{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:11:41Z","timestamp":1781640701044,"version":"3.54.5"},"reference-count":148,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.mvr.2008.05.001","type":"journal-article","created":{"date-parts":[[2008,6,11]],"date-time":"2008-06-11T09:26:52Z","timestamp":1213176412000},"page":"114-123","source":"Crossref","is-referenced-by-count":14,"title":["Pathophysiological role of platelets and platelet system in acute pancreatitis"],"prefix":"10.1016","volume":"76","author":[{"given":"Dirk","family":"Uhlmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heike","family":"Lauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Serr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Witzigmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2008.05.001_bib1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1023\/A:1007074420772","article-title":"Inflammatory mediators and modulation of blood-brain barrier permeability","volume":"20","author":"Abbott","year":"2000","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib2","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.1182\/blood.V96.10.3322","article-title":"Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins","volume":"96","author":"Andre","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.mvr.2008.05.001_bib3","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1038\/sj.bjp.0704027","article-title":"Signal transduction pathways involved in kinin B(2) receptor-mediated vasodilation in the rat isolated perfused kidney","volume":"132","author":"Bagate","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib4","first-page":"1063","article-title":"Serotonin, histamine and platelets in vascular disease with special reference to peripheral vascular disease","volume":"25","author":"Barradas","year":"1992","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/sj.mn.7300054","article-title":"Vascular endothelial growth factor and microvascular permeability","volume":"6","author":"Bates","year":"1999","journal-title":"Microcirculation"},{"key":"10.1016\/j.mvr.2008.05.001_bib6","first-page":"G143","article-title":"ET-1 induced alterations of hepatic microcirculation: sinusoidal and extrasinusoidal sites of action","volume":"267","author":"Bauer","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib7","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1042\/bst0210330","article-title":"Pathological implications of nitric oxide, superoxide and peroxynitrite formation","volume":"21","author":"Beckman","year":"1993","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.mvr.2008.05.001_bib8","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/00007890-200103270-00012","article-title":"Impairment of microcirculation in the early reperfusion period predicts the degree of graft pancreatitis in clinical pancreas transplantation","volume":"71","author":"Benz","year":"2001","journal-title":"Transplantation"},{"issue":"Suppl 1","key":"10.1016\/j.mvr.2008.05.001_bib9","doi-asserted-by":"crossref","first-page":"S433","DOI":"10.1007\/s001470050515","article-title":"Impairment of pancreatic microcirculation in the early reperfusion period during simultaneous pancreas\u2013kidney transplantation","volume":"11","author":"Benz","year":"1998","journal-title":"Transpl. Int."},{"key":"10.1016\/j.mvr.2008.05.001_bib10","first-page":"G42","article-title":"Inhibition of bradykinin B2 receptor preserves microcirculation in experimental pancreatitis in rats","volume":"274","author":"Bloechle","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib11","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1165\/ajrcmb.18.1.2314","article-title":"Neutrophil\u2013platelet adhesion: relative roles of platelet P-selectin and neutrophil beta2 (DC18) integrins","volume":"18","author":"Brown","year":"1998","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.mvr.2008.05.001_bib12","first-page":"165","article-title":"Importance of brain-gut axis in the gastroprotection induced by gastric and remote preconditioning","volume":"55","author":"Brzozowski","year":"2004","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib13","first-page":"159","article-title":"Possible induction of intercellular adhesion molecule-1 (ICAM-1) expression on endothelial cells by platelet-activating factor (PAF)","volume":"5","author":"Chihara","year":"1992","journal-title":"J. Lipid Mediat."},{"key":"10.1016\/j.mvr.2008.05.001_bib14","doi-asserted-by":"crossref","first-page":"H274","DOI":"10.1152\/ajpheart.01031.2006","article-title":"Human recombinant erythropoietin protects the striated muscle microcirculation of the dorsal skinfold from postischemic injury in mice","volume":"293","author":"Contaldo","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib15","doi-asserted-by":"crossref","first-page":"G1027","DOI":"10.1152\/ajpgi.00457.2002","article-title":"Time-dependent platelet\u2013vessel wall interactions induced by intestinal ischemia\u2013reperfusion","volume":"284","author":"Cooper","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib16","doi-asserted-by":"crossref","first-page":"H1895","DOI":"10.1152\/ajpheart.01000.2003","article-title":"Leukocyte dependence of platelet adhesion in postcapillary venules","volume":"286","author":"Cooper","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib17","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1007\/BF01965409","article-title":"Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist","volume":"12","author":"de Clerck","year":"1982","journal-title":"Agents Actions"},{"key":"10.1016\/j.mvr.2008.05.001_bib18","first-page":"39","article-title":"Effect of ischemic preconditioning on pancreatic regeneration and pancreatic expression of vascular endothelial growth factor and platelet-derived growth factor-A in ischemia\/reperfusion-induced pancreatitis","volume":"57","author":"Dembinski","year":"2006","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib19","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1159\/000179177","article-title":"Does nitric oxide protect from microcirculatory disturbances in experimental acute pancreatitis in rats?","volume":"16","author":"Dobosz","year":"1996","journal-title":"Int. J. Microcirc. Clin. Exp."},{"key":"10.1016\/j.mvr.2008.05.001_bib20","first-page":"155","article-title":"Nitric oxide, heparin and procaine treatment in experimental ceruleine-induced acute pancreatitis in rats","volume":"47","author":"Dobosz","year":"1999","journal-title":"Arch. Immunol. Ther. Exp. (Warsz)"},{"key":"10.1016\/j.mvr.2008.05.001_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0046-8177(98)80005-1","article-title":"Epstein\u2013Barr virus-related posttransplantation lymphoproliferative disorder involving pancreas allografts: histological differential diagnosis from acute allograft rejection","volume":"29","author":"Drachenberg","year":"1998","journal-title":"Human Pathol."},{"key":"10.1016\/j.mvr.2008.05.001_bib22","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1097\/00007890-200106270-00014","article-title":"Pancreas transplantation: the histologic morphology of graft loss and clinical correlations","volume":"71","author":"Drachenberg","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.mvr.2008.05.001_bib23","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/MOH.0b013e3280dce51a","article-title":"Signaling and regulation of the platelet glycoprotein Ib\u2013IX\u2013V complex","volume":"14","author":"Du","year":"2007","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.mvr.2008.05.001_bib24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00134-001-1194-1","article-title":"Therapy of microcirculatory disorders in severe acute pancreatitis: what mediators should we block?","volume":"28","author":"Eibl","year":"2002","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.mvr.2008.05.001_bib25","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/gut.46.3.390","article-title":"Effect of endothelin and endothelin receptor blockade on capillary permeability in experimental pancreatitis","volume":"46","author":"Eibl","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.mvr.2008.05.001_bib26","first-page":"315","article-title":"Experimental acute pancreatitis induced by platelet activating factor in rabbits","volume":"134","author":"Emanuelli","year":"1989","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.mvr.2008.05.001_bib27","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1161\/01.RES.79.3.560","article-title":"Heterogeneity of expression of E- and P-selectins in vivo","volume":"79","author":"Eppihimer","year":"1996","journal-title":"Circ Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib28","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/j.1476-5381.1996.tb15547.x","article-title":"Bradykinin and changes in microvascular permeability in the hamster cheek pouch: role of nitric oxide","volume":"118","author":"Feletou","year":"1996","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib29","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1111\/j.1476-5381.1994.tb17070.x","article-title":"Characterization of receptors mediating vascular responses to endothelin-1 in the conscious rat","volume":"113","author":"Filep","year":"1994","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib30","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF00227892","article-title":"Paracrine functions of the coronary vascular endothelium","volume":"157","author":"Fleming","year":"1996","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.mvr.2008.05.001_bib31","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1093\/cvr\/28.11.1662","article-title":"Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects","volume":"28","author":"Flores","year":"1994","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib32","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S1091-255X(00)80072-4","article-title":"Therapy for microcirculatory disorders in severe acute pancreatitis: comparison of delayed therapy with ICAM-1 antibodies and a specific endothelin A receptor antagonist","volume":"4","author":"Foitzik","year":"2000","journal-title":"J. Gastrointest. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib33","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1067\/msy.2000.107104","article-title":"Endothelin receptor blockade in severe acute pancreatitis leads to systemic enhancement of microcirculation, stabilization of capillary permeability, and improved survival rates","volume":"128","author":"Foitzik","year":"2000","journal-title":"Surgery"},{"key":"10.1016\/j.mvr.2008.05.001_bib34","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1097\/00000658-199811000-00006","article-title":"Endothelin receptor blockade improves fluid sequestration, pancreatic capillary blood flow, and survival in severe experimental pancreatitis","volume":"228","author":"Foitzik","year":"1998","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib35","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S1091-255X(98)80078-4","article-title":"Endothelin-1 mediates the alcohol-induced reduction of pancreatic capillary blood flow","volume":"2","author":"Foitzik","year":"1998","journal-title":"J. Gastrointest. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib36","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1084\/jem.191.8.1413","article-title":"P-selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet\u2013endothelial interactions in vivo","volume":"191","author":"Frenette","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.mvr.2008.05.001_bib37","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/S0016-5085(99)70192-7","article-title":"The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury","volume":"116","author":"Frossard","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mvr.2008.05.001_bib38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1476-5381.1995.tb14911.x","article-title":"Cytochrome P450-dependent effects of bradykinin in the rat heart","volume":"114","author":"Fulton","year":"1995","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib39","first-page":"463","article-title":"Expression of platelet endothelial cell adhesion molecule-1 between pancreatic microcirculation and peripheral circulation in rats with acute edematous pancreatitis","volume":"2","author":"Gao","year":"2003","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"10.1016\/j.mvr.2008.05.001_bib40","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3748\/wjg.v11.i5.661","article-title":"Differences in platelet endothelial cell adhesion molecule-1 expression between peripheral circulation and pancreatic microcirculation in cerulein-induced acute edematous pancreatitis","volume":"11","author":"Gao","year":"2005","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.mvr.2008.05.001_bib41","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1046\/j.1365-2141.2003.04369.x","article-title":"Flow cytometry detection of serotonin content and release in resting and activated platelets","volume":"121","author":"Gobbi","year":"2003","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.mvr.2008.05.001_bib42","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00006676-200208000-00007","article-title":"Mechanisms of Chinese herb emodin and somatostatin analogs on pancreatic regeneration in acute pancreatitis in rats","volume":"25","author":"Gong","year":"2002","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib43","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1038\/sj.onc.1208513","article-title":"HIF-1alpha, STAT3, CBP\/p300 and Ref-1\/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas","volume":"24","author":"Gray","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.mvr.2008.05.001_bib44","first-page":"G1402","article-title":"Early NF-kappaB activation is associated with hormone-induced pancreatitis","volume":"275","author":"Gukovsky","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib45","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/01.mpa.0000194610.62723.18","article-title":"Ciclosporin aggravates tissue damage in ischemia reperfusion-induced acute pancreatitis","volume":"32","author":"Hackert","year":"2006","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib46","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1002\/bjs.4966","article-title":"Platelet function in acute experimental pancreatitis induced by ischaemia\u2013reperfusion","volume":"92","author":"Hackert","year":"2005","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib47","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1055\/s-0038-1648163","article-title":"MCI-9042, a new antiplatelet agent is a selective S2-serotonergic receptor antagonist","volume":"65","author":"Hara","year":"1991","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.mvr.2008.05.001_bib48","doi-asserted-by":"crossref","first-page":"G1194","DOI":"10.1152\/ajpgi.00221.2004","article-title":"Membrane-bound ICAM-1 is upregulated by trypsin and contributes to leukocyte migration in acute pancreatitis","volume":"287","author":"Hartwig","year":"2004","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib49","first-page":"G984","article-title":"Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents","volume":"264","author":"Hildebrand","year":"1993","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib50","first-page":"203","article-title":"Thromboxane A2 receptor antagonist prevents pancreatic microvascular leakage in rats with caerulein-induced acute pancreatitis","volume":"1","author":"Hirano","year":"1999","journal-title":"Int. J. Surg. Investig."},{"key":"10.1016\/j.mvr.2008.05.001_bib51","doi-asserted-by":"crossref","first-page":"S274","DOI":"10.1097\/00004872-198900076-00133","article-title":"Massive regional differences in the vascular effects of endothelin","volume":"7","author":"Hof","year":"1989","journal-title":"J. Hypertens., Suppl."},{"key":"10.1016\/j.mvr.2008.05.001_bib52","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/bjs.1800830213","article-title":"Bradykinin antagonists HOE-140 and CP-0597 diminish microcirculatory injury after ischaemia\u2013reperfusion of the pancreas in rats","volume":"83","author":"Hoffmann","year":"1996","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib53","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1182\/blood-2007-06-098392","article-title":"Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide\/cGMP signaling","volume":"111","author":"Isenberg","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.mvr.2008.05.001_bib54","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000018699","article-title":"Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis","volume":"16","author":"Johnson","year":"1999","journal-title":"Dig. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib55","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1136\/gut.48.1.62","article-title":"Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis","volume":"48","author":"Johnson","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.mvr.2008.05.001_bib56","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/00006676-199307000-00006","article-title":"Release of platelet-activating factor in acute experimental pancreatitis","volume":"8","author":"Kald","year":"1993","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib57","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1161\/01.RES.86.10.1031","article-title":"Immunoneutralization of glycoprotein Ibalpha attenuates endotoxin-induced interactions of platelets and leukocytes with rat venular endothelium in vivo","volume":"86","author":"Katayama","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib58","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1159\/000085278","article-title":"Pancreatic proteases in serum induce leukocyte\u2013endothelial adhesion and pancreatic microcirculatory failure","volume":"5","author":"Keck","year":"2005","journal-title":"Pancreatology"},{"key":"10.1016\/j.mvr.2008.05.001_bib59","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/00007890-200209150-00016","article-title":"Platelet adhesion mediated by fibrinogen\u2013intercellular adhesion molecule-1 binding induces tissue injury in the postischemic liver in vivo","volume":"74","author":"Khandoga","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.mvr.2008.05.001_bib60","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/00024382-200212000-00008","article-title":"P-selectin mediates platelet\u2013endothelial cell interactions and reperfusion injury in the mouse liver in vivo","volume":"18","author":"Khandoga","year":"2002","journal-title":"Shock"},{"key":"10.1016\/j.mvr.2008.05.001_bib61","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1002\/bjs.1800821039","article-title":"Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis","volume":"82","author":"Kingsnorth","year":"1995","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib62","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1007\/BF02087702","article-title":"Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas","volume":"39","author":"Klar","year":"1994","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.mvr.2008.05.001_bib63","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1055\/s-0038-1649935","article-title":"Shear-induced platelet aggregation in normal subjects and stroke patients","volume":"74","author":"Konstantopoulos","year":"1995","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.mvr.2008.05.001_bib64","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/01.CIR.98.9.873","article-title":"Venous levels of shear support neutrophil\u2013platelet adhesion and neutrophil aggregation in blood via P-selectin and beta2-integrin","volume":"98","author":"Konstantopoulos","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib65","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1136\/gut.33.9.1268","article-title":"Role of platelet activating factor in pathogenesis of acute pancreatitis in rats","volume":"33","author":"Konturek","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.mvr.2008.05.001_bib66","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1096\/fasebj.7.13.8405815","article-title":"Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells","volume":"7","author":"Kubes","year":"1993","journal-title":"FASEB J."},{"key":"10.1016\/j.mvr.2008.05.001_bib67","doi-asserted-by":"crossref","first-page":"4651","DOI":"10.1073\/pnas.88.11.4651","article-title":"Nitric oxide: an endogenous modulator of leukocyte adhesion","volume":"88","author":"Kubes","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mvr.2008.05.001_bib68","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0022-2143(96)90026-8","article-title":"Ischemic preconditioning of the liver in rats: implications of heat shock protein induction to increase tolerance of ischemia\u2013reperfusion injury","volume":"128","author":"Kume","year":"1996","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.mvr.2008.05.001_bib69","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/0016-5085(94)90238-0","article-title":"Effects of leukocyte and platelet depletion on ischemia\u2013reperfusion injury to dog pancreas","volume":"107","author":"Kuroda","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.mvr.2008.05.001_bib70","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1161\/01.RES.73.1.164","article-title":"Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage","volume":"73","author":"Kurose","year":"1993","journal-title":"Circ. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib71","doi-asserted-by":"crossref","first-page":"G1283","DOI":"10.1152\/ajpgi.00429.2006","article-title":"Effect of CP-96,345 on the expression of adhesion molecules in acute pancreatitis in mice","volume":"292","author":"Lau","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib72","first-page":"237","article-title":"Platelet aggregation, platelet serotonin and pancreatitis","volume":"5","author":"Lechin","year":"2004","journal-title":"Jop"},{"key":"10.1016\/j.mvr.2008.05.001_bib73","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1111\/j.1476-5381.1992.tb13397.x","article-title":"Phosphoramidon blocks big-endothelin-1 but not endothelin-1 enhancement of vascular permeability in the rat","volume":"107","author":"Lehoux","year":"1992","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib74","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/j.lfs.2005.09.053","article-title":"Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia\u2013reperfusion","volume":"78","author":"Liu","year":"2006","journal-title":"Life Sci"},{"key":"10.1016\/j.mvr.2008.05.001_bib75","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3109\/00365529509093277","article-title":"Effect of endothelin-1 on the development of hemorrhagic pancreatitis in rats","volume":"30","author":"Liu","year":"1995","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.mvr.2008.05.001_bib76","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.3748\/wjg.v11.i39.6208","article-title":"Microcirculation disturbance affects rats with acute severe pancreatitis following lung injury","volume":"11","author":"Liu","year":"2005","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.mvr.2008.05.001_bib77","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1161\/01.CIR.91.7.2080","article-title":"Effects of aspirin on platelet\u2013neutrophil interactions. Role of nitric oxide and endothelin-1","volume":"91","author":"Lopez-Farre","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib78","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1161\/01.CIR.88.3.1166","article-title":"Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart","volume":"88","author":"Lopez Farre","year":"1993","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib79","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1097\/00000658-200102000-00010","article-title":"Blocking pulmonary ICAM-1 expression ameliorates lung injury in established diet-induced pancreatitis","volume":"233","author":"Lundberg","year":"2001","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib80","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1161\/01.STR.14.4.475","article-title":"Recent progress in the role of platelets in occlusive vascular disease","volume":"14","author":"Marcus","year":"1983","journal-title":"Stroke"},{"key":"10.1016\/j.mvr.2008.05.001_bib81","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/00006676-200004000-00012","article-title":"Nitric oxide decreases endothelial activation by rat experimental severe pancreatitis-associated ascitic fluids","volume":"20","author":"Masamune","year":"2000","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib82","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1182\/blood.V92.2.507","article-title":"Platelet\u2013endothelial cell interactions during ischemia\/reperfusion: the role of P-selectin","volume":"92","author":"Massberg","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.mvr.2008.05.001_bib83","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1091-255X(99)80027-4","article-title":"Characterization and reduction of ischemia\/reperfusion injury after experimental pancreas transplantation","volume":"3","author":"Mayer","year":"1999","journal-title":"J. Gastrointest. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib84","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1002\/bjs.1800840912","article-title":"Prospective placebo-controlled randomized trial of lexipafant in predicted severe acute pancreatitis","volume":"84","author":"McKay","year":"1997","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib85","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/jsre.1993.1053","article-title":"Endothelin-stimulated human monocytes produce prostaglandin E2 but not leukotriene B4","volume":"54","author":"McMillen","year":"1993","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib86","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/BF02091517","article-title":"Ischemia\u2013reperfusion-induced pancreatic microvascular injury. An intravital fluorescence microscopic study in rats","volume":"41","author":"Menger","year":"1996","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.mvr.2008.05.001_bib87","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000077024","article-title":"Alterations of platelet function, number and indexes during acute pancreatitis","volume":"4","author":"Mimidis","year":"2004","journal-title":"Pancreatology"},{"key":"10.1016\/j.mvr.2008.05.001_bib88","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1056\/NEJM199312303292706","article-title":"The L-arginine\u2013nitric oxide pathway","volume":"329","author":"Moncada","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mvr.2008.05.001_bib89","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/01.CIR.74.5.1124","article-title":"Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium","volume":"74","author":"Murry","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib90","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1161\/01.CIR.95.10.2387","article-title":"Induction of cytokine expression in leukocytes by binding of thrombin-stimulated platelets","volume":"95","author":"Neumann","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib91","first-page":"2102","article-title":"In vivo evaluation of platelet\u2013endothelial interactions after transient retinal ischemia","volume":"42","author":"Nishijima","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mvr.2008.05.001_bib92","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1161\/01.RES.74.6.1133","article-title":"Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils","volume":"74","author":"Niu","year":"1994","journal-title":"Circ. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib93","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s11239-005-0343-8","article-title":"Losartan and simvastatin inhibit platelet activation in hypertensive patients","volume":"18","author":"Nomura","year":"2004","journal-title":"J. Thromb. Thrombolysis"},{"key":"10.1016\/j.mvr.2008.05.001_bib94","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1248\/bpb.30.313","article-title":"Tacrolimus (FK506) limits accumulation of granulocytes and platelets and protects against brain damage after transient focal cerebral ischemia in rat","volume":"30","author":"Noto","year":"2007","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.mvr.2008.05.001_bib95","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1097\/00006676-200310000-00020","article-title":"Endotoxin preconditioning in pancreatic ischemia\/reperfusion injury","volume":"27","author":"Obermaier","year":"2003","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib96","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1097\/mpa.0b013e318073d1b7","article-title":"Remote preconditioning reduces microcirculatory disorders in pancreatic ischemia\/reperfusion injury","volume":"35","author":"Oehmann","year":"2007","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib97","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.ejphar.2005.08.033","article-title":"Effects of R-102444 and its active metabolite R-96544, selective 5-HT2A receptor antagonists, on experimental acute and chronic pancreatitis: additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis","volume":"521","author":"Ogawa","year":"2005","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib98","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/00007890-199709270-00002","article-title":"Accumulation of platelets in rat syngeneic lung transplants: a potential factor responsible for preservation\u2013reperfusion injury","volume":"64","author":"Okada","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.mvr.2008.05.001_bib99","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/327524a0","article-title":"Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor","volume":"327","author":"Palmer","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.mvr.2008.05.001_bib100","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/jsre.1999.5610","article-title":"ET-1 induces pancreatitis-like microvascular deterioration and acinar cell injury","volume":"85","author":"Plusczyk","year":"1999","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib101","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/0022-4804(84)90195-1","article-title":"Platelet activation by human pancreatic fluid","volume":"37","author":"Prinz","year":"1984","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib102","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1161\/01.CIR.0000034048.38910.91","article-title":"Simvastatin inhibits inflammatory properties of Staphylococcus aureus alpha-toxin","volume":"106","author":"Pruefer","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2008.05.001_bib103","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00000658-200102000-00008","article-title":"Modulation of endogenous nitric oxide synthase in experimental acute pancreatitis: role of anti-ICAM-1 and oxygen free radical scavengers","volume":"233","author":"Rau","year":"2001","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib104","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/00006676-200107000-00012","article-title":"Anti-ICAM-1 antibody modulates late onset of acinar cell apoptosis and early necrosis in taurocholate-induced experimental acute pancreatitis","volume":"23","author":"Rau","year":"2001","journal-title":"Pancreas"},{"key":"10.1016\/j.mvr.2008.05.001_bib105","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1084\/jem.190.6.803","article-title":"The glycoprotein Ib\u2013IX\u2013V complex is a platelet counterreceptor for P-selectin","volume":"190","author":"Romo","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.mvr.2008.05.001_bib106","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/0006-291X(91)92093-Y","article-title":"Cytoprotective function of nitric oxide: inactivation of superoxide radicals produced by human leukocytes","volume":"181","author":"Rubanyi","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mvr.2008.05.001_bib107","doi-asserted-by":"crossref","first-page":"G123","DOI":"10.1152\/ajpgi.00303.2002","article-title":"Low venular shear rates promote leukocyte-dependent recruitment of adherent platelets","volume":"284","author":"Russell","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib108","doi-asserted-by":"crossref","first-page":"G1432","DOI":"10.1152\/ajpgi.2001.281.6.G1432","article-title":"Platelets modulate ischemia\/reperfusion-induced leukocyte recruitment in the mesenteric circulation","volume":"281","author":"Salter","year":"2001","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib109","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.4049\/jimmunol.157.7.3122","article-title":"Bradykinin stimulates alveolar macrophages to release neutrophil, monocyte, and eosinophil chemotactic activity","volume":"157","author":"Sato","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.mvr.2008.05.001_bib110","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1126\/science.1371193","article-title":"Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides","volume":"255","author":"Schmidt","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.mvr.2008.05.001_bib111","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0165-2478(01)00171-7","article-title":"Leukocyte\u2013endothelial adhesion is impaired in the cremaster muscle microcirculation of the copper-deficient rat","volume":"76","author":"Schuschke","year":"2001","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.mvr.2008.05.001_bib112","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1600-6143.2006.01589.x","article-title":"Sirolimus improves early microcirculation, but impairs regeneration after pancreatic ischemia\u2013reperfusion injury","volume":"7","author":"Serr","year":"2007","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.mvr.2008.05.001_bib113","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1111\/j.1600-6143.2007.01967.x","article-title":"Diannexin, a novel annexin V homodimer, protects rat liver transplants against cold ischemia\u2013reperfusion injury","volume":"7","author":"Shen","year":"2007","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.mvr.2008.05.001_bib114","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1159\/000087063","article-title":"Potential role of reactive oxygen species in pancreatitis-associated multiple organ dysfunction","volume":"5","author":"Shi","year":"2005","journal-title":"Pancreatology"},{"key":"10.1016\/j.mvr.2008.05.001_bib115","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/00365520410009555","article-title":"Role of nuclear factor-kappaB, reactive oxygen species and cellular signaling in the early phase of acute pancreatitis","volume":"40","author":"Shi","year":"2005","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.mvr.2008.05.001_bib116","first-page":"H152","article-title":"Concentration-dependent effects of bradykinin on leukocyte recruitment and venular hemodynamics in rat mesentery","volume":"277","author":"Shigematsu","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib117","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0304-3940(92)90806-I","article-title":"Histochemical demonstration of NADPH-diaphorase activity, a marker for nitric oxide synthase, in neurons of the rat pancreas","volume":"148","author":"Shimosegawa","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.mvr.2008.05.001_bib118","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1096\/fj.01-0199com","article-title":"Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure","volume":"15","author":"Singbartl","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.mvr.2008.05.001_bib119","first-page":"788","article-title":"Effect of the endothelin receptor antagonist bosentan on postischemic liver microcirculation","volume":"121","author":"Spiegel","year":"1996","journal-title":"Zentralbl. Chir."},{"key":"10.1016\/j.mvr.2008.05.001_bib120","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1093\/jn\/135.2.172","article-title":"The flavonoid phloretin suppresses stimulated expression of endothelial adhesion molecules and reduces activation of human platelets","volume":"135","author":"Stangl","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.mvr.2008.05.001_bib121","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0034-5687(01)00259-6","article-title":"Relationship between pancreatitis and lung diseases","volume":"128","author":"Steer","year":"2001","journal-title":"Respir. Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib122","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s002680020342","article-title":"Pancreas transplantation: the histologic morphology of graft loss and clinical correlations","volume":"25","author":"Sutherland","year":"2001","journal-title":"World J. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib123","first-page":"22","article-title":"The influence of erythropoietin (Epo) on intercellular adhesion molecule-1 (ICAM-1, CD54) and platelet\u2013endothelial cell adhesion molecule-1 (PECAM-1, CD31) expression on human umbilical vein endothelial cells (HUVEC) induced by tumor necrosis factor-alpha (TNF-alpha)","volume":"60","author":"Szczepanski","year":"2007","journal-title":"Wiad. Lek."},{"key":"10.1016\/j.mvr.2008.05.001_bib124","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/0024-3205(92)90231-D","article-title":"Effects of endothelin on microcirculation of the pancreas","volume":"51","author":"Takaori","year":"1992","journal-title":"Life. Sci."},{"key":"10.1016\/j.mvr.2008.05.001_bib125","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.surg.2005.07.006","article-title":"Attenuation of proinflammatory gene expression and microcirculatory disturbances by endothelin A receptor blockade after orthotopic liver transplantation in pigs","volume":"139","author":"Uhlmann","year":"2006","journal-title":"Surgery"},{"key":"10.1016\/j.mvr.2008.05.001_bib126","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00441-006-0319-9","article-title":"Pathophysiological role of platelets in acute experimental pancreatitis: influence of endothelin A receptor blockade","volume":"327","author":"Uhlmann","year":"2007","journal-title":"Cell. Tissue. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib127","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1055\/s-2001-19157","article-title":"Importance of microcirculatory disturbances in the pathogenesis of pancreatitis","volume":"126","author":"Uhlmann","year":"2001","journal-title":"Zentralbl. Chir."},{"key":"10.1016\/j.mvr.2008.05.001_bib128","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000008574","article-title":"Exogenous L-arginine protects liver microcirculation from ischemia reperfusion injury","volume":"30","author":"Uhlmann","year":"1998","journal-title":"Eur. Surg. Res."},{"key":"10.1016\/j.mvr.2008.05.001_bib129","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1097\/00007890-199904150-00004","article-title":"Attenuation of microvascular reperfusion injury in rat pancreas transplantation by L-arginine","volume":"67","author":"Vollmar","year":"1999","journal-title":"Transplantation"},{"key":"10.1016\/j.mvr.2008.05.001_bib130","doi-asserted-by":"crossref","first-page":"G791","DOI":"10.1152\/ajpgi.00407.2003","article-title":"Soluble complement receptor 1 preserves endothelial barrier function and microcirculation in postischemic pancreatitis in the rat","volume":"286","author":"von Dobschuetz","year":"2004","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib131","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/S0022-3565(24)34964-X","article-title":"Inhibition of neutrophil proteinases by recombinant serpin Lex032 reduces capillary no-reflow in ischemia\/reperfusion-induced acute pancreatitis","volume":"290","author":"von Dobschuetz","year":"1999","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.mvr.2008.05.001_bib132","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/01.tp.0000229434.92523.99","article-title":"Targeting vascular endothelial growth factor pathway offers new possibilities to counteract microvascular disturbances during ischemia\/reperfusion of the pancreas","volume":"82","author":"von Dobschuetz","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.mvr.2008.05.001_bib133","first-page":"303","article-title":"Influence of ischemic preconditioning on blood coagulation, fibrinolytic activity and pancreatic repair in the course of caerulein-induced acute pancreatitis in rats","volume":"58","author":"Warzecha","year":"2007","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib134","first-page":"791","article-title":"Immunohistochemical expression of FGF-2, PDGF-A, VEGF and TGF beta RII in the pancreas in the course of ischemia\/reperfusion-induced acute pancreatitis","volume":"55","author":"Warzecha","year":"2004","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib135","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1172\/JCI119742","article-title":"Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor","volume":"100","author":"Weber","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mvr.2008.05.001_bib136","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0039-6060(97)90178-1","article-title":"Differing roles of nitric oxide in the pathogenesis of acute edematous versus necrotizing pancreatitis","volume":"121","author":"Werner","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.mvr.2008.05.001_bib137","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1097\/00000658-199906000-00010","article-title":"Specific therapy for local and systemic complications of acute pancreatitis with monoclonal antibodies against ICAM-1","volume":"229","author":"Werner","year":"1999","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib138","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1172\/JCI118575","article-title":"Activated platelets signal chemokine synthesis by human monocytes","volume":"97","author":"Weyrich","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mvr.2008.05.001_bib139","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/01.sla.0000080830.77437.4f","article-title":"Endothelin(A) receptor blockade reduces ischemia\/reperfusion injury in pig pancreas transplantation","volume":"238","author":"Witzigmann","year":"2003","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2008.05.001_bib140","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0165-6147(89)90011-4","article-title":"Molecular biology and biochemistry of the endothelins","volume":"10","author":"Yanagisawa","year":"1989","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.mvr.2008.05.001_bib141","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/S0022-3565(24)37154-X","article-title":"Possible involvement of 5-HT2 receptor activation in aggravation of diet-induced acute pancreatitis in mice","volume":"283","author":"Yoshino","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.mvr.2008.05.001_bib142","first-page":"544","article-title":"The effects of prostaglandin E1 on the microperfusion of the pancreas during acute necrotizing pancreatitis in rats","volume":"49","author":"Yucel","year":"2002","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.mvr.2008.05.001_bib143","doi-asserted-by":"crossref","first-page":"G666","DOI":"10.1152\/ajpgi.2000.279.4.G666","article-title":"Cerulein upregulates ICAM-1 in pancreatic acinar cells, which mediates neutrophil adhesion to these cells","volume":"279","author":"Zaninovic","year":"2000","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.mvr.2008.05.001_bib144","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1172\/JCI29499","article-title":"Complete reversal of acid-induced acute lung injury by blocking of platelet\u2013neutrophil aggregation","volume":"116","author":"Zarbock","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mvr.2008.05.001_bib145","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/sj.bjp.0706862","article-title":"Pretreatment with simvastatin reduces myocardial no-reflow by opening mitochondrial K(ATP) channel","volume":"149","author":"Zhao","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mvr.2008.05.001_bib146","first-page":"195","article-title":"Structure and function of pancreatic microcirculation","volume":"18","author":"Zhou","year":"2001","journal-title":"Sheng Wu Yi Xue Gong Cheng Xue Za Zhi"},{"key":"10.1016\/j.mvr.2008.05.001_bib147","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3748\/wjg.v8.i3.406","article-title":"Influencing factors of pancreatic microcirculatory impairment in acute panceatitis","volume":"8","author":"Zhou","year":"2002","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.mvr.2008.05.001_bib148","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/ca.980080303","article-title":"Morphology of pancreatic microcirculation in the monkey: light and scanning electron microscopic study","volume":"8","author":"Zhou","year":"1995","journal-title":"Clin. Anat."}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286208000885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286208000885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T17:31:55Z","timestamp":1738258315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286208000885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":148,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0026286208000885"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2008.05.001","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}