disease in patients with rheumatoid arthritis","volume":"40","author":"Wang","year":"2022","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0020","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1111\/1346-8138.16854","article-title":"Elevated interleukin-11 in systemic sclerosis and role in disease pathogenesis","volume":"50","author":"Steadman","year":"2023","journal-title":"J Dermatol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0025","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.1093\/rheumatology\/keab168","article-title":"IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFbeta-mediated activation of dermal fibroblasts","volume":"60","author":"Adami","year":"2021","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.mucimm.2026.01.005_b0030","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12865-018-0257-9","article-title":"The expression analysis of Fra-1 gene and IL-11 protein in iranian patients with ulcerative colitis","volume":"19","author":"Sabzevary-Ghahfarokhi","year":"2018","journal-title":"BMC Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0035","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1002\/ibd.21301","article-title":"Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease","volume":"16","author":"Arijs","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.mucimm.2026.01.005_b0040","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.cell.2019.06.029","article-title":"Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis","volume":"178","author":"Smillie","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.mucimm.2026.01.005_b0045","doi-asserted-by":"crossref","first-page":"7497","DOI":"10.1038\/s41467-022-35306-1","article-title":"Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease","volume":"13","author":"Widjaja","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.mucimm.2026.01.005_b0050","article-title":"IL-11 Attenuates Liver Ischemia\/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in mice","volume":"10","author":"Zhu","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.mucimm.2026.01.005_b0055","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/hep.510300616","article-title":"Interleukin-11 reduces T-cell-dependent experimental liver injury in mice","volume":"30","author":"Bozza","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.mucimm.2026.01.005_b0060","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1080\/019262301317052521","article-title":"Protective effect of rhIL-11 in a murine model of acetaminophen-induced hepatotoxicity","volume":"29","author":"Trepicchio","year":"2001","journal-title":"Toxicol Pathol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0065","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1146\/annurev-med-041818-011649","article-title":"Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation","volume":"71","author":"Cook","year":"2020","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.mucimm.2026.01.005_b0070","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1465-9921-14-80","article-title":"Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease","volume":"14","author":"Lindahl","year":"2013","journal-title":"Respir Res"},{"key":"10.1016\/j.mucimm.2026.01.005_b0075","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0091-6749(00)90070-8","article-title":"IL-11 expression is increased in severe asthma: association with epithelial cells and eosinophils","volume":"105","author":"Minshall","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0080","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaw1237","article-title":"Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis","volume":"11","author":"Ng","year":"2019","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.mucimm.2026.01.005_b0085","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/s41586-024-07701-9","article-title":"Inhibition of IL-11 signalling extends mammalian healthspan and lifespan","volume":"632","author":"Widjaja","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.mucimm.2026.01.005_b0090","doi-asserted-by":"crossref","unstructured":"Gazzinelli-Guimaraes, P. H. & Nutman, T. B. Helminth parasites and immune regulation. F1000Res 7 (2018). https:\/\/doi.org\/10.12688\/f1000research.15596.1.","DOI":"10.12688\/f1000research.15596.1"},{"key":"10.1016\/j.mucimm.2026.01.005_b0095","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1172\/JCI34261","article-title":"Helminth infections: the great neglected tropical diseases","volume":"118","author":"Hotez","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mucimm.2026.01.005_b0100","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.594520","article-title":"Host Immunity and Inflammation to Pulmonary Helminth Infections","volume":"11","author":"Weatherhead","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0010050","article-title":"Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice","volume":"15","author":"Wu","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.mucimm.2026.01.005_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2023.106483","article-title":"The long-lasting Ascaris suum antigens in the lungs shapes the tissue adaptation modifying the pulmonary architecture and immune response after infection in mice","volume":"186","author":"Oliveira","year":"2024","journal-title":"Microb Pathog"},{"key":"10.1016\/j.mucimm.2026.01.005_b0115","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s40249-022-01038-z","article-title":"Global prevalence of Ascaris infection in humans (2010-2021): a systematic review and meta-analysis","volume":"11","author":"Holland","year":"2022","journal-title":"Infect Dis Poverty"},{"key":"10.1016\/j.mucimm.2026.01.005_b0120","doi-asserted-by":"crossref","first-page":"e1074","DOI":"10.1002\/cpz1.1074","article-title":"Ascaris Mouse Model Protocols: advancing Research on Larval Ascariasis Biology","volume":"4","author":"de Almeida Lopes","year":"2024","journal-title":"Curr Protoc"},{"key":"10.1016\/j.mucimm.2026.01.005_b0125","article-title":"Immunological underpinnings of Ascaris infection, reinfection and co-infection and their associated co-morbidities","volume":"1\u201310","author":"Magalhaes","year":"2021","journal-title":"Parasitology"},{"key":"10.1016\/j.mucimm.2026.01.005_b0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009337","article-title":"House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins","volume":"17","author":"Gazzinelli-Guimaraes","year":"2021","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.mucimm.2026.01.005_b0135","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1172\/JCI127963","article-title":"Allergen presensitization drives an eosinophil-dependent arrest in lung-specific helminth development","volume":"129","author":"Gazzinelli-Guimaraes","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.mucimm.2026.01.005_b0140","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ijpara.2013.02.009","article-title":"Parasitological and immunological aspects of early Ascaris spp. infection in mice","volume":"43","author":"Gazzinelli-Guimaraes","year":"2013","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004382","article-title":"Multiple Exposures to Ascaris suum Induce Tissue Injury and mixed Th2\/Th17 Immune Response in mice","volume":"10","author":"Nogueira","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.mucimm.2026.01.005_b0150","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.pt.2017.12.007","article-title":"Helminth Modulation of Lung Inflammation","volume":"34","author":"Schwartz","year":"2018","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0155","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1038\/ni.3023","article-title":"Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage","volume":"15","author":"Sutherland","year":"2014","journal-title":"Nat Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0160","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cyto.2011.01.007","article-title":"IL-6 plays an essential role in neutrophilia under inflammation","volume":"54","author":"Hashizume","year":"2011","journal-title":"Cytokine"},{"key":"10.1016\/j.mucimm.2026.01.005_b0165","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.4049\/jimmunol.181.3.2189","article-title":"IL-6 regulates neutrophil trafficking during acute inflammation via STAT3","volume":"181","author":"Fielding","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0170","doi-asserted-by":"crossref","first-page":"22261","DOI":"10.1016\/S0021-9258(17)31785-4","article-title":"Epithelial interleukin-11. Regulation by cytokines, respiratory syncytial virus, and retinoic acid","volume":"269","author":"Elias","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.mucimm.2026.01.005_b0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0221029","article-title":"Roles of interleukin-11 during acute bacterial pneumonia","volume":"14","author":"Traber","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.mucimm.2026.01.005_b0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021878","article-title":"Interleukin-11 drives early lung inflammation during Mycobacterium tuberculosis infection in genetically susceptible mice","volume":"6","author":"Kapina","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.mucimm.2026.01.005_b0185","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/infdis\/jiw176","article-title":"Therapeutic effect of Recombinant Mutated Interleukin 11 in the Mouse Model of Tuberculosis","volume":"214","author":"Shepelkova","year":"2016","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mucimm.2026.01.005_b0190","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1038\/s12276-020-00531-5","article-title":"Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway","volume":"52","author":"Ng","year":"2020","journal-title":"Exp Mol Med"},{"key":"10.1016\/j.mucimm.2026.01.005_b0195","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23168900","article-title":"IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues","volume":"23","author":"Widjaja","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.mucimm.2026.01.005_b0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrcardio.2017.197","article-title":"Cardioprotection: IL-11 is a potential therapeutic target in cardiovascular fibrosis","volume":"15","author":"Fernandez-Ruiz","year":"2018","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0205","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1681\/ASN.2021040577","article-title":"A Neutralizing IL-11 Antibody Improves Renal Function and increases Lifespan in a Mouse Model of Alport Syndrome","volume":"33","author":"Widjaja","year":"2022","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0210","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1165\/rcmb.2020-0095MA","article-title":"Single-Nucleus RNA-Sequencing Profiling of Mouse Lung. Reduced Dissociation Bias and improved Rare Cell-Type Detection Compared with Single-Cell RNA Sequencing","volume":"63","author":"Koenitzer","year":"2020","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0215","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1182\/blood.V90.6.2148","article-title":"Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis","volume":"90","author":"Nandurkar","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.mucimm.2026.01.005_b0220","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1053\/j.gastro.2019.05.002","article-title":"Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis","volume":"157","author":"Widjaja","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mucimm.2026.01.005_b0225","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1042\/BCJ20220160","article-title":"Understanding interleukin 11 as a disease gene and therapeutic target","volume":"480","author":"Cook","year":"2023","journal-title":"Biochem J"},{"key":"10.1016\/j.mucimm.2026.01.005_b0230","doi-asserted-by":"crossref","first-page":"5579","DOI":"10.1158\/1078-0432.CCR-13-2492","article-title":"Molecular pathways: IL11 as a tumor-promoting cytokine-translational implications for cancers","volume":"20","author":"Ernst","year":"2014","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.mucimm.2026.01.005_b0235","doi-asserted-by":"crossref","first-page":"8530","DOI":"10.1038\/s41467-024-52810-8","article-title":"Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration","volume":"15","author":"Ng","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.mucimm.2026.01.005_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107144","article-title":"The role of epithelial cells in fibrosis: Mechanisms and treatment","volume":"202","author":"Luo","year":"2024","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.mucimm.2026.01.005_b0245","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/cei\/uxad108","article-title":"Interleukin-11 and its eminent role in tissue fibrosis: a possible therapeutic target","volume":"214","author":"O'Reilly","year":"2023","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0250","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nature24676","article-title":"IL-11 is a crucial determinant of cardiovascular fibrosis","volume":"552","author":"Schafer","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.mucimm.2026.01.005_b0255","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jse.2024.05.057","article-title":"Downregulation of interleukin 11 regulates the transforming growth factor-beta\/ERK1\/2 signaling pathway to inhibit articular capsule fibrosis and alleviate post-traumatic articular capsule contracture","volume":"34","author":"Zheng","year":"2025","journal-title":"J Shoulder Elbow Surg"},{"key":"10.1016\/j.mucimm.2026.01.005_b0260","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1086\/515686","article-title":"Recombinant human interleukin-11 in experimental Pseudomonas aeruginosa sepsis in immunocompromised animals","volume":"178","author":"Opal","year":"1998","journal-title":"J Infect Dis"},{"key":"10.1016\/j.mucimm.2026.01.005_b0265","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s40495-017-0114-1","article-title":"Type 2 cytokine responses: regulating immunity to helminth parasites and allergic inflammation","volume":"3","author":"Henry","year":"2017","journal-title":"Curr Pharmacol Rep"},{"key":"10.1016\/j.mucimm.2026.01.005_b0270","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.immuni.2017.11.015","article-title":"Recent advances in Type-2-Cell-Mediated Immunity: Insights from Helminth Infection","volume":"47","author":"Harris","year":"2017","journal-title":"Immunity"},{"key":"10.1016\/j.mucimm.2026.01.005_b0275","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.3389\/fimmu.2019.02507","article-title":"The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune responses","volume":"10","author":"Egholm","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2021.101531","article-title":"Lessons in type 2 immunity: Neutrophils in Helminth infections","volume":"53","author":"Ajendra","year":"2021","journal-title":"Semin Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0285","doi-asserted-by":"crossref","first-page":"5687","DOI":"10.1128\/IAI.72.10.5687-5692.2004","article-title":"Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness)","volume":"72","author":"Gillette-Ferguson","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.mucimm.2026.01.005_b0290","doi-asserted-by":"crossref","first-page":"464","DOI":"10.4049\/jimmunol.180.1.464","article-title":"Neutrophils clear bacteria associated with parasitic nematodes augmenting the development of an effective Th2-type response","volume":"180","author":"Pesce","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0295","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.micinf.2014.02.012","article-title":"Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis","volume":"16","author":"Bonne-Annee","year":"2014","journal-title":"Microbes Infect"},{"key":"10.1016\/j.mucimm.2026.01.005_b0300","doi-asserted-by":"crossref","first-page":"39648","DOI":"10.1038\/srep39648","article-title":"NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae","volume":"6","author":"Ajendra","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.mucimm.2026.01.005_b0305","doi-asserted-by":"crossref","DOI":"10.3390\/cells12151981","article-title":"The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease","volume":"12","author":"Tsioumpekou","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.mucimm.2026.01.005_b0310","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abg6497","article-title":"Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration","volume":"7","author":"Allanki","year":"2021","journal-title":"Sci Adv"},{"key":"10.1016\/j.mucimm.2026.01.005_b0315","article-title":"Eosinophil trafficking in allergen-mediated pulmonary inflammation relies on IL-13-driven CCL-11 and CCL-24 production by tissue fibroblasts and myeloid cells","volume":"2","author":"Gazzinelli-Guimaraes","year":"2023","journal-title":"J Allergy Clin Immunol Glob"},{"key":"10.1016\/j.mucimm.2026.01.005_b0320","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.4049\/jimmunol.1600829","article-title":"Allergic Sensitization Underlies Hyperreactive Antigen-specific CD4+ T Cell responses in coincident Filarial Infection","volume":"197","author":"Gazzinelli-Guimaraes","year":"2016","journal-title":"J Immunol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0325","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41587-023-01767-y","article-title":"Dictionary learning for integrative, multimodal and scalable single-cell analysis","volume":"42","author":"Hao","year":"2024","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.mucimm.2026.01.005_b0330","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","article-title":"Fast, sensitive and accurate integration of single-cell data with Harmony","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nat Methods"},{"key":"10.1016\/j.mucimm.2026.01.005_b0335","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.cell.2018.05.061","article-title":"Recovering Gene Interactions from Single-Cell Data using Data Diffusion","volume":"174","author":"van Dijk","year":"2018","journal-title":"Cell"}],"container-title":["Mucosal Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193302192600005X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193302192600005X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T07:22:26Z","timestamp":1782112946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193302192600005X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S193302192600005X"],"URL":"https:\/\/doi.org\/10.1016\/j.mucimm.2026.01.005","relation":{},"ISSN":["1933-0219"],"issn-type":[{"value":"1933-0219","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IL-11 acts as an alarmin-like pro-inflammatory mediator regulating mucosal responses during helminth infection","name":"articletitle","label":"Article Title"},{"value":"Mucosal Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mucimm.2026.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of Society for Mucosal Immunology.","name":"copyright","label":"Copyright"}]}}