{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:18:19Z","timestamp":1784225899073,"version":"3.55.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.mvr.2012.02.006","type":"journal-article","created":{"date-parts":[[2012,2,21]],"date-time":"2012-02-21T18:34:25Z","timestamp":1329849265000},"page":"105-108","source":"Crossref","is-referenced-by-count":40,"title":["PEDF-derived peptide inhibits corneal angiogenesis by suppressing VEGF expression"],"prefix":"10.1016","volume":"84","author":[{"given":"Takanori","family":"Matsui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayaka","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho-ichi","family":"Yamagishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2012.02.006_bb0005","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jdermsci.2009.12.010","article-title":"Topical application of anti-angiogenic peptides based on pigment epithelium-derived factor can improve psoriasis","volume":"57","author":"Abe","year":"2010","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.mvr.2012.02.006_bb0010","article-title":"The association between corneal neovascularization and visual acuity: a systematic review","author":"Bachmann","year":"2011","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.mvr.2012.02.006_bb0015","doi-asserted-by":"crossref","first-page":"149","DOI":"10.2174\/138945011794182746","article-title":"Clinical evidence of intravitreal triamcinolone acetonide in the management of age-related macular degeneration","volume":"12","author":"Becerra","year":"2011","journal-title":"Curr. Drug Targets."},{"key":"10.1016\/j.mvr.2012.02.006_bb0020","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/bjo.2011.204701","article-title":"Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable","volume":"96","author":"Cursiefen","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.mvr.2012.02.006_bb0025","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/02713680802245772","article-title":"Inhibitory effect of oral doxycycline on neovascularization in a rat corneal alkali burn model of angiogenesis","volume":"33","author":"Dan","year":"2008","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.mvr.2012.02.006_bb0030","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.285.5425.245","article-title":"Pigment epithelium-derived factor: A potent inhibitor of angiogenesis","volume":"285","author":"Dawson","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.mvr.2012.02.006_bb0035","first-page":"821","article-title":"Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth","volume":"43","author":"Duh","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mvr.2012.02.006_bb0040","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1002\/jor.20434","article-title":"PEDF-derived synthetic peptides exhibit antitumor activity in an orthotopic model of human osteosarcoma","volume":"25","author":"Ek","year":"2007","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.mvr.2012.02.006_bb0045","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1097\/ICO.0b013e3181cc7987","article-title":"Inhibition of chemical cautery-induced corneal neovascularization by topical pigment epithelium-derived factor eyedrops","volume":"29","author":"Jin","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.mvr.2012.02.006_bb0050","doi-asserted-by":"crossref","first-page":"302","DOI":"10.2174\/156652410791065255","article-title":"Structure-function relationships of PEDF","volume":"10","author":"Kawaguchi","year":"2010","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.mvr.2012.02.006_bb0055","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1167\/iovs.10-6167","article-title":"Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model","volume":"52","author":"Kubota","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mvr.2012.02.006_bb0060","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/01.ico.0000220768.11778.60","article-title":"Prevention of corneal neovascularization: evaluation of various commercially available compounds in an experimental rat model","volume":"25","author":"Riazi-Esfahani","year":"2006","journal-title":"Cornea"},{"key":"10.1016\/j.mvr.2012.02.006_bb0065","first-page":"2105","article-title":"The effect of total-body irradiation on corneal neovascularization in the Fischer 344 rat after chemical cauterization","volume":"32","author":"Scroggs","year":"1991","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mvr.2012.02.006_bb0070","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.2337\/diabetes.50.12.2641","article-title":"Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease","volume":"50","author":"Spranger","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.mvr.2012.02.006_bb0080","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/nrn1176","article-title":"PEDF: a multifaceted neurotrophic factor","volume":"4","author":"Tombran-Tink","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.mvr.2012.02.006_bb0075","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0014-4835(91)90248-D","article-title":"PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity","volume":"53","author":"Tombran-Tink","year":"1991","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.mvr.2012.02.006_bb0095","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0006-291X(02)00940-3","article-title":"Pigment epithelium-derived factor protects cultured retinal pericytes from advanced glycation end product-induced injury through its antioxidative properties","volume":"296","author":"Yamagishi","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mvr.2012.02.006_bb0105","doi-asserted-by":"crossref","first-page":"20213","DOI":"10.1074\/jbc.M602110200","article-title":"Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression","volume":"281","author":"Yamagishi","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mvr.2012.02.006_bb0100","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1055\/s-2007-970425","article-title":"Pigment epithelium-derived factor (PEDF) blocks advanced glycation end product (AGE)-induced angiogenesis in vitro","volume":"39","author":"Yamagishi","year":"2007","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.mvr.2012.02.006_bb0085","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2174\/138945008786786154","article-title":"Pigment epithelium-derived factor (PEDF): its potential therapeutic implication in diabetic vascular complications","volume":"9","author":"Yamagishi","year":"2008","journal-title":"Curr. Drug Targets."},{"key":"10.1016\/j.mvr.2012.02.006_bb0090","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.2174\/138161209787581940","article-title":"Atheroprotective properties of pigment epithelium-derived factor (PEDF) in cardiometabolic disorders","volume":"15","author":"Yamagishi","year":"2009","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.mvr.2012.02.006_bb0110","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1136\/bjo.2006.110890","article-title":"Positive association of pigment epithelium-derived factor with total antioxidant capacity in the vitreous fluid of patients with proliferative diabetic retinopathy","volume":"91","author":"Yokoi","year":"2007","journal-title":"Br. J. Ophthalmol."}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286212000489?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286212000489?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T10:53:21Z","timestamp":1656068001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286212000489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0026286212000489"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2012.02.006","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}