{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:46:04Z","timestamp":1789181164771,"version":"build-2803163510"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T00:00:00Z","timestamp":1524441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["09342\/Z\/10\/Z"],"award-info":[{"award-number":["09342\/Z\/10\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.mvr.2018.03.016","type":"journal-article","created":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T18:33:52Z","timestamp":1522348432000},"page":"173-177","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Automated structure and flow measurement \u2014 a promising tool in nailfold capillaroscopy"],"prefix":"10.1016","volume":"118","author":[{"given":"Michael","family":"Berks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6245-2721","authenticated-orcid":false,"given":"Graham","family":"Dinsdale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonia","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Manning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7867-9533","authenticated-orcid":false,"given":"Chris","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane L.","family":"Herrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2018.03.016_bb0005","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1136\/ard.2010.136929","article-title":"Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group","volume":"70","author":"Avouac","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mvr.2018.03.016_bb0010","series-title":"Medical Image Computing and Computer-Assisted Intervention MICCAI 2014. LNCS","first-page":"658","article-title":"An automated system for detecting and measuring nailfold capillaries","volume":"Vol. 8673","author":"Berks","year":"2014"},{"key":"10.1016\/j.mvr.2018.03.016_bb0015","series-title":"Medical Image Computing and Computer-Assisted Intervention\u2014MICCAI 2016. MICCAI 2016. Lecture Notes in Computer Science","article-title":"Improved diagnosis of systemic sclerosis using nailfold capillary flow","volume":"Vol. 9902","author":"Berks","year":"2016"},{"key":"10.1016\/j.mvr.2018.03.016_bb0020","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/rheumatology\/35.11.1127","article-title":"Increased nailfold capillary dimensions in primary Raynaud's phenomenon and systemic sclerosis","volume":"35","author":"Bukhari","year":"1996","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.mvr.2018.03.016_bb0025","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3899\/jrheum.120416","article-title":"Longterm effects of endothelin receptor antagonism on microvascular damage evaluated by nailfold capillaroscopic analysis in systemic sclerosis","volume":"40","author":"Cutolo","year":"2013","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mvr.2018.03.016_bb0030","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1007\/s10067-012-2074-5","article-title":"Bosentan fosters de-remodelling in systemic sclerosis","volume":"31","author":"Guiducci","year":"2012","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.mvr.2018.03.016_bb0035","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1549-8719.2011.00125.x","article-title":"Microvascular reactivity in response to smoking and oral antioxidants in humans","volume":"19","author":"Henriksson","year":"2011","journal-title":"Microcirculation"},{"key":"10.1016\/j.mvr.2018.03.016_bb0040","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1002\/art.27543","article-title":"Clinical implications from capillaroscopic analysis in patients with Raynaud's phenomenon and systemic sclerosis","volume":"62","author":"Herrick","year":"2010","journal-title":"Arthritis Rheum."},{"issue":"12","key":"10.1016\/j.mvr.2018.03.016_bb0045","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1002\/art.24038","article-title":"Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis","volume":"58","author":"Koenig","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mvr.2018.03.016_bb0050","first-page":"485","article-title":"Raynaud's phenomenon: a proposal for classification","volume":"10","author":"LeRoy","year":"1992","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.mvr.2018.03.016_bb0055","first-page":"1573","article-title":"Criteria for the classification of early systemic sclerosis","volume":"28","author":"LeRoy","year":"2001","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.mvr.2018.03.016_bb0060","series-title":"Directional Statistics","author":"Mardia","year":"2000"},{"key":"10.1016\/j.mvr.2018.03.016_bb0065","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/art.1780160506","article-title":"Patterns of finger capillary abnormalities in connective tissue disease by \u2018widefield\u2019 microscopy","volume":"16","author":"Maricq","year":"1973","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.mvr.2018.03.016_bb0070","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1177\/000331979804901104","article-title":"Effect of moxonidine and cilazapril on microcirculationn as assessed by finger nailfold capillaroscopy in mild-to-moderate hypertension","volume":"49","author":"Martina","year":"1998","journal-title":"Angiology"},{"key":"10.1016\/j.mvr.2018.03.016_bb0075","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1136\/ard.2008.106302","article-title":"The challenge of early systemic sclerosis for the EULAR Scleroderma Trial and Research Group (EUSTAR) community: it is time to cut the Gordian knot and develop a prevention or rescue strategy","volume":"68","author":"Matucci-Cerinic","year":"2009","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.mvr.2018.03.016_bb0080","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jaut.2014.01.020","article-title":"International consensus criteria for the diagnosis of Raynaud's phenomenon","volume":"48\u201349","author":"Maverakis","year":"2014","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.mvr.2018.03.016_bb0085","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/rheumatology\/kel383","article-title":"Assessment of digital vascular structure and function in response to bosentan in patients with systemic sclerosis-related Raynaud's phenomenon","volume":"46","author":"Moore","year":"2007","journal-title":"Rheumatology"},{"key":"10.1016\/j.mvr.2018.03.016_bb0090","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/rheumatology\/kep066","article-title":"Reduced red blood cell velocity in nail-fold capillaries as a sensitive and specific indicator of microcirculation injury in systemic sclerosis","volume":"48","author":"Mugii","year":"2009","journal-title":"Rheumatology"},{"key":"10.1016\/j.mvr.2018.03.016_bb0095","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/j.1549-8719.2011.00104.x","article-title":"Preliminary clinical evaluation of semi-automated nailfold capillaroscopy in the assessment of patients with Raynaud's phenomenon","volume":"18","author":"Murray","year":"2011","journal-title":"Microcirculation"},{"key":"10.1016\/j.mvr.2018.03.016_bb0100","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.mvr.2010.10.006","article-title":"Hemodynamic analysis of capillary in finger nail-fold using computational fluid dynamics and image estimation","volume":"81","author":"Shih","year":"2011","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.mvr.2018.03.016_bb0105","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/micc.12281","article-title":"Nailfold capillaroscopy and clinical applications in systemic sclerosis","volume":"23","author":"Smith","year":"2016","journal-title":"Microcirculation"},{"key":"10.1016\/j.mvr.2018.03.016_bb0110","first-page":"2636","article-title":"Simulating nailfold capillaroscopy sequences to evaluate algorithms for blood flow estimation","author":"Tresadern","year":"2013","journal-title":"Conf. Proc. IEEE Eng. Med. Biol. Soc."},{"issue":"72","key":"10.1016\/j.mvr.2018.03.016_bb0115","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1136\/annrheumdis-2013-204424","article-title":"Classification criteria for systemic sclerosis","volume":"2013","author":"Van den Hoogen","year":"2013","journal-title":"Ann. Rheum. Dis."}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286217302662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286217302662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T18:22:51Z","timestamp":1534962171000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286217302662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":23,"alternative-id":["S0026286217302662"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2018.03.016","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Automated structure and flow measurement \u2014 a promising tool in nailfold capillaroscopy","name":"articletitle","label":"Article Title"},{"value":"Microvascular Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mvr.2018.03.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}