{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T07:07:40Z","timestamp":1777100860690,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.mvr.2016.03.007","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T02:28:57Z","timestamp":1458354537000},"page":"39-43","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Serum uric acid as a marker of microvascular damage in systemic sclerosis patients"],"prefix":"10.1016","volume":"106","author":[{"given":"Antonietta","family":"Gigante","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biagio","family":"Barbano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Barilaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Quarta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Ludovica","family":"Gasperini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Di Mario","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Romaniello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Amoroso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Cianci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Rosato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2016.03.007_bb0005","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1164\/ajrccm.154.1.8680691","article-title":"ATS recommendations for DLCO","volume":"154","author":"Abboud","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.mvr.2016.03.007_bb0010","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1053\/rmed.2003.1440","article-title":"Hyperuricemia as a prognostic factor in pulmonary arterial hypertension","volume":"97","author":"Bendayan","year":"2003","journal-title":"Respir. Med."},{"key":"10.1016\/j.mvr.2016.03.007_bb0015","first-page":"1281","article-title":"Inter- and intraobserver variability of the total thickness score (modified Rodnan TSS) in systemic sclerosis","volume":"22","author":"Clements","year":"1995","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0020","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1136\/annrheumdis-2013-203301","article-title":"Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study","volume":"73","author":"Coghlan","year":"2013","journal-title":"Ann. Rheum. Dis."},{"issue":"Suppl. 4","key":"10.1016\/j.mvr.2016.03.007_bb0025","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/rheumatology\/kel310","article-title":"Nailfold capillaroscopy is useful for the diagnosis and follow-up of autoimmune rheumatic diseases. A future tool for the analysis of microvascular heart involvement?","volume":"45","author":"Cutolo","year":"2006","journal-title":"Rheumatology"},{"key":"10.1016\/j.mvr.2016.03.007_bb0030","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00296-010-1557-4","article-title":"Significance of serum uric acid in pulmonary hypertension due to systemic sclerosis: a pilot study","volume":"31","author":"Dimitroulas","year":"2011","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.mvr.2016.03.007_bb0035","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1093\/rheumatology\/kes049","article-title":"Evaluation of chronic kidney disease epidemiology collaboration equation to estimate glomerular filtration rate in scleroderma patients","volume":"51","author":"Gigante","year":"2012","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.mvr.2016.03.007_bb0040","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.ijcard.2014.08.122","article-title":"Autonomic dysfunction in patients with systemic sclerosis: correlation with intrarenal arterial stiffness","volume":"177","author":"Gigante","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0045","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ijcard.2015.03.089","article-title":"Correlation between intrarenal arterial stiffness and exercise tolerance in systemic sclerosis patients without renal and cardiopulmonary impairment: the role of the microvascular damage","volume":"185","author":"Gigante","year":"2015","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0050","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1743-7075-1-10","article-title":"Uric acid: a new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: the urate redox shuttle","volume":"1","author":"Hayden","year":"2004","journal-title":"Nutr. Metab. (Lond.)"},{"key":"10.1016\/j.mvr.2016.03.007_bb0055","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1093\/ndt\/gft029","article-title":"Uric acid and chronic kidney disease: which is chasing which?","volume":"28","author":"Johnson","year":"2013","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.mvr.2016.03.007_bb0065","first-page":"202","article-title":"Scleroderma (systemic sclerosis): classification, subsets and pathogenesis","volume":"15","author":"LeRoy","year":"1998","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0070","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration): a new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.mvr.2016.03.007_bb0075","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1002\/art.37988","article-title":"Systemic sclerosis (scleroderma, SSc) is a vascular disease","volume":"65","author":"Matucci-Cerinic","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mvr.2016.03.007_bb0080","first-page":"2159","article-title":"A disease severity scale for systemic sclerosis: development and testing","volume":"26","author":"Medsger","year":"1999","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0085","doi-asserted-by":"crossref","first-page":"817","DOI":"10.7326\/0003-4819-93-6-817","article-title":"Serum uric acid in essential hypertension: an indicator of renal vascular involvement","volume":"93","author":"Messerli","year":"1980","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.mvr.2016.03.007_bb0090","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/rheumatology\/keh067","article-title":"Echocardiography and pulmonary function as screening tests for pulmonary arterial hypertension in systemic sclerosis","volume":"43","author":"Mukerjee","year":"2004","journal-title":"Rheumatology"},{"key":"10.1016\/j.mvr.2016.03.007_bb0095","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1536\/ihj.48.523","article-title":"Serum uric acid as a prognostic predictor in pulmonary arterial hypertension with connective tissue disease","volume":"48","author":"Njaman","year":"2007","journal-title":"Int. Heart J."},{"key":"10.1016\/j.mvr.2016.03.007_bb0100","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1148\/radiol.2523080351","article-title":"Renal resistive index and long-term outcome in chronic nephropathies","volume":"252","author":"Parolini","year":"2009","journal-title":"Radiology"},{"key":"10.1016\/j.mvr.2016.03.007_bb0105","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.semarthrit.2011.11.005","article-title":"Intrarenal hemodynamic parameters correlate with glomerular filtration rate and digital microvascular damage in patients with systemic sclerosis","volume":"41","author":"Rosato","year":"2012","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.mvr.2016.03.007_bb0110","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3109\/03009742.2012.723748","article-title":"Doppler indices of intrarenal arterial stiffness are useful in monitoring scleroderma renal crisis","volume":"42","author":"Rosato","year":"2013","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0115","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1523-1755.2005.00074.x","article-title":"Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats","volume":"67","author":"Sanchez-Lozada","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.mvr.2016.03.007_bb0120","first-page":"1134","article-title":"Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia","volume":"295","author":"Sanchez-Lozada","year":"2008","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.mvr.2016.03.007_bb0125","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1097\/BOR.0b013e3283588dcf","article-title":"Renal disease in scleroderma: an update on evaluation, risk stratification, pathogenesis and management","volume":"24","author":"Shanmugam","year":"2012","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.mvr.2016.03.007_bb0130","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1161\/HYPERTENSIONAHA.111.00612","article-title":"Diabetes mellitus and vascular disease","volume":"61","author":"Sowers","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.mvr.2016.03.007_bb0135","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000381317","article-title":"A biomarker of renal hemodynamic impairment","volume":"5","author":"Susic","year":"2015","journal-title":"Cardiorenal Med."},{"key":"10.1016\/j.mvr.2016.03.007_bb0140","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1136\/ard.60.6.592","article-title":"European multicentre study to define disease activity criteria for systemic sclerosis. II. Identification of disease activity variables and development of preliminary activity indexes","volume":"60","author":"Valentini","year":"2001","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mvr.2016.03.007_bb0145","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1002\/art.38098","article-title":"Classification criteria for systemic sclerosis: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"65","author":"van den Hoogen","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mvr.2016.03.007_bb0150","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/sj.ki.5002374","article-title":"Age- and gender specific reference values of estimated GFR in Caucasians: the Nijmegen Biomedical Study","volume":"72","author":"Wetzels","year":"2007","journal-title":"Kidney Int."}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286216300218?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286216300218?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T19:00:31Z","timestamp":1567710031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286216300218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":29,"alternative-id":["S0026286216300218"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2016.03.007","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum uric acid as a marker of microvascular damage in systemic sclerosis patients","name":"articletitle","label":"Article Title"},{"value":"Microvascular Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mvr.2016.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}