{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:35:02Z","timestamp":1789601702034,"version":"build-2803163510"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.mvr.2025.104805","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:11:05Z","timestamp":1742256665000},"page":"104805","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Interplay between platelet and T lymphocyte after coronary artery bypass grafting (CABG): Evidence for platelet mediated post-CABG immunomodulation"],"prefix":"10.1016","volume":"160","author":[{"given":"Fateme","family":"Farhid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehteramolsadat","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faranak","family":"Kargar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehran","family":"Ghasemzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0005","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/MOH.0000000000000331","article-title":"P-selectin glycoprotein ligand-1 in T cells","volume":"24","author":"Abadier","year":"2017","journal-title":"Curr. Opin. Hematol."},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0010","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s11239-022-02729-y","article-title":"Stable CAD patients show higher levels of platelet-borne TGF-\u03b21 associated with a superior pro-inflammatory state than the pro-aggregatory status; evidence highlighting the importance of platelet-derived TGF-\u03b21 in atherosclerosis","volume":"55","author":"Ahmadi","year":"2023","journal-title":"J. Thromb. Thrombolysis"},{"issue":"6","key":"10.1016\/j.mvr.2025.104805_bb0015","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1177\/096721090201000612","article-title":"Effects of coronary artery bypass grafting on cellular immunity with or without cardiopulmonary bypass: changes in lymphocytes subsets","volume":"10","author":"Akbas","year":"2002","journal-title":"Card. Surg. (London, England)"},{"issue":"12","key":"10.1016\/j.mvr.2025.104805_bb0020","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.it.2015.10.005","article-title":"Exit strategies: S1P signaling and T cell migration","volume":"36","author":"Baeyens","year":"2015","journal-title":"Trends Immunol."},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0025","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jtcvs.2007.01.055","article-title":"Comparison of early platelet activation in patients undergoing on-pump versus off-pump coronary artery bypass surgery","volume":"134","author":"Ballotta","year":"2007","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"2","key":"10.1016\/j.mvr.2025.104805_bb0030","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S1010-7940(03)00295-1","article-title":"Biological effects of off-pump vs. on-pump coronary artery surgery: focus on inflammation, hemostasis and oxidative stress","volume":"24","author":"Biglioli","year":"2003","journal-title":"Eur. J. Cardiothorac. Surg."},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0035","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1093\/ajcp\/87.5.626","article-title":"Altered lymphocyte subsets during cardiopulmonary bypass","volume":"87","author":"Brody","year":"1987","journal-title":"Am. J. Clin. Pathol."},{"issue":"4","key":"10.1016\/j.mvr.2025.104805_bb0040","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1136\/gut.2008.158824","article-title":"Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue","volume":"58","author":"Chaput","year":"2009","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.mvr.2025.104805_bb0045","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1182\/blood-2003-05-1679","article-title":"Cross-linking of P-selectin glycoprotein ligand-1 induces death of activated T cells","volume":"104","author":"Chen","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.mvr.2025.104805_bb0050","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40364-020-00207-2","article-title":"Role of platelet biomarkers in inflammatory response","volume":"8","author":"Chen","year":"2020","journal-title":"Biomark. Res."},{"issue":"12","key":"10.1016\/j.mvr.2025.104805_bb0055","doi-asserted-by":"crossref","DOI":"10.32604\/biocell.2023.043084","article-title":"Effects of platelets on characteristics of lymphocytes cultured in vitro and optimization of adoptive immunotherapy","volume":"47","author":"Chen","year":"2023","journal-title":"Biocell"},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0060","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00441-017-2780-z","article-title":"The neutrophil: one cell on many missions or many cells with different agendas?","volume":"371","author":"Christoffersson","year":"2018","journal-title":"Cell Tissue Res."},{"issue":"7","key":"10.1016\/j.mvr.2025.104805_bb0065","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/s41590-021-00949-7","article-title":"Not-so-opposite ends of the spectrum: CD8(+) T cell dysfunction across chronic infection, cancer and autoimmunity","volume":"22","author":"Collier","year":"2021","journal-title":"Nat. Immunol."},{"issue":"42","key":"10.1016\/j.mvr.2025.104805_bb0070","first-page":"716","article-title":"The treatment of coronary artery disease","volume":"119","author":"Doenst","year":"2022","journal-title":"Dtsch. Arztebl. Int."},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0075","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ejcts.2006.03.029","article-title":"Hyporesponsiveness of T cell subsets after cardiac surgery: a product of altered cell function or merely a result of absolute cell count changes in peripheral blood?","volume":"30","author":"Franke","year":"2006","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.mvr.2025.104805_bb0080","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12959-019-0209-5","article-title":"Down-regulation of platelet adhesion receptors is a controlling mechanism of thrombosis, while also affecting post-transfusion efficacy of stored platelets","volume":"17","author":"Hosseini","year":"2019","journal-title":"Thromb. J."},{"key":"10.1016\/j.mvr.2025.104805_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.mvr.2024.104669","article-title":"Coronary artery bypass grafting (CABG) induces pro-inflammatory and immunomodulatory phenotype of platelets in the absence of a pro-aggregatory state","volume":"153","author":"Hosseini","year":"2024","journal-title":"Microvasc. Res."},{"issue":"12","key":"10.1016\/j.mvr.2025.104805_bb0090","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1160\/TH10-05-0308","article-title":"Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus","volume":"104","author":"Hu","year":"2010","journal-title":"Thromb. Haemost."},{"issue":"15","key":"10.1016\/j.mvr.2025.104805_bb0095","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1182\/blood-2012-05-427799","article-title":"Elevated serum soluble CD40 ligand in cancer patients may play an immunosuppressive role","volume":"120","author":"Huang","year":"2012","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.29252\/IJMR-060101","article-title":"Complications of coronary artery bypass grafting","volume":"6","author":"Hussain","year":"2019","journal-title":"Int. J. Med. Rev."},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0105","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0003-4975(10)62074-7","article-title":"The effect of cardiopulmonary bypass on T cells and their subpopulations","volume":"44","author":"Ide","year":"1987","journal-title":"Ann. Thorac. Surg."},{"issue":"8","key":"10.1016\/j.mvr.2025.104805_bb0110","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1080\/09537104.2018.1542122","article-title":"Increased platelet reactivity and platelet-leukocyte aggregation after elective coronary bypass surgery","volume":"30","author":"Ivert","year":"2019","journal-title":"Platelets"},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0115","doi-asserted-by":"crossref","first-page":"25","DOI":"10.14712\/18059694.2017.4","article-title":"The effect of cardiac surgery on peripheral blood lymphocyte populations","volume":"51","author":"Jankovicov\u00e1","year":"2008","journal-title":"Acta Med. (Hradec Kralove)"},{"issue":"4","key":"10.1016\/j.mvr.2025.104805_bb0120","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jvn.2021.07.005","article-title":"The value of prophylactic antibiotics in coronary artery bypass graft surgery: a review of literature","volume":"39","author":"Jannati","year":"2021","journal-title":"J. Vasc. Nurs."},{"issue":"1","key":"10.1016\/j.mvr.2025.104805_bb0125","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/cei.12396","article-title":"Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection","volume":"178","author":"Jenabian","year":"2014","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0130","doi-asserted-by":"crossref","first-page":"186","DOI":"10.5539\/gjhs.v6n3p186","article-title":"On pump coronary artery bypass graft surgery versus off pump coronary artery bypass graft surgery: a review","volume":"6","author":"Khan","year":"2014","journal-title":"Global J. Health Sci."},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0135","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00281-019-00744-5","article-title":"CD8(+) T cell exhaustion","volume":"41","author":"Kurachi","year":"2019","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.mvr.2025.104805_bb0140","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.immunol.24.021605.090737","article-title":"Transforming growth factor-beta regulation of immune responses","volume":"24","author":"Li","year":"2006","journal-title":"Annu. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0145","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.4049\/jimmunol.174.5.2680","article-title":"Platelet factor 4 differentially modulates CD4+CD25+ (regulatory) versus CD4+CD25- (nonregulatory) T cells","volume":"174","author":"Liu","year":"2005","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.mvr.2025.104805_bb0150","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1038\/ni1275","article-title":"Immune cell migration in inflammation: present and future therapeutic targets","volume":"6","author":"Luster","year":"2005","journal-title":"Nat. Immunol."},{"issue":"8","key":"10.1016\/j.mvr.2025.104805_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0236966","article-title":"Platelet-T cell aggregates in lung cancer patients: implications for thrombosis","volume":"15","author":"Meikle","year":"2020","journal-title":"PLoS One"},{"issue":"69","key":"10.1016\/j.mvr.2025.104805_bb0160","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abi4613","article-title":"Transforming growth factor-\u03b21 in regulatory T cell biology","volume":"7","author":"Moreau","year":"2022","journal-title":"Sci. Immunol."},{"issue":"21","key":"10.1016\/j.mvr.2025.104805_bb0165","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1161\/CIRCULATIONAHA.108.785105","article-title":"A randomized trial of on-pump beating heart and conventional cardioplegic arrest in coronary artery bypass surgery patients with impaired left ventricular function using cardiac magnetic resonance imaging and biochemical markers","volume":"118","author":"Pegg","year":"2008","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0170","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4161\/onci.18852","article-title":"Comprehensive analysis of current approaches to inhibit regulatory T cells in cancer","volume":"1","author":"Pere","year":"2012","journal-title":"Oncoimmunology"},{"issue":"2","key":"10.1016\/j.mvr.2025.104805_bb0175","doi-asserted-by":"crossref","DOI":"10.3390\/biology11020224","article-title":"Platelet-leucocyte aggregates as novel biomarkers in cardiovascular diseases","volume":"11","author":"Pluta","year":"2022","journal-title":"Biology"},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0180","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2217\/fca-2019-0049","article-title":"Postoperative complications associated with coronary artery bypass graft surgery and their therapeutic interventions","volume":"16","author":"Pooria","year":"2020","journal-title":"Futur. Cardiol."},{"issue":"2","key":"10.1016\/j.mvr.2025.104805_bb0185","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.atherosclerosis.2014.10.021","article-title":"Platelet expression of transforming growth factor beta 1 is enhanced and associated with cardiovascular prognosis in patients with acute coronary syndrome","volume":"237","author":"Rath","year":"2014","journal-title":"Atherosclerosis"},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0190","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.ejcts.2009.12.002","article-title":"The cellular immunological responses of patients undergoing coronary artery bypass grafting compared with those of patients undergoing valve replacement","volume":"37","author":"Rudensky","year":"2010","journal-title":"Eur. J. Cardiothorac. Surg."},{"issue":"3","key":"10.1016\/j.mvr.2025.104805_bb0195","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5114\/ceji.2021.109171","article-title":"The posttraumatic response of CD4+ regulatory T cells is modulated by direct cell-cell contact via CD40L- and P-selectin-dependent pathways","volume":"46","author":"Rupp","year":"2021","journal-title":"Cent. Eur. J. Immunol."},{"issue":"6","key":"10.1016\/j.mvr.2025.104805_bb0200","first-page":"1219","article-title":"Ectosomes released by platelets induce differentiation of CD4+T cells into T regulatory cells","volume":"112","author":"Sadallah","year":"2014","journal-title":"Thromb. Haemost."},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0205","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.4049\/jimmunol.178.5.2932","article-title":"CD4+ and CD8+ T cell survival is regulated differentially by protein kinase C\u03b8, c-Rel, and protein kinase B1","volume":"178","author":"Saibil","year":"2007","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.mvr.2025.104805_bb0210","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.jcrc.2009.06.009","article-title":"Reduced expression of systemic proinflammatory and myocardial biomarkers after off-pump versus on-pump coronary artery bypass surgery: a prospective randomized study","volume":"25","author":"Serrano","year":"2010","journal-title":"J. Crit. Care"},{"issue":"4","key":"10.1016\/j.mvr.2025.104805_bb0215","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/S0003-4975(99)00729-8","article-title":"Human cytokine responses to coronary artery bypass grafting with and without cardiopulmonary bypass","volume":"68","author":"Str\u00fcber","year":"1999","journal-title":"Ann. Thorac. Surg."},{"issue":"5","key":"10.1016\/j.mvr.2025.104805_bb0220","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.immuni.2016.04.015","article-title":"PSGL-1 is an immune checkpoint regulator that promotes T cell exhaustion","volume":"44","author":"Tinoco","year":"2016","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.mvr.2025.104805_bb0225","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1080\/140174302762659067","article-title":"Soluble adhesion molecules in coronary surgery and cardiopulmonary bypass with pump prime aprotinin","volume":"36","author":"Wei","year":"2002","journal-title":"Scand. Cardiovasc. J."},{"key":"10.1016\/j.mvr.2025.104805_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.893609","article-title":"Size distribution of microparticles: a new parameter to predict acute lung injury after cardiac surgery with cardiopulmonary bypass","volume":"9","author":"Yuan","year":"2022","journal-title":"Front. Cardiovasc. Med."}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002628622500024X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002628622500024X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T13:01:40Z","timestamp":1749214900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002628622500024X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":46,"alternative-id":["S002628622500024X"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2025.104805","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interplay between platelet and T lymphocyte after coronary artery bypass grafting (CABG): Evidence for platelet mediated post-CABG immunomodulation","name":"articletitle","label":"Article Title"},{"value":"Microvascular Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mvr.2025.104805","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104805"}}