{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:28:08Z","timestamp":1791278888311,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.nano.2009.01.014","type":"journal-article","created":{"date-parts":[[2009,2,14]],"date-time":"2009-02-14T15:11:32Z","timestamp":1234624292000},"page":"136-142","source":"Crossref","is-referenced-by-count":306,"title":["Enhancement of radiation effects by gold nanoparticles for superficial radiation therapy"],"prefix":"10.1016","volume":"5","author":[{"given":"Wan Nordiana","family":"Rahman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nour","family":"Bishara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"Ackerly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng Fa","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Price","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Davidson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshi","family":"Geso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nano.2009.01.014_bib1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1118\/1.595378","article-title":"Radiation dose enhancement in tumors with iodine","volume":"10","author":"Mello","year":"1983","journal-title":"Med Phys"},{"key":"10.1016\/j.nano.2009.01.014_bib2","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1088\/0031-9155\/44\/8\/308","article-title":"Dose distributions using kilovoltage x-rays and dose enhancement from iodine contrast agents","volume":"44","author":"Mesa","year":"1999","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.nano.2009.01.014_bib3","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1088\/0031-9155\/47\/14\/305","article-title":"Tumour dose enhancement using modified megavoltage photon beams and contrast media","volume":"47","author":"Robar","year":"2002","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.nano.2009.01.014_bib4","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/sj.bjc.6601951","article-title":"Synchrotron radiation based experimental determination of the optimal energy for cell radiotoxicity enhancement following photoelectric effect on stable iodinated compounds","volume":"91","author":"Corde","year":"2004","journal-title":"Br J Cancer"},{"key":"10.1016\/j.nano.2009.01.014_bib5","doi-asserted-by":"crossref","first-page":"S540","DOI":"10.1016\/S1076-6332(03)80287-8","article-title":"Enhanced radio sensitivity with iodinated contrast agents using monochromatic synchrotron x rays on human cancerous cells","volume":"9","author":"Esteve","year":"2002","journal-title":"Acad Radiol"},{"key":"10.1016\/j.nano.2009.01.014_bib6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1259\/0007-1285-60-710-201","article-title":"Iodinated contrast agents as radiosensitisers","volume":"60","author":"Dawson","year":"1987","journal-title":"Br J Radiol"},{"key":"10.1016\/j.nano.2009.01.014_bib7","doi-asserted-by":"crossref","first-page":"144","DOI":"10.2307\/3575225","article-title":"Iodine contrast medium sensitizes cultured mammalian cells to x rays but not to \u03b3 rays","volume":"84","author":"Matsudaira","year":"1980","journal-title":"Radiat Res"},{"key":"10.1016\/j.nano.2009.01.014_bib8","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1088\/0031-9155\/49\/18\/N03","article-title":"The use of gold nanoparticles to enhance radiotherapy in mice","volume":"49","author":"Hainfeld","year":"2004","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.nano.2009.01.014_bib9","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1259\/bjr\/13169882","article-title":"Gold nanoparticles: a new x-ray contrast agent","volume":"79","author":"Hainfeld","year":"2006","journal-title":"Br J Radiol"},{"key":"10.1016\/j.nano.2009.01.014_bib10","first-page":"1808","article-title":"Synchrotron x-ray synthesized gold nanoparticles for tumor therapy","volume":"879","author":"Chien","year":"2007","journal-title":"AIP Conf Proc"},{"key":"10.1016\/j.nano.2009.01.014_bib11","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1080\/09553000050151637","article-title":"Gold microspheres: a selective technique for producing biologically effective dose enhancement","volume":"76","author":"Herold","year":"2000","journal-title":"Int J Radiat Biol"},{"key":"10.1016\/j.nano.2009.01.014_bib12","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1088\/0031-9155\/50\/15\/N01","article-title":"Estimation of tumour dose enhancement due to gold nanoparticles during typical radiation treatments: a preliminary Monte Carlo study","volume":"50","author":"Cho","year":"2005","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.nano.2009.01.014_bib13","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1002\/smll.200700794","article-title":"Enhancement of radiation cytotoxicity in breast-cancer cells by localized attachment of gold nanoparticles","volume":"4","author":"Kong","year":"2008","journal-title":"Small"},{"key":"10.1016\/j.nano.2009.01.014_bib14","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.ijrobp.2005.04.009","article-title":"Irradiation in presence of iodinated contrast agent results in radiosensitization of endothelial cells: consequences for computed tomography therapy","volume":"62","author":"Joubert","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.nano.2009.01.014_bib15","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1021\/nn800330a","article-title":"Uptake and intracellular fate of surface-modified gold nanoparticles","volume":"2","author":"Nativo","year":"2008","journal-title":"ACS Nano"},{"key":"10.1016\/j.nano.2009.01.014_bib16","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1021\/nl052396o","article-title":"Determining the size and shape dependence of gold nanoparticles uptake into mammalian cells","volume":"4","author":"Chitrani","year":"2006","journal-title":"Nano Lett"},{"key":"10.1016\/j.nano.2009.01.014_bib17","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.3390\/s8042306","article-title":"Compound cellular imaging of laser scanning confocal microscopy by using gold nanoparticles and dyes","volume":"8","author":"Tsai","year":"2008","journal-title":"Sensors"},{"key":"10.1016\/j.nano.2009.01.014_bib18","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.nano.2007.03.005","article-title":"Cell selective response to gold nanoparticles","volume":"3","author":"Patra","year":"2007","journal-title":"Nanomedicine"},{"key":"10.1016\/j.nano.2009.01.014_bib19","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1021\/bc034189q","article-title":"Cellular trajectories of peptide-modified gold particle complexes: comparison of nuclear localisation signals and peptide transduction domains","volume":"15","author":"Tkachenko","year":"2004","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.nano.2009.01.014_bib20","author":"Hubbell"},{"key":"10.1016\/j.nano.2009.01.014_bib21","series-title":"The physics of radiation therapy","author":"Khan","year":"2003"},{"key":"10.1016\/j.nano.2009.01.014_bib22","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1111\/j.1349-7006.2008.00827.x","article-title":"Increased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose clinical electron beams on tumor-bearing mice","volume":"99","author":"Chang","year":"2008","journal-title":"Cancer Sci"},{"key":"10.1016\/j.nano.2009.01.014_bib23","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.nimb.2005.01.077","article-title":"Nuclear microprobe determination of platinum quantitative distribution in rat brain tumors after cisplatin or carboplatin injection for PAT treatment of glioma","volume":"B231","author":"Ortega","year":"2005","journal-title":"Nucl Instrum Methods"},{"key":"10.1016\/j.nano.2009.01.014_bib24","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1002\/(SICI)1097-0215(19981123)78:5<654::AID-IJC21>3.0.CO;2-L","article-title":"Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-Wiggler-generated x-rays","volume":"78","author":"Laissue","year":"1998","journal-title":"Int J Cancer"}],"container-title":["Nanomedicine: Nanotechnology, Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963409000525?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1549963409000525?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T20:59:29Z","timestamp":1545425969000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1549963409000525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S1549963409000525"],"URL":"https:\/\/doi.org\/10.1016\/j.nano.2009.01.014","relation":{},"ISSN":["1549-9634"],"issn-type":[{"value":"1549-9634","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}