{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:12:08Z","timestamp":1791288728974,"version":"4.3.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.mvr.2005.09.001","type":"journal-article","created":{"date-parts":[[2005,10,15]],"date-time":"2005-10-15T11:10:54Z","timestamp":1129374654000},"page":"121-128","source":"Crossref","is-referenced-by-count":23,"title":["Flow motion pattern differences in the forehead and forearm skin: Age-dependent alterations are not specific for Alzheimer's disease"],"prefix":"10.1016","volume":"70","author":[{"given":"Ferenc","family":"Bari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria","family":"T\u00f3th-Sz\u0171ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferenc","family":"Domoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1nos","family":"K\u00e1lm\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2005.09.001_bib1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3233\/THC-1999-72-301","article-title":"Higher-order spectral analysis in laser-Doppler flowmetry signal processing","volume":"7","author":"Alexopoulos","year":"1999","journal-title":"Technol. Health Care"},{"key":"10.1016\/j.mvr.2005.09.001_bib2","first-page":"H867","article-title":"Synchronous and baroceptor-sensitive oscillations in skin microcirculation: evidence for central autonomic control","volume":"273","author":"Bernardi","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2005.09.001_bib3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0008-6363(97)00017-5","article-title":"Reduction of 0.1 Hz microcirculatory fluctuations as evidence of sympathetic dysfunction in insulin-dependent diabetes","volume":"34","author":"Bernardi","year":"1997","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib4","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/mvre.1994.1039","article-title":"Effects of l-NMMA and indomethacin on arteriolar vasomotion in skeletal muscle microcirculation of conscious and anesthetized hamsters","volume":"48","author":"Bertuglia","year":"1994","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib5","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1001\/archneur.55.9.1179","article-title":"Alzheimer disease-related abnormalities of amyloid beta precursor protein isoforms in the platelet: the brain's delegate in the periphery?","volume":"55","author":"Bush","year":"1998","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.mvr.2005.09.001_bib6","doi-asserted-by":"crossref","first-page":"R121","DOI":"10.1007\/s004240000030","article-title":"Role of alpha-adrenoceptors in the cutaneous postocclusive reactive hyperaemia","volume":"440","author":"Cankar","year":"2000","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.mvr.2005.09.001_bib7","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1113\/jphysiol.1987.sp016651","article-title":"The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia","volume":"389","author":"Carlsson","year":"1987","journal-title":"J. Physiol."},{"key":"10.1016\/j.mvr.2005.09.001_bib8","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1006\/mvre.2000.2273","article-title":"Failure of laser Doppler signal to correlate with total flow in muscle: is this a question of vessel architecture?","volume":"60","author":"Clark","year":"2000","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib10","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-3940(03)00191-5","article-title":"Perineural capsaicin treatment attenuates reactive hyperaemia in the rat skin","volume":"341","author":"Domoki","year":"2003","journal-title":"Neurosci. Lett."},{"issue":"Suppl. 3","key":"10.1016\/j.mvr.2005.09.001_bib11","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1097\/00005344-198500073-00007","article-title":"Dynamics of skin microcirculation in humans","volume":"7","author":"Fagrell","year":"1985","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.mvr.2005.09.001_bib12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.atherosclerosis.2003.11.015","article-title":"Non-invasive assessment of microvascular endothelial function by laser Doppler flowmetry in patients with essential hypertension","volume":"173","author":"Farkas","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mvr.2005.09.001_bib13","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib14","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1001\/archneur.1975.00490510088009","article-title":"Cerebral blood flow in dementia","volume":"32","author":"Hachinski","year":"1975","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.mvr.2005.09.001_bib15","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1254\/jphs.93.405","article-title":"New methods to evaluate endothelial function: non-invasive method of evaluating endothelial function in humans","volume":"93","author":"Hashimoto","year":"2003","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.mvr.2005.09.001_bib16","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1113\/jphysiol.1993.sp019690","article-title":"Innervation of the cat lip by two groups of parasympathetic vasodilator fibres","volume":"465","author":"Izumi","year":"1993","journal-title":"J. Physiol."},{"key":"10.1016\/j.mvr.2005.09.001_bib17","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.CIR.91.5.1314","article-title":"Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo","volume":"91","author":"Joannides","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2005.09.001_bib18","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/gps.609","article-title":"Decreased cutaneous vasodilatation to isometric handgrip exercise in Alzheimer's disease","volume":"17","author":"Kalman","year":"2002","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.mvr.2005.09.001_bib19","first-page":"45","article-title":"Automated diameter measurement of vasomotion by cross-correlation","volume":"4","author":"Kaufman","year":"1985","journal-title":"Int. J. Microcirc. Clin. Exp."},{"key":"10.1016\/j.mvr.2005.09.001_bib20","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1152\/japplphysiol.00202.2003","article-title":"Invited review: aging and human temperature regulation","volume":"95","author":"Kenney","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2005.09.001_bib21","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0006-8993(96)00685-3","article-title":"Mechanisms underlying the vascular activity of beta-amyloid protein fragment (beta A(4)25\u201335) at the level of skin microvasculature","volume":"736","author":"Khalil","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib22","doi-asserted-by":"crossref","first-page":"467","DOI":"10.3233\/JAD-2002-4603","article-title":"Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein","volume":"4","author":"Khalil","year":"2002","journal-title":"J. Alzheimer's Dis."},{"key":"10.1016\/j.mvr.2005.09.001_bib23","first-page":"43","article-title":"The effect of oxygen supplementation on post-occlusive reactive hyperaemia in human forearm skin","volume":"10","author":"Khan","year":"1991","journal-title":"Int. J. Microcirc. Clin. Exp."},{"key":"10.1016\/j.mvr.2005.09.001_bib24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1136\/ard.59.1.48","article-title":"Impaired microvascular response to cholinergic stimuli in primary Sjogren's syndrome","volume":"59","author":"Kovacs","year":"2000","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mvr.2005.09.001_bib25","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0026-2862(03)00006-2","article-title":"Regulation of human cutaneous circulation evaluated by laser Doppler flowmetry, iontophoresis, and spectral analysis: importance of nitric oxide and prostaglandines","volume":"65","author":"Kvandal","year":"2003","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib26","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1006\/mvre.1995.1041","article-title":"Spontaneous flow waves detected by laser Doppler in human skin","volume":"50","author":"Lossius","year":"1995","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib27","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.mvr.2005.09.001_bib28","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0026-2862(88)90062-3","article-title":"Vasomotion patterns in skeletal muscle arterioles during changes in arterial pressure","volume":"35","author":"Meyer","year":"1988","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib29","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1046\/j.1365-2125.1999.00032.x","article-title":"Forearm reactive hyperaemia is not mediated by nitric oxide in healthy volunteers","volume":"48","author":"Nugent","year":"1999","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.mvr.2005.09.001_bib30","first-page":"197","article-title":"Reactive hyperaemia in the human forearm","volume":"14","author":"Patterson","year":"1955","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.mvr.2005.09.001_bib31","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3233\/THC-1999-72-311","article-title":"Dynamic characteristics of laser-Doppler flux data","volume":"7","author":"Popivanov","year":"1999","journal-title":"Technol. Health Care"},{"key":"10.1016\/j.mvr.2005.09.001_bib32","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0026-2862(91)90010-9","article-title":"The cutaneous microcirculation of the forearm in young and old subjects","volume":"41","author":"Richardson","year":"1991","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib33","doi-asserted-by":"crossref","unstructured":"Rossi, M., Maurizio, S., Carpi, A., in press. Skin blood flowmotion response to insulin iontophoresis in normal subjects. Microvascular Research, available online 1 July 2005.","DOI":"10.1016\/j.mvr.2005.05.001"},{"key":"10.1016\/j.mvr.2005.09.001_bib34","first-page":"91","article-title":"Rhythmical variations in human skin blood flow","volume":"2","author":"Salerud","year":"1983","journal-title":"Int. J. Microcirc. Clin. Exp."},{"key":"10.1016\/j.mvr.2005.09.001_bib35","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0165-1838(99)00029-6","article-title":"Effects of sympathetic nerve blockades on low-frequency oscillations of human earlobe skin blood flow","volume":"77","author":"Sasano","year":"1999","journal-title":"J. Auton. Nerv. Syst."},{"key":"10.1016\/j.mvr.2005.09.001_bib36","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1097\/00004872-200108000-00006","article-title":"The return of increased blood pressure after discontinuation of antihypertensive treatment is associated with an impaired post-ischemic skin blood flow response","volume":"19","author":"Sieg-Dobrescu","year":"2001","journal-title":"J. Hypertens."},{"key":"10.1016\/j.mvr.2005.09.001_bib37","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1006\/mvre.2001.2385","article-title":"Distinction between atropine-sensitive control of microvascular and cardiac oscillatory activity","volume":"63","author":"Silverman","year":"2002","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2005.09.001_bib38","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S1056-8727(01)00152-0","article-title":"Comparison of laser-Doppler flowmetry with biochemical indicators of endothelial dysfunction related to early microangiopathy in Type 1 diabetic patients","volume":"15","author":"Skrha","year":"2001","journal-title":"J. Diabetes Its Complicat."},{"key":"10.1016\/j.mvr.2005.09.001_bib39","doi-asserted-by":"crossref","first-page":"715","DOI":"10.2337\/diacare.19.7.715","article-title":"Impaired peripheral vasomotion in diabetes","volume":"19","author":"Stansberry","year":"1996","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mvr.2005.09.001_bib40","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1109\/10.790500","article-title":"Wavelet analysis of oscillations in the peripheral blood circulation measured by laser Doppler technique","volume":"46","author":"Stefanovska","year":"1999","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.mvr.2005.09.001_bib41","first-page":"193","article-title":"Isometric handgrip exercise-induced muscarinic vasodilation in the human skin microvasculature","volume":"85","author":"Torok","year":"1998","journal-title":"Acta Physiol. Hung."},{"key":"10.1016\/j.mvr.2005.09.001_bib42","first-page":"75","article-title":"Evidence of flowmotion induced changes in local tissue oxygenation","volume":"12","author":"Tsai","year":"1993","journal-title":"Int. J. Microcirc. Clin. Exp."},{"key":"10.1016\/j.mvr.2005.09.001_bib43","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/ageing\/21.4.237","article-title":"Analysis of the diminished skin perfusion in elderly people by laser Doppler flowmetry","volume":"21","author":"Weiss","year":"1992","journal-title":"Age Ageing"}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286205000701?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286205000701?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T09:04:34Z","timestamp":1586509474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286205000701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0026286205000701"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2005.09.001","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}