{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:37:52Z","timestamp":1791819472769,"version":"4.3.4"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microvascular Research"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.mvr.2026.104927","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T16:23:40Z","timestamp":1772555020000},"page":"104927","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Influence of intravascular albumin on the capillary leakage of fluid in humans"],"prefix":"10.1016","volume":"165","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1528-3803","authenticated-orcid":false,"given":"Robert G.","family":"Hahn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mvr.2026.104927_bb0005","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s40262-025-01500-9","article-title":"Volume kinetics of Gelofusine 4% during vascular surgery","volume":"64","author":"Balan","year":"2025","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.mvr.2026.104927_bb0010","series-title":"Oxford Textbook of Anaesthesia","first-page":"881","article-title":"Regional anaesthesia of the trunk","author":"Berrill","year":"2017"},{"key":"10.1016\/j.mvr.2026.104927_bb0015","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1097\/TA.0000000000003013","article-title":"Transcapillary refill: the physiology underlying fluid reabsorption","volume":"90","author":"Dull","year":"2021","journal-title":"J. Trauma Acute Care Surg."},{"key":"10.1016\/j.mvr.2026.104927_bb0020","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1177\/1060028020907084","article-title":"The revised starling equation: the debate of albumin versus crystalloids continues","volume":"54","author":"Erstad","year":"2020","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.mvr.2026.104927_bb0025","doi-asserted-by":"crossref","first-page":"112154","DOI":"10.1016\/j.jclinane.2026.112154","article-title":"Endothelial glycocalyx in perioperative medicine current understanding and future direction","volume":"110","author":"Farag","year":"2026","journal-title":"J. Clin. Anesth."},{"key":"10.1016\/j.mvr.2026.104927_bb0030","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1213\/ANE.0000000000005802","article-title":"Plasma volume expansion and fluid kinetics of 20% albumin during general anesthesia and surgery lasting for more than 5 hours","volume":"134","author":"Gunnstr\u00f6m","year":"2022","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mvr.2026.104927_bb0035","first-page":"310","article-title":"Effects of diet, habitual water intake and increased hydration on body fluid volumes and urinary analysis of renal fluid retention in healthy volunteers","volume":"48","author":"Hahn","year":"2021","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.mvr.2026.104927_bb0040","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/1440-1681.13439","article-title":"Renal water conservation and the volume kinetics of fluid-induced diuresis; a retrospective analysis of two cohorts of elderly men","volume":"48","author":"Hahn","year":"2021","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.mvr.2026.104927_bb0045","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s12871-024-02494-w","article-title":"Accelerated lymph flow from infusion of crystalloid fluid during general anesthesia","volume":"24","author":"Hahn","year":"2024","journal-title":"BMC Anesthesiol."},{"key":"10.1016\/j.mvr.2026.104927_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijoa.2023.103963","article-title":"Maldistribution of fluid in preeclampsia; a retrospective kinetic analysis","volume":"57","author":"Hahn","year":"2024","journal-title":"Int. J. Obstet. Anesth."},{"key":"10.1016\/j.mvr.2026.104927_bb0055","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3390\/fluids10040086","article-title":"Volume kinetic analysis in living humans; background history and answers to 15 questions in physiology and medicine","volume":"10","author":"Hahn","year":"2025","journal-title":"Fluids"},{"key":"10.1016\/j.mvr.2026.104927_bb0060","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.70623","article-title":"Constant plasma volume and colloid osmotic pressure after infusion of albumin 20%: a plasma volume steady state after infusion of albumin 20%: a secondary analysis","volume":"13","author":"Hahn","year":"2025","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.mvr.2026.104927_bb0065","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/jcph.6182","article-title":"Capillary filtration of plasma is accelerated during general anesthesia: a secondary volume kinetic analysis","volume":"65","author":"Hahn","year":"2025","journal-title":"J. Clin. Pharmacol."},{"key":"10.1016\/j.mvr.2026.104927_bb0070","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s00424-025-03135-y","article-title":"When does the \u201cthird space\u201d open?","volume":"478","author":"Hahn","year":"2026","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.mvr.2026.104927_bb0075","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s40635-021-00407-6","article-title":"Interstitial washdown and vascular albumin refill during fluid infusion: novel kinetic analysis from three clinical trials","volume":"9","author":"Hahn","year":"2021","journal-title":"Intens. Care Med. Exp."},{"key":"10.1016\/j.mvr.2026.104927_bb0080","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1213\/ANE.0000000000005315","article-title":"Elevated plasma concentrations of syndecan-1 do not correlate with the capillary leakage of 20% albumin","volume":"132","author":"Hahn","year":"2021","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mvr.2026.104927_bb0085","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jointm.2025.08.008","article-title":"Vasoactive drugs and the distribution of crystalloid fluid during acute sepsis","volume":"6","author":"Hahn","year":"2025","journal-title":"J. Intens. Med."},{"key":"10.1016\/j.mvr.2026.104927_bb0090","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1213\/ANE.0000000000004047","article-title":"Long intravascular persistence of 20% albumin in postoperative patients","volume":"129","author":"Hasselgren","year":"2019","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.mvr.2026.104927_bb0095","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1042\/CS20040303","article-title":"Volume expansion and plasma protein clearance during intravenous infusion of 5% albumin and autologous plasma","volume":"106","author":"Hedin","year":"2005","journal-title":"Clin. Sci."},{"key":"10.1016\/j.mvr.2026.104927_bb0100","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1007\/s00421-014-3088-2","article-title":"Markers of the hydration process during volume modification with habitual high or low daily fluid intakes","volume":"115","author":"Johnson","year":"2015","journal-title":"Eur. J. Appl. Physiol."},{"key":"10.1016\/j.mvr.2026.104927_bb0105","first-page":"8","article-title":"Hormonal and thirst modulated maintenance of fluid balance in young women with different levels of habitual fluid consumption","volume":"18","author":"Johnson","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.mvr.2026.104927_bb0110","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1186\/s13054-016-1536-6","article-title":"Simultaneous assessment of the synthesis rate and transcapillary escape rate of albumin in inflammation and surgery","volume":"20","author":"Kom\u00e1romi","year":"2016","journal-title":"Crit. Care"},{"key":"10.1016\/j.mvr.2026.104927_bb0115","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0300-9572(76)90028-9","article-title":"Plasma volume expansion after infusion of 5%, 20% and 25% albumin solutions in patients","volume":"5","author":"Lamke","year":"1976","journal-title":"Resuscitation"},{"key":"10.1016\/j.mvr.2026.104927_bb0120","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/cvr\/cvq062","article-title":"Microvascular fluid exchange and the revised Starling principle","volume":"87","author":"Levick","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mvr.2026.104927_bb0125","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.bja.2018.04.023","article-title":"Volume kinetics of Ringer\u2019s lactate solution in acute inflammatory disease","volume":"121","author":"Li","year":"2018","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.mvr.2026.104927_bb0130","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1097\/00000658-196310000-00016","article-title":"Transcapillary refilling after hemorrhage in normal man: basal rates and volumes: effect of norepinephrine","volume":"158","author":"Lister","year":"1963","journal-title":"Ann. Surg."},{"key":"10.1016\/j.mvr.2026.104927_bb0135","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1748-1716.1976.tb10187.x","article-title":"Beta adrenergic dilator component of the sympathetic vascular response in skeletal muscle. Influence on the micro-circulation and on transcapillary exchange","volume":"96","author":"Lundvall","year":"1976","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.mvr.2026.104927_bb0140","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1113\/jphysiol.1985.sp015620","article-title":"The effects of native and modified bovine serum albumin on the permeability of frog mesenteric capillaries","volume":"360","author":"Michel","year":"1985","journal-title":"J. Physiol."},{"key":"10.1016\/j.mvr.2026.104927_bb0145","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1056\/NEJMra1208627","article-title":"Resuscitation fluids","volume":"369","author":"Myburgh","year":"2013","journal-title":"N. Engl. J. Med."},{"issue":"8","key":"10.1016\/j.mvr.2026.104927_bb0150","first-page":"14","article-title":"Norepinephrine causes a pressure-dependent plasma volume decrease in clinical vasodilatory shock","volume":"54","author":"Nygren","year":"2010","journal-title":"Acta Anaesthesiol. Scand."},{"key":"10.1016\/j.mvr.2026.104927_bb0155","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1017\/S0007114512003601","article-title":"Hydration biomarkers in free\u2013living adults with different levels of habitual fluid consumption","volume":"109","author":"Perrier","year":"2013","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.mvr.2026.104927_bb0160","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1161\/CIRCULATIONAHA.106.684852","article-title":"Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia","volume":"116","author":"Rehm","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.mvr.2026.104927_bb0165","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s13054-019-2477-7","article-title":"Albumin infusion rate and plasma volume expansion: a randomized clinical trial in postoperative patients after major surgery","volume":"23","author":"Statkevicius","year":"2019","journal-title":"Crit. Care"},{"key":"10.1016\/j.mvr.2026.104927_bb0170","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/bja\/aer515","article-title":"Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy","volume":"108","author":"Woodcock","year":"2012","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.mvr.2026.104927_bb0175","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2025.1662177","article-title":"Effects of concentrated urine on complications and plasma creatinine; a prospective study in elective non-cardiac surgery patients","volume":"12","author":"Xie","year":"2025","journal-title":"Front. Med."},{"key":"10.1016\/j.mvr.2026.104927_bb0180","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/aas.14074","article-title":"Kinetics of 5% and 20% albumin: a controlled crossover trial in volunteers","volume":"66","author":"Zdolsek","year":"2022","journal-title":"Acta Anaesthesiol. Scand."},{"key":"10.1016\/j.mvr.2026.104927_bb0185","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/micc.12278","article-title":"Sphingosine-1-phosphate maintains normal vascular permeability by preserving endothelial surface glycocalyx in intact microvessels","volume":"23","author":"Zhang","year":"2016","journal-title":"Microcirculation"}],"container-title":["Microvascular Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286226000270?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026286226000270?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T17:41:52Z","timestamp":1774028512000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026286226000270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":37,"alternative-id":["S0026286226000270"],"URL":"https:\/\/doi.org\/10.1016\/j.mvr.2026.104927","relation":{},"ISSN":["0026-2862"],"issn-type":[{"value":"0026-2862","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of intravascular albumin on the capillary leakage of fluid in humans","name":"articletitle","label":"Article Title"},{"value":"Microvascular Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mvr.2026.104927","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"104927"}}