{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:42:07Z","timestamp":1790116927659,"version":"4.0.1"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:00:00Z","timestamp":1703116800000},"content-version":"am","delay-in-days":295,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.mvr.2022.104469","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T20:09:26Z","timestamp":1671566966000},"page":"104469","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Moderate dose of dietary nitrate improves skeletal muscle microvascular function in patients with peripheral artery disease"],"prefix":"10.1016","volume":"146","author":[{"given":"Elizabeth J.","family":"Pekas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody P.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2022.104469_bb0005","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.niox.2009.01.002","article-title":"Plasma nitrite response and arterial reactivity differentiate vascular health and performance","volume":"20","author":"Allen","year":"2009","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.mvr.2022.104469_bb0010","first-page":"365","article-title":"Lisinopril: a new angiotensin-converting enzyme inhibitor","volume":"22","author":"Armayor","year":"1988","journal-title":"Drug Intell. Clin. Pharm."},{"key":"10.1016\/j.mvr.2022.104469_bb0015","doi-asserted-by":"crossref","first-page":"375","DOI":"10.5114\/aoms.2012.28568","article-title":"Peripheral arterial disease of the lower extremities","volume":"8","author":"Aronow","year":"2012","journal-title":"Arch. Med. Sci."},{"key":"10.1016\/j.mvr.2022.104469_bb0020","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/jhh.2016.34","article-title":"Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study","volume":"30","author":"Asgary","year":"2016","journal-title":"J. Hum. Hypertens."},{"key":"10.1016\/j.mvr.2022.104469_bb0025","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1123\/ijsnem.2021-0054","article-title":"Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease","volume":"31","author":"van der Avoort","year":"2021","journal-title":"Int. J. Sport Nutr. Exerc. Metab."},{"issue":"126","key":"10.1016\/j.mvr.2022.104469_bb0030","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1152\/japplphysiol.00166.2018","article-title":"Understanding near infrared spectroscopy and its application to skeletal muscle research","volume":"2019","author":"Barstow","year":"2019","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0035","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1080\/10739680591003413","article-title":"Arteriolization of capillaries and FGF-2 upregulation in skeletal muscles of patients with chronic peripheral arterial disease","volume":"12","author":"Baum","year":"2005","journal-title":"Microcirculation"},{"key":"10.1016\/j.mvr.2022.104469_bb0040","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1161\/CIRCULATIONAHA.119.040672","article-title":"Microvascular disease, peripheral artery disease, and amputation","volume":"140","author":"Beckman","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2022.104469_bb0045","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.niox.2018.08.007","article-title":"Inorganic nitrate supplementation enhances functional capacity and lower-limb microvascular reactivity in patients with peripheral artery disease","volume":"80","author":"Bock","year":"2018","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.mvr.2022.104469_bb0050","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/676235","article-title":"Effects of nitrate supplementation on cardiovascular and autonomic reactivity in African-American females","volume":"2014","author":"Bond","year":"2014","journal-title":"ISRN Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0055","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3389\/fphys.2012.00284","article-title":"Sympathetic regulation of vascular function in health and disease","volume":"3","author":"Bruno","year":"2012","journal-title":"Front. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0060","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jesf.2020.12.001","article-title":"Beetroot juice intake with different amounts of nitrate does not change aerobic exercise-mediated responses in heart rate variability in hypertensive postmenopausal women: a randomized, crossover and double-blind study","volume":"19","author":"Carrijo","year":"2021","journal-title":"J. Exerc. Sci. Fit."},{"key":"10.1016\/j.mvr.2022.104469_bb0065","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.3390\/nu7042801","article-title":"The potential benefits of red beetroot supplementation in health and disease","volume":"7","author":"Clifford","year":"2015","journal-title":"Nutrients"},{"key":"10.1016\/j.mvr.2022.104469_bb0070","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1139\/apnm-2017-0238","article-title":"Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise","volume":"42","author":"Clifford","year":"2017","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"10.1016\/j.mvr.2022.104469_bb0075","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0741-5214(03)01032-2","article-title":"Tissue (muscle) oxygen saturation (StO2): a new measure of symptomatic lower-extremity arterial disease","volume":"38","author":"Comerota","year":"2003","journal-title":"J. Vasc. Surg."},{"issue":"1086\u20131094","key":"10.1016\/j.mvr.2022.104469_bb0080","article-title":"Limb perfusion during exercise assessed by contrast ultrasound varies according to symptom severity in patients with peripheral artery disease","volume":"32","author":"Davidson","year":"2019","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.mvr.2022.104469_bb0085","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s40256-017-0221-8","article-title":"The real role of beta-blockers in daily cardiovascular therapy","volume":"17","author":"Dezsi","year":"2017","journal-title":"Am. J. Cardiovasc. Drugs"},{"key":"10.1016\/j.mvr.2022.104469_bb0090","first-page":"826","article-title":"The health-related quality of life of people with peripheral arterial disease in the community: the Edinburgh Artery Study","volume":"54","author":"Dumville","year":"2004","journal-title":"Br. J. Gen. Pract."},{"key":"10.1016\/j.mvr.2022.104469_bb0095","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1001\/archinte.1970.00310040140020","article-title":"Autonomic control of the peripheral vascular system","volume":"125","author":"Edis","year":"1970","journal-title":"Arch. Intern. Med."},{"issue":"829\u2013837","key":"10.1016\/j.mvr.2022.104469_bb0100","article-title":"Nitric oxide synthases: regulation and function","volume":"33","author":"Forstermann","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.mvr.2022.104469_bb0105","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/j.jvs.2019.04.493","article-title":"A low-cost, wireless near-infrared spectroscopy device detects the presence of lower extremity atherosclerosis as measured by computed tomographic angiography and characterizes walking impairment in peripheral artery disease","volume":"71","author":"Fuglestad","year":"2020","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.mvr.2022.104469_bb0110","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/0003319718790876","article-title":"Greater exercise pressor response is associated with impaired claudication outcomes in symptomatic peripheral artery disease","volume":"70","author":"Gardner","year":"2019","journal-title":"Angiology"},{"key":"10.1016\/j.mvr.2022.104469_bb0115","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1177\/0003319719838399","article-title":"Vascular inflammation, calf muscle oxygen saturation, and blood glucose are associated with exercise pressor response in symptomatic peripheral artery disease","volume":"70","author":"Gardner","year":"2019","journal-title":"Angiology"},{"key":"10.1016\/j.mvr.2022.104469_bb0120","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.jvs.2019.09.057","article-title":"Association between calf muscle oxygen saturation with ambulatory function and quality of life in symptomatic patients with peripheral artery disease","volume":"72","author":"Gardner","year":"2020","journal-title":"J. Vasc. Surg."},{"key":"10.1016\/j.mvr.2022.104469_bb0125","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.niox.2008.08.003","article-title":"The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash","volume":"19","author":"Govoni","year":"2008","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.mvr.2022.104469_bb0130","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1161\/CIRCRESAHA.115.305364","article-title":"The human microcirculation: regulation of flow and beyond","volume":"118","author":"Gutterman","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.mvr.2022.104469_bb0135","first-page":"919","article-title":"The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure","volume":"132","author":"Guyatt","year":"1985","journal-title":"Can. Med. Assoc. J."},{"key":"10.1016\/j.mvr.2022.104469_bb0140","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1055\/s-0034-1393976","article-title":"Overview of classification systems in peripheral artery disease","volume":"31","author":"Hardman","year":"2014","journal-title":"Semin. Intervent. Radiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0145","doi-asserted-by":"crossref","first-page":"H468","DOI":"10.1152\/ajpheart.00354.2020","article-title":"Impacts of prolonged sitting with mild hypercapnia on vascular and autonomic function in healthy recreationally active adults","volume":"319","author":"Headid","year":"2020","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0150","first-page":"9","article-title":"The nitric oxide system in peripheral artery disease: connection with oxidative stress and biopterins","author":"Ismaeel","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.mvr.2022.104469_bb0155","first-page":"11","article-title":"The effects of beetroot juice on blood pressure, microvascular function and large-vessel endothelial function: a randomized, double-blind, placebo-controlled pilot study in healthy older adults","author":"Jones","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.mvr.2022.104469_bb0160","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1161\/HYPERTENSIONAHA.114.04675","article-title":"Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study","volume":"65","author":"Kapil","year":"2015","journal-title":"Hypertension"},{"issue":"110","key":"10.1016\/j.mvr.2022.104469_bb0165","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1152\/japplphysiol.00071.2011","article-title":"Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease","volume":"2011","author":"Kenjale","year":"2011","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0170","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1159\/000468541","article-title":"Oral nitrate increases microvascular reactivity and the number of visible perfused microvessels in healthy volunteers","volume":"54","author":"Kolb","year":"2017","journal-title":"J. Vasc. Res."},{"key":"10.1016\/j.mvr.2022.104469_bb0175","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jcmg.2008.04.001","article-title":"Limb stress-rest perfusion imaging with contrast ultrasound for the assessment of peripheral arterial disease severity","volume":"1","author":"Lindner","year":"2008","journal-title":"JACC Cardiovasc. Imaging"},{"key":"10.1016\/j.mvr.2022.104469_bb0180","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/nrd2466","article-title":"The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics","volume":"7","author":"Lundberg","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.mvr.2022.104469_bb0185","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1007\/s10787-020-00689-4","article-title":"Analgesic activity and mechanism of action of a beta vulgaris dye enriched in betalains in inflammatory models in mice","volume":"28","author":"Martinez","year":"2020","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.mvr.2022.104469_bb0190","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1046\/j.1525-1497.2003.20527.x","article-title":"Depressive symptoms and lower extremity functioning in men and women with peripheral arterial disease","volume":"18","author":"McDermott","year":"2003","journal-title":"J. Gen. Intern. Med."},{"key":"10.1016\/j.mvr.2022.104469_bb0195","doi-asserted-by":"crossref","first-page":"H1425","DOI":"10.1152\/ajpheart.00232.2018","article-title":"Leg blood flow and skeletal muscle microvascular perfusion responses to submaximal exercise in peripheral arterial disease","volume":"315","author":"Meneses","year":"2018","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0200","first-page":"69","article-title":"Statistics corner: a guide to appropriate use of correlation coefficient in medical research","volume":"24","author":"Mukaka","year":"2012","journal-title":"Malawi Med. J."},{"key":"10.1016\/j.mvr.2022.104469_bb0205","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.fitote.2013.06.004","article-title":"Nutritional and functional potential of Beta vulgaris cicla and rubra","volume":"89","author":"Ninfali","year":"2013","journal-title":"Fitoterapia"},{"key":"10.1016\/j.mvr.2022.104469_bb0210","doi-asserted-by":"crossref","first-page":"H59","DOI":"10.1152\/ajpheart.00163.2017","article-title":"Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study","volume":"313","author":"Notay","year":"2017","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0215","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1161\/01.CIR.96.11.3897","article-title":"Cardiovascular and sympathetic effects of nitric oxide inhibition at rest and during static exercise in humans","volume":"96","author":"Owlya","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2022.104469_bb0220","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/07315724.2017.1401497","article-title":"Beetroot increases muscle performance and oxygenation during sustained isometric exercise, but does not alter muscle oxidative efficiency and microvascular reactivity at rest","volume":"37","author":"Papadopoulos","year":"2018","journal-title":"J. Am. Coll. Nutr."},{"issue":"132","key":"10.1016\/j.mvr.2022.104469_bb0225","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1152\/japplphysiol.00799.2021","article-title":"Effects of passive and active leg movements to interrupt sitting in mild hypercapnia on cardiovascular function in healthy adults","volume":"2022","author":"Park","year":"2022","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0230","doi-asserted-by":"crossref","first-page":"H867","DOI":"10.1152\/ajpheart.00690.2021","article-title":"Impaired microcirculatory function, mitochondrial respiration, and oxygen utilization in skeletal muscle of claudicating patients with peripheral artery disease","volume":"322","author":"Park","year":"2022","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0235","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1177\/153537020122600902","article-title":"Role of nitric oxide in central sympathetic outflow","volume":"226","author":"Patel","year":"2001","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.mvr.2022.104469_bb0240","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1152\/ajpregu.00121.2021","article-title":"Body mass-normalized moderate dose of dietary nitrate intake improves endothelial function and walking capacity in patients with peripheral artery disease","volume":"321","author":"Pekas","year":"2021","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/000331979304400101","article-title":"Functional benefits of peripheral vascular bypass surgery for patients with intermittent claudication","volume":"44","author":"Regensteiner","year":"1993","journal-title":"Angiology"},{"key":"10.1016\/j.mvr.2022.104469_bb0250","doi-asserted-by":"crossref","first-page":"277","DOI":"10.70252\/ULNG6573","article-title":"Effect of beetroot juice on moderate-intensity exercise at a constant rating of perceived exertion","volume":"8","author":"Rienks","year":"2015","journal-title":"Int. J. Exerc. Sci."},{"key":"10.1016\/j.mvr.2022.104469_bb0255","doi-asserted-by":"crossref","first-page":"93","DOI":"10.2147\/IJNRD.S7038","article-title":"Fifteen years of losartan: what have we learned about losartan that can benefit chronic kidney disease patients?","volume":"3","author":"Ripley","year":"2010","journal-title":"Int. J. Nephrol. Renovasc. Dis."},{"key":"10.1016\/j.mvr.2022.104469_bb0260","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3389\/fpubh.2017.00258","article-title":"An overview of heart rate variability metrics and norms","volume":"5","author":"Shaffer","year":"2017","journal-title":"Front. Public Health"},{"key":"10.1016\/j.mvr.2022.104469_bb0265","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/00005344-199209000-00003","article-title":"Pharmacokinetics and pharmacodynamics of benazepril in hypertensive patients with normal and impaired renal function","volume":"20","author":"Shionoiri","year":"1992","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.mvr.2022.104469_bb0270","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.atherosclerosis.2018.05.033","article-title":"Update on peripheral artery disease: epidemiology and evidence-based facts","volume":"275","author":"Shu","year":"2018","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mvr.2022.104469_bb0275","doi-asserted-by":"crossref","first-page":"H2068","DOI":"10.1152\/ajpheart.00919.2003","article-title":"Independent modification of baroreceptor and exercise pressor reflex function by nitric oxide in nucleus tractus solitarius","volume":"288","author":"Smith","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0280","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1139\/apnm-2021-0693","article-title":"A single dose of dietary nitrate supplementation protects against endothelial ischemia-reperfusion injury in early postmenopausal women","volume":"47","author":"Somani","year":"2022","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"10.1016\/j.mvr.2022.104469_bb0285","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4300\/JGME-D-12-00156.1","article-title":"Using effect size-or why the P value is not enough","volume":"4","author":"Sullivan","year":"2012","journal-title":"J. Grad. Med. Educ."},{"key":"10.1016\/j.mvr.2022.104469_bb0290","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.biopsych.2017.06.020","article-title":"Cross-sectional and longitudinal associations of chronic posttraumatic stress disorder with inflammatory and endothelial function markers in women","volume":"82","author":"Sumner","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.mvr.2022.104469_bb0295","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.cmpb.2013.07.024","article-title":"Kubios HRV\u2013heart rate variability analysis software","volume":"113","author":"Tarvainen","year":"2014","journal-title":"Comput. Methods Prog. Biomed."},{"key":"10.1016\/j.mvr.2022.104469_bb0300","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","article-title":"Heart rate variability. Standards of measurement, physiological interpretation, and clinical use","volume":"17","year":"1996","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.mvr.2022.104469_bb0305","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","article-title":"Heart rate variability: standards of measurement, physiological interpretation and clinical use","volume":"93","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2022.104469_bb0310","doi-asserted-by":"crossref","first-page":"R1121","DOI":"10.1152\/ajpregu.00206.2010","article-title":"Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise","volume":"299","author":"Vanhatalo","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0315","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3945\/ajcn.115.116244","article-title":"Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study","volume":"103","author":"Velmurugan","year":"2016","journal-title":"Am. J. Clin. Nutr."},{"issue":"127","key":"10.1016\/j.mvr.2022.104469_bb0320","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1152\/japplphysiol.01053.2018","article-title":"Effect of acute dietary nitrate supplementation on sympathetic vasoconstriction at rest and during exercise","volume":"2019","author":"de Vries","year":"2019","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0325","first-page":"11","article-title":"Acute dietary nitrate supplementation improves flow mediated dilatation of the superficial femoral artery in healthy older males","author":"Walker","year":"2019","journal-title":"Nutrients"},{"issue":"115","key":"10.1016\/j.mvr.2022.104469_bb0330","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1152\/japplphysiol.00372.2013","article-title":"Beetroot juice and exercise: pharmacodynamic and dose-response relationships","volume":"2013","author":"Wylie","year":"2013","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0335","doi-asserted-by":"crossref","first-page":"4977","DOI":"10.1113\/jphysiol.2009.177204","article-title":"Inhibition of nitric oxide synthase evokes central sympatho-excitation in healthy humans","volume":"587","author":"Young","year":"2009","journal-title":"J. Physiol."},{"key":"10.1016\/j.mvr.2022.104469_bb0340","doi-asserted-by":"crossref","DOI":"10.1111\/micc.12525","article-title":"Dietary nitrate improves muscle microvascular reactivity and lowers blood pressure at rest and during isometric exercise in untreated hypertensives","volume":"26","author":"Zafeiridis","year":"2019","journal-title":"Microcirculation"}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286222001613?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286222001613?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T06:00:26Z","timestamp":1758434426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286222001613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":68,"alternative-id":["S0026286222001613"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2022.104469","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Moderate dose of dietary nitrate improves skeletal muscle microvascular function in patients with peripheral artery disease","name":"articletitle","label":"Article Title"},{"value":"Microvascular Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mvr.2022.104469","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104469"}}